JP2018522578A5 - - Google Patents
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- JP2018522578A5 JP2018522578A5 JP2018511346A JP2018511346A JP2018522578A5 JP 2018522578 A5 JP2018522578 A5 JP 2018522578A5 JP 2018511346 A JP2018511346 A JP 2018511346A JP 2018511346 A JP2018511346 A JP 2018511346A JP 2018522578 A5 JP2018522578 A5 JP 2018522578A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- antigen
- binding fragment
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021136205A JP2022008301A (ja) | 2015-05-12 | 2021-08-24 | ヒト化型親和性成熟抗ＦｃＲｎ抗体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562160423P | 2015-05-12 | 2015-05-12 | |
| US62/160,423 | 2015-05-12 | ||
| US201562217490P | 2015-09-11 | 2015-09-11 | |
| US62/217,490 | 2015-09-11 | ||
| PCT/US2016/032168 WO2016183352A1 (en) | 2015-05-12 | 2016-05-12 | Humanized affinity matured anti-fcrn antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021136205A Division JP2022008301A (ja) | 2015-05-12 | 2021-08-24 | ヒト化型親和性成熟抗ＦｃＲｎ抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522578A JP2018522578A (ja) | 2018-08-16 |
| JP2018522578A5 true JP2018522578A5 (https=) | 2019-06-13 |
| JP6936217B2 JP6936217B2 (ja) | 2021-09-15 |
Family
ID=57249466
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018511346A Expired - Fee Related JP6936217B2 (ja) | 2015-05-12 | 2016-05-12 | ヒト化型親和性成熟抗ＦｃＲｎ抗体 |
| JP2021136205A Pending JP2022008301A (ja) | 2015-05-12 | 2021-08-24 | ヒト化型親和性成熟抗ＦｃＲｎ抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021136205A Pending JP2022008301A (ja) | 2015-05-12 | 2021-08-24 | ヒト化型親和性成熟抗ＦｃＲｎ抗体 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10626175B2 (https=) |
| EP (1) | EP3294335B1 (https=) |
| JP (2) | JP6936217B2 (https=) |
| KR (1) | KR20180023900A (https=) |
| CN (2) | CN114716550A (https=) |
| AU (2) | AU2016262100B2 (https=) |
| CA (1) | CA3022547A1 (https=) |
| ES (1) | ES2956662T3 (https=) |
| HK (1) | HK1251483A1 (https=) |
| IL (1) | IL255601A (https=) |
| WO (1) | WO2016183352A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2892924B1 (en) * | 2012-06-14 | 2020-11-25 | Therapix Biosciences Ltd. | Humanized antibodies to cluster of differentiation 3 (cd3) |
| CN112142843B (zh) | 2013-12-24 | 2024-10-18 | 阿尔金克斯有限公司 | FcRn拮抗剂及使用方法 |
| KR20250052465A (ko) | 2015-01-30 | 2025-04-18 | 모멘타 파머슈티컬스 인코포레이티드 | ＦｃＲｎ 항체 및 이의 사용 방법 |
| CN106957365B (zh) | 2016-01-11 | 2021-03-16 | 上海交通大学 | 一种单克隆抗体FnAb8及其应用 |
| ES2864211T3 (es) * | 2016-04-25 | 2021-10-13 | Syntimmune Inc | Anticuerpos anti-FcRn humanizados con maduración de la afinidad |
| CA3032415A1 (en) | 2016-07-29 | 2018-02-01 | Momenta Pharmaceuticals, Inc. | Fcrn antibodies and methods of use thereof |
| US12240875B2 (en) | 2017-12-08 | 2025-03-04 | argenx BV | Use of FCRN antagonists for treatment of generalized myasthenia gravis |
| KR102904658B1 (ko) * | 2017-12-13 | 2025-12-29 | 모멘타 파머슈티컬스 인코포레이티드 | FcRn 항체 및 이의 사용 방법 |
| WO2019160979A1 (en) * | 2018-02-13 | 2019-08-22 | The Brigham And Women's Hospital, Inc. | Therapeutic fcrn-based bispecific monoclonal antibodies |
| CA3101462A1 (en) | 2018-06-08 | 2019-12-12 | Argenx Bvba | Compositions and methods for treating immune thrombocytopenia |
| KR102921210B1 (ko) | 2018-07-20 | 2026-01-30 | 모멘타 파머슈티컬스 인코포레이티드 | Fcrn 항체 조성물 |
| CN113194966A (zh) * | 2018-10-03 | 2021-07-30 | 柰裴斯生命科学公司 | 抗cd79抗体及其应用 |
| US20220002402A1 (en) * | 2018-11-06 | 2022-01-06 | Immunovant Sciences Gmbh | Methods of treating graves' ophthalmopathy using anti-fcrn antibodies |
| WO2020236695A1 (en) * | 2019-05-17 | 2020-11-26 | Alexion Pharmaceuticals, Inc. | Use of anti-fcrn antibodies in the treatment of pemphighus and pemphigoid diseases |
| CN114126647A (zh) | 2019-06-07 | 2022-03-01 | 阿尔金克斯有限公司 | 适用于皮下施用的FcRn抑制剂的药物制剂 |
| EP3763737A1 (en) * | 2019-07-12 | 2021-01-13 | Eberhard Karls Universität Tübingen | Binding compounds of penicillin binding protein 2 a |
| US20230049011A1 (en) * | 2019-11-19 | 2023-02-16 | Immunovant Sciences Gmbh | Methods of treating warm autoimmune hemolytic anemia using anti-fcrn antibodies |
