JP2018528182A5 - - Google Patents
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- JP2018528182A5 JP2018528182A5 JP2018505739A JP2018505739A JP2018528182A5 JP 2018528182 A5 JP2018528182 A5 JP 2018528182A5 JP 2018505739 A JP2018505739 A JP 2018505739A JP 2018505739 A JP2018505739 A JP 2018505739A JP 2018528182 A5 JP2018528182 A5 JP 2018528182A5
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- Japan
- Prior art keywords
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- DYLUUSLLRIQKOE-UHFFFAOYSA-N CC(C)(CNc1nc(Nc2ccnc(C(F)(F)F)c2)nc(-c2cccc(C(F)(F)F)n2)n1)O Chemical compound CC(C)(CNc1nc(Nc2ccnc(C(F)(F)F)c2)nc(-c2cccc(C(F)(F)F)n2)n1)O DYLUUSLLRIQKOE-UHFFFAOYSA-N 0.000 description 1
- LYNBZRJTRHTSKI-UHFFFAOYSA-N Nc1ccnc(C(F)(F)F)c1 Chemical compound Nc1ccnc(C(F)(F)F)c1 LYNBZRJTRHTSKI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562201546P | 2015-08-05 | 2015-08-05 | |
| US62/201,546 | 2015-08-05 | ||
| PCT/US2016/045553 WO2017024134A1 (en) | 2015-08-05 | 2016-08-04 | Methods of preparing 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diols and 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diamines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213670A Division JP2021063097A (ja) | 2015-08-05 | 2020-12-23 | ６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジオール及び６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジアミンを調製する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528182A JP2018528182A (ja) | 2018-09-27 |
| JP2018528182A5 true JP2018528182A5 (cg-RX-API-DMAC7.html) | 2019-09-19 |
| JP6816106B2 JP6816106B2 (ja) | 2021-01-20 |
Family
ID=56684781
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505739A Active JP6816106B2 (ja) | 2015-08-05 | 2016-08-04 | ６−ピリジル−１，３，５−トリアジン−２，４−ジオール及び６−ピリジル−１，３，５−トリアジン−２，４−ジアミンを調製する方法 |
| JP2020213670A Pending JP2021063097A (ja) | 2015-08-05 | 2020-12-23 | ６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジオール及び６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジアミンを調製する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213670A Pending JP2021063097A (ja) | 2015-08-05 | 2020-12-23 | ６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジオール及び６−（アリールまたはヘテロアリール）−１，３，５−トリアジン−２，４−ジアミンを調製する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9751863B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3331866B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6816106B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN108349933A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2016303614A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2993615A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX365590B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017024134A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017529382A (ja) | 2014-09-29 | 2017-10-05 | アギオス ファーマシューティカルス，インコーポレーテッド | 治療活性を有する化合物及びその使用方法 |
| JP7220986B6 (ja) | 2015-02-04 | 2024-02-08 | アジオス ファーマシューティカルズ， インコーポレイテッド | 治療効果のある化合物及びその使用方法 |
| US9751863B2 (en) * | 2015-08-05 | 2017-09-05 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| KR20180063125A (ko) | 2015-10-15 | 2018-06-11 | 아지오스 파마슈티컬스 아이엔씨. | 악성종양을 치료하기 위한 복합 요법 |
| US10695352B2 (en) | 2015-10-15 | 2020-06-30 | Celgene Corporation | Combination therapy for treating malignancies |
| ES2905915T3 (es) | 2015-12-04 | 2022-04-12 | Servier Lab | Procedimientos de tratamiento de neoplasias malignas |
| MA43640A (fr) | 2016-02-26 | 2018-11-28 | Agios Pharmaceuticals Inc | Inhibiteurs de idh1 pour le traitement de cancers hématologiques et de tumeurs solides |
| MX392941B (es) | 2016-09-07 | 2025-03-24 | Celgene Corp | Composiciones para comprimidos. |
| WO2018204787A1 (en) | 2017-05-05 | 2018-11-08 | Memorial Sloan Kettering Cancer Center | Methods of treatment of myeloproliferative neoplasm |
