CA3002962A1 - Protein quantitation in multicellular tissue specimens - Google Patents

Protein quantitation in multicellular tissue specimens Download PDF

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Publication number
CA3002962A1
CA3002962A1 CA3002962A CA3002962A CA3002962A1 CA 3002962 A1 CA3002962 A1 CA 3002962A1 CA 3002962 A CA3002962 A CA 3002962A CA 3002962 A CA3002962 A CA 3002962A CA 3002962 A1 CA3002962 A1 CA 3002962A1
Authority
CA
Canada
Prior art keywords
protein
component
biospecimen
heterogeneous
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3002962A
Other languages
English (en)
French (fr)
Inventor
Daniel C. Liebler
Lisa J. Zimmerman
Robbert J.C. Slebos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
Original Assignee
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanderbilt University filed Critical Vanderbilt University
Publication of CA3002962A1 publication Critical patent/CA3002962A1/en
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3002962A 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens Pending CA3002962A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562251604P 2015-11-05 2015-11-05
US62/251,604 2015-11-05
PCT/US2016/028426 WO2017078787A1 (en) 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens

Publications (1)

Publication Number Publication Date
CA3002962A1 true CA3002962A1 (en) 2017-05-11

Family

ID=58662934

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3002962A Pending CA3002962A1 (en) 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens

Country Status (5)

Country Link
US (1) US11047860B2 (enExample)
EP (1) EP3371605B1 (enExample)
JP (1) JP6742034B2 (enExample)
CA (1) CA3002962A1 (enExample)
WO (1) WO2017078787A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7728250B2 (ja) * 2019-09-19 2025-08-22 ヤンセン バイオテツク，インコーポレーテツド 分子コンジュゲート及び共役の示差的特徴付けのための材料及び方法
KR20230026434A (ko) * 2020-06-18 2023-02-24 리제너론 파아마슈티컬스, 인크. 미처리된 c-말단 리신을 정확하게 측정하기 위한 중질 펩티드 접근법
CN112150044B (zh) * 2020-11-04 2022-04-22 南京大学 基于高分辨率质谱的污水厂含氮有机物去除效果评价方法
JP7679879B2 (ja) * 2021-06-17 2025-05-20 コニカミノルタ株式会社 定量方法および標識方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5725481A (en) * 1996-05-17 1998-03-10 A. Fem Medical Corporation Method and apparatus for collecting vaginal fluid and exfoliated vaginal cells for diagnostic purposes
EP1711618B1 (en) * 2003-12-23 2010-08-04 Mount Sinai Hospital Corporation Methods for detecting markers associated with endometrial disease or phase
US20070019854A1 (en) * 2005-05-10 2007-01-25 Bioimagene, Inc. Method and system for automated digital image analysis of prostrate neoplasms using morphologic patterns
JP5240739B2 (ja) 2007-04-13 2013-07-17 オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー
WO2010083252A2 (en) 2009-01-14 2010-07-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ratio based biomarkers and methods of use thereof
EP2309262A1 (en) 2009-10-06 2011-04-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for quantifying biomolecules
US9777334B2 (en) 2012-04-30 2017-10-03 The Research Foundation for State University of New York Cancer blood test using BC200 RNA isolated from peripheral blood for diagnosis and treatment of invasive breast cancer
CA2893158A1 (en) * 2012-11-30 2014-06-05 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
EP3092495B1 (en) 2014-01-06 2020-11-25 Expression Pathology, Inc. Srm assay for pd-l1

Also Published As

Publication number Publication date
JP6742034B2 (ja) 2020-08-19
WO2017078787A1 (en) 2017-05-11
EP3371605A4 (en) 2019-05-01
US20190154699A1 (en) 2019-05-23
EP3371605A1 (en) 2018-09-12
JP2018536175A (ja) 2018-12-06
US11047860B2 (en) 2021-06-29
EP3371605B1 (en) 2021-06-23

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Effective date: 20210326