JP2018517495A5 - - Google Patents
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- JP2018517495A5 JP2018517495A5 JP2017563052A JP2017563052A JP2018517495A5 JP 2018517495 A5 JP2018517495 A5 JP 2018517495A5 JP 2017563052 A JP2017563052 A JP 2017563052A JP 2017563052 A JP2017563052 A JP 2017563052A JP 2018517495 A5 JP2018517495 A5 JP 2018517495A5
- Authority
- JP
- Japan
- Prior art keywords
- ultrasound
- transducers
- therapy device
- stimulation therapy
- ultrasound stimulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000002604 ultrasonography Methods 0.000 claims 35
- 230000000638 stimulation Effects 0.000 claims 20
- 238000002560 therapeutic procedure Methods 0.000 claims 13
- 101100478278 Mus musculus Spta1 gene Proteins 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000003481 heat shock protein 90 inhibitor Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562170378P | 2015-06-03 | 2015-06-03 | |
| US62/170,378 | 2015-06-03 | ||
| US201562204312P | 2015-08-12 | 2015-08-12 | |
| US62/204,312 | 2015-08-12 | ||
| PCT/US2016/035440 WO2016196741A2 (en) | 2015-06-03 | 2016-06-02 | Low intensity focused ultrasound for treating cancer and metastasis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020206143A Division JP7105294B2 (ja) | 2015-06-03 | 2020-12-11 | 癌と転移を処置するための低密度焦点式超音波 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018517495A JP2018517495A (ja) | 2018-07-05 |
| JP2018517495A5 true JP2018517495A5 (enExample) | 2019-07-04 |
| JP6819012B2 JP6819012B2 (ja) | 2021-01-27 |
Family
ID=57442265
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563052A Active JP6819012B2 (ja) | 2015-06-03 | 2016-06-02 | 癌と転移を処置するための低密度焦点式超音波 |
| JP2020206143A Active JP7105294B2 (ja) | 2015-06-03 | 2020-12-11 | 癌と転移を処置するための低密度焦点式超音波 |
| JP2022111273A Active JP7635177B2 (ja) | 2015-06-03 | 2022-07-11 | 癌と転移を処置するための低密度焦点式超音波 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020206143A Active JP7105294B2 (ja) | 2015-06-03 | 2020-12-11 | 癌と転移を処置するための低密度焦点式超音波 |
| JP2022111273A Active JP7635177B2 (ja) | 2015-06-03 | 2022-07-11 | 癌と転移を処置するための低密度焦点式超音波 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10974077B2 (enExample) |
| EP (1) | EP3302264B1 (enExample) |
| JP (3) | JP6819012B2 (enExample) |
| CN (2) | CN114886412B (enExample) |
| WO (1) | WO2016196741A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11179581B2 (en) | 2015-03-09 | 2021-11-23 | The Research Foundation For The State University Of New York | Systems and methods for promoting cellular activities for tissue maintenance, repair, and regeneration |
| EP3302264B1 (en) * | 2015-06-03 | 2025-03-19 | Montefiore Medical Center | Low intensity focused ultrasound for treating cancer and metastasis |
| EP3525883A4 (en) | 2016-10-16 | 2020-12-02 | Vibrato Medical, Inc. | EXTRACORPORAL THERAPEUTIC ULTRASOUND TO PROMOTE ANGIOGENESIS |
| CN111836666A (zh) * | 2017-11-09 | 2020-10-27 | 蒙特非奥里医疗中心 | 用于治疗癌症和转移的低能量免疫致敏 |
| CA3122353A1 (en) * | 2017-12-22 | 2019-06-27 | Freedom Waves S.R.L. | System for inducing sonoporation of a drug into cancer cells and method thereof |
| US11260249B2 (en) * | 2018-07-19 | 2022-03-01 | Sonablate Corp. | System, apparatus and method for high intensity focused ultrasound and tissue healing activation |
| JP2020110282A (ja) * | 2019-01-10 | 2020-07-27 | 治 三宅 | 生体用の超音波照射治療装置 |
| WO2020167992A1 (en) | 2019-02-13 | 2020-08-20 | Craniovation, Inc. | Non-invasive sonodynamic therapy |
| EP3923814B1 (fr) * | 2019-02-15 | 2025-11-19 | Boysset, Max | Pièce d'habillement pour contrôle de cellules |
| CN110507917A (zh) * | 2019-07-30 | 2019-11-29 | 哈尔滨医科大学 | 一种超高场磁共振引导的低强度聚焦超声爆破系统 |
