JP2018505862A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018505862A5 JP2018505862A5 JP2017533337A JP2017533337A JP2018505862A5 JP 2018505862 A5 JP2018505862 A5 JP 2018505862A5 JP 2017533337 A JP2017533337 A JP 2017533337A JP 2017533337 A JP2017533337 A JP 2017533337A JP 2018505862 A5 JP2018505862 A5 JP 2018505862A5
- Authority
- JP
- Japan
- Prior art keywords
- powder
- liquid composition
- phosphate
- amount
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000843 powder Substances 0.000 claims 29
- 239000000203 mixture Substances 0.000 claims 10
- 239000007788 liquid Substances 0.000 