JP2018510650A5 - - Google Patents
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- JP2018510650A5 JP2018510650A5 JP2017560883A JP2017560883A JP2018510650A5 JP 2018510650 A5 JP2018510650 A5 JP 2018510650A5 JP 2017560883 A JP2017560883 A JP 2017560883A JP 2017560883 A JP2017560883 A JP 2017560883A JP 2018510650 A5 JP2018510650 A5 JP 2018510650A5
- Authority
- JP
- Japan
- Prior art keywords
- cmv
- cells
- cmv vector
- vector
- tcr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020213267A JP2021121185A (ja) | 2015-02-10 | 2020-12-23 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| JP2022126096A JP2022166122A (ja) | 2015-02-10 | 2022-08-08 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562114203P | 2015-02-10 | 2015-02-10 | |
| US62/114,203 | 2015-02-10 | ||
| US201562196520P | 2015-07-24 | 2015-07-24 | |
| US62/196,520 | 2015-07-24 | ||
| US201562220703P | 2015-09-18 | 2015-09-18 | |
| US62/220,703 | 2015-09-18 | ||
| PCT/US2016/017373 WO2016130693A1 (en) | 2015-02-10 | 2016-02-10 | Methods and compositions useful in generating non canonical cd8+ t cell responses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213267A Division JP2021121185A (ja) | 2015-02-10 | 2020-12-23 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018510650A JP2018510650A (ja) | 2018-04-19 |
| JP2018510650A5 true JP2018510650A5 (https=) | 2019-03-22 |
| JP6816031B2 JP6816031B2 (ja) | 2021-01-20 |
Family
ID=56615684
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560883A Expired - Fee Related JP6816031B2 (ja) | 2015-02-10 | 2016-02-10 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| JP2020213267A Pending JP2021121185A (ja) | 2015-02-10 | 2020-12-23 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| JP2022126096A Pending JP2022166122A (ja) | 2015-02-10 | 2022-08-08 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213267A Pending JP2021121185A (ja) | 2015-02-10 | 2020-12-23 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| JP2022126096A Pending JP2022166122A (ja) | 2015-02-10 | 2022-08-08 | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20180298404A1 (https=) |
| EP (2) | EP3256595A4 (https=) |
| JP (3) | JP6816031B2 (https=) |
| KR (1) | KR20170136512A (https=) |
| CN (2) | CN108064304A (https=) |
| AU (1) | AU2016219317A1 (https=) |
| BR (1) | BR112017017092A2 (https=) |
| CA (1) | CA2976245A1 (https=) |
| EA (1) | EA201791806A1 (https=) |
| HK (2) | HK1247638A1 (https=) |
| IL (1) | IL253935B (https=) |
| MA (1) | MA41756A (https=) |
| MX (1) | MX2017010027A (https=) |
| SG (1) | SG11201706454VA (https=) |
| WO (1) | WO2016130693A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201802741T4 (tr) | 2010-05-14 | 2018-03-21 | Univ Oregon Health & Science | Rekombinant hcmv ve rhcmv vektörleri ve bunların kullanımları. |
| HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
| DK2964769T3 (en) * | 2013-03-05 | 2018-12-10 | Univ Oregon Health & Science | Cytomegalovirus vectors enabling control of T cell targeting |
| WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| CN113528466B (zh) | 2014-07-16 | 2024-12-24 | 俄勒冈健康与科学大学 | 包含外源抗原的人巨细胞病毒 |
| JP6816031B2 (ja) | 2015-02-10 | 2021-01-20 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| AU2016342045A1 (en) | 2015-10-22 | 2018-06-07 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| CN108474003A (zh) | 2015-11-20 | 2018-08-31 | 俄勒冈健康与科学大学 | 包含微小rna识别元件的cmv载体 |
| US20200182884A1 (en) | 2016-06-27 | 2020-06-11 | Juno Therapeutics, Inc. | Method of identifying peptide epitopes, molecules that bind such epitopes and related uses |
| US10532099B2 (en) | 2016-10-18 | 2020-01-14 | Oregon Health & Science University | Cytomegalovirus vectors eliciting T cells restricted by major histocompatibility complex E molecules |
| EP3528821A4 (en) | 2016-10-21 | 2020-07-01 | ModernaTX, Inc. | HUMAN CYTOMEGALOVIRUS VACCINE |
| EP3539552A1 (en) * | 2018-03-16 | 2019-09-18 | Deutsches Rheuma-Forschungszentrum Berlin | Activation and expansion of nkg2c+ nk cells |
| US20210301255A1 (en) * | 2018-09-10 | 2021-09-30 | Atara Biotherapeutics, Inc. | Methods for expanding antigen-specific car-t cells, compositions and uses related thereto |
