JP2018526325A5 - - Google Patents
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- Publication number
- JP2018526325A5 JP2018526325A5 JP2017563568A JP2017563568A JP2018526325A5 JP 2018526325 A5 JP2018526325 A5 JP 2018526325A5 JP 2017563568 A JP2017563568 A JP 2017563568A JP 2017563568 A JP2017563568 A JP 2017563568A JP 2018526325 A5 JP2018526325 A5 JP 2018526325A5
- Authority
- JP
- Japan
- Prior art keywords
- topical pharmaceutical
- pharmaceutical composition
- concentration
- weight
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 12
- OGQICQVSFDPSEI-UHFFFAOYSA-N Zorac Chemical compound N1=CC(C(=O)OCC)=CC=C1C#CC1=CC=C(SCCC2(C)C)C2=C1 OGQICQVSFDPSEI-UHFFFAOYSA-N 0.000 claims description 4
- 229960000565 tazarotene Drugs 0.000 claims description 4
- 201000004681 Psoriasis Diseases 0.000 claims description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 12
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 4
- 229920002125 Sokalan® Polymers 0.000 claims 4
- 229960001631 carbomer Drugs 0.000 claims 4
- 239000000839 emulsion Substances 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 4
- -1 dicarboxylic acid ester Chemical class 0.000 claims 3
- 229950008396 ulobetasol propionate Drugs 0.000 claims 3
- BDSYKGHYMJNPAB-LICBFIPMSA-N ulobetasol propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]2(C)C[C@@H]1O BDSYKGHYMJNPAB-LICBFIPMSA-N 0.000 claims 3
- 229920001519 homopolymer Polymers 0.000 claims 2
- 239000007764 o/w emulsion Substances 0.000 claims 2
- KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 claims 2
- 239000008346 aqueous phase Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 150000001990 dicarboxylic acid derivatives Chemical class 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 description 2
- 229940115747 halobetasol Drugs 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- IQIBKLWBVJPOQO-UHFFFAOYSA-N tazarotenic acid Chemical class C1=C2C(C)(C)CCSC2=CC=C1C#CC1=CC=C(C(O)=O)C=N1 IQIBKLWBVJPOQO-UHFFFAOYSA-N 0.000 description 1
- LEHFPXVYPMWYQD-XHIJKXOTSA-N ulobetasol Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]2(C)C[C@@H]1O LEHFPXVYPMWYQD-XHIJKXOTSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562181481P | 2015-06-18 | 2015-06-18 | |
| US62/181,481 | 2015-06-18 | ||
| PCT/US2016/035991 WO2016205001A1 (en) | 2015-06-18 | 2016-06-06 | Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018526325A JP2018526325A (ja) | 2018-09-13 |
| JP2018526325A5 true JP2018526325A5 (https=) | 2019-07-11 |
| JP6997624B2 JP6997624B2 (ja) | 2022-01-17 |
Family
ID=56131662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563568A Active JP6997624B2 (ja) | 2015-06-18 | 2016-06-06 | 乾癬を治療するためのコルチコステロイドおよびレチノイドを含む局所用組成物 |
Country Status (20)
| Country | Link |
|---|---|
| US (7) | US10251895B2 (https=) |
| EP (1) | EP3310389B1 (https=) |
| JP (1) | JP6997624B2 (https=) |
| KR (2) | KR102643849B1 (https=) |
| CN (1) | CN108282998B (https=) |
| AU (1) | AU2016279801B2 (https=) |
| BR (1) | BR112017027332B1 (https=) |
| CA (1) | CA2988577A1 (https=) |
| CY (1) | CY1123354T1 (https=) |