| US20220017490A1 (en) | 2018-11-02 | 2022-01-20 | Celgene Corporation | Co-crystals of 2-methyl-1 -[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl) pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol, compositions and methods of use thereof |
| WO2020092894A1 (en) | 2018-11-02 | 2020-05-07 | Celgene Corporation | Solid forms of 2-methyl-1-[(4-[6-(trifluoromethyl) pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl) amino]propan-2-ol |
| US20220017489A1 (en) | 2018-11-02 | 2022-01-20 | Celgene Corporation | Solid dispersions for treatment of cancer |
| JP2023503842A (ja) | 2019-11-14 | 2023-02-01 | セルジーン コーポレーション | がんを処置するための小児用製剤 |
| CN111592524B (zh) * | 2020-05-20 | 2023-11-17 | 温州市天聚万迅信息科技有限公司 | 恩西德尼的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2390529A (en) | 1942-02-03 | 1945-12-11 | Ernst A H Friedheim | Hydrazino-1,3,5-triazino derivatives of substituted phenylarsenic compounds |
| JPS5170779A (ja) * | 1974-12-17 | 1976-06-18 | Nippon Shinyaku Co Ltd | Shinkinaguanamidoruino seiho |
| JPS58186682A (ja) | 1982-04-27 | 1983-10-31 | 日本化薬株式会社 | セルロ−ス又はセルロ−ス含有繊維材料の染色法 |
| DE3512630A1 (de) | 1985-04-06 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Verfahren zum faerben oder bedrucken von cellulosefasern oder cellulosemischfasern |
| DE59106971D1 (de) | 1990-07-12 | 1996-01-11 | Ciba Geigy Ag | Verfahren zur photochemischen und thermischen Stabilisierung von Polyamid-Fasermaterialien. |
| JPH11158073A (ja) | 1997-09-26 | 1999-06-15 | Takeda Chem Ind Ltd | アデノシンａ３拮抗剤 |
| AU5379900A (en) | 1999-06-07 | 2000-12-28 | Shire Biochem Inc. | Thiophene integrin inhibitors |
| EP2256108B1 (en) | 2002-07-18 | 2016-03-23 | Janssen Pharmaceutica NV | Substituted triazine kinase inhibitors |
| JP5450381B2 (ja) | 2007-04-30 | 2014-03-26 | プロメティック・バイオサイエンスィズ・インコーポレーテッド | 化合物、そのような化合物を含有する組成物、及びそのような化合物を用いるがん及び自己免疫疾患の治療法 |
| GB0805477D0 (en) | 2008-03-26 | 2008-04-30 | Univ Nottingham | Pyrimidines triazines and their use as pharmaceutical agents |
| WO2010144338A1 (en) | 2009-06-08 | 2010-12-16 | Abraxis Bioscience, Llc | Triazine derivatives and their therapeutical applications |
| PE20142098A1 (es) * | 2012-01-06 | 2015-01-08 | Agios Pharmaceuticals Inc | Compuestos terapeuticamente activos y sus metodos de uso |
| KR20140131955A (ko) | 2012-03-09 | 2014-11-14 | 카나 바이오사이언스 인코포레이션 | 신규 트리아진 유도체 |
| WO2015003360A2 (en) * | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| AU2014287122B9 (en) | 2013-07-11 | 2018-11-01 | Les Laboratoires Servier | N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment of cancer |
| AU2014295938B2 (en) | 2013-08-02 | 2018-07-19 | Les Laboratoires Servier | Therapeutically active compounds and their methods of use |
| JP2017529382A (ja) | 2014-09-29 | 2017-10-05 | アギオス ファーマシューティカルス，インコーポレーテッド | 治療活性を有する化合物及びその使用方法 |
| JP7220986B6 (ja) | 2015-02-04 | 2024-02-08 | アジオス ファーマシューティカルズ， インコーポレイテッド | 治療効果のある化合物及びその使用方法 |
| US9751863B2 (en) * | 2015-08-05 | 2017-09-05 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
-
2016
- 2016-08-04 US US15/229,011 patent/US9751863B2/en active Active
- 2016-08-04 CN CN201680045391.6A patent/CN108349933A/zh active Pending
- 2016-08-04 WO PCT/US2016/045553 patent/WO2017024134A1/en not_active Ceased
- 2016-08-04 AU AU2016303614A patent/AU2016303614A1/en not_active Abandoned
- 2016-08-04 CA CA2993615A patent/CA2993615A1/en not_active Abandoned
- 2016-08-04 JP JP2018505739A patent/JP6816106B2/ja active Active
- 2016-08-04 MX MX2018001424A patent/MX365590B/es active IP Right Grant
- 2016-08-04 EP EP16751449.6A patent/EP3331866B1/en active Active
-
2020
- 2020-12-23 JP JP2020213670A patent/JP2021063097A/ja active Pending
-
2021
- 2021-01-27 AU AU2021200494A patent/AU2021200494A1/en not_active Abandoned
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