JP2018532782A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018532782A5 JP2018532782A5 JP2018541534A JP2018541534A JP2018532782A5 JP 2018532782 A5 JP2018532782 A5 JP 2018532782A5 JP 2018541534 A JP2018541534 A JP 2018541534A JP 2018541534 A JP2018541534 A JP 2018541534A JP 2018532782 A5 JP2018532782 A5 JP 2018532782A5
- Authority
- JP
- Japan
- Prior art keywords
- autoantigen
- kit according
- administration
- boost
- immune response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000028993 immune response Effects 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 7
- 229960005486 vaccine Drugs 0.000 claims 7
- 102000003802 alpha-Synuclein Human genes 0.000 claims 5
- 108090000185 alpha-Synuclein Proteins 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000005862 Angiotensin II Human genes 0.000 claims 2
- 101800000733 Angiotensin-2 Proteins 0.000 claims 2
- 102000016607 Diphtheria Toxin Human genes 0.000 claims 2
- 108010053187 Diphtheria Toxin Proteins 0.000 claims 2
- 101001098868 Homo sapiens Proprotein convertase subtilisin/kexin type 9 Proteins 0.000 claims 2
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 claims 2
- 102100038955 Proprotein convertase subtilisin/kexin type 9 Human genes 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 229950006323 angiotensin ii Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 2
- 229960000814 tetanus toxoid Drugs 0.000 claims 2
- 238000002255 vaccination Methods 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 101710172072 Kexin Proteins 0.000 claims 1
- 108090000787 Subtilisin Proteins 0.000 claims 1
- 102000019355 Synuclein Human genes 0.000 claims 1
- 108050006783 Synuclein Proteins 0.000 claims 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical group [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023136194A JP7628333B2 (ja) | 2015-11-03 | 2023-08-24 | ヒト患者における自己抗原に対するワクチン接種法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15192794 | 2015-11-03 | ||
| EP15192794.4 | 2015-11-03 | ||
| PCT/EP2016/076372 WO2017076873A1 (en) | 2015-11-03 | 2016-11-02 | Method for vaccination against a self-antigen in a human patient |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023136194A Division JP7628333B2 (ja) | 2015-11-03 | 2023-08-24 | ヒト患者における自己抗原に対するワクチン接種法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532782A JP2018532782A (ja) | 2018-11-08 |
| JP2018532782A5 true JP2018532782A5 (enExample) | 2019-11-14 |
| JP7378931B2 JP7378931B2 (ja) | 2023-11-14 |
Family
ID=54396782
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541534A Active JP7378931B2 (ja) | 2015-11-03 | 2016-11-02 | ヒト患者における自己抗原に対するワクチン接種法 |
| JP2023136194A Active JP7628333B2 (ja) | 2015-11-03 | 2023-08-24 | ヒト患者における自己抗原に対するワクチン接種法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023136194A Active JP7628333B2 (ja) | 2015-11-03 | 2023-08-24 | ヒト患者における自己抗原に対するワクチン接種法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12290553B2 (enExample) |
| EP (1) | EP3370761A1 (enExample) |
| JP (2) | JP7378931B2 (enExample) |
| KR (1) | KR102857456B1 (enExample) |
| CN (1) | CN108472344A (enExample) |
| AU (1) | AU2016348610B2 (enExample) |
| BR (1) | BR112018008697A2 (enExample) |
| CA (1) | CA3003943A1 (enExample) |
| RU (1) | RU2734924C2 (enExample) |
| WO (1) | WO2017076873A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3370761A1 (en) * | 2015-11-03 | 2018-09-12 | Affiris AG | Method for vaccination against a self-antigen in a human patient |
| AR111760A1 (es) * | 2017-05-19 | 2019-08-14 | Novartis Ag | Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral |
| WO2019222840A1 (en) * | 2018-05-22 | 2019-11-28 | The Governors Of The University Of Alberta | Innocuous, structured scaffolds for structure-based amyloid disease vaccines and antigens |
| CA3185563A1 (en) | 2020-08-04 | 2022-02-10 | Dorian WINTER | Immunogenic compounds |
| KR102527616B1 (ko) | 2021-03-18 | 2023-05-02 | 정성욱 | 항체 관련 정보를 제공하는 방법 및 디바이스 |
| KR20240147981A (ko) | 2022-02-09 | 2024-10-10 | 에이씨 이뮨 에스에이 | 항-알파시누클레인 치료 백신 |
| WO2025172592A1 (en) | 2024-02-15 | 2025-08-21 | Ac Immune Sa | Alpha synuclein therapeutic vaccine |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100333791C (zh) | 2002-10-23 | 2007-08-29 | 葛兰素史密丝克莱恩生物有限公司 | 抗疟疾的疫苗接种方法 |
| AT413945B (de) | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| AT413946B (de) | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| AT506535B1 (de) * | 2008-02-22 | 2010-04-15 | Affiris Forschungs & Entwicklungs Gmbh | Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden |
| AT508569A1 (de) | 2009-07-23 | 2011-02-15 | Affiris Ag | Pharmaceutical compound |
| AT508638B1 (de) | 2009-08-21 | 2011-08-15 | Affiris Ag | Verwendung von peptiden und polypeptiden zur behandlung und/oder prävention von synukleinopathien |
| ES2670576T3 (es) | 2009-09-03 | 2018-05-31 | Pfizer Vaccines Llc | Vacuna de PCSK9 |
| SG181712A1 (en) | 2009-12-15 | 2012-07-30 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| EP2659907A1 (en) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
| EP2666785A1 (en) | 2012-05-23 | 2013-11-27 | Affiris AG | Complement component C5a-based vaccine |
| EP2703483A1 (en) * | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
| CN106459209B (zh) | 2014-02-28 | 2019-10-11 | 阿费里斯股份公司 | Pcsk9疫苗 |
| EP3370761A1 (en) * | 2015-11-03 | 2018-09-12 | Affiris AG | Method for vaccination against a self-antigen in a human patient |
-
2016
- 2016-11-02 EP EP16793798.6A patent/EP3370761A1/en active Pending
- 2016-11-02 RU RU2018120009A patent/RU2734924C2/ru active
- 2016-11-02 BR BR112018008697-5A patent/BR112018008697A2/en active Search and Examination
- 2016-11-02 JP JP2018541534A patent/JP7378931B2/ja active Active
- 2016-11-02 KR KR1020187015512A patent/KR102857456B1/ko active Active
- 2016-11-02 WO PCT/EP2016/076372 patent/WO2017076873A1/en not_active Ceased
- 2016-11-02 AU AU2016348610A patent/AU2016348610B2/en active Active
- 2016-11-02 CA CA3003943A patent/CA3003943A1/en active Pending
- 2016-11-02 CN CN201680064233.5A patent/CN108472344A/zh active Pending
- 2016-11-02 US US15/772,572 patent/US12290553B2/en active Active
-
2023
- 2023-08-24 JP JP2023136194A patent/JP7628333B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018532782A5 (enExample) | ||
| RU2018120009A (ru) | Способ вакцинации против аутоантигена у пациента-человека | |
| JP2023175708A5 (enExample) | ||
| MX2021001762A (es) | Metodo y composicion para estimular la respuesta inmunitaria. | |
| RU2007145052A (ru) | Композиции пептидного конъюгата и способы для профилактики и лечения болезни альцгеймера | |
| JP2012506411A5 (enExample) | ||
| JP2015533376A5 (enExample) | ||
| US20150093432A1 (en) | Composition | |
| US20150093431A1 (en) | Compositions | |
| TW201345927A (zh) | 組成物 | |
| RU2015100889A (ru) | Вакцины для менингококка серогруппы х | |
| JP2015529677A5 (enExample) | ||
| JP2017511327A5 (enExample) | ||
| US20200016249A1 (en) | Il-23-p19 vaccines | |
| JP7754490B2 (ja) | アジュバント組成物 | |
| Otero | ANTIMICROBIAL PEPTIDES FROM MARINE INVERTEBRATES AS ADJUVANTS. | |
| RU2010133432A (ru) | Устранение иммунологической толерантности с использованием генетически кодируемой неприродной аминокислоты | |
| RU2019123453A (ru) | Пептидная вакцина для предупреждения и иммунотерапии деменции альцгеймеровского типа | |
| WO2008100142A3 (en) | Vaccine formulation |