| DK (1) | DK3310389T3 (https=) |
| ES (1) | ES2812451T3 (https=) |
| HR (1) | HRP20201250T1 (https=) |
| HU (1) | HUE050603T2 (https=) |
| LT (1) | LT3310389T (https=) |
| MX (1) | MX377544B (https=) |
| PL (1) | PL3310389T3 (https=) |
| PT (1) | PT3310389T (https=) |
| RS (1) | RS60672B1 (https=) |
| SI (1) | SI3310389T1 (https=) |
| WO (1) | WO2016205001A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11957753B2 (en) | 2010-11-22 | 2024-04-16 | Bausch Health Ireland Limited | Pharmaceutical formulations containing corticosteroids for topical administration |
| CN108282998B (zh) * | 2015-06-18 | 2021-07-06 | 凡利亚药品北美公司 | 用于治疗银屑病的包含皮质类固醇和类视黄醇的局部组合物 |
| MX2018000421A (es) * | 2015-07-13 | 2018-05-17 | Dr Reddy´S Laboratories Ltd | Composiciones de retinoides topicos. |
| WO2018209262A1 (en) * | 2017-05-12 | 2018-11-15 | Valeant Pharmaceuticals North America | Topical compositions and methods for treating skin diseases |
| US11311482B2 (en) * | 2017-05-12 | 2022-04-26 | Bausch Health Us, Llc | Topical compositions and methods for treating skin diseases |
| PL3641728T3 (pl) * | 2017-06-23 | 2021-09-20 | Laboratorios Salvat, S.A. | Kompozycja klobetazolu w postaci nanoemulsji typu olej w wodzie |
| US11364198B2 (en) * | 2018-04-05 | 2022-06-21 | Bausch Health Ireland Limited | Polymeric emulsion delivery systems |
| US10653656B2 (en) * | 2018-04-05 | 2020-05-19 | Bausch Health Ireland Limited | Topical pharmaceutical compositions for treating skin conditions |
| EP3937905A4 (en) * | 2019-03-14 | 2022-12-28 | Crescita Therapeutics Inc. | RINSING COMPOSITIONS AND THEIR USES FOR THE ADMINISTRATION OF ACTIVE AGENTS |
| KR102327827B1 (ko) | 2019-11-01 | 2021-11-18 | 한국과학기술연구원 | 강황 추출물을 유효성분으로 포함하고 자외선 처리를 포함하는 건선 개선용 조성물 |
| CN113116891B (zh) * | 2019-12-30 | 2024-07-16 | 重庆华邦制药有限公司 | 一种乳膏及其制备方法 |
| KR102451304B1 (ko) | 2020-09-14 | 2022-10-07 | 한국과학기술연구원 | 꿩의다리속 추출물을 유효성분으로 포함하는 건선 개선용 조성물 |
| KR102527907B1 (ko) | 2020-09-14 | 2023-05-03 | 한국과학기술연구원 | 무산상자 추출물을 유효성분으로 포함하는 건선 개선용 조성물 |
| KR102461001B1 (ko) | 2020-09-14 | 2022-11-01 | 한국과학기술연구원 | 술패랭이꽃 추출물을 유효성분으로 포함하는 건선 개선용 조성물 |
| KR102769642B1 (ko) | 2021-09-17 | 2025-02-20 | 한국과학기술연구원 | 눈개승마 추출물을 유효성분으로 포함하는 건선 개선용 조성물 |
| KR102692893B1 (ko) | 2021-09-17 | 2024-08-08 | 한국과학기술연구원 | 시미시푸고라이드 에이를 유효성분으로 포함하는 건선 개선용 조성물 |
| CN113975249B (zh) * | 2021-10-14 | 2023-01-03 | 中山大学·深圳 | Tris-BNP纳米颗粒的制备及其在皮肤疾病治疗中的应用 |
| CN113712918A (zh) * | 2021-10-28 | 2021-11-30 | 济南纽华医药科技有限公司 | 一种阿普斯特微乳及其制备方法 |
| WO2024141639A1 (en) * | 2022-12-31 | 2024-07-04 | Bausch Health Ireland Limited | Use of a fixed combination of halobetasol propionate and tazarotene to treat conditions mediated by interleukin-17a |
| WO2024201481A1 (en) * | 2023-03-29 | 2024-10-03 | Scires Technologies Private Limited | Anti-psoriasis topical formulation containing combination drugs and method of preparation thereof |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU75903A1 (https=) | 1976-09-29 | 1978-05-16 | ||
| NL7105591A (en) | 1971-04-24 | 1972-10-26 | Topical antiphlogistic compsns - contng 3, 20-diketo-9 alpha, 11 beta-dichloro - 16 alpha, 17 alpha-dimethyl-21-hydroxy pregna-1,4- | |
