JP2018508225A5 - - Google Patents
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- JP2018508225A5 JP2018508225A5 JP2017549041A JP2017549041A JP2018508225A5 JP 2018508225 A5 JP2018508225 A5 JP 2018508225A5 JP 2017549041 A JP2017549041 A JP 2017549041A JP 2017549041 A JP2017549041 A JP 2017549041A JP 2018508225 A5 JP2018508225 A5 JP 2018508225A5
- Authority
- JP
- Japan
- Prior art keywords
- lactobacillus
- vaginalis
- specific
- target
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000523 sample Substances 0.000 claims description 286
- 241000186660 Lactobacillus Species 0.000 claims description 248
- 229940039696 lactobacillus Drugs 0.000 claims description 248
- 239000002773 nucleotide Substances 0.000 claims description 243
- 125000003729 nucleotide group Chemical group 0.000 claims description 243
- 230000003321 amplification Effects 0.000 claims description 241
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 241
- 238000000034 method Methods 0.000 claims description 194
- 241000186610 Lactobacillus sp. Species 0.000 claims description 109
- 241000853331 Eggerella Species 0.000 claims description 99
- 108020004707 nucleic acids Proteins 0.000 claims description 89
- 150000007523 nucleic acids Chemical class 0.000 claims description 89
- 102000039446 nucleic acids Human genes 0.000 claims description 89
- 238000001514 detection method Methods 0.000 claims description 72
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims description 38
- 241000207201 Gardnerella vaginalis Species 0.000 claims description 30
- 208000037009 Vaginitis bacterial Diseases 0.000 claims description 26
- 238000003556 assay Methods 0.000 claims description 20
- 108020004465 16S ribosomal RNA Proteins 0.000 claims description 18
- 238000000338 in vitro Methods 0.000 claims description 11
- 230000008685 targeting Effects 0.000 claims description 9
- 241000894007 species Species 0.000 claims description 8
- 108091093088 Amplicon Proteins 0.000 claims description 7
- 230000001580 bacterial effect Effects 0.000 claims description 7
- 230000002538 fungal effect Effects 0.000 claims description 4
- 240000000178 Monochoria vaginalis Species 0.000 claims description 2
- 229940035901 lactobacillus sp Drugs 0.000 claims 2
- 241001394620 Eggerthella sp. Species 0.000 claims 1
- 238000011895 specific detection Methods 0.000 description 101
- 239000007850 fluorescent dye Substances 0.000 description 12
- 241001657509 Eggerthella Species 0.000 description 7
- 238000011901 isothermal amplification Methods 0.000 description 4
- 230000001404 mediated effect Effects 0.000 description 4
- 238000013518 transcription Methods 0.000 description 4
- 230000035897 transcription Effects 0.000 description 4
- 238000011269 treatment regimen Methods 0.000 description 4
- 241000207202 Gardnerella Species 0.000 description 1
- 241000218492 Lactobacillus crispatus Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020190284A JP6970268B2 (ja) | 2015-03-16 | 2020-11-16 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
| JP2021176198A JP2022025106A (ja) | 2015-03-16 | 2021-10-28 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562133881P | 2015-03-16 | 2015-03-16 | |
| US62/133,881 | 2015-03-16 | ||
| US201562168688P | 2015-05-29 | 2015-05-29 | |
| US201562168405P | 2015-05-29 | 2015-05-29 | |
| US62/168,688 | 2015-05-29 | ||
| US62/168,405 | 2015-05-29 | ||
| PCT/US2016/022628 WO2016149357A1 (en) | 2015-03-16 | 2016-03-16 | Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020190284A Division JP6970268B2 (ja) | 2015-03-16 | 2020-11-16 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018508225A JP2018508225A (ja) | 2018-03-29 |
| JP2018508225A5 true JP2018508225A5 (enExample) | 2019-04-11 |
| JP6796593B2 JP6796593B2 (ja) | 2020-12-09 |
