JP2018509887A5 - - Google Patents
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- Publication number
- JP2018509887A5 JP2018509887A5 JP2017539548A JP2017539548A JP2018509887A5 JP 2018509887 A5 JP2018509887 A5 JP 2018509887A5 JP 2017539548 A JP2017539548 A JP 2017539548A JP 2017539548 A JP2017539548 A JP 2017539548A JP 2018509887 A5 JP2018509887 A5 JP 2018509887A5
- Authority
- JP
- Japan
- Prior art keywords
- hngal
- hngal mutein
- ang
- mutein
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15152826 | 2015-01-28 | ||
| EP15152826.2 | 2015-01-28 | ||
| PCT/EP2016/051657 WO2016120307A1 (en) | 2015-01-28 | 2016-01-27 | Novel proteins specific for angiogenesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018509887A JP2018509887A (ja) | 2018-04-12 |
| JP2018509887A5 true JP2018509887A5 (cg-RX-API-DMAC7.html) | 2019-03-07 |
| JP6839087B2 JP6839087B2 (ja) | 2021-03-03 |
Family
ID=52396588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017539548A Expired - Fee Related JP6839087B2 (ja) | 2015-01-28 | 2016-01-27 | 血管新生に特異的な新規のタンパク質 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10526382B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3250586B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6839087B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20170105609A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107207574A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016212087B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017015773A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2973640A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3250586T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX384075B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2720688C2 (cg-RX-API-DMAC7.html) |
| SG (2) | SG11201705278QA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016120307A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201704320B (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2564125C2 (ru) | 2009-12-07 | 2015-09-27 | Пирис Аг | Мутеины липокалина 2 человека (lcn2, hngal) с аффинностью для определенной мишени |
| EP2920202B1 (en) | 2012-11-19 | 2018-08-29 | Pieris Pharmaceuticals GmbH | Novel specific-binding polypeptides and uses thereof |
| SG10201912019WA (en) | 2014-05-22 | 2020-02-27 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| CA2973640A1 (en) | 2015-01-28 | 2016-08-04 | Rachida Siham Bel Aiba | Novel proteins specific for angiogenesis |
| DK3292137T3 (da) | 2015-05-04 | 2022-10-17 | Pieris Pharmaceuticals Gmbh | Proteiner specifikke for cd137 |
| BR112017020434A2 (pt) | 2015-05-04 | 2018-06-26 | Pieris Pharmaceuticals Gmbh | polipeptídeos de fusão, molécula de ácido nucleico, célula hospedeira, método para produzir um polipeptídeo de fusão, usos do polipeptídeo de fusão, métodos para ativar as vias de sinalização, para coestimular células, para induzir a proliferação de linfócitos t, para direcionar o agrupamento de cd137, para induzir uma resposta local de células t, para induzir uma resposta local de células nk e para induzir a produção de il-2 |
| MX390894B (es) | 2015-05-18 | 2025-03-21 | Pieris Pharmaceuticals Gmbh | Polipéptido de fusión anti-cáncer. |
| KR20180008649A (ko) | 2015-05-18 | 2018-01-24 | 피어이스 파마슈티컬즈 게엠베하 | 글리피칸-3(gpc3)에 대해 친화도를 갖는 인간 리포칼린 2의 뮤테인 |
| EA035586B1 (ru) * | 2015-11-30 | 2020-07-10 | Пиерис Острелиа Пти Лтд. | Новые антиангиогенные слитые белки |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
| JP7088454B2 (ja) | 2015-12-30 | 2022-06-21 | コディアック サイエンシーズ インコーポレイテッド | 抗体および抗体複合体 |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| US11633399B2 (en) | 2018-12-25 | 2023-04-25 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with compositions comprising an EGFR inhibitor |
| CA3127973A1 (en) * | 2019-03-29 | 2020-10-08 | Pieris Pharmaceuticals Gmbh | Inhaled administration of lipocalin muteins |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| AU2021285201A1 (en) | 2020-06-05 | 2022-11-24 | Pieris Pharmaceuticals Gmbh | Multimeric immunomodulator targeting 4-1BB |
| EP4215204A1 (en) * | 2022-01-24 | 2023-07-26 | Universitat Pompeu Fabra | Human neutrophil gelatinase-associated lipocalin derived from recombinant bacteria and uses thereof |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3779221D1 (de) | 1986-08-19 | 1992-06-25 | Genentech Inc | Einrichtung und dispersion zum intrapulmonalen eingeben von polypeptidwuchsstoffen und -zytokinen. |
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| ES2245780T3 (es) | 1994-05-18 | 2006-01-16 | Nektar Therapeutics | Metodos y composiciones para la formulacion de interferones como un polvo seco. |
