JP2018509890A - 人工多能性幹細胞(iPSC)の生産を再プログラムする方法 - Google Patents
人工多能性幹細胞(iPSC)の生産を再プログラムする方法 Download PDFInfo
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- JP2018509890A JP2018509890A JP2017540262A JP2017540262A JP2018509890A JP 2018509890 A JP2018509890 A JP 2018509890A JP 2017540262 A JP2017540262 A JP 2017540262A JP 2017540262 A JP2017540262 A JP 2017540262A JP 2018509890 A JP2018509890 A JP 2018509890A
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- δ133p53β
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- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
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- C12N2510/00—Genetically modified cells
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- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurosurgery (AREA)
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- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
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- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305145 | 2015-01-30 | ||
| EP15305145.3 | 2015-01-30 | ||
| PCT/EP2016/052085 WO2016120493A1 (en) | 2015-01-30 | 2016-02-01 | Reprogramming method for producing induced pluripotent stem cells (ipsc) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018509890A true JP2018509890A (ja) | 2018-04-12 |
| JP2018509890A5 JP2018509890A5 (enExample) | 2019-03-14 |
Family
ID=52589314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540262A Pending JP2018509890A (ja) | 2015-01-30 | 2016-02-01 | 人工多能性幹細胞(iPSC)の生産を再プログラムする方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10767165B2 (enExample) |
| EP (1) | EP3250679B1 (enExample) |
| JP (1) | JP2018509890A (enExample) |
| WO (1) | WO2016120493A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022534295A (ja) * | 2019-05-30 | 2022-07-28 | イミュノルクス インターナショナル コーポレーション | ワクチン接種及び疾患治療法のための自己人工多能性幹細胞とのポックスウイルスの使用 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11845960B2 (en) | 2016-09-12 | 2023-12-19 | President And Fellows Of Harvard College | Transcription factors controlling differentiation of stem cells |
| WO2018064460A1 (en) * | 2016-09-30 | 2018-04-05 | Mayo Foundation For Medical Education And Research | Viral vectors for nuclear reprogramming |
| WO2018204262A1 (en) * | 2017-05-01 | 2018-11-08 | President And Fellows Of Harvard College | Transcription factors controlling differentiation of stem cells |
| GB2564437B (en) * | 2017-07-10 | 2020-11-04 | Univ Brunel | Method of testing a gene therapy vector using induced pluripotent stem cells |
| WO2019108894A1 (en) | 2017-12-01 | 2019-06-06 | President And Fellows Of Harvard College | Methods and compositions for the production of oligodendrocyte progenitor cells |
| US11788131B2 (en) | 2018-04-06 | 2023-10-17 | President And Fellows Of Harvard College | Methods of identifying combinations of transcription factors |
| GB201909975D0 (en) * | 2019-07-11 | 2019-08-28 | Babraham Inst | Novel reprogramming method |
| US20220273591A1 (en) * | 2019-07-26 | 2022-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for determining risk of developing insulin resistance |
| CN114736872A (zh) * | 2022-05-06 | 2022-07-12 | 中国科学院动物研究所 | 提高多能干细胞性能的组合物、方法及其应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012531606A (ja) * | 2009-06-30 | 2012-12-10 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス) | Δ133p53βを用いた転移癌を有する素因があると思われる被験体の検査方法 |
| JP2013541951A (ja) * | 2010-10-01 | 2013-11-21 | アメリカ合衆国 | p53アイソフォームによる幹細胞機能の操作 |
| JP2018506278A (ja) * | 2015-01-30 | 2018-03-08 | センター ナショナル ド ラ ルシェルシュ サイエンティフィーク | デルタ133p53ベータおよびデルタ133p53ガンマアイソフォームはがん幹細胞のバイオマーカーである |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2690554T3 (es) * | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| KR101606943B1 (ko) * | 2008-06-27 | 2016-03-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| WO2010033991A2 (en) * | 2008-09-22 | 2010-03-25 | Children's Medical Center Corporation | Detection of human somatic cell reprogramming |
| WO2011016588A1 (en) * | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
-
2016
- 2016-02-01 EP EP16702146.8A patent/EP3250679B1/en active Active
- 2016-02-01 JP JP2017540262A patent/JP2018509890A/ja active Pending
- 2016-02-01 US US15/547,212 patent/US10767165B2/en active Active
- 2016-02-01 WO PCT/EP2016/052085 patent/WO2016120493A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012531606A (ja) * | 2009-06-30 | 2012-12-10 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス) | Δ133p53βを用いた転移癌を有する素因があると思われる被験体の検査方法 |
| JP2013541951A (ja) * | 2010-10-01 | 2013-11-21 | アメリカ合衆国 | p53アイソフォームによる幹細胞機能の操作 |
| JP2018506278A (ja) * | 2015-01-30 | 2018-03-08 | センター ナショナル ド ラ ルシェルシュ サイエンティフィーク | デルタ133p53ベータおよびデルタ133p53ガンマアイソフォームはがん幹細胞のバイオマーカーである |
Non-Patent Citations (5)
| Title |
|---|
| ARSIC N. ET AL., STEM CELL REPORTS, vol. Vol.4 [Epub 2015 Mar 5], JPN6020011440, pages 531 - 540, ISSN: 0004240066 * |
| BOURDON J. ET AL., GENES & DEVELOPMENT, vol. 19 (2005), JPN6020011439, pages 2122 - 2137, ISSN: 0004446041 * |
| MAHERALI N. ET AL., CELL STEM CELL, vol. 3 (2008), JPN6020011438, pages 595 - 605, ISSN: 0004446042 * |
| MONTSERRAT N. ET AL., J. BIOL. CHEM., vol. Vol.287 No.29 (2012), JPN6021004853, pages 24131 - 24138, ISSN: 0004446043 * |
| POPOWSKI M. ET AL., STEM CELL REPORTS, vol. Vol.2 (2014), JPN6021004858, pages 26 - 35, ISSN: 0004446044 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022534295A (ja) * | 2019-05-30 | 2022-07-28 | イミュノルクス インターナショナル コーポレーション | ワクチン接種及び疾患治療法のための自己人工多能性幹細胞とのポックスウイルスの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3250679A1 (en) | 2017-12-06 |
| US10767165B2 (en) | 2020-09-08 |
| US20180023056A1 (en) | 2018-01-25 |
| WO2016120493A1 (en) | 2016-08-04 |
| EP3250679B1 (en) | 2020-08-19 |
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