JP6585737B2 - セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 - Google Patents

セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 Download PDF

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JP6585737B2
JP6585737B2 JP2017563088A JP2017563088A JP6585737B2 JP 6585737 B2 JP6585737 B2 JP 6585737B2 JP 2017563088 A JP2017563088 A JP 2017563088A JP 2017563088 A JP2017563088 A JP 2017563088A JP 6585737 B2 JP6585737 B2 JP 6585737B2
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JP2018523105A (ja
JP2018523105A5 (enExample
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英克 伊波
英克 伊波
詠美 池辺
詠美 池辺
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Celgene Corp
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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JP2017563088A 2015-06-02 2016-06-01 セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 Active JP6585737B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562170099P 2015-06-02 2015-06-02
US62/170,099 2015-06-02
US201562237905P 2015-10-06 2015-10-06
US62/237,905 2015-10-06
PCT/US2016/035198 WO2016196580A1 (en) 2015-06-02 2016-06-01 Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins

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JP2018523105A JP2018523105A (ja) 2018-08-16
JP2018523105A5 JP2018523105A5 (enExample) 2019-05-16
JP6585737B2 true JP6585737B2 (ja) 2019-10-02

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US (1) US10338077B2 (enExample)
EP (1) EP3304076A4 (enExample)
JP (1) JP6585737B2 (enExample)
WO (1) WO2016196580A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015085172A2 (en) 2013-12-06 2015-06-11 Celgene Corporation Methods for determining drug efficacy for the treatment of diffuse large b-cell lymphoma, multiple myeloma, and myeloid cancers
AU2016326499A1 (en) 2015-09-25 2018-04-12 Celgene Corporation Methods for treating diffuse large B-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
EP3399980B1 (en) 2016-01-08 2025-07-16 Celgene Corporation Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies
EP3422002B1 (de) 2017-06-26 2020-04-08 Bioscientia Institut für Medizinische Diagnostik GmbH Screeningverfahren zur diagnose einer hämatologischen neoplasie
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
BR122022012697B1 (pt) 2018-07-10 2023-04-04 Novartis Ag Usos de derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6- diona, e kit
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
CN112912516A (zh) * 2018-10-04 2021-06-04 阿尔佛雷德医疗集团 监测对治疗的反应的方法
CN113490495B (zh) * 2018-12-03 2024-09-27 达纳-法伯癌症研究公司 Helios的小分子降解剂及其使用方法
AU2019402189B2 (en) * 2018-12-20 2023-04-13 Novartis Ag Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
US11366101B1 (en) 2020-12-31 2022-06-21 Elephas Biosciences Corporation Ex vivo systems and methods for determining the effect of a drug or other agent on a tissue

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US9662319B2 (en) 2011-03-11 2017-05-30 Mayo Foundation For Medical Education And Research Methods and materials for assessing responsiveness to lenalidomide, thalidomide, and/or other thalidomide analogs
WO2012149299A2 (en) 2011-04-29 2012-11-01 Celgene Corporaiton Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
ES2872967T3 (es) 2012-06-29 2021-11-03 Celgene Corp Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS)
CN104797256A (zh) * 2012-09-10 2015-07-22 细胞基因公司 用于治疗局部晚期乳腺癌的方法
WO2014179661A1 (en) * 2013-05-03 2014-11-06 Celgene Corporation Methods for treating cancer using combination therapy
WO2015085172A2 (en) 2013-12-06 2015-06-11 Celgene Corporation Methods for determining drug efficacy for the treatment of diffuse large b-cell lymphoma, multiple myeloma, and myeloid cancers
BR112016012792A2 (pt) 2013-12-06 2017-08-08 Celgene Corp Métodos para o tratamento de cânceres hematológicos e o uso de biomarcadores como um preditor de sensibilidade clínica a terapias imunomoduladoras
JP2017533727A (ja) 2014-10-13 2017-11-16 セルジーン コーポレイション 固形腫瘍の治療方法及び免疫調節療法への臨床的感度の予測因子としてのバイオマーカーの使用
US20170038387A1 (en) 2015-08-04 2017-02-09 Celgene Corporation Methods for treating chronic lymphocytic leukemia and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies
US20180231561A1 (en) 2015-08-12 2018-08-16 Celgene Corporation Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies
AU2016326499A1 (en) 2015-09-25 2018-04-12 Celgene Corporation Methods for treating diffuse large B-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
EP3399980B1 (en) 2016-01-08 2025-07-16 Celgene Corporation Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies

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JP2018523105A (ja) 2018-08-16
US20160356778A1 (en) 2016-12-08
EP3304076A4 (en) 2018-12-19
EP3304076A1 (en) 2018-04-11
US10338077B2 (en) 2019-07-02
WO2016196580A1 (en) 2016-12-08

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