JP2018507033A5 - - Google Patents
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- JP2018507033A5 JP2018507033A5 JP2017540823A JP2017540823A JP2018507033A5 JP 2018507033 A5 JP2018507033 A5 JP 2018507033A5 JP 2017540823 A JP2017540823 A JP 2017540823A JP 2017540823 A JP2017540823 A JP 2017540823A JP 2018507033 A5 JP2018507033 A5 JP 2018507033A5
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- Prior art keywords
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- 239000000203 mixture Substances 0.000 claims description 218
- 206010052428 Wound Diseases 0.000 claims description 86
- 208000027418 Wounds and injury Diseases 0.000 claims description 86
- 239000000835 fiber Substances 0.000 claims description 82
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 66
- 102000004190 Enzymes Human genes 0.000 claims description 52
- 108090000790 Enzymes Proteins 0.000 claims description 52
- 229940088598 enzyme Drugs 0.000 claims description 52
- 239000000758 substrate Substances 0.000 claims description 49
- 239000003125 aqueous solvent Substances 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 22
- 239000000126 substance Substances 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 208000015181 infectious disease Diseases 0.000 claims description 11
- 230000000813 microbial effect Effects 0.000 claims description 11
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 10
- 230000002265 prevention Effects 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- 238000001804 debridement Methods 0.000 claims description 6
- 230000000845 anti-microbial effect Effects 0.000 claims description 5
- 230000008467 tissue growth Effects 0.000 claims description 5
- 238000004332 deodorization Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 230000000638 stimulation Effects 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 230000032770 biofilm formation Effects 0.000 claims description 3
- 238000001523 electrospinning Methods 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 239000004366 Glucose oxidase Substances 0.000 claims description 2
- 108010015776 Glucose oxidase Proteins 0.000 claims description 2
- 229940116332 glucose oxidase Drugs 0.000 claims description 2
- 235000019420 glucose oxidase Nutrition 0.000 claims description 2
- 239000002121 nanofiber Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 102000003992 Peroxidases Human genes 0.000 claims 3
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 3
- 239000007921 spray Substances 0.000 claims 3
- 230000001954 sterilising effect Effects 0.000 claims 3
- 230000000844 anti-bacterial effect Effects 0.000 claims 2
- 210000002850 nasal mucosa Anatomy 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000003595 mist Substances 0.000 claims 1
- MEUIIHOXOWVKNP-UHFFFAOYSA-N phosphanylformic acid Chemical compound OC(P)=O MEUIIHOXOWVKNP-UHFFFAOYSA-N 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 239000004632 polycaprolactone Substances 0.000 claims 1
- 239000004633 polyglycolic acid Substances 0.000 claims 1
- 239000004626 polylactic acid Substances 0.000 claims 1
- 238000005086 pumping Methods 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 235000012907 honey Nutrition 0.000 description 16
- 239000005445 natural material Substances 0.000 description 13
- 238000013268 sustained release Methods 0.000 description 12
- 239000012730 sustained-release form Substances 0.000 description 12
- 239000000080 wetting agent Substances 0.000 description 9