| BR112022013554A2 (pt) | 2020-01-08 | 2022-09-06 | argenx BV | Métodos para tratar distúrbios do pênfigo |
| CN113484526B (zh) * | 2021-08-11 | 2024-08-23 | 上海迈晋生物医药科技有限公司 | 一种抗FcRn抗体或其抗原结合片段生物学活性的检测方法 |
| US20250136699A1 (en) * | 2021-08-13 | 2025-05-01 | Jiangsu Biojetay Biotechnology Co., Ltd. | Antibodies specifically recognizing fcrn and uses thereof |
| CN116234827A (zh) * | 2021-09-03 | 2023-06-06 | 舒泰神（北京）生物制药股份有限公司 | 特异性识别FcRn的抗体及其应用 |
| CN114129730A (zh) * | 2021-09-16 | 2022-03-04 | 宁夏大学 | FcRn抑制剂在制备降低炎症反应和/或防治结核病的试剂或药物中的应用 |
| AU2023281650A1 (en) | 2022-05-30 | 2024-10-17 | Hanall Biopharma Co., Ltd. | Anti-fcrn antibody or antigen binding fragment thereof with improved stability |
| CA3258000A1 (en) | 2022-06-15 | 2023-12-21 | argenx BV | FCRN/ANTIGEN BINDING MOLECULES AND METHODS OF USE |
| CN115645537A (zh) * | 2022-10-25 | 2023-01-31 | 成都臻拓医药科技有限公司 | FcRn抑制剂在制备抑制自身免疫性疾病复发的药物中的用途 |
| WO2025099576A1 (en) | 2023-11-06 | 2025-05-15 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating rheumatoid arthritis |
| WO2025163617A1 (en) | 2024-02-04 | 2025-08-07 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating sjögren's disease |
| WO2025232879A1 (en) | 2024-05-10 | 2025-11-13 | Cytocares (Shanghai) Inc. | Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| US6992234B2 (en) * | 2000-11-06 | 2006-01-31 | The Jackson Laboratory | FcRn-based therapeutics for the treatment of auto-immune disorders |
| JP4685764B2 (ja) * | 2003-04-10 | 2011-05-18 | アボット バイオセラピューティクス コーポレイション | 変異誘発による抗体のＦｃＲｎ結合親和力又は血清半減期の改変 |
| US20050106667A1 (en) | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| JP2007501847A (ja) * | 2003-08-08 | 2007-02-01 | ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク | 自己／同種免疫状態の治療用抗ＦｃＲｎ抗体 |
| CA2606378A1 (en) * | 2005-04-29 | 2006-11-09 | The Jackson Laboratory | Fcrn antibodies and uses thereof |
| EP1790716A1 (en) * | 2005-11-23 | 2007-05-30 | UMC Utrecht Holding B.V. | Uses of the FcRn receptor |
| JP2009524664A (ja) | 2006-01-25 | 2009-07-02 | ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク | 自己／アロ免疫疾患の治療のための抗−ｆｃｒｎ抗体 |
| BRPI0910622A2 (pt) * | 2008-04-25 | 2020-03-10 | Dyax Corp. | ANTICORPOS CONTRA FcRn E USOS DOS MESMOS |
| WO2011042548A1 (en) * | 2009-10-09 | 2011-04-14 | Sanofi-Aventis | Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same |
| ES2751549T3 (es) * | 2009-11-30 | 2020-04-01 | Janssen Biotech Inc | Mutantes de anticuerpos Fc con funciones efectoras ablacionadas |
| EP2785743B1 (en) * | 2011-12-01 | 2019-08-14 | The Brigham and Women's Hospital, Inc. | Anti-ceacam1 recombinant antibodies for cancer therapy |
| GB201208370D0 (en) * | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Antibodies |
| CA2983796A1 (en) | 2014-04-25 | 2015-10-29 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating subjects with immune-mediated diseases |
-
2016
- 2016-05-12 ES ES16793546T patent/ES2956662T3/es active Active
- 2016-05-12 CA CA3022547A patent/CA3022547A1/en not_active Abandoned
- 2016-05-12 HK HK18111124.6A patent/HK1251483A1/zh unknown
- 2016-05-12 WO PCT/US2016/032168 patent/WO2016183352A1/en not_active Ceased
- 2016-05-12 CN CN202210374599.XA patent/CN114716550A/zh active Pending
- 2016-05-12 EP EP16793546.9A patent/EP3294335B1/en active Active
- 2016-05-12 AU AU2016262100A patent/AU2016262100B2/en not_active Ceased
- 2016-05-12 JP JP2018511346A patent/JP6936217B2/ja not_active Expired - Fee Related
- 2016-05-12 KR KR1020177035833A patent/KR20180023900A/ko not_active Ceased
- 2016-05-12 CN CN201680040516.6A patent/CN108025066B/zh active Active
-
2017
- 2017-11-12 IL IL255601A patent/IL255601A/en unknown
- 2017-11-13 US US15/811,218 patent/US10626175B2/en active Active
-
2020
- 2020-02-25 US US16/800,458 patent/US20200207854A1/en not_active Abandoned
- 2020-02-25 US US16/800,480 patent/US20200181262A1/en not_active Abandoned
-
2021
- 2021-08-24 JP JP2021136205A patent/JP2022008301A/ja active Pending
-
2022
- 2022-01-05 AU AU2022200024A patent/AU2022200024A1/en not_active Abandoned
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