JP2018523105A5 - - Google Patents
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- JP2018523105A5 JP2018523105A5 JP2017563088A JP2017563088A JP2018523105A5 JP 2018523105 A5 JP2018523105 A5 JP 2018523105A5 JP 2017563088 A JP2017563088 A JP 2017563088A JP 2017563088 A JP2017563088 A JP 2017563088A JP 2018523105 A5 JP2018523105 A5 JP 2018523105A5
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- Japan
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- therapeutic compound
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562170099P | 2015-06-02 | 2015-06-02 | |
| US62/170,099 | 2015-06-02 | ||
| US201562237905P | 2015-10-06 | 2015-10-06 | |
| US62/237,905 | 2015-10-06 | ||
| PCT/US2016/035198 WO2016196580A1 (en) | 2015-06-02 | 2016-06-01 | Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523105A JP2018523105A (ja) | 2018-08-16 |
| JP2018523105A5 true JP2018523105A5 (enExample) | 2019-05-16 |
| JP6585737B2 JP6585737B2 (ja) | 2019-10-02 |
Family
ID=57441615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563088A Active JP6585737B2 (ja) | 2015-06-02 | 2016-06-01 | セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10338077B2 (enExample) |
| EP (1) | EP3304076A4 (enExample) |
| JP (1) | JP6585737B2 (enExample) |
| WO (1) | WO2016196580A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016012795A2 (pt) | 2013-12-06 | 2017-08-08 | Celgene Corp | Métodos para a determinação da eficácia do fármaco para o tratamento de linfoma difuso de grandes células b, mieloma múltiplo e cânceres mieloides |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| WO2017120446A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
| EP3422002B1 (de) | 2017-06-26 | 2020-04-08 | Bioscientia Institut für Medizinische Diagnostik GmbH | Screeningverfahren zur diagnose einer hämatologischen neoplasie |
| TWI793151B (zh) | 2017-08-23 | 2023-02-21 | 瑞士商諾華公司 | 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途 |
| AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
| BR122022012697B1 (pt) | 2018-07-10 | 2023-04-04 | Novartis Ag | Usos de derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6- diona, e kit |
| US20210395829A1 (en) * | 2018-10-04 | 2021-12-23 | Alfred Health | Methods for monitoring response to treatment |
| US12227488B2 (en) | 2018-12-03 | 2025-02-18 | Dana-Farber Cancer Institute, Inc. | Small molecule degraders of Helios and methods of use |
| MX2021007392A (es) * | 2018-12-20 | 2021-08-24 | Novartis Ag | Regimen de dosificacion y combinacion farmaceutica que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona. |
| AU2021413227A1 (en) | 2020-12-31 | 2023-07-13 | Elephas Biosciences Corporation | Ex vivo systems and methods for determining the effect of a drug or other agent on a tissue |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012125405A2 (en) | 2011-03-11 | 2012-09-20 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing responsiveness to lenalidomide, thalidomide, and/or other thalidomide analogs |
| MX353482B (es) | 2011-04-29 | 2018-01-16 | Celgene Corp | Metodos para el tratamiento del cancer y enfermedades inflamatorias utilizando cereblon como predictor. |
| CA3136093C (en) | 2012-06-29 | 2025-07-08 | Celgene Corporation | METHODS FOR DETERMINING THE EFFICACY OF A DRUG USING PROTEINS ASSOCIATED WITH CEREBLON |
| CA2884103A1 (en) * | 2012-09-10 | 2014-03-13 | Celgene Corporation | Methods for the treatment of locally advanced breast cancer |
| WO2014179661A1 (en) * | 2013-05-03 | 2014-11-06 | Celgene Corporation | Methods for treating cancer using combination therapy |
| BR112016012795A2 (pt) | 2013-12-06 | 2017-08-08 | Celgene Corp | Métodos para a determinação da eficácia do fármaco para o tratamento de linfoma difuso de grandes células b, mieloma múltiplo e cânceres mieloides |
| WO2015085160A2 (en) | 2013-12-06 | 2015-06-11 | Celgene Corporation | Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunodulatory therapies |
| US20170242014A1 (en) | 2014-10-13 | 2017-08-24 | Celgene Corporaton | Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| US20170038387A1 (en) | 2015-08-04 | 2017-02-09 | Celgene Corporation | Methods for treating chronic lymphocytic leukemia and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| JP2018525991A (ja) | 2015-08-12 | 2018-09-13 | セルジーン コーポレイション | 固形腫瘍の治療方法及び免疫調節療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| WO2017120446A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
-
2016
- 2016-06-01 WO PCT/US2016/035198 patent/WO2016196580A1/en not_active Ceased
- 2016-06-01 US US15/170,789 patent/US10338077B2/en active Active
- 2016-06-01 EP EP16804297.6A patent/EP3304076A4/en active Pending
- 2016-06-01 JP JP2017563088A patent/JP6585737B2/ja active Active
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