- 239000000463 material Substances 0.000 description 8
- 239000003906 humectant Substances 0.000 description 6
- 230000002255 enzymatic effect Effects 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000001877 deodorizing effect Effects 0.000 description 2
- -1 drying aid Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 238000010899 nucleation Methods 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 241000588626 Acinetobacter baumannii Species 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 239000006057 Non-nutritive feed additive Substances 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 238000002663 nebulization Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201501805A GB201501805D0 (en) | 2015-02-03 | 2015-02-03 | Antimicrobial fibers |
| GB1501805.4 | 2015-02-03 | ||
| GBGB1508311.6A GB201508311D0 (en) | 2015-05-14 | 2015-05-14 | Antimicrobial fibers and compositions |
| GB1508311.6 | 2015-05-14 | ||
| GB1509652.2 | 2015-06-03 | ||
| GBGB1509652.2A GB201509652D0 (en) | 2015-06-03 | 2015-06-03 | Antimicrobial fibers and compositions |
| GB1513046.1 | 2015-07-23 | ||
| GBGB1513046.1A GB201513046D0 (en) | 2015-07-23 | 2015-07-23 | Antimicrobial fibers and compositions |
| GBGB1518258.7A GB201518258D0 (en) | 2015-10-15 | 2015-10-15 | Antimicrobial fibers and compositions |
| GB1518258.7 | 2015-10-15 | ||
| GB1519484.8 | 2015-11-04 | ||
| GBGB1519484.8A GB201519484D0 (en) | 2015-11-04 | 2015-11-04 | Antimicrobial fibers and compositions |
| GB1520771.5 | 2015-11-24 | ||
| GBGB1520771.5A GB201520771D0 (en) | 2015-11-24 | 2015-11-24 | Antimicrobial fibers and compositions |
| GBGB1522450.4A GB201522450D0 (en) | 2015-12-18 | 2015-12-18 | Antimicrobial Fibers and Compositions |
| GB1522450.4 | 2015-12-18 | ||
| PCT/GB2016/050253 WO2016124926A1 (en) | 2015-02-03 | 2016-02-03 | Antimicrobial fibers and compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025152A Division JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018507033A JP2018507033A (ja) | 2018-03-15 |
| JP2018507033A5 true JP2018507033A5 (https=) | 2019-02-28 |
Family
ID=55588312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540823A Pending JP2018507033A (ja) | 2015-02-03 | 2016-02-03 | 抗微生物繊維及び組成物 |
| JP2019025152A Pending JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025152A Pending JP2019080985A (ja) | 2015-02-03 | 2019-02-15 | 抗微生物繊維及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180023217A1 (https=) |
| EP (2) | EP3253424B1 (https=) |
| JP (2) | JP2018507033A (https=) |
| CN (1) | CN107708752A (https=) |
| AU (1) | AU2016214119B2 (https=) |
| BR (1) | BR112017016545A2 (https=) |
| CA (1) | CA2975197A1 (https=) |
| GB (2) | GB2573068B (https=) |
| HK (1) | HK1246699A1 (https=) |
| WO (1) | WO2016124926A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| JP5965409B2 (ja) | 2010-12-08 | 2016-08-03 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 創傷滲出液を評価するための統合システム |
| PL2648795T3 (pl) | 2010-12-08 | 2023-05-08 | Convatec Technologies Inc. | System do usuwania wysięków z miejsca rany |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| JP2016507663A (ja) | 2012-12-20 | 2016-03-10 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 化学修飾セルロース系繊維の加工 |
| AU2014393037B2 (en) | 2014-04-30 | 2019-02-28 | Matoke Holdings Limited | Antimicrobial compositions |
| JP6738833B2 (ja) | 2015-04-28 | 2020-08-12 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 抗細菌性ナノファイバー |