| DE2655570A1 (de) | 1975-12-12 | 1977-06-16 | Ciba Geigy Ag | Neue polyhalogensteroide und verfahren zu ihrer herstellung |
| US4048310A (en) | 1976-02-24 | 1977-09-13 | E. R. Squibb & Sons, Inc. | Topical steroid formulation in form of lotion or cream |
| US4083974A (en) | 1977-03-07 | 1978-04-11 | The Upjohn Company | Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether |
| JPS5850964B2 (ja) | 1978-03-07 | 1983-11-14 | 東興薬品工業株式会社 | ステロイド含有クリ−ム製剤およびその製造方法 |
| US4233295A (en) | 1979-05-31 | 1980-11-11 | E. R. Squibb & Sons, Inc. | Corticosteroid formulations containing sebacate carrier |
| US4299828A (en) | 1979-05-31 | 1981-11-10 | E. R. Squibb & Sons, Inc. | Corticosteroid stick formulations |
| AU5794680A (en) | 1979-05-31 | 1980-12-04 | E.R. Squibb & Sons, Inc. | Corticosteroid stick formulations |
| CH649923A5 (de) | 1980-10-06 | 1985-06-28 | Glaxo Group Ltd | Topisch verabreichbare pharmazeutische zusammensetzungen, enthaltend anti-inflammatorische steroide. |
| JPS58225009A (ja) | 1982-06-23 | 1983-12-27 | Shionogi & Co Ltd | コルチコステロイド外用製剤 |
| DE3225848A1 (de) | 1982-07-07 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Kortikoidhaltige zubereitung zur topischen applikation |
| GB8401965D0 (en) | 1984-01-25 | 1984-02-29 | Beecham Group Plc | Composition |
| CA1303991C (en) | 1986-03-31 | 1992-06-23 | Chung H. Cheng | Composition and method for delivering a steroid active ingredient |
| US5019569A (en) | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
| JPH0676328B2 (ja) | 1987-04-14 | 1994-09-28 | 株式会社大塚製薬工場 | ステロイドクリ−ム製剤 |
| JPH0676327B2 (ja) | 1987-04-14 | 1994-09-28 | 株式会社大塚製薬工場 | ステロイド軟膏製剤 |
| JPH07116026B2 (ja) | 1987-07-07 | 1995-12-13 | 株式会社資生堂 | ジクロフェナックナトリウム含有乳化外用剤 |
| WO1991008733A1 (en) | 1989-12-20 | 1991-06-27 | Schering Corporation | Stable cream and lotion bases for lipophilic drug compositions |
| KR0168436B1 (ko) | 1990-03-02 | 1999-01-15 | 후쿠하라 요시하루 | 비스테로이드계 소염진통제를 함유하는 수중유형 유화 조성물 |
| TW218849B (https=) * | 1991-05-17 | 1994-01-11 | Bristol Myers Squibb Co | |
| US5326566A (en) | 1991-05-17 | 1994-07-05 | Bristol-Myers Squibb Company | Use of dibutyl adipate and isopropyl myristate in topical and transdermal products |
| CA2282682C (en) * | 1997-02-20 | 2008-08-19 | Allergan Sales, Inc. | Tazarotene and corticosteroid treatment for psoriasis |
| SE9800729L (sv) | 1998-03-06 | 1999-09-07 | Scotia Lipidteknik Ab | Ny topikal formulering I |
| GB9823036D0 (en) | 1998-10-22 | 1998-12-16 | Glaxo Group Ltd | Fluticasone lotion having improved vasoconstrictor activity |
| AU2877800A (en) * | 1999-02-12 | 2000-08-29 | Susan Bershad | Short contact treatment of psoriasis with topical retinoids |
| US6730308B1 (en) * | 1999-03-08 | 2004-05-04 | Allergan, Inc. | Tazarotene and alpha hydroxy acid treatment for psoriasis and/or photodamage |
| US6656928B1 (en) | 1999-09-02 | 2003-12-02 | Mccadden Michael E. | Composition for the topical treatment of rashes, dermatoses and lesions |