| DE4417598A1 (de) | 1994-05-19 | 1995-12-14 | Max Planck Gesellschaft | Verwendung des Tetracyclinpromotors zur stringent regulierten Produktion von rekombinanten Proteinen in prokaryontischen Zellen |
| AU5132096A (en) | 1995-01-30 | 1996-08-21 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| WO1998016873A1 (en) | 1996-10-14 | 1998-04-23 | Firm Forsat Ltd. | Method for preparing dispersions of chromogenic components |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| KR20010052622A (ko) | 1998-06-08 | 2001-06-25 | 프리돌린 클라우스너, 롤란드 비. 보레르 | 만성 씨형 간염을 치료하기 위한 폴리에틸렌글리콜-인터페론-알파 및 리바비린의 용도 |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| DE19926068C1 (de) | 1999-06-08 | 2001-01-11 | Arne Skerra | Muteine des Bilin-Bindungsproteins |
| US7211395B2 (en) | 2001-03-09 | 2007-05-01 | Dyax Corp. | Serum albumin binding moieties |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| AU2001298053A1 (en) | 2001-09-27 | 2003-04-14 | Pieris Proteolab Ag | Muteins of apolipoprotein D |
| US7691970B2 (en) | 2003-08-25 | 2010-04-06 | Pieris Ag | Muteins of a bilin-binding protein with affinity for a given target |
| AU2003275958A1 (en) | 2003-08-25 | 2005-03-10 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| JP2007284351A (ja) | 2004-07-27 | 2007-11-01 | Osaka Bioscience Institute | アミロイド蛋白質の凝集を抑制する物質とその作用 |
| US7892827B2 (en) | 2004-11-26 | 2011-02-22 | Pieris Ag | Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4) |
| WO2007038619A2 (en) | 2005-09-27 | 2007-04-05 | Amunix, Inc. | Proteinaceous pharmaceuticals and uses thereof |
| NO347649B1 (no) | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| CA2702611A1 (en) | 2007-10-19 | 2009-04-23 | Abbott Laboratories | Immunoassays and kits for the detection of ngal |
| SG172737A1 (en) * | 2008-01-30 | 2011-07-28 | Pieris Ag | Muteins of tear lipocalin having affinity to human c-met receptor tyrosine kinaseand methods for obtaining the same |
| US8420051B2 (en) * | 2008-06-24 | 2013-04-16 | Technische Universitaet Meunchen | Muteins of hNGAL and related proteins with affinity for a given target |
| US8133979B2 (en) * | 2008-12-16 | 2012-03-13 | Hoffmann-La Roche Inc. | Antibodies against human angiopoietin 2 |
| RU2564125C2 (ru) * | 2009-12-07 | 2015-09-27 | Пирис Аг | Мутеины липокалина 2 человека (lcn2, hngal) с аффинностью для определенной мишени |
| SG187695A1 (en) | 2010-08-16 | 2013-03-28 | Pieris Ag | Binding proteins for hepcidin |
| US9260492B2 (en) | 2010-11-15 | 2016-02-16 | Pieris Ag | Muteins of human lipocalin 2 with affinity for glypican-3 (GPC-3) |
| WO2013174783A1 (en) * | 2012-05-23 | 2013-11-28 | Pieris Ag | Lipocalin muteins with binding-affinity for glypican-3 (gpc-3) and use of lipocalin muteins for target-specific delivery to cells expressing gpc-3 |
| EP2920202B1 (en) * | 2012-11-19 | 2018-08-29 | Pieris Pharmaceuticals GmbH | Novel specific-binding polypeptides and uses thereof |
| GB201223053D0 (en) * | 2012-12-20 | 2013-02-06 | Medical Res Council | Receptor |
| CA2973640A1 (en) | 2015-01-28 | 2016-08-04 | Rachida Siham Bel Aiba | Novel proteins specific for angiogenesis |
| CA2976687A1 (en) | 2015-02-18 | 2016-08-25 | Sanofi | Novel proteins specific for pyoverdine and pyochelin |
| DK3292137T3 (da) | 2015-05-04 | 2022-10-17 | Pieris Pharmaceuticals Gmbh | Proteiner specifikke for cd137 |
| KR20180008649A (ko) | 2015-05-18 | 2018-01-24 | 피어이스 파마슈티컬즈 게엠베하 | 글리피칸-3(gpc3)에 대해 친화도를 갖는 인간 리포칼린 2의 뮤테인 |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
-
2016
- 2016-01-27 CA CA2973640A patent/CA2973640A1/en active Pending
- 2016-01-27 JP JP2017539548A patent/JP6839087B2/ja not_active Expired - Fee Related
- 2016-01-27 MX MX2017009767A patent/MX384075B/es unknown
- 2016-01-27 BR BR112017015773-0A patent/BR112017015773A2/pt not_active Application Discontinuation
- 2016-01-27 CN CN201680007089.1A patent/CN107207574A/zh active Pending
- 2016-01-27 EP EP16703451.1A patent/EP3250586B1/en active Active
- 2016-01-27 SG SG11201705278QA patent/SG11201705278QA/en unknown
- 2016-01-27 US US15/546,609 patent/US10526382B2/en active Active
- 2016-01-27 AU AU2016212087A patent/AU2016212087B2/en not_active Ceased
- 2016-01-27 DK DK16703451.1T patent/DK3250586T3/da active
- 2016-01-27 WO PCT/EP2016/051657 patent/WO2016120307A1/en not_active Ceased
- 2016-01-27 SG SG10201906859PA patent/SG10201906859PA/en unknown
- 2016-01-27 RU RU2017128105A patent/RU2720688C2/ru active
- 2016-01-27 KR KR1020177023448A patent/KR20170105609A/ko not_active Ceased
-
2017
- 2017-06-26 ZA ZA2017/04320A patent/ZA201704320B/en unknown
-
2019
- 2019-11-13 US US16/682,499 patent/US11034738B2/en not_active Expired - Fee Related
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