JP2018506995A5 - - Google Patents
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- Publication number
- JP2018506995A5 JP2018506995A5 JP2017562971A JP2017562971A JP2018506995A5 JP 2018506995 A5 JP2018506995 A5 JP 2018506995A5 JP 2017562971 A JP2017562971 A JP 2017562971A JP 2017562971 A JP2017562971 A JP 2017562971A JP 2018506995 A5 JP2018506995 A5 JP 2018506995A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- transgene
- cell
- sequence encoding
- dhfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120329P | 2015-02-24 | 2015-02-24 | |
| US62/120,329 | 2015-02-24 | ||
| US201562120790P | 2015-02-25 | 2015-02-25 | |
| US62/120,790 | 2015-02-25 | ||
| US201562175794P | 2015-06-15 | 2015-06-15 | |
| US62/175,794 | 2015-06-15 | ||
| PCT/US2016/019288 WO2016138091A2 (en) | 2015-02-24 | 2016-02-24 | Selection methods for genetically-modified t cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018506995A JP2018506995A (ja) | 2018-03-15 |
| JP2018506995A5 true JP2018506995A5 (enExample) | 2019-03-14 |
| JP6947647B2 JP6947647B2 (ja) | 2021-10-13 |
Family
ID=56464271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017562971A Active JP6947647B2 (ja) | 2015-02-24 | 2016-02-24 | 遺伝子改変ｔ細胞の選択方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10808230B2 (enExample) |
| EP (2) | EP3804741A3 (enExample) |
| JP (1) | JP6947647B2 (enExample) |
| KR (1) | KR20170117095A (enExample) |
| CN (1) | CN107667169B (enExample) |
| AU (2) | AU2016222850B2 (enExample) |
| CA (1) | CA2976126A1 (enExample) |
| WO (1) | WO2016138091A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3974520A1 (en) | 2013-05-14 | 2022-03-30 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| CA3190002A1 (en) | 2014-02-14 | 2015-08-20 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| WO2016073629A1 (en) | 2014-11-05 | 2016-05-12 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| CA2977818A1 (en) | 2015-03-11 | 2016-09-15 | Board Of Regents, The University Of Texas System | Transposase polypeptides and uses thereof |
| KR20180042449A (ko) | 2015-09-15 | 2018-04-25 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | T 세포 수용체(tcr) 결합 항체 및 이의 용도 |
| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| CA3064000A1 (en) | 2017-05-24 | 2018-11-29 | Effector Therapeutics, Inc. | Methods and compositions for cellular immunotherapy |
| CN109136282A (zh) * | 2018-09-30 | 2019-01-04 | 北京鼎成肽源生物技术有限公司 | 一种hafft1细胞的构建方法 |
| WO2020102726A1 (en) * | 2018-11-16 | 2020-05-22 | Rapa Therapeutics, Llc | Method for manufacturing of human hybrid regulatory t/th2 cells (hybrid treg/th2 cells) from de-differentiated t cells |
| CN113573778B (zh) | 2018-11-16 | 2025-05-13 | 拉帕治疗有限公司 | 使用诱导性调节性T（iTREG）细胞进行的ALS治疗 |
| KR102594009B1 (ko) | 2021-02-01 | 2023-10-24 | 서울대학교산학협력단 | 형질전환 생식세포의 제조 방법 및 이를 이용한 형질전환 동물의 제조 방법 |
| JP2024533772A (ja) * | 2021-09-30 | 2024-09-12 | ユニバーシティ オブ サザン カリフォルニア | ヒト肝細胞培養培地およびｉｎ ｖｉｔｒｏ培養ヒト肝細胞の馴化培地ならびにその使用 |
| CN114740196B (zh) * | 2022-04-08 | 2023-04-18 | 中南大学湘雅二医院 | 标志物及其在制备评价机体免疫功能的产品中的应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101361416B1 (ko) * | 2008-10-08 | 2014-02-21 | 인트렉손 코포레이션 | 다수의 면역조절자를 발현하는 조작된 세포 및 그 용도 |
| ES2743507T3 (es) * | 2009-11-02 | 2020-02-19 | Univ Emory | Inmunoterapia resistente a fármaco para el tratamiento de un cáncer |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US8809017B2 (en) * | 2011-05-24 | 2014-08-19 | Agency For Science, Technology And Research | IRES mediated multicistronic vectors |
| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| EP3594245A1 (en) * | 2012-02-13 | 2020-01-15 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| EP3974520A1 (en) | 2013-05-14 | 2022-03-30 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| WO2014190273A1 (en) | 2013-05-24 | 2014-11-27 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| CN105848484A (zh) | 2013-10-25 | 2016-08-10 | 得克萨斯州大学系统董事会 | 用于免疫治疗的多克隆γδ T细胞 |
| EP3071687B1 (en) * | 2013-11-22 | 2019-07-31 | Cellectis | Method of engineering chemotherapy drug resistant t-cells for immunotherapy |
| CA3190002A1 (en) | 2014-02-14 | 2015-08-20 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| AU2015243849B2 (en) * | 2014-04-10 | 2020-12-17 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Transgene genetic tags and methods of use |
| US20170158749A1 (en) | 2014-04-23 | 2017-06-08 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) and methods for making and using the same |
| WO2015164740A1 (en) | 2014-04-24 | 2015-10-29 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| WO2016073629A1 (en) | 2014-11-05 | 2016-05-12 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| KR20170075785A (ko) | 2014-11-05 | 2017-07-03 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 유전자 변형된 면역 효과기 세포 및 면역 효과기 세포의 증식용 가공된 세포 |
| CA2977818A1 (en) | 2015-03-11 | 2016-09-15 | Board Of Regents, The University Of Texas System | Transposase polypeptides and uses thereof |
| KR20180042449A (ko) | 2015-09-15 | 2018-04-25 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | T 세포 수용체(tcr) 결합 항체 및 이의 용도 |
| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
-
2016
- 2016-02-24 EP EP20191615.2A patent/EP3804741A3/en not_active Withdrawn
- 2016-02-24 AU AU2016222850A patent/AU2016222850B2/en not_active Ceased
- 2016-02-24 CA CA2976126A patent/CA2976126A1/en active Pending
- 2016-02-24 KR KR1020177024195A patent/KR20170117095A/ko not_active Withdrawn
- 2016-02-24 WO PCT/US2016/019288 patent/WO2016138091A2/en not_active Ceased
- 2016-02-24 EP EP16741163.6A patent/EP3261656B1/en active Active
- 2016-02-24 JP JP2017562971A patent/JP6947647B2/ja active Active
- 2016-02-24 CN CN201680011714.XA patent/CN107667169B/zh not_active Expired - Fee Related
- 2016-02-24 US US15/552,821 patent/US10808230B2/en active Active
-
2020
- 2020-09-04 US US17/013,195 patent/US20210054346A1/en not_active Abandoned
-
2021
- 2021-06-02 AU AU2021203606A patent/AU2021203606A1/en not_active Abandoned
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