JP2018507033A5 - - Google Patents
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- JP2018507033A5 JP2018507033A5 JP2017540823A JP2017540823A JP2018507033A5 JP 2018507033 A5 JP2018507033 A5 JP 2018507033A5 JP 2017540823 A JP2017540823 A JP 2017540823A JP 2017540823 A JP2017540823 A JP 2017540823A JP 2018507033 A5 JP2018507033 A5 JP 2018507033A5
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- Prior art keywords
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- Prior art date
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- 239000000203 mixture Substances 0.000 claims description 218
- 206010052428 Wound Diseases 0.000 claims description 86
- 208000027418 Wounds and injury Diseases 0.000 claims description 86
- 239000000835 fiber Substances 0.000 claims description 82
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 66
- 102000004190 Enzymes Human genes 0.000 claims description 52
- 108090000790 Enzymes Proteins 0.000 claims description 52
- 229940088598 enzyme Drugs 0.000 claims description 52
- 239000000758 substrate Substances 0.000 claims description 49
- 239000003125 aqueous solvent Substances 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 22
- 239000000126 substance Substances 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 208000015181 infectious disease Diseases 0.000 claims description 11
- 230000000813 microbial effect Effects 0.000 claims description 11
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 10
- 230000002265 prevention Effects 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- 238000001804 debridement Methods 0.000 claims description 6
- 230000000845 anti-microbial effect Effects 0.000 claims description 5
- 230000008467 tissue growth Effects 0.000 claims description 5
- 238000004332 deodorization Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 230000000638 stimulation Effects 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 230000032770 biofilm formation Effects 0.000 claims description 3
- 238000001523 electrospinning Methods 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 239000004366 Glucose oxidase Substances 0.000 claims description 2
- 108010015776 Glucose oxidase Proteins 0.000 claims description 2
- 229940116332 glucose oxidase Drugs 0.000 claims description 2
- 235000019420 glucose oxidase Nutrition 0.000 claims description 2
- 239000002121 nanofiber Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 102000003992 Peroxidases Human genes 0.000 claims 3
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 3
- 239000007921 spray Substances 0.000 claims 3
- 230000001954 sterilising effect Effects 0.000 claims 3
- 230000000844 anti-bacterial effect Effects 0.000 claims 2
- 210000002850 nasal mucosa Anatomy 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000003595 mist Substances 0.000 claims 1
- MEUIIHOXOWVKNP-UHFFFAOYSA-N phosphanylformic acid Chemical compound OC(P)=O MEUIIHOXOWVKNP-UHFFFAOYSA-N 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 239000004632 polycaprolactone Substances 0.000 claims 1
- 239000004633 polyglycolic acid Substances 0.000 claims 1
- 239000004626 polylactic acid Substances 0.000 claims 1
- 238000005086 pumping Methods 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 235000012907 honey Nutrition 0.000 description 16
- 239000005445 natural material Substances 0.000 description 13
- 238000013268 sustained release Methods 0.000 description 12