Family
ID=56919495
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017549041A Active JP6796593B2 (ja) | 2015-03-16 | 2016-03-16 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
| JP2020190284A Active JP6970268B2 (ja) | 2015-03-16 | 2020-11-16 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
| JP2021176198A Pending JP2022025106A (ja) | 2015-03-16 | 2021-10-28 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020190284A Active JP6970268B2 (ja) | 2015-03-16 | 2020-11-16 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
| JP2021176198A Pending JP2022025106A (ja) | 2015-03-16 | 2021-10-28 | 細菌核酸を検出し細菌性膣炎を診断するための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10550438B2 (enExample) |
| EP (2) | EP3910075B1 (enExample) |
| JP (3) | JP6796593B2 (enExample) |
| CN (1) | CN107429297A (enExample) |
| AU (2) | AU2016233298B2 (enExample) |
| CA (1) | CA2977821A1 (enExample) |
| WO (1) | WO2016149357A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016233298B2 (en) * | 2015-03-16 | 2021-09-02 | Gen-Probe Incorporated | Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
| EP3663410A4 (en) * | 2017-07-31 | 2020-07-08 | Toppan Printing Co., Ltd. | NUCLEIC ACID DETECTION METHOD AND DETECTION REAGENT |
| AU2019274350B2 (en) * | 2018-05-23 | 2022-04-07 | Kobiolabs, Inc. | Lactobacillus crispatus KBL693 strain and use thereof |
| WO2020033440A1 (en) * | 2018-08-10 | 2020-02-13 | The Regents Of The University Of California | Methods and compositions for treating and preventing inflammatory diseases |
| KR102868953B1 (ko) * | 2018-08-24 | 2025-10-13 | 젠-프로브 인코포레이티드 | 세균성 핵산을 검출하고 세균성 질염을 진단하기 위한 조성물 및 방법 |
| WO2020166708A1 (ja) * | 2019-02-15 | 2020-08-20 | コンビ株式会社 | 新規乳酸菌およびそれを含有する組成物 |
| CN110283921A (zh) * | 2019-07-12 | 2019-09-27 | 中生方政生物技术股份有限公司 | 加德纳杆菌、白色念珠菌双重检测的引物、探针组、试剂盒及检测方法 |
| US20220205020A1 (en) * | 2020-12-30 | 2022-06-30 | Roche Molecular Systems, Inc. | Compositions and methods for detection of bacteria and fungi associated with bacterial and candida vaginosis |
| JP7734205B2 (ja) * | 2021-04-02 | 2025-09-04 | 宝山鋼鉄股▲分▼有限公司 | 引張強度≧１１８０ＭＰａの低炭素低合金Ｑ＆Ｐ鋼または溶融亜鉛めっきＱ＆Ｐ鋼及びその製造方法 |
| EP4289964A4 (en) | 2022-04-18 | 2024-10-09 | Beijing OriginPoly Bio-Tec Co., Ltd. | PRIMER-PROBE COMBINATION AND KIT FOR VAGINAL MICROECOSYSTEM DETECTION |
| CN114480694B (zh) * | 2022-04-18 | 2022-06-17 | 北京起源聚禾生物科技有限公司 | 阴道微生态检测引物探针组合及试剂盒 |
| WO2024006762A1 (en) * | 2022-06-27 | 2024-01-04 | The Uab Research Foundation | Nucleic acid probes and their uses for the detection of prevotella bivia |
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| AU2016233298B2 (en) * | 2015-03-16 | 2021-09-02 | Gen-Probe Incorporated | Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
| KR102868953B1 (ko) * | 2018-08-24 | 2025-10-13 | 젠-프로브 인코포레이티드 | 세균성 핵산을 검출하고 세균성 질염을 진단하기 위한 조성물 및 방법 |
-
2016
- 2016-03-16 AU AU2016233298A patent/AU2016233298B2/en active Active
- 2016-03-16 EP EP21174621.9A patent/EP3910075B1/en active Active
- 2016-03-16 CA CA2977821A patent/CA2977821A1/en active Pending
- 2016-03-16 WO PCT/US2016/022628 patent/WO2016149357A1/en not_active Ceased
- 2016-03-16 CN CN201680018451.5A patent/CN107429297A/zh active Pending
- 2016-03-16 US US15/557,912 patent/US10550438B2/en active Active
- 2016-03-16 EP EP16765647.9A patent/EP3271484B1/en active Active
- 2016-03-16 JP JP2017549041A patent/JP6796593B2/ja active Active
-
2019
- 2019-12-11 US US16/711,194 patent/US11268156B2/en active Active
-
2020
- 2020-11-16 JP JP2020190284A patent/JP6970268B2/ja active Active
-
2021
- 2021-05-24 US US17/327,829 patent/US12031187B2/en active Active
- 2021-10-28 JP JP2021176198A patent/JP2022025106A/ja active Pending
- 2021-12-02 AU AU2021277704A patent/AU2021277704B2/en active Active
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