JP2018524019A5 - - Google Patents

Download PDF

Info

Publication number
JP2018524019A5
JP2018524019A5 JP2018515195A JP2018515195A JP2018524019A5 JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5 JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5
Authority
JP
Japan
Prior art keywords
seq
molecular weight
polypeptide
isolated
high molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018515195A
Other languages
English (en)
Japanese (ja)
Other versions
JP6952685B2 (ja
JP2018524019A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/035858 external-priority patent/WO2016197018A1/en
Publication of JP2018524019A publication Critical patent/JP2018524019A/ja
Publication of JP2018524019A5 publication Critical patent/JP2018524019A5/ja
Priority to JP2021158128A priority Critical patent/JP7404320B2/ja
Application granted granted Critical
Publication of JP6952685B2 publication Critical patent/JP6952685B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018515195A 2015-06-05 2016-06-03 線維症の治療において使用するためのエンドスタチン断片およびバリアント Expired - Fee Related JP6952685B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021158128A JP7404320B2 (ja) 2015-06-05 2021-09-28 線維症の治療において使用するためのエンドスタチン断片およびバリアント

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562171889P 2015-06-05 2015-06-05
US62/171,889 2015-06-05
US201562257607P 2015-11-19 2015-11-19
US62/257,607 2015-11-19
PCT/US2016/035858 WO2016197018A1 (en) 2015-06-05 2016-06-03 Endostatin fragments and variants for use in treating fibrosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021158128A Division JP7404320B2 (ja) 2015-06-05 2021-09-28 線維症の治療において使用するためのエンドスタチン断片およびバリアント

Publications (3)

Publication Number Publication Date
JP2018524019A JP2018524019A (ja) 2018-08-30
JP2018524019A5 true JP2018524019A5 (OSRAM) 2019-07-04
JP6952685B2 JP6952685B2 (ja) 2021-10-20

Family

ID=56236074

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018515195A Expired - Fee Related JP6952685B2 (ja) 2015-06-05 2016-06-03 線維症の治療において使用するためのエンドスタチン断片およびバリアント
JP2021158128A Active JP7404320B2 (ja) 2015-06-05 2021-09-28 線維症の治療において使用するためのエンドスタチン断片およびバリアント

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021158128A Active JP7404320B2 (ja) 2015-06-05 2021-09-28 線維症の治療において使用するためのエンドスタチン断片およびバリアント

Country Status (10)

Country Link
US (2) US10844392B2 (OSRAM)
EP (1) EP3303383A1 (OSRAM)
JP (2) JP6952685B2 (OSRAM)
KR (1) KR20180033499A (OSRAM)
CN (2) CN115925878A (OSRAM)
AU (2) AU2016270428B2 (OSRAM)
BR (1) BR112017026209A2 (OSRAM)
CA (1) CA2988299C (OSRAM)
WO (1) WO2016197018A1 (OSRAM)
ZA (1) ZA201708223B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6952685B2 (ja) 2015-06-05 2021-10-20 アイバイオ・インコーポレイテッドIbio, Inc. 線維症の治療において使用するためのエンドスタチン断片およびバリアント
NZ774126A (en) * 2018-09-14 2023-05-26 Akso Biopharmaceutical Inc Spd-1 variant - fc fusion proteins
US20210008173A1 (en) * 2019-07-10 2021-01-14 Musc Foundation For Research Development Endostatin peptides for the treatment of tumors, fibrosis and acute lung injury
CN114364691B (zh) * 2019-07-31 2023-12-12 马克斯·普朗克科学促进学会 作为纤维化基质积累的抑制剂的肽
JP7493945B2 (ja) * 2020-01-28 2024-06-03 ポーラ化成工業株式会社 培養組織の観察方法、培養方法、評価方法及び培養器具
WO2022006601A1 (en) * 2020-07-02 2022-01-06 Northwestern University Human recombinant ace2-fc mutants that decouple anti-sars-cov-2 activity from cardiovascular effects
US20250195673A1 (en) * 2020-11-30 2025-06-19 Fred Hutchinson Cancer Center Compositions and methods for selective depletion of target molecules