- 239000012730 sustained-release form Substances 0.000 description 12
- 239000000080 wetting agent Substances 0.000 description 9
- 239000000463 material Substances 0.000 description 8
- 239000003906 humectant Substances 0.000 description 6
- 230000002255 enzymatic effect Effects 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000001877 deodorizing effect Effects 0.000 description 2
- -1 drying aid Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 238000010899 nucleation Methods 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 241000588626 Acinetobacter baumannii Species 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 239000006057 Non-nutritive feed additive Substances 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 238000002663 nebulization Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201501805A GB201501805D0 (en) | 2015-02-03 | 2015-02-03 | Antimicrobial fibers |
| GB1501805.4 | 2015-02-03 | ||
| GB1508311.6 | 2015-05-14 | ||
| GBGB1508311.6A GB201508311D0 (en) | 2015-05-14 | 2015-05-14 | Antimicrobial fibers and compositions |
| GB1509652.2 | 2015-06-03 | ||
| GBGB1509652.2A GB201509652D0 (en) | 2015-06-03 | 2015-06-03 | Antimicrobial fibers and compositions |
| GB1513046.1 | 2015-07-23 | ||
| GBGB1513046.1A GB201513046D0 (en) | 2015-07-23 | 2015-07-23 | Antimicrobial fibers and compositions |
| GBGB1518258.7A GB201518258D0 (en) | 2015-10-15 | 2015-10-15 | Antimicrobial fibers and compositions |
| GB1518258.7 | 2015-10-15 | ||
| GBGB1519484.8A GB201519484D0 (en) | 2015-11-04 | 2015-11-04 | Antimicrobial fibers and compositions |
| GB1519484.8 | 2015-11-04 | ||
| GBGB1520771.5A GB201520771D0 (en) | 2015-11-24 | 2015-11-24 | Antimicrobial fibers and compositions |
| GB1520771.5 | 2015-11-24 | ||
| GB1522450.4 | 2015-12-18 | ||
| GBGB1522450.4A GB201522450D0 (en) | 2015-12-18 | 2015-12-18 | Antimicrobial Fibers and Compositions |
| PCT/GB2016/050253 WO2016124926A1 (en) | 2015-02-03 | 2016-02-03 | Antimicrobial fibers and compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025152A Division JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018507033A JP2018507033A (ja) | 2018-03-15 |
| JP2018507033A5 true JP2018507033A5 (https=) | 2019-02-28 |
Family
ID=55588312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540823A Pending JP2018507033A (ja) | 2015-02-03 | 2016-02-03 | 抗微生物繊維及び組成物 |
| JP2019025152A Pending JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025152A Pending JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180023217A1 (https=) |
| EP (2) | EP3858392B1 (https=) |
| JP (2) | JP2018507033A (https=) |
| CN (1) | CN107708752A (https=) |
| AU (1) | AU2016214119B2 (https=) |
| BR (1) | BR112017016545A2 (https=) |
| CA (1) | CA2975197A1 (https=) |
| GB (2) | GB2573068B (https=) |
| HK (1) | HK1246699A1 (https=) |
| WO (1) | WO2016124926A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| JP5833134B2 (ja) | 2010-12-08 | 2015-12-16 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 創傷部位から滲出液を除去するための方法およびシステム |
| CN103347561B (zh) | 2010-12-08 | 2016-09-07 | 康沃特克科技公司 | 用于评估伤口分泌液的集成系统 |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| WO2014096843A2 (en) | 2012-12-20 | 2014-06-26 | Convatec Technologies Inc. | Processing of chemically modified cellulosic fibres |
| NZ726323A (en) | 2014-04-30 | 2020-02-28 | Matoke Holdings Ltd | Antimicrobial compositions |
