JP2018505901A5 - - Google Patents
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- Publication number
- JP2018505901A5 JP2018505901A5 JP2017543816A JP2017543816A JP2018505901A5 JP 2018505901 A5 JP2018505901 A5 JP 2018505901A5 JP 2017543816 A JP2017543816 A JP 2017543816A JP 2017543816 A JP2017543816 A JP 2017543816A JP 2018505901 A5 JP2018505901 A5 JP 2018505901A5
- Authority
- JP
- Japan
- Prior art keywords
- daily dose
- day
- schizophrenia
- iloperidone
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XMXHEBAFVSFQEX-UHFFFAOYSA-N iloperidone Chemical compound COC1=CC(C(C)=O)=CC=C1OCCCN1CCC(C=2C3=CC=C(F)C=C3ON=2)CC1 XMXHEBAFVSFQEX-UHFFFAOYSA-N 0.000 claims description 20
- 201000000980 schizophrenia Diseases 0.000 claims description 17
- 229960003162 iloperidone Drugs 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 9
- 230000001154 acute effect Effects 0.000 claims description 7
- 238000011282 treatment Methods 0.000 claims description 7
- 208000024891 symptom Diseases 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 2
- 238000011418 maintenance treatment Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 10
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 238000000034 method Methods 0.000 description 17
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562117173P | 2015-02-17 | 2015-02-17 | |
| US62/117,173 | 2015-02-17 | ||
| US201562172436P | 2015-06-08 | 2015-06-08 | |
| US62/172,436 | 2015-06-08 | ||
| PCT/US2016/018316 WO2016134049A1 (en) | 2015-02-17 | 2016-02-17 | Iloperidone for the treatment of schizophrenia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505901A JP2018505901A (ja) | 2018-03-01 |
| JP2018505901A5 true JP2018505901A5 (enExample) | 2019-03-28 |
| JP6885649B2 JP6885649B2 (ja) | 2021-06-16 |
Family
ID=55532275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017543816A Active JP6885649B2 (ja) | 2015-02-17 | 2016-02-17 | 統合失調症の治療のためのイロペリドン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10441580B2 (enExample) |
| EP (1) | EP3258935B1 (enExample) |
| JP (1) | JP6885649B2 (enExample) |
| KR (1) | KR102870956B1 (enExample) |
| CN (2) | CN116211857A (enExample) |
| BR (1) | BR112017017608A2 (enExample) |
| CA (1) | CA2976383C (enExample) |
| ES (1) | ES2870498T3 (enExample) |
| WO (1) | WO2016134049A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11214827B2 (en) * | 2018-08-30 | 2022-01-04 | Vanda Pharmaceuticals Inc. | Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone |
| WO2024137439A1 (en) * | 2022-12-19 | 2024-06-27 | Vanda Pharmaceuticals Inc. | Dosage regime of iloperidone for treating bipolar i disorder and schizophrenia |
| CN121218989A (zh) | 2023-06-02 | 2025-12-26 | 万达制药公司 | 使用伊潘立酮的治疗方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050020632A1 (en) | 2001-08-31 | 2005-01-27 | Dominique Grimler | Optical isomers of an iloperidone metabolite |
| JP5067998B2 (ja) | 2001-10-30 | 2012-11-07 | ノバルティス アーゲー | イロペリドンおよび星形ポリマーのデポー製剤 |
| GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
| US20100063093A1 (en) * | 2007-03-28 | 2010-03-11 | Curt Wolfgang | Methods for the administration of iloperidone |
| ES2825949T3 (es) | 2004-09-30 | 2021-05-17 | Vanda Pharmaceuticals Inc | Métodos para administrar iloperidona |
| EP2198049A1 (en) * | 2007-09-10 | 2010-06-23 | Vanda Pharmaceuticals Inc. | Antipsychotic treatment based on snp genotype |
| SI2234617T2 (sl) | 2007-12-19 | 2025-05-30 | Janssen Pharmaceutica Nv | Režim odmerjanja v zvezi z dolgodelujočimi paliperidonijevimi estri za injiciranje |
| EP2430183B1 (en) * | 2009-05-15 | 2014-12-17 | Vanda Pharmaceuticals Inc. | Antipsychotic treatment based on drd2 or ankk1 snp genotype |
| CN104220074A (zh) | 2011-12-02 | 2014-12-17 | 大日本住友制药株式会社 | 鲁拉西酮新给药方案以及其用于治疗、预防和/或控制至少一种cns病症的用途 |
| CN108938632A (zh) | 2012-03-14 | 2018-12-07 | 万达制药公司 | 用于治疗精神疾病的伊潘立酮代谢物及其应用 |
| KR102121633B1 (ko) * | 2012-08-21 | 2020-06-10 | 세이지 테라퓨틱스, 인크. | 간질 또는 간질지속 상태를 치료하는 방법 |
-
2016
- 2016-02-17 BR BR112017017608-4A patent/BR112017017608A2/en not_active Application Discontinuation
- 2016-02-17 WO PCT/US2016/018316 patent/WO2016134049A1/en not_active Ceased
- 2016-02-17 ES ES16710038T patent/ES2870498T3/es active Active
- 2016-02-17 EP EP16710038.7A patent/EP3258935B1/en active Active
- 2016-02-17 CN CN202310398029.9A patent/CN116211857A/zh active Pending
- 2016-02-17 CA CA2976383A patent/CA2976383C/en active Active
- 2016-02-17 KR KR1020177026225A patent/KR102870956B1/ko active Active
- 2016-02-17 CN CN201680010479.4A patent/CN107249586A/zh active Pending
- 2016-02-17 JP JP2017543816A patent/JP6885649B2/ja active Active
- 2016-02-17 US US15/549,820 patent/US10441580B2/en active Active
-
2019
- 2019-09-06 US US16/562,548 patent/US10987346B2/en active Active
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