JP2018520127A - Ｍｃｍ５に結合するモノクローナル抗体 - Google Patents

Ｍｃｍ５に結合するモノクローナル抗体 Download PDF

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Publication number
JP2018520127A
JP2018520127A JP2017564337A JP2017564337A JP2018520127A JP 2018520127 A JP2018520127 A JP 2018520127A JP 2017564337 A JP2017564337 A JP 2017564337A JP 2017564337 A JP2017564337 A JP 2017564337A JP 2018520127 A JP2018520127 A JP 2018520127A
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JP
Japan
Prior art keywords
antibody
seq
sequence
mcm5
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017564337A
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English (en)
Japanese (ja)
Other versions
JP2018520127A5 (enExample
Inventor
アルフレッド ラスキー，ロナルド
アルフレッド ラスキー，ロナルド
ストーバー，カイ
Original Assignee
アーケア ダイアグノスティクス リミテッド
アーケア ダイアグノスティクス リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アーケア ダイアグノスティクス リミテッド, アーケア ダイアグノスティクス リミテッド filed Critical アーケア ダイアグノスティクス リミテッド
Publication of JP2018520127A publication Critical patent/JP2018520127A/ja
Publication of JP2018520127A5 publication Critical patent/JP2018520127A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017564337A 2015-06-08 2016-06-01 Ｍｃｍ５に結合するモノクローナル抗体 Pending JP2018520127A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1509907.0 2015-06-08
GBGB1509907.0A GB201509907D0 (en) 2015-06-08 2015-06-08 Antibodies
PCT/GB2016/051609 WO2016198834A1 (en) 2015-06-08 2016-06-01 Monoclonal antibodies binding mcm5

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020084210A Division JP2020156486A (ja) 2015-06-08 2020-05-13 Ｍｃｍ５に結合するモノクローナル抗体

Publications (2)

Publication Number Publication Date
JP2018520127A true JP2018520127A (ja) 2018-07-26
JP2018520127A5 JP2018520127A5 (enExample) 2019-07-04

Family

ID=53785114

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017564337A Pending JP2018520127A (ja) 2015-06-08 2016-06-01 Ｍｃｍ５に結合するモノクローナル抗体
JP2020084210A Pending JP2020156486A (ja) 2015-06-08 2020-05-13 Ｍｃｍ５に結合するモノクローナル抗体
JP2022110175A Pending JP2022165963A (ja) 2015-06-08 2022-07-08 Ｍｃｍ５に結合するモノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2020084210A Pending JP2020156486A (ja) 2015-06-08 2020-05-13 Ｍｃｍ５に結合するモノクローナル抗体
JP2022110175A Pending JP2022165963A (ja) 2015-06-08 2022-07-08 Ｍｃｍ５に結合するモノクローナル抗体

Country Status (8)

Country Link
US (2) US20180186892A1 (enExample)
EP (1) EP3221352B1 (enExample)
JP (3) JP2018520127A (enExample)
CN (1) CN107810200B (enExample)
ES (1) ES2678049T3 (enExample)
GB (1) GB201509907D0 (enExample)
TR (1) TR201808196T4 (enExample)
WO (1) WO2016198834A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020156486A (ja) * 2015-06-08 2020-10-01 アーケア ダイアグノスティクス リミテッド Ｍｃｍ５に結合するモノクローナル抗体
JP2022513525A (ja) * 2018-12-20 2022-02-08 アーケア ダイアグノスティクス リミテッド 婦人科がんのマーカーとしてのｍｃｍ５の使用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201820868D0 (en) * 2018-12-20 2019-02-06 Arquer Diagnostics Ltd Detection method
GB201912605D0 (en) * 2019-09-02 2019-10-16 Arquer Diagnostics Ltd Cancer assay
CN118359714B (zh) * 2024-06-14 2024-10-22 浙江莱阅病理诊断科技有限公司 一种抗mcm2鼠单克隆抗体及其制备方法和免疫组化试剂的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1025444B1 (en) * 1997-10-21 2005-03-02 Cancer Research Technology Limited Determination of cellular growth abnormality
WO2005026211A2 (en) * 2003-09-05 2005-03-24 Eli Lilly And Company Anti-ghrelin antibodies
GB0708002D0 (en) * 2007-04-25 2007-06-06 Univ Sheffield Antibodies
GB201509907D0 (en) * 2015-06-08 2015-07-22 Urosens Ltd Antibodies

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BR J CANCER (2008) VOL.98, NO.9, P.1548-1554, JPN6020025312, ISSN: 0004306607 *
BRITISH JOURNAL OF CANCER (2004) VOL.91, P.714-719, JPN6020025310, ISSN: 0004306605 *
BRITISH JOURNAL OF CANCER, vol. 103, JPN6019025061, 2010, pages 701 - 707, ISSN: 0004068149 *
JOURNAL OF THE NATIONAL CANCER INSTITUTE, vol. 94(14), JPN6019025058, 2002, pages 1071 - 1079, ISSN: 0004068148 *
PLOS ONE (2012) VOLUME 7, ISSUE 7, E40305(P.1-9), JPN6020025311, ISSN: 0004306606 *
製品カタログ「APPLICATIONS OF TIME-RESOLEVED FLUOROMETRY WITH THE DELFIA METHOD」, JPN6019025064, 2006, pages 全文, ISSN: 0004068150 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020156486A (ja) * 2015-06-08 2020-10-01 アーケア ダイアグノスティクス リミテッド Ｍｃｍ５に結合するモノクローナル抗体
JP2022513525A (ja) * 2018-12-20 2022-02-08 アーケア ダイアグノスティクス リミテッド 婦人科がんのマーカーとしてのｍｃｍ５の使用

Also Published As

Publication number Publication date
EP3221352A1 (en) 2017-09-27
CN107810200A (zh) 2018-03-16
TR201808196T4 (tr) 2018-07-23
JP2022165963A (ja) 2022-11-01
GB201509907D0 (en) 2015-07-22
US20210277142A1 (en) 2021-09-09
CN107810200B (zh) 2021-04-06
WO2016198834A1 (en) 2016-12-15
EP3221352B1 (en) 2018-05-09
US20180186892A1 (en) 2018-07-05
JP2020156486A (ja) 2020-10-01
ES2678049T3 (es) 2018-08-08

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