| ES2964692T3 (es) | 2015-04-28 | 2024-04-09 | Convatec Technologies Inc | Nanofibras antibacterianas |
| MA42910A (fr) * | 2015-07-23 | 2018-05-30 | Matoke Holdings Ltd | Compositions antimicrobiennes et formulations libérant du peroxyde d'hydrogène |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| SG11201808488XA (en) | 2016-03-30 | 2018-10-30 | Convatec Technologies Inc | Detecting microbial infections in wounds |
| CA3019436A1 (en) | 2016-03-30 | 2017-10-05 | Qualizyme Diagnostics Gmbh & Co Kg | Detecting microbial infection in wounds |
| US20200323963A1 (en) * | 2016-04-12 | 2020-10-15 | Matoke Holdings Limited | Antimicrobial fibers and compositions |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| EP3871645B1 (en) | 2016-07-08 | 2022-05-04 | ConvaTec Technologies Inc. | Flexible negative pressure system |
| JP2019525799A (ja) | 2016-07-08 | 2019-09-12 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 流体収集装置 |
| ES2912094T3 (es) | 2016-07-08 | 2022-05-24 | Convatec Technologies Inc | Detección de flujo de fluidos |
| BR112019006932A2 (pt) | 2016-10-06 | 2019-07-02 | Matoke Holdings Limited | composições antimicrobianas |
| WO2018065789A1 (en) | 2016-10-06 | 2018-04-12 | Matoke Holdings Limited | Antimicrobial compositions |
| WO2018107277A1 (en) * | 2016-12-12 | 2018-06-21 | Luong John Ha Thanh | Antibacterial products and processes for preparing antibacterial products from maple syrup |
| GB201716986D0 (en) | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| EP4360666A3 (en) | 2017-11-16 | 2024-05-08 | ConvaTec Limited | Fluid collection apparatus |
| GB201805996D0 (en) * | 2018-04-11 | 2018-05-23 | Matoke Holdings Ltd | Tissue scaffold |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| US20220175829A1 (en) | 2019-03-27 | 2022-06-09 | Matoke Holdings Limited | Antimicrobial Compositions |
| SG11202112292QA (en) | 2019-06-03 | 2021-12-30 | Convatec Ltd | Methods and devices to disrupt and contain pathogens |
| CN110353883A (zh) * | 2019-07-10 | 2019-10-22 | 重庆市人民医院 | 用于治疗褥疮的复合敷料层及带有复合敷料层的褥疮贴 |
| CN110496525A (zh) * | 2019-08-30 | 2019-11-26 | 山东多芬农业有限公司 | 空气净化剂及其制备和使用方法 |
| IL270762B (en) * | 2019-11-19 | 2021-10-31 | Sion Biotext Medical Ltd | Wound dressing comprising a combination of hydrogel and honey, method of preparation and uses thereof |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| EP4329831A1 (en) | 2020-03-16 | 2024-03-06 | Matoke Holdings Limited | Antimicrobial compositions |
| GB202106320D0 (en) | 2021-05-04 | 2021-06-16 | Matoke Holdings Ltd | Antimicrobial dressing |
| CN114732799B (zh) * | 2022-03-29 | 2023-09-22 | 南京大学 | 一种自供电的无载药抗菌贴片 |
| GB202210839D0 (en) | 2022-07-25 | 2022-09-07 | Matoke Holdings Ltd | Antimicrobial compositions |
| GB202309435D0 (en) | 2023-06-22 | 2023-08-09 | Matoke Holdings Ltd | Antimicrobial device |
| WO2025012618A1 (en) | 2023-07-07 | 2025-01-16 | Matoke Holdings Limited | Antimicrobial compositions |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1987893A (en) | 1931-03-26 | 1935-01-15 | Cornell Universlty | Honey process and product |
| EP0236610A1 (en) * | 1986-03-13 | 1987-09-16 | Laclede Professional Products, Inc. | Enzymatic bandages and pads |
| US4576817A (en) * | 1984-06-07 | 1986-03-18 | Laclede Professional Products, Inc. | Enzymatic bandages and pads |
| EP0563250A1 (en) * | 1990-12-19 | 1993-10-06 | Allergan, Inc. | Compositions and methods for contact lens disinfecting |