| US6479058B1 (en) | 1999-09-02 | 2002-11-12 | Mccadden Michael E. | Composition for the topical treatment of poison ivy and other forms of contact dermatitis |
| US6387383B1 (en) | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
| BRPI0114927B8 (pt) * | 2000-10-27 | 2021-05-25 | Leo Pharma As | composição de gel farmacêutica não aquosa para aplicação na pele, e, uso de uma composição |
| US6709663B2 (en) | 2001-08-31 | 2004-03-23 | Healthpoint, Ltd. | Multivesicular emulsion drug delivery systems |
| US6765001B2 (en) | 2001-12-21 | 2004-07-20 | Medicis Pharmaceutical Corporation | Compositions and methods for enhancing corticosteroid delivery |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US7544674B2 (en) | 2002-10-25 | 2009-06-09 | Galderma S.A. | Topical skin care composition |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| CN1210034C (zh) * | 2002-12-06 | 2005-07-13 | 重庆华邦制药股份有限公司 | 治疗银屑病的药物组合物 |
| AU2003302305A1 (en) | 2002-12-31 | 2004-07-22 | Sachin S Bhagwat | Benzoquinolizine-2-carboxylic acid-containing compositions |
| JP2004359585A (ja) | 2003-06-03 | 2004-12-24 | Medorekkusu:Kk | 被膜形成型の副腎皮質ステロイド薬含有外用製剤 |
| CN1210035C (zh) * | 2003-09-29 | 2005-07-13 | 中国医学科学院皮肤病研究所 | 治疗银屑病的复方外用药物 |
| CN1210041C (zh) * | 2003-09-29 | 2005-07-13 | 中国医学科学院皮肤病研究所 | 治疗痤疮的复方外用药物 |
| US8741333B2 (en) | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
| JPWO2006098353A1 (ja) | 2005-03-15 | 2008-08-28 | 協和醗酵工業株式会社 | 外用剤 |
| TW200740441A (en) * | 2005-06-17 | 2007-11-01 | Combinatorx Inc | Methods and reagents for the treatment of inflammatory disorders |
| EP1968541A2 (en) | 2005-12-14 | 2008-09-17 | Zars, Inc. | Compositions and methods for dermal delivery of drugs |
| PT2494959E (pt) | 2006-07-05 | 2015-02-20 | Foamix Pharmaceuticals Ltd | Veículo formador de espuma de ácido dicarboxílico e suas composições farmacêuticas |
| AU2007355106A1 (en) | 2006-11-29 | 2008-12-18 | Foamix Ltd. | Foamable waterless compositions with modulating agents |
| RU2470645C2 (ru) | 2007-09-10 | 2012-12-27 | Гленмарк Фармасьютикалс Лимитед | Фармацевтическая композиция для местного применения, содержащая комбинацию фузидовой кислоты и кортикостероида |
| WO2009084020A2 (en) | 2007-10-18 | 2009-07-09 | Glenmark Pharmaceuticals Limited | Topical composition comprising halobetasol and salicylic acid |
| MX379265B (es) | 2008-06-26 | 2025-03-11 | Anterios Inc | Aplicacion dérmica de toxina botulínica en nanoemulsiones para usarse en el tratamiento de trastornos de la piel. |
| CN102438590B (zh) | 2009-02-25 | 2013-07-10 | 施泰福研究澳大利亚有限公司 | 局部泡沫组合物 |
| US20130310355A1 (en) | 2009-12-15 | 2013-11-21 | Young Pharmaceuticals, Inc. | Low toxicity topical active agent delivery system |
| US9782341B2 (en) | 2010-10-15 | 2017-10-10 | John E. Kulesza | Delivery of hydrophobic bioactive agents |
| WO2012061630A2 (en) * | 2010-11-04 | 2012-05-10 | 442 Ventures, Llc | Composition and method for treating skin conditions |
| US8809307B2 (en) * | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| US9034926B2 (en) * | 2010-12-30 | 2015-05-19 | Nicholas V. Perricone | Topical nitrone spin trap compositions for psoriasis |