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US750375A (en) 1904-01-26 Potato-digger
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3832253A (en) 1973-03-21 1974-08-27 Baxter Laboratories Inc Method of making an inflatable balloon catheter
US4667014A (en) 1983-03-07 1987-05-19 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
US7045313B1 (en) 1982-11-30 2006-05-16 The United States Of America As Represented By The Department Of Health And Human Services Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA
US4452775A (en) 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
IT1164225B (it) 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
CA1200416A (en) 1983-05-13 1986-02-11 Societe Des Produits Nestle S.A. Food process
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5091309A (en) 1986-01-16 1992-02-25 Washington University Sindbis virus vectors
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US5093258A (en) 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
US5217879A (en) 1989-01-12 1993-06-08 Washington University Infectious Sindbis virus vectors
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
DE69033109T2 (de) 1989-07-06 1999-11-18 The Regents Of The University Of California, Oakland Rezeptoren für fibroblasten-wachstumsfaktoren
JPH04167172A (ja) 1990-10-31 1992-06-15 Nec Corp ベクトルプロセッサ
US5756671A (en) 1994-06-02 1998-05-26 Mitotix, Inc. CDC37 cell-cycle regulatory protein, and uses related thereto
US6080560A (en) * 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
US5541087A (en) * 1994-09-14 1996-07-30 Fuji Immunopharmaceuticals Corporation Expression and export technology of proteins as immunofusins
US6165460A (en) 1995-07-10 2000-12-26 Therion Biologics Corporation Generation of immune responses to prostate-specific antigen (PSA)
US5925351A (en) 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
DE19535939A1 (de) 1995-09-27 1997-04-03 Agfa Gevaert Ag Fotografisches Material
IL136667A0 (en) 1997-12-08 2001-06-14 Beth Israel Hospital Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
ES2284247T3 (es) 1998-04-03 2007-11-01 University Of Iowa Research Foundation Metodos y productos para estimular el sistema inmunitario usando oligonucleotidos y citoquinas inmunoterapeuticos.
WO1999062944A2 (en) * 1998-06-03 1999-12-09 The Children's Medical Center Corporation Protein oligomer compositions comprising endostatin protein and methods of using the same
AU4859399A (en) 1998-07-02 2000-01-24 President And Fellows Of Harvard College Compositions and methods for treating papillomavirus-infected cells
JP2003517280A (ja) 1999-02-05 2003-05-27 トーマス・ジェファーソン・ユニバーシティ トランス相補性システムを用いての植物における生物医学用ペプチド及びタンパク質の生成
US6656728B1 (en) 1999-02-08 2003-12-02 Chiron Corporation Fibroblast growth factor receptor-immunoglobulin fusion
US7692063B2 (en) * 2002-11-12 2010-04-06 Ibio, Inc. Production of foreign nucleic acids and polypeptides in sprout systems
EP1594956A4 (en) 2003-02-03 2007-08-01 Fraunhofer Usa Inc SYSTEM FOR EXPRESSION OF GENES IN PLANTS
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon
JP2010531666A (ja) * 2007-06-26 2010-09-30 ユニバーシティ オブ マイアミ 抗体−エンドスタチン融合タンパク質及びそのバリアント
US8507441B2 (en) 2009-10-22 2013-08-13 University of Pittsburgh—Of the Commonwealth Systems of Higher Education Use of endostatin peptides for the treatment of fibrosis
CA2842330A1 (en) * 2011-07-19 2013-01-24 Thrasos Innovation, Inc. Anti-fibrotic peptides and their use in methods for treating diseases and disorders characterized by fibrosis
JP6952685B2 (ja) 2015-06-05 2021-10-20 アイバイオ・インコーポレイテッドIbio, Inc. 線維症の治療において使用するためのエンドスタチン断片およびバリアント

Similar Documents

Publication Publication Date Title
JP2018524019A5 (OSRAM)
AU2014288147B2 (en) Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
JP2015505299A5 (OSRAM)
RS58436B1 (sr) Stabilizovani rastvorljivi pre-fuzioni rsv f polipeptidi
JP2009540801A5 (OSRAM)
JP2018537087A5 (OSRAM)
JP2012501959A5 (OSRAM)
JP2017506886A5 (OSRAM)
JP2014525239A5 (OSRAM)
RU2014126587A (ru) Химерная частица hpv
JP2024180560A5 (OSRAM)
JP2015509506A5 (OSRAM)
EP3464331A1 (en) Stabilized pre-fusion rsv f proteins
TW202130363A (zh) 變異型rsv f蛋白質及其利用
JP2014519817A5 (OSRAM)
WO2022127825A1 (zh) 针对新型冠状病毒感染的疫苗组合物
CN103184230B (zh) 一种融合蛋白基因TAT-sVP7及其应用
CN108727503A (zh) VZV重组gE-鞭毛素融合蛋白及其制备方法和应用
US9925259B2 (en) Immunogenic polypeptide surface layer-expressing bifidobacterium
JP2018533908A5 (OSRAM)
JP2016521566A5 (OSRAM)
JP2015536347A5 (OSRAM)
CN113430178B (zh) 一种表达ii型单纯疱疹病毒蛋白的重组流感病毒株及其制备方法与应用
CN103102418B (zh) 粒细胞集落刺激因子(G-CSF)及其突变体(mG-CSF)与人血清白蛋白第三结构域(3DHSA)的融合蛋白及应用
Elkins et al. Plant production and functional characterization of catfish interleukin-22 as a natural immune stimulant for aquaculture fish