| CA2309500C (en) * | 1997-11-05 | 2012-04-17 | Koppert B.V. | Pesticide against plant-pathogenic micro-organisms |
| US6214339B1 (en) * | 2000-01-12 | 2001-04-10 | Michael A. Pellico | Di-enzymatic treatment of outer ear infection in dogs and cats |
| GB2382527A (en) * | 2001-12-03 | 2003-06-04 | Acordis Speciality Fibres Ltd | Wound dressings |
| ATE329628T1 (de) * | 2002-04-24 | 2006-07-15 | Insense Ltd | Wundauflage enthaltend ein oxidoreduktase-enzym in hydratiertem zustand |
| US20060142684A1 (en) * | 2003-04-11 | 2006-06-29 | Shanbrom Technologies, Llc | Oxygen releasing material |
| CA2574773A1 (en) * | 2004-07-22 | 2006-02-02 | Allan D. Pronovost | Compositions and methods for treating excessive bleeding |
| BE1017155A3 (nl) * | 2006-06-01 | 2008-03-04 | Sanomedical Bvba | Wondverzorgingsproduct. |
| GB0619786D0 (en) * | 2006-10-06 | 2006-11-15 | Inst Of Technology Sligo | An antimicrobial and immunostimulatory system |
| JP5337701B2 (ja) * | 2006-10-10 | 2013-11-06 | ラクリード、インコーポレイテッド | ペルオキシド生成酵素及びペルオキシダーゼを使用した膣疾患の治療のための方法及び組成物 |
| WO2008049251A1 (de) | 2006-10-23 | 2008-05-02 | Schoeller Textil Ag | Mikrobizide nano- und mesopolymerfasern aus polymeren und honig für textile anwendungen |
| BE1017344A3 (nl) * | 2006-10-27 | 2008-06-03 | Cnci Bvba | Methode voor het steriliseren van ruwe, onverhitte honing, preparaat voor wondverzorging op basis van honing en een wondverzorging behandelingsproduct. |
| US8512731B2 (en) * | 2007-11-13 | 2013-08-20 | Medtronic Minimed, Inc. | Antimicrobial coatings for medical devices and methods for making and using them |
| US20110111012A1 (en) | 2009-11-12 | 2011-05-12 | Hemcon Medical Technologies, Inc. | Nanomaterial wound dressing assembly |
| WO2012030231A1 (en) * | 2010-08-30 | 2012-03-08 | Comvita New Zealand Limited | Antifungal composition |
| EP2510944A1 (en) * | 2011-04-15 | 2012-10-17 | National University of Ireland, Galway | Treatment of bacterial infections |
| TWI636799B (zh) * | 2012-05-14 | 2018-10-01 | 日商帝人股份有限公司 | 滅菌組成物 |
| US20150030688A1 (en) * | 2013-07-25 | 2015-01-29 | Saint Louis University | Honey and growth factor eluting scaffold for wound healing and tissue engineering |
| NZ726323A (en) * | 2014-04-30 | 2020-02-28 | Matoke Holdings Ltd | Antimicrobial compositions |
| JP6861151B2 (ja) * | 2014-08-05 | 2021-04-21 | ザ ユニバーシティ オブ メンフィス | 骨および軟組織の治癒および再生を向上させるための組成物および方法 |
| CN107847527A (zh) * | 2014-11-24 | 2018-03-27 | 玛托克控股有限公司 | 微生物感染的预防和治疗 |
-
2016
- 2016-02-03 BR BR112017016545A patent/BR112017016545A2/pt active Search and Examination
- 2016-02-03 CA CA2975197A patent/CA2975197A1/en not_active Abandoned
- 2016-02-03 HK HK18106171.8A patent/HK1246699A1/zh unknown
- 2016-02-03 US US15/547,972 patent/US20180023217A1/en active Pending
- 2016-02-03 EP EP20212485.5A patent/EP3858392B1/en active Active
- 2016-02-03 GB GB1908998.6A patent/GB2573068B/en active Active
- 2016-02-03 GB GB1711217.8A patent/GB2550301B/en active Active
- 2016-02-03 JP JP2017540823A patent/JP2018507033A/ja active Pending
- 2016-02-03 AU AU2016214119A patent/AU2016214119B2/en active Active
- 2016-02-03 EP EP16711333.1A patent/EP3253424B1/en active Active
- 2016-02-03 CN CN201680020338.0A patent/CN107708752A/zh active Pending
- 2016-02-03 WO PCT/GB2016/050253 patent/WO2016124926A1/en not_active Ceased
-
2019
- 2019-02-15 JP JP2019025152A patent/JP2019080985A/ja active Pending
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