| TW201311295A (zh) | 2011-06-03 | 2013-03-16 | Allergan Inc | 對皮脂腺之類視色素化合物之目標遞送 |
| SG11201403762PA (en) * | 2012-01-09 | 2014-07-30 | Almirall Sa | Topical pharmaceutical compositions comprising bexarotene and a corticosteroids |
| US8962028B2 (en) | 2012-10-18 | 2015-02-24 | MiCal Pharmaceuticals LLC—H Series, a Series of MiCal Pharmaceuticals LLC, a Multi-Division Limited Liability Company | Topical steroid composition and method |
| CN104288157B (zh) * | 2013-01-29 | 2018-04-13 | 江苏知原药业有限公司 | 包含丙酸氯倍他索和维a酸的固体分散体及其制备方法 |
| CA2925676A1 (en) * | 2013-09-25 | 2015-04-02 | Sun Pharmaceutical Industries Limited | Topical spray composition of halobetasol |
| US20190133943A1 (en) | 2015-06-18 | 2019-05-09 | Valeant Pharmaceuticals North America | Topical compositions and methods for treating skin diseases |
| CN108282998B (zh) * | 2015-06-18 | 2021-07-06 | 凡利亚药品北美公司 | 用于治疗银屑病的包含皮质类固醇和类视黄醇的局部组合物 |
| US11311482B2 (en) * | 2017-05-12 | 2022-04-26 | Bausch Health Us, Llc | Topical compositions and methods for treating skin diseases |
| WO2018209262A1 (en) | 2017-05-12 | 2018-11-15 | Valeant Pharmaceuticals North America | Topical compositions and methods for treating skin diseases |
-
2016
- 2016-06-06 CN CN201680035629.7A patent/CN108282998B/zh active Active
- 2016-06-06 HU HUE16729470A patent/HUE050603T2/hu unknown
- 2016-06-06 EP EP16729470.1A patent/EP3310389B1/en active Active
- 2016-06-06 KR KR1020187001229A patent/KR102643849B1/ko active Active
- 2016-06-06 WO PCT/US2016/035991 patent/WO2016205001A1/en not_active Ceased
- 2016-06-06 SI SI201630936T patent/SI3310389T1/sl unknown
- 2016-06-06 CA CA2988577A patent/CA2988577A1/en active Pending
- 2016-06-06 HR HRP20201250TT patent/HRP20201250T1/hr unknown
- 2016-06-06 US US15/173,961 patent/US10251895B2/en active Active
- 2016-06-06 PT PT167294701T patent/PT3310389T/pt unknown
- 2016-06-06 PL PL16729470T patent/PL3310389T3/pl unknown
- 2016-06-06 DK DK16729470.1T patent/DK3310389T3/da active
- 2016-06-06 BR BR112017027332-2A patent/BR112017027332B1/pt active IP Right Grant
- 2016-06-06 RS RS20200997A patent/RS60672B1/sr unknown
- 2016-06-06 JP JP2017563568A patent/JP6997624B2/ja active Active
- 2016-06-06 AU AU2016279801A patent/AU2016279801B2/en active Active
- 2016-06-06 MX MX2017015990A patent/MX377544B/es active IP Right Grant
- 2016-06-06 LT LTEP16729470.1T patent/LT3310389T/lt unknown
- 2016-06-06 ES ES16729470T patent/ES2812451T3/es active Active
- 2016-06-06 KR KR1020247006984A patent/KR102779108B1/ko active Active
-
2018
- 2018-02-23 US US15/903,785 patent/US10426787B2/en active Active
-
2019
- 2019-04-08 US US16/377,540 patent/US20190231797A1/en not_active Abandoned
-
2020
- 2020-08-04 CY CY20201100719T patent/CY1123354T1/el unknown
-
2021
- 2021-01-21 US US17/154,591 patent/US11679115B2/en active Active
- 2021-07-02 US US17/366,871 patent/US11679116B2/en active Active
-
2022
- 2022-11-23 US US17/993,817 patent/US11648256B2/en active Active
-
2023
- 2023-05-04 US US18/312,162 patent/US20230355640A1/en not_active Abandoned
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