| WO2020188111A1 (en) * | 2019-03-21 | 2020-09-24 | 21C Bio | Vaccine to pathogenic immune activation cells during infections |
| US10632186B1 (en) | 2019-03-21 | 2020-04-28 | 21C Bio | Vaccine to pathogenic immune activation cells during infections |
| US11077185B2 (en) | 2019-03-21 | 2021-08-03 | 21C Bio | Vaccine to pathogenic immune activation cells during infections |
| CN110055228B (zh) * | 2019-04-17 | 2023-04-28 | 华中科技大学同济医学院附属协和医院 | 用于乙肝病毒感染的重组巨细胞病毒与应用 |
| JP2022536122A (ja) * | 2019-06-07 | 2022-08-12 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 腫瘍関連抗原特異的t細胞応答 |
| CN114402080B (zh) | 2019-08-20 | 2024-09-13 | 俄勒冈健康与科学大学 | 人巨细胞病毒的ul18对t细胞应答的调节 |
| MX2022002270A (es) | 2019-08-29 | 2022-03-22 | Vir Biotechnology Inc | Vacunas contra el virus de la hepatitis b. |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| JP2024534189A (ja) | 2021-08-31 | 2024-09-18 | ヴィア・バイオテクノロジー・インコーポレイテッド | 組換えhcmvベクター及びその使用 |
| CA3226978A1 (en) | 2021-08-31 | 2023-03-09 | Vir Biotechnology, Inc. | Tuberculosis vaccines |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US5273876A (en) | 1987-06-26 | 1993-12-28 | Syntro Corporation | Recombinant human cytomegalovirus containing foreign gene |
| DE3853139T2 (de) | 1987-06-26 | 1995-06-14 | Syntro Corp | Rekombinanter, fremde gene enthaltender menschlicher cytomegalovirus und seine verwendung. |
| EP0521427A1 (en) | 1991-07-05 | 1993-01-07 | American Cyanamid Company | Method for identifying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegalovirus |
| WO1995003399A2 (en) | 1993-07-19 | 1995-02-02 | Cantab Pharmaceuticals Research Limited | Production method for preparation of disabled viruses |
| AU2234995A (en) | 1994-04-29 | 1995-11-29 | Pharmacia & Upjohn Company | Feline immunodeficiency virus vaccine |
| US5846806A (en) | 1994-07-29 | 1998-12-08 | American Cyanamid Company | Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression |
| EP0811057B1 (en) | 1995-02-21 | 2006-04-26 | Cantab Pharmaceuticals Research Limited | Viral preparations, vectors, immunogens, and vaccines |
| AU712415B2 (en) | 1995-04-04 | 1999-11-04 | Cell Genesys, Inc. | Transplantation of genetically modified cells having low levels of class I MHC proteins on the cell surface |
| WO1998004285A1 (en) | 1996-07-31 | 1998-02-05 | Ortho Pharmaceutical Corporation | Identification of human cytomegalovirus genes involved in down-regulation of mhc class i heavy chain expression |
| US20030138454A1 (en) | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
| DE19733364A1 (de) | 1997-08-01 | 1999-02-04 | Koszinowski Ulrich H Prof | Verfahren zur Klonierung eines großen Virusgenoms |
| WO1999007869A1 (en) | 1997-08-05 | 1999-02-18 | University Of Florida | Live recombinant vaccine comprising inefficiently or non-replicating virus |
| US7204990B1 (en) | 2000-11-28 | 2007-04-17 | Medimmune Vaccines, Inc. | Attenuation of cytomegalovirus virulence |
| CA2437201C (en) * | 2001-02-02 | 2008-11-18 | Chemocentryx, Inc. | Methods and compositions useful for stimulating an immune response |
| US20040087001A1 (en) | 2001-02-21 | 2004-05-06 | Gabriele Hahn | Recombinant vector containing infectious human cytomegalovirus genome with preserved wild-type characteristics of clinical isolates |
| GB0122232D0 (en) | 2001-09-14 | 2001-11-07 | Medical Res Council | Gene expression |
| MXPA04002631A (es) | 2001-09-20 | 2004-07-08 | Glaxo Group Ltd | Vacunas de adn optimizadas por codon gag-vih. |
| US20030118568A1 (en) | 2001-12-18 | 2003-06-26 | Board Of Trustees Of The University Of Arkansas | Viral stealth technology to prevent T cell-mediated rejection of xenografts |
| JP2005523942A (ja) | 2002-04-30 | 2005-08-11 | アヴィオル セラピューティクス インコーポレイテッド | 免疫療法のためのアデノウイルスベクター |
| DE10232322A1 (de) | 2002-07-16 | 2004-07-29 | Hahn, Gabriele, Dr. | Viral kodierte CxC determinieren den Gewebetropismus von HCMV |
| US7407744B2 (en) | 2003-07-25 | 2008-08-05 | The Regents Of The University Of California | Cytomegalovirus gene function and methods for developing antivirals, anti-CMV vaccines, and CMV-based vectors |