| US20220288418A1 (en) * | 2019-08-27 | 2022-09-15 | Montefiore Medical Center | Post-ablative modulation of radiation therapy |
| US20210169979A1 (en) * | 2019-12-05 | 2021-06-10 | The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges | System and method for sonosensitized cancer immunotherapy with nanoparticles |
| AU2021320883A1 (en) * | 2020-08-06 | 2023-03-30 | Montefiore Medical Center | Dendritic cell activating therapy as an adjunct to radiation therapy |
| CA3185803A1 (en) | 2020-08-07 | 2022-02-10 | Vijay Agarwal | Ultrasound arrays for enhanced sonodynamic therapy for treating cancer |
| US12245355B2 (en) | 2021-02-19 | 2025-03-04 | Mevion Medical Systems, Inc. | Gantry for a particle therapy system |
| WO2022197662A2 (en) * | 2021-03-15 | 2022-09-22 | Guided Therapy Systems, Llc | Method for mid-intensity, non-ablative acoustic treatment of injured tissue |
| WO2023060199A1 (en) * | 2021-10-06 | 2023-04-13 | The Trustees Of Columbia University In The City Of New York | Method and integrated system for selective removal of defective cells and edematous fluids from the lung |
| WO2023105290A1 (en) * | 2021-12-10 | 2023-06-15 | Insightec, Ltd. | Short-pulse sonodynamic treatment apparatus |
| US20230293913A1 (en) * | 2022-03-17 | 2023-09-21 | Open Water Internet Inc. | Harmonic excitation therapy and anti-tumor agent |
| JP2025527723A (ja) * | 2022-08-22 | 2025-08-22 | レーザーリープテクノロジーズ エス.エー. | 固形腫瘍を圧力パルスでプライミングし、抗がん治療を強化するための装置および方法 |
| WO2024246914A1 (en) * | 2023-06-01 | 2024-12-05 | B.G. Negev Technologies And Applications Ltd. | Therapeutic ultrasound methods |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0068961A3 (fr) | 1981-06-26 | 1983-02-02 | Thomson-Csf | Dispositif d'échauffement localisé de tissus biologiques |
| US7510536B2 (en) | 1999-09-17 | 2009-03-31 | University Of Washington | Ultrasound guided high intensity focused ultrasound treatment of nerves |
| WO2001032258A2 (en) | 1999-11-01 | 2001-05-10 | University Of Cincinnati | Transcranial ultrasound thrombolysis system and method of treating a stroke |
| US6725095B2 (en) | 2000-04-13 | 2004-04-20 | Celsion Corporation | Thermotherapy method for treatment and prevention of cancer in male and female patients and cosmetic ablation of tissue |
| US6821274B2 (en) * | 2001-03-07 | 2004-11-23 | Gendel Ltd. | Ultrasound therapy for selective cell ablation |
| US20100087728A1 (en) | 2000-11-28 | 2010-04-08 | Physiosonics, Inc. | Acoustic palpation using non-invasive ultrasound techniques to identify and localize tissue eliciting biological responses |
| WO2003099382A1 (en) * | 2002-05-23 | 2003-12-04 | Gendel Limited | Ablation device |
| US20040034304A1 (en) | 2001-12-21 | 2004-02-19 | Chikayoshi Sumi | Displacement measurement method and apparatus, strain measurement method and apparatus elasticity and visco-elasticity constants measurement apparatus, and the elasticity and visco-elasticity constants measurement apparatus-based treatment apparatus |
| US7396336B2 (en) | 2003-10-30 | 2008-07-08 | Sherwood Services Ag | Switched resonant ultrasonic power amplifier system |
| US7896821B1 (en) * | 2003-11-14 | 2011-03-01 | Perfusion Technology, LLC | Low intensity directed ultrasound (LODUS) mediated blood brain barrier disruption |
| EP1699354A4 (en) | 2003-12-30 | 2011-01-05 | Medicis Technologies Corp | SYSTEMS AND METHOD FOR THE DESTRUCTION OF FAT FABRICS |
| JP2007521908A (ja) | 2004-02-12 | 2007-08-09 | ニューロソニック リミティド | 生体における塞栓音波制御 |
| KR100537343B1 (ko) * | 2004-10-01 | 2005-12-19 | 주식회사 듀플로젠 | 관절염 치료용 초음파 장치 |
| US20080260650A1 (en) | 2004-10-28 | 2008-10-23 | The General Hospital Corporation | Methods of Detection and Therapy of Inflamed Tissues Using Immune Modulation |