| AU2016296150A1 (en) * | 2015-07-23 | 2018-03-01 | Matoke Holdings Limited | Antimicrobial compositions and formulations releasing hydrogen peroxide |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| WO2017212345A2 (en) | 2016-03-30 | 2017-12-14 | Synovo Gmbh | Detecting microbial infection in wounds |
| WO2017173069A1 (en) | 2016-03-30 | 2017-10-05 | Convatec Technologies Inc. | Detecting microbial infections in wounds |
| US20200323963A1 (en) * | 2016-04-12 | 2020-10-15 | Matoke Holdings Limited | Antimicrobial fibers and compositions |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| JP7071957B2 (ja) | 2016-07-08 | 2022-05-19 | コンバテック・テクノロジーズ・インコーポレイテッド | 可撓性陰圧システム |
| BR112019000284A2 (pt) | 2016-07-08 | 2019-04-16 | Convatec Technologies Inc. | aparelho de coleta de fluido |
| ES2912094T3 (es) | 2016-07-08 | 2022-05-24 | Convatec Technologies Inc | Detección de flujo de fluidos |
| WO2018065789A1 (en) | 2016-10-06 | 2018-04-12 | Matoke Holdings Limited | Antimicrobial compositions |
| EP3522717B1 (en) | 2016-10-06 | 2024-01-24 | Matoke Holdings Limited | Antimicrobial compositions |
| CA3046574C (en) * | 2016-12-12 | 2023-08-01 | John Ha-Thanh LUONG | Antibacterial products and processes for preparing antibacterial products from maple syrup |
| GB201716986D0 (en) | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| US12161792B2 (en) | 2017-11-16 | 2024-12-10 | Convatec Limited | Fluid collection apparatus |
| GB201805996D0 (en) * | 2018-04-11 | 2018-05-23 | Matoke Holdings Ltd | Tissue scaffold |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| EP3946481B1 (en) | 2019-03-27 | 2026-03-04 | Matoke Holdings Limited | Antimicrobial compositions |
| EP4295869B1 (en) | 2019-06-03 | 2026-01-28 | Convatec Limited | Devices to disrupt and contain pathogens |
| CN110353883A (zh) * | 2019-07-10 | 2019-10-22 | 重庆市人民医院 | 用于治疗褥疮的复合敷料层及带有复合敷料层的褥疮贴 |
| CN110496525A (zh) * | 2019-08-30 | 2019-11-26 | 山东多芬农业有限公司 | 空气净化剂及其制备和使用方法 |
| IL270762B (en) * | 2019-11-19 | 2021-10-31 | Sion Biotext Medical Ltd | Wound dressing comprising a combination of hydrogel and honey, method of preparation and uses thereof |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| WO2021186165A1 (en) | 2020-03-16 | 2021-09-23 | Matoke Holdings Limited | Antimicrobial compositions |
| GB202106320D0 (en) | 2021-05-04 | 2021-06-16 | Matoke Holdings Ltd | Antimicrobial dressing |
| CN114732799B (zh) * | 2022-03-29 | 2023-09-22 | 南京大学 | 一种自供电的无载药抗菌贴片 |
| GB202210839D0 (en) | 2022-07-25 | 2022-09-07 | Matoke Holdings Ltd | Antimicrobial compositions |
| GB202309435D0 (en) | 2023-06-22 | 2023-08-09 | Matoke Holdings Ltd | Antimicrobial device |
| WO2025012618A1 (en) | 2023-07-07 | 2025-01-16 | Matoke Holdings Limited | Antimicrobial compositions |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1987893A (en) | 1931-03-26 | 1935-01-15 | Cornell Universlty | Honey process and product |
| US4576817A (en) * | 1984-06-07 | 1986-03-18 | Laclede Professional Products, Inc. | Enzymatic bandages and pads |
| EP0236610A1 (en) * | 1986-03-13 | 1987-09-16 | Laclede Professional Products, Inc. | Enzymatic bandages and pads |
| WO1992011042A1 (en) * | 1990-12-19 | 1992-07-09 | Allergan, Inc. | Compositions and methods for contact lens disinfecting |
| TR200001273T2 (tr) * | 1997-11-05 | 2000-11-21 | Koppert B.V. | Patojenik bitki mikroorganizmalarına karşı öldürücü ilaç |
| US6214339B1 (en) * | 2000-01-12 | 2001-04-10 | Michael A. Pellico | Di-enzymatic treatment of outer ear infection in dogs and cats |
