JP2018526416A5 - - Google Patents

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Publication number
JP2018526416A5
JP2018526416A5 JP2018512944A JP2018512944A JP2018526416A5 JP 2018526416 A5 JP2018526416 A5 JP 2018526416A5 JP 2018512944 A JP2018512944 A JP 2018512944A JP 2018512944 A JP2018512944 A JP 2018512944A JP 2018526416 A5 JP2018526416 A5 JP 2018526416A5
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JP
Japan
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compound according
hydrogen
alkyl
aryl
haloalkyl
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JP2018512944A
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English (en)
Japanese (ja)
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JP2018526416A (ja
JP6966425B2 (ja
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Priority claimed from PCT/US2016/050685 external-priority patent/WO2017044567A1/en
Publication of JP2018526416A publication Critical patent/JP2018526416A/ja
Publication of JP2018526416A5 publication Critical patent/JP2018526416A5/ja
Application granted granted Critical
Publication of JP6966425B2 publication Critical patent/JP6966425B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018512944A 2015-09-09 2016-09-08 抗がん剤としての複素環式の限定された三環系スルホンアミド Expired - Fee Related JP6966425B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562216168P 2015-09-09 2015-09-09
US62/216,168 2015-09-09
PCT/US2016/050685 WO2017044567A1 (en) 2015-09-09 2016-09-08 Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents

Publications (3)

Publication Number Publication Date
JP2018526416A JP2018526416A (ja) 2018-09-13
JP2018526416A5 true JP2018526416A5 (OSRAM) 2019-11-07
JP6966425B2 JP6966425B2 (ja) 2021-11-17

Family

ID=56940436

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018512944A Expired - Fee Related JP6966425B2 (ja) 2015-09-09 2016-09-08 抗がん剤としての複素環式の限定された三環系スルホンアミド

Country Status (6)

Country Link
US (1) US10221158B2 (OSRAM)
EP (1) EP3347350A1 (OSRAM)
JP (1) JP6966425B2 (OSRAM)
CN (1) CN108349943A (OSRAM)
CA (1) CA2997769A1 (OSRAM)
WO (1) WO2017044567A1 (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138500A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents
US9937180B2 (en) 2014-03-11 2018-04-10 Icahn School Of Medicine At Mount Sinai Constrained tricyclic sulfonamides
JP6955485B2 (ja) 2015-09-09 2021-10-27 アイカーン スクール オブ メディスン アット マウント サイナイＩｃａｈｎ Ｓｃｈｏｏｌ ｏｆ Ｍｅｄｉｃｉｎｅ ａｔ Ｍｔ． Ｓｉｎａｉ 抗がん剤としての複素環式の限定された三環系スルホンアミド
WO2021150695A1 (en) * 2020-01-22 2021-07-29 Icahn School Of Medicine At Mount Sinai Constrained n-substituted tetrahydrobenzoazepine sulfonamides as anticancer and neuroprotective agents
WO2021170913A1 (en) * 2020-02-28 2021-09-02 Rappta Therapeutics Oy Tricyclic modulators of pp2a
WO2021188949A1 (en) * 2020-03-20 2021-09-23 Atux Iskay Llc 3-diarylmethylenes and uses thereof
CN114272378B (zh) * 2020-09-27 2023-06-23 四川大学华西医院 一种使cttnbp2nl功能缺失的试剂在制备治疗疾病的药物中的用途
AU2022216880A1 (en) * 2021-02-08 2023-08-10 Rappta Therapeutics Oy Substituted cyclic modulators of protein phosphatase 2a (pp2a) and methods using same
CN118119607A (zh) * 2021-08-18 2024-05-31 阿图什伊斯卡伊有限责任公司 作为抗癌、抗炎、抗纤维和神经保护剂的2-二芳基甲基-4-氨基四氢吡喃衍生物及相关化合物
KR20250057795A (ko) * 2022-08-04 2025-04-29 랍타 테라퓨틱스 오와이 단백질 포스파타제 2a(pp2a) 조절제로서 사용하기 위한 방향족 화합물

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ATE225334T1 (de) 1993-07-26 2002-10-15 Eisai Co Ltd Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring
WO1997030038A1 (en) 1996-02-15 1997-08-21 Mitsubishi Chemical Corporation Diarylsultam derivatives
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MX2015010407A (es) * 2013-02-19 2015-10-26 Icahn School Med Mount Sinai Heterociclos triciclicos como agentes anticancer.
WO2015138500A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents
US9937180B2 (en) 2014-03-11 2018-04-10 Icahn School Of Medicine At Mount Sinai Constrained tricyclic sulfonamides
CA2994830A1 (en) 2015-08-06 2017-02-09 Icahn School Of Medicine At Mount Sinai Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols
JP6955485B2 (ja) 2015-09-09 2021-10-27 アイカーン スクール オブ メディスン アット マウント サイナイＩｃａｈｎ Ｓｃｈｏｏｌ ｏｆ Ｍｅｄｉｃｉｎｅ ａｔ Ｍｔ． Ｓｉｎａｉ 抗がん剤としての複素環式の限定された三環系スルホンアミド
WO2017044571A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Tricyclic sultam sulfonamides as anticancer and neuroprotective agents
WO2017044572A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Ring constrained diarylamino sulfonamides as anti-cancer agents
WO2017044575A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Constrained benzhydryl sulfonamides as anticancer and neuroprotective agents

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