ES2870498T3 - Iloperidona para el tratamiento de esquizofrenia - Google Patents

Iloperidona para el tratamiento de esquizofrenia Download PDF

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Publication number
ES2870498T3
ES2870498T3 ES16710038T ES16710038T ES2870498T3 ES 2870498 T3 ES2870498 T3 ES 2870498T3 ES 16710038 T ES16710038 T ES 16710038T ES 16710038 T ES16710038 T ES 16710038T ES 2870498 T3 ES2870498 T3 ES 2870498T3
Authority
ES
Spain
Prior art keywords
iloperidone
dose
daily
patients
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16710038T
Other languages
English (en)
Spanish (es)
Inventor
Mihael H Polymeropoulos
Curt D Wolfgang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanda Pharmaceuticals Inc
Original Assignee
Vanda Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanda Pharmaceuticals Inc filed Critical Vanda Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2870498T3 publication Critical patent/ES2870498T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES16710038T 2015-02-17 2016-02-17 Iloperidona para el tratamiento de esquizofrenia Active ES2870498T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562117173P 2015-02-17 2015-02-17
US201562172436P 2015-06-08 2015-06-08
PCT/US2016/018316 WO2016134049A1 (en) 2015-02-17 2016-02-17 Iloperidone for the treatment of schizophrenia

Publications (1)

Publication Number Publication Date
ES2870498T3 true ES2870498T3 (es) 2021-10-27

Family

ID=55532275

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16710038T Active ES2870498T3 (es) 2015-02-17 2016-02-17 Iloperidona para el tratamiento de esquizofrenia

Country Status (9)

Country Link
US (2) US10441580B2 (enExample)
EP (1) EP3258935B1 (enExample)
JP (1) JP6885649B2 (enExample)
KR (1) KR102870956B1 (enExample)
CN (2) CN116211857A (enExample)
BR (1) BR112017017608A2 (enExample)
CA (1) CA2976383C (enExample)
ES (1) ES2870498T3 (enExample)
WO (1) WO2016134049A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11214827B2 (en) 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
IL321015A (en) * 2022-12-19 2025-07-01 Vanda Pharmaceuticals Inc ILOPERIDONE dosing regimen for the treatment of bipolar I disorder and schizophrenia
AU2024278999A1 (en) 2023-06-02 2025-11-13 Vanda Pharmaceuticals Inc. Method of treatment with iloperidone

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2370634T3 (es) 2001-08-31 2011-12-21 Novartis Ag Isómeros ópticos de un metabolito de iloperidona.
WO2003037337A1 (en) 2001-10-30 2003-05-08 Novartis Ag Depot formulations of iloperidone and a star polymer
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
US20100063093A1 (en) * 2007-03-28 2010-03-11 Curt Wolfgang Methods for the administration of iloperidone
CA3113166A1 (en) * 2004-09-30 2006-04-13 Vanda Pharmaceuticals Inc. Methods for the administration of iloperidone
WO2009036056A1 (en) 2007-09-10 2009-03-19 Vanda Pharmaceuticals, Inc. Antipsychotic treatment based on snp genotype
HUE053904T2 (hu) 2007-12-19 2021-07-28 Janssen Pharmaceutica Nv Hosszan tartó hatású injektálható paliperidon-észterekkel kapcsolatos adagolási rendek
ES2533091T3 (es) * 2009-05-15 2015-04-07 Vanda Pharmaceuticals Inc. Tratamiento antipsicótico basado en genotipo de SNP de DRD2 o ANKK1
US20140350029A1 (en) 2011-12-02 2014-11-27 Dainippon Sumitomo Pharma Co., Ltd. Lurasidone novel dosage regimens and use thereof for the treatment, prevention, and/or management of at least one cns disorder
CN108938632A (zh) 2012-03-14 2018-12-07 万达制药公司 用于治疗精神疾病的伊潘立酮代谢物及其应用
IL275725B (en) * 2012-08-21 2022-08-01 Sage Therapeutics Inc Treatment methods for epilepsy and status epilepticus

Also Published As

Publication number Publication date
US10987346B2 (en) 2021-04-27
EP3258935B1 (en) 2021-04-07
CA2976383C (en) 2023-05-23
EP3258935A1 (en) 2017-12-27
US10441580B2 (en) 2019-10-15
HK1248551A1 (zh) 2018-10-19
CN116211857A (zh) 2023-06-06
KR20170118830A (ko) 2017-10-25
BR112017017608A2 (en) 2018-05-08
JP6885649B2 (ja) 2021-06-16
JP2018505901A (ja) 2018-03-01
CA2976383A1 (en) 2016-08-25
KR102870956B1 (ko) 2025-10-16
US20190388412A1 (en) 2019-12-26
WO2016134049A1 (en) 2016-08-25
US20180021324A1 (en) 2018-01-25
CN107249586A (zh) 2017-10-13

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UA95167U (uk) Спосіб лікування невропатії лицевого нерва у дітей з використанням препаратів метаболічної дії