JP2018530557A5 - - Google Patents

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Publication number
JP2018530557A5
JP2018530557A5 JP2018517362A JP2018517362A JP2018530557A5 JP 2018530557 A5 JP2018530557 A5 JP 2018530557A5 JP 2018517362 A JP2018517362 A JP 2018517362A JP 2018517362 A JP2018517362 A JP 2018517362A JP 2018530557 A5 JP2018530557 A5 JP 2018530557A5
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JP
Japan
Prior art keywords
pyrazolo
pyridine
carboxylic acid
phenyl
cyclobutyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018517362A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018530557A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2016/056028 external-priority patent/WO2017060873A1/en
Publication of JP2018530557A publication Critical patent/JP2018530557A/ja
Publication of JP2018530557A5 publication Critical patent/JP2018530557A5/ja
Pending legal-status Critical Current

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JP2018517362A 2015-10-09 2016-10-07 置換ピラゾロ[3,4−b]ピリジン−6−カルボン酸およびこの使用 Pending JP2018530557A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562239475P 2015-10-09 2015-10-09
US62/239,475 2015-10-09
PCT/IB2016/056028 WO2017060873A1 (en) 2015-10-09 2016-10-07 Substituted pyrazolo[3,4-b]pyridin-6-carboxylic acids and their use

Publications (2)

Publication Number Publication Date
JP2018530557A JP2018530557A (ja) 2018-10-18
JP2018530557A5 true JP2018530557A5 (pt-PT) 2019-11-14

Family

ID=57200057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018517362A Pending JP2018530557A (ja) 2015-10-09 2016-10-07 置換ピラゾロ[3,4−b]ピリジン−6−カルボン酸およびこの使用

Country Status (10)

Country Link
US (1) US9796711B2 (pt-PT)
EP (1) EP3359539A1 (pt-PT)
JP (1) JP2018530557A (pt-PT)
CN (1) CN108431002A (pt-PT)
AU (1) AU2016333855A1 (pt-PT)
BR (1) BR112018007145A2 (pt-PT)
CA (1) CA3001094A1 (pt-PT)
MX (1) MX2018004364A (pt-PT)
TW (1) TW201735769A (pt-PT)
WO (1) WO2017060873A1 (pt-PT)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
US10138227B2 (en) 2016-06-03 2018-11-27 Abbvie S.Á.R.L. Heteroaryl substituted pyridines and methods of use
US10399940B2 (en) 2016-10-07 2019-09-03 Abbvie S.Á.R.L. Substituted pyrrolidines and methods of use
US9981910B2 (en) 2016-10-07 2018-05-29 Abbvie S.Á.R.L. Substituted pyrrolidines and methods of use
US20200123137A1 (en) 2016-12-20 2020-04-23 AbbVie S.à.r.l. Deuterated cftr modulators and methods of use
TW201831471A (zh) 2017-02-24 2018-09-01 盧森堡商艾伯維公司 囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法
WO2019193062A1 (en) 2018-04-03 2019-10-10 Abbvie S.Á.R.L Substituted pyrrolidines and their use
WO2020048826A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 5-substituted 1-oxa-3,9-diazaspiro[5.5]undecan-2-one compounds
WO2020048828A1 (en) 2018-09-03 2020-03-12 Bayer Pharma Aktiengesellschaft 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds
WO2020048827A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds
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US11345691B2 (en) 2019-06-03 2022-05-31 AbbVie Global Enterprises Ltd. Prodrug modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
WO2021011327A1 (en) 2019-07-12 2021-01-21 Orphomed, Inc. Compound for treating cystic fibrosis
EP4274828A1 (en) 2021-01-06 2023-11-15 AbbVie Global Enterprises Ltd. Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
WO2022150173A1 (en) 2021-01-06 2022-07-14 AbbVie Global Enterprises Ltd. Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
WO2023151560A1 (en) * 2022-02-08 2023-08-17 Etern Biopharma (Shanghai) Co., Ltd. Bicyclic heteroaryl compounds and uses thereof

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FR2861304B1 (fr) * 2003-10-23 2008-07-18 Univ Grenoble 1 Modulateurs des canaux cftr
AU2005251745A1 (en) 2004-06-04 2005-12-22 The Regents Of The University Of California Compounds having activity in increasing ion transport by mutant-CFTR and uses thereof
CA2810655C (en) 2004-06-24 2013-12-10 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
US8362031B2 (en) * 2004-08-20 2013-01-29 University Of Kansas Lonidamine analogues and treatment of polycystic kidney disease
BRPI0708615A2 (pt) * 2006-03-07 2011-06-07 Array Biopharma Inc compostos de pirazol heterobicìclicos e métodos de uso
CN101687883B (zh) 2007-05-25 2012-05-23 沃泰克斯药物股份有限公司 囊性纤维化跨膜传导调节因子的调节剂
PT2444120T (pt) 2007-12-10 2018-01-03 Novartis Ag Análogos da amilorida espirocíclicos como bloqueadores de enac
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