| CN1814323B (zh) * | 2005-01-31 | 2010-05-12 | 重庆海扶(Hifu)技术有限公司 | 一种聚焦超声波治疗系统 |
| US7194063B2 (en) | 2005-02-10 | 2007-03-20 | Brookhaven Science Associates, Llc | Methods for implementing microbeam radiation therapy |
| WO2006113794A2 (en) | 2005-04-20 | 2006-10-26 | Richard Blankenbecler | Treatment to reduce damage from radiation therapy |
| EP1904179A2 (en) * | 2005-06-07 | 2008-04-02 | Koninklijke Philips Electronics N.V. | Method and apparatus for ultrasound drug delivery and thermal therapy with phase-convertible fluids |
| JP4369907B2 (ja) | 2005-07-01 | 2009-11-25 | 株式会社日立製作所 | 音響化学治療装置 |
| CA2616316A1 (en) | 2005-07-22 | 2007-02-01 | Tomotherapy Incorporated | Method and system for adapting a radiation therapy treatment plan based on a biological model |
| WO2007044469A2 (en) * | 2005-10-05 | 2007-04-19 | Perfusion Technology, Llp | A method and apparatus to direct radiation treatment to a specific region of the brain |
| US20070088345A1 (en) | 2005-10-13 | 2007-04-19 | Ust Inc. | Applications of HIFU and chemotherapy |
| WO2010029556A1 (en) * | 2008-09-12 | 2010-03-18 | Slender Medical, Ltd. | A device for ultrasound treatment and monitoring tissue treatment |
| JP5032094B2 (ja) * | 2006-11-06 | 2012-09-26 | テルモ株式会社 | 超音波診断装置および制御プログラム |
| WO2008115830A2 (en) | 2007-03-16 | 2008-09-25 | Cyberheart, Inc. | Radiation treatment planning and delivery for moving targets in the heart |
| CN101820949B (zh) | 2007-03-30 | 2017-05-24 | 皇家飞利浦电子股份有限公司 | 用于引导放疗和其他过程的mri引导的hifu标记法 |
| EP2227147A1 (en) * | 2007-11-21 | 2010-09-15 | Focus Surgery, Inc. | Method of diagnosis and treatment of tumors using high intensity focused ultrasound |
| US20090137996A1 (en) | 2007-11-28 | 2009-05-28 | Debenedictis Leonard C | Nonablative and ablative tissue treatment method and device |
| US8466605B2 (en) * | 2008-03-13 | 2013-06-18 | Ultrashape Ltd. | Patterned ultrasonic transducers |
| JP5597198B2 (ja) * | 2008-07-14 | 2014-10-01 | アリゾナ・ボード・オブ・リージェンツ・フォー・アンド・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティ | 超音波を使用して細胞活動を調節するための方法およびデバイス |
| US8962290B2 (en) | 2008-08-26 | 2015-02-24 | Intelligentnano Inc. | Enhanced animal cell growth using ultrasound |
| WO2010115209A2 (en) | 2009-04-03 | 2010-10-07 | Palomar Medical Technologies, Inc. | Method and apparatus for treatment of tissue |
| CN101642607B (zh) * | 2009-09-01 | 2012-11-28 | 西安交通大学 | 基于阵列换能器的低强度聚焦超声药物控释与监控装置 |
| CN101690677B (zh) * | 2009-10-13 | 2011-09-21 | 西安交通大学 | 聚焦超声治疗组合阵元相控阵及多焦点剪切波成像系统 |
| US20130144192A1 (en) * | 2011-07-17 | 2013-06-06 | Neurotrek, Inc. | Ultrasound neuromodulation treatment of anxiety (including panic attacks) and obsessive-compulsive disorder |
| GB2479598B (en) | 2010-04-16 | 2012-11-21 | Cancercure Technology As | Methods and systems for inducing hyperthermia |
| EP2575966B1 (en) * | 2010-05-27 | 2015-12-16 | Koninklijke Philips N.V. | Ultrasound transducer for selectively generating ultrasound waves and heat |
| US8777854B2 (en) * | 2011-09-06 | 2014-07-15 | General Electric Company | Method and system for ultrasound based automated detection, quantification and tracking of pathologies |
| US20140058293A1 (en) | 2012-05-23 | 2014-02-27 | Sunnybrook Research Institute | Multi-Frequency Ultrasound Device and Method of Operation |
| SG11201408652SA (en) | 2012-06-26 | 2015-01-29 | Biodesix Inc | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| EP2869815A4 (en) * | 2012-07-08 | 2016-03-16 | Sunnybrook Health Sciences Ct | A SYSTEM AND METHOD FOR THE USE OF ULTRASOUND STIMULATED MICROBUBBLE EXPOSURES FOR THE INDUCTION OF CERAMIDA CUMULATION IN ENDOTHELIC AND TUMOR CELLS |