| GB2382527A (en) * | 2001-12-03 | 2003-06-04 | Acordis Speciality Fibres Ltd | Wound dressings |
| PT1693073E (pt) * | 2002-04-24 | 2014-09-18 | Archimed Llp | Pensos para feridas incluindo hidrogéis hidratados e enzimas |
| US20060142684A1 (en) * | 2003-04-11 | 2006-06-29 | Shanbrom Technologies, Llc | Oxygen releasing material |
| MX2007000918A (es) * | 2004-07-22 | 2007-12-04 | Hemo Nanoscience Llc | Composiciones y metodos para tratar sangrado excesivo. |
| BE1017155A3 (nl) * | 2006-06-01 | 2008-03-04 | Sanomedical Bvba | Wondverzorgingsproduct. |
| GB0619786D0 (en) * | 2006-10-06 | 2006-11-15 | Inst Of Technology Sligo | An antimicrobial and immunostimulatory system |
| WO2008045696A2 (en) * | 2006-10-10 | 2008-04-17 | Laclede, Inc. | Methods and compositions for the treatment of vaginal diseases employing peroxide-producing enzymes and peroxidases |
| WO2008049251A1 (de) | 2006-10-23 | 2008-05-02 | Schoeller Textil Ag | Mikrobizide nano- und mesopolymerfasern aus polymeren und honig für textile anwendungen |
| BE1017344A3 (nl) | 2006-10-27 | 2008-06-03 | Cnci Bvba | Methode voor het steriliseren van ruwe, onverhitte honing, preparaat voor wondverzorging op basis van honing en een wondverzorging behandelingsproduct. |
| US8512731B2 (en) * | 2007-11-13 | 2013-08-20 | Medtronic Minimed, Inc. | Antimicrobial coatings for medical devices and methods for making and using them |
| US20110111012A1 (en) | 2009-11-12 | 2011-05-12 | Hemcon Medical Technologies, Inc. | Nanomaterial wound dressing assembly |
| US20130273020A1 (en) * | 2010-08-30 | 2013-10-17 | Comvita New Zealand Limited | Antifungal composition |
| EP2510944A1 (en) * | 2011-04-15 | 2012-10-17 | National University of Ireland, Galway | Treatment of bacterial infections |
| EP2851085B1 (en) * | 2012-05-14 | 2019-06-26 | Teijin Limited | Protein ccomposition sterilized by radiation |
| US20150030688A1 (en) * | 2013-07-25 | 2015-01-29 | Saint Louis University | Honey and growth factor eluting scaffold for wound healing and tissue engineering |
| AU2014393037B2 (en) * | 2014-04-30 | 2019-02-28 | Matoke Holdings Limited | Antimicrobial compositions |
| AU2015301070B2 (en) * | 2014-08-05 | 2021-01-28 | The University Of Memphis | Compositions and methods for enhancing healing and regeneration of bone and soft tissue |
| BR112017010808A2 (pt) * | 2014-11-24 | 2017-12-26 | Matoke Holdings Ltd | prevenção e tratamento de infecções microbianas |
-
2016
- 2016-02-03 EP EP16711333.1A patent/EP3253424B1/en active Active
- 2016-02-03 AU AU2016214119A patent/AU2016214119B2/en active Active
- 2016-02-03 GB GB1908998.6A patent/GB2573068B/en active Active
- 2016-02-03 CA CA2975197A patent/CA2975197A1/en not_active Abandoned
- 2016-02-03 CN CN201680020338.0A patent/CN107708752A/zh active Pending
- 2016-02-03 GB GB1711217.8A patent/GB2550301B/en active Active
- 2016-02-03 US US15/547,972 patent/US20180023217A1/en active Pending
- 2016-02-03 BR BR112017016545A patent/BR112017016545A2/pt active Search and Examination
- 2016-02-03 EP EP20212485.5A patent/EP3858392B1/en active Active
- 2016-02-03 WO PCT/GB2016/050253 patent/WO2016124926A1/en not_active Ceased
- 2016-02-03 JP JP2017540823A patent/JP2018507033A/ja active Pending
- 2016-02-03 HK HK18106171.8A patent/HK1246699A1/zh unknown
-
2019
- 2019-02-15 JP JP2019025152A patent/JP2019080985A/ja active Pending
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