| EP2497831B1 (en) | 2004-05-25 | 2014-07-16 | Oregon Health and Science University | TB vaccination using HCMV-based vaccine vectors |
| EP1602676A1 (en) | 2004-06-01 | 2005-12-07 | SOLVAY (Société Anonyme) | Catalytic compositions |
| EP1799255A4 (en) | 2004-06-25 | 2008-10-01 | Medimmune Vaccines Inc | RECOMBINANT HUMANESE CYTOMEGALOVIRUS AND HETEROLOGIST ANTIGENS CONTAINING VACCINES |
| WO2006125983A1 (en) | 2005-05-23 | 2006-11-30 | Oxxon Therapeutics Ltd | Compositions for inducing an immune response against hepatitis b |
| BRPI0615400A2 (pt) | 2005-08-31 | 2011-05-17 | Genvec Inc | vacinas para malária baseadas em vetor adenoviral |
| US20100142823A1 (en) | 2007-03-07 | 2010-06-10 | Ze Wang | 2d partially parallel imaging with k-space surrounding neighbors based data reconstruction |
| US8883995B2 (en) | 2009-03-06 | 2014-11-11 | Icahn School Of Medicine At Mount Sinai | Live attenuated influenza virus vaccines comprising microRNA response elements |
| EA201270662A1 (ru) | 2009-12-23 | 2013-01-30 | 4-Антибоди Аг | Связывающие элементы для человеческого цитамегаловируса |
| WO2011093858A1 (en) | 2010-01-27 | 2011-08-04 | Oregon Health & Science University | Cytomegalovirus-based immunogenic preparations |
| AU2011230619C1 (en) | 2010-03-25 | 2016-06-23 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
| SG10201503450WA (en) | 2010-05-05 | 2015-06-29 | Thirion Christian | Vaccine against beta-herpesvirus infection and use thereof |
| TR201802741T4 (tr) | 2010-05-14 | 2018-03-21 | Univ Oregon Health & Science | Rekombinant hcmv ve rhcmv vektörleri ve bunların kullanımları. |
| HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
| DK2964769T3 (en) | 2013-03-05 | 2018-12-10 | Univ Oregon Health & Science | Cytomegalovirus vectors enabling control of T cell targeting |
| CN113528466B (zh) | 2014-07-16 | 2024-12-24 | 俄勒冈健康与科学大学 | 包含外源抗原的人巨细胞病毒 |
| EP3048114A1 (en) | 2015-01-22 | 2016-07-27 | Novartis AG | Cytomegalovirus antigens and uses thereof |
| JP6816031B2 (ja) | 2015-02-10 | 2021-01-20 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物 |
| CN108474003A (zh) | 2015-11-20 | 2018-08-31 | 俄勒冈健康与科学大学 | 包含微小rna识别元件的cmv载体 |
| CN109843321A (zh) | 2016-06-22 | 2019-06-04 | 国际艾滋病疫苗行动组织公司 | 作为结核病疫苗的重组巨细胞病毒载体 |
| US20200182884A1 (en) | 2016-06-27 | 2020-06-11 | Juno Therapeutics, Inc. | Method of identifying peptide epitopes, molecules that bind such epitopes and related uses |
| US10532099B2 (en) | 2016-10-18 | 2020-01-14 | Oregon Health & Science University | Cytomegalovirus vectors eliciting T cells restricted by major histocompatibility complex E molecules |
-
2016
- 2016-02-10 JP JP2017560883A patent/JP6816031B2/ja not_active Expired - Fee Related
- 2016-02-10 HK HK18106974.7A patent/HK1247638A1/zh unknown
- 2016-02-10 EP EP16749813.8A patent/EP3256595A4/en not_active Withdrawn
- 2016-02-10 MA MA041756A patent/MA41756A/fr unknown
- 2016-02-10 HK HK18113013.6A patent/HK1254041A1/zh unknown
- 2016-02-10 MX MX2017010027A patent/MX2017010027A/es unknown
- 2016-02-10 KR KR1020177025544A patent/KR20170136512A/ko not_active Ceased
- 2016-02-10 AU AU2016219317A patent/AU2016219317A1/en not_active Abandoned
- 2016-02-10 BR BR112017017092A patent/BR112017017092A2/pt not_active Application Discontinuation
- 2016-02-10 EP EP21205026.4A patent/EP4036239A1/en not_active Withdrawn
- 2016-02-10 CA CA2976245A patent/CA2976245A1/en not_active Abandoned
- 2016-02-10 EA EA201791806A patent/EA201791806A1/ru unknown
- 2016-02-10 CN CN201680014682.9A patent/CN108064304A/zh active Pending
- 2016-02-10 SG SG11201706454VA patent/SG11201706454VA/en unknown
- 2016-02-10 CN CN202111437865.0A patent/CN114317611A/zh active Pending
- 2016-02-10 WO PCT/US2016/017373 patent/WO2016130693A1/en not_active Ceased
- 2016-02-10 US US15/549,814 patent/US20180298404A1/en not_active Abandoned
-
2017
- 2017-08-09 IL IL253935A patent/IL253935B/en unknown
-
2020
- 2020-01-09 US US16/738,178 patent/US11091779B2/en not_active Expired - Fee Related
- 2020-12-23 JP JP2020213267A patent/JP2021121185A/ja active Pending
-
2022
- 2022-08-08 JP JP2022126096A patent/JP2022166122A/ja active Pending
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