| EP2881043A4 (en) * | 2012-07-30 | 2016-06-22 | Nohsn Co Ltd | ULTRASONIC PROBE HAVING GRADIENT INFORMATION AND DEVICE FOR ULTRASONIC DIAGNOSIS AND TREATMENT USING THE SAME |
| CN102831716A (zh) * | 2012-08-27 | 2012-12-19 | 曲宝源 | 预付费球形膨胀腔低压损立柱式超声波热量表 |
| US9061133B2 (en) * | 2012-12-27 | 2015-06-23 | Brainsonix Corporation | Focused ultrasonic transducer navigation system |
| CA2898732A1 (en) * | 2013-01-18 | 2014-07-24 | Mao CHENGJIAN | Estrogen receptor inhibitors |
| CN203112640U (zh) * | 2013-02-05 | 2013-08-07 | 韩先锋 | 旋流分区式船舶压载水处理装置 |
| US10960233B2 (en) | 2013-03-06 | 2021-03-30 | B.G. Negev Technologies And Applications Ltd. | Low intensity ultrasound therapy |
| US20140276069A1 (en) | 2013-03-15 | 2014-09-18 | EagIEyeMed | Ultrasound probe |
| CN103230648B (zh) * | 2013-04-24 | 2016-09-14 | 重庆医科大学 | 低强度聚焦超声分子显像与治疗系统 |
| EP3066488B1 (en) * | 2013-11-08 | 2018-09-19 | Koninklijke Philips N.V. | Medical apparatus for radiotherapy and ultrasound heating |
| CA2929660A1 (en) | 2013-11-19 | 2015-05-28 | Ethicon, Inc. | Thoracoscopic methods for treatment of bronchial disease |
| TW201521671A (zh) * | 2013-12-11 | 2015-06-16 | Univ Nat Taiwan | 超音波醫療裝置 |
| EP3099325A4 (en) | 2014-01-31 | 2017-10-04 | The General Hospital Corporation Dba Massachusetts General Hospital | Methods of treating and imaging tumor micrometastases using photoactivatable immunoconjugates |
| CN106470735B (zh) | 2014-04-18 | 2019-09-20 | 奥赛拉公司 | 带式换能器超声治疗 |
| NZ734614A (en) | 2015-01-15 | 2022-11-25 | Rodney herring | Diffuse acoustic confocal imager |
| CN104874114A (zh) | 2015-06-01 | 2015-09-02 | 天津大学 | 一种利用低强度超声促进放射治疗效应的系统 |
| EP3302264B1 (en) * | 2015-06-03 | 2025-03-19 | Montefiore Medical Center | Low intensity focused ultrasound for treating cancer and metastasis |
| WO2017079431A1 (en) | 2015-11-05 | 2017-05-11 | The General Hospital Corporation | Methods for treating cancer by enhancing intratumoral immune response |
| KR101875111B1 (ko) | 2016-04-29 | 2018-07-09 | 한국수력원자력 주식회사 | 저선량 방사선을 이용한 암화유전자 Ras-유도 악성 암화 억제 |
| US20180154183A1 (en) | 2016-06-22 | 2018-06-07 | Velayudhan Sahadevan | Normal Tissue Toxicity Reducing Microbeam-Broadbeam Radiotherapy, Skin's Radio-Response Immunotherapy and Mutated Molecular Apheresis Combined Cancer Treatments |
| WO2018126277A1 (en) | 2016-12-31 | 2018-07-05 | Radiation Barrier Llc | Reducing damage from radiation therapy and increasing cancer kill rates by interweaving of low and high dose sessions |
| JP2020503322A (ja) | 2016-12-31 | 2020-01-30 | ラディエーション バリア エルエルシー | 低線量放射線を織り込んで用いることによる化学療法による損傷の減少および癌の死滅率の上昇 |
| CN111836666A (zh) | 2017-11-09 | 2020-10-27 | 蒙特非奥里医疗中心 | 用于治疗癌症和转移的低能量免疫致敏 |
| US12179037B2 (en) | 2018-12-11 | 2024-12-31 | Board Of Regents, The University Of Texas System | Radiotherapies and uses thereof |
| US20220288418A1 (en) | 2019-08-27 | 2022-09-15 | Montefiore Medical Center | Post-ablative modulation of radiation therapy |
-
2016
- 2016-06-02 EP EP16804398.2A patent/EP3302264B1/en active Active
- 2016-06-02 WO PCT/US2016/035440 patent/WO2016196741A2/en not_active Ceased
- 2016-06-02 CN CN202210152097.2A patent/CN114886412B/zh active Active
- 2016-06-02 CN CN201680045882.0A patent/CN108601554B/zh active Active
- 2016-06-02 US US15/578,892 patent/US10974077B2/en active Active
- 2016-06-02 JP JP2017563052A patent/JP6819012B2/ja active Active
-
2020
- 2020-12-11 JP JP2020206143A patent/JP7105294B2/ja active Active
-
2021
- 2021-03-03 US US17/191,497 patent/US12011619B2/en active Active
-
2022
- 2022-07-11 JP JP2022111273A patent/JP7635177B2/ja active Active
-
2024
- 2024-05-08 US US18/658,055 patent/US20240366964A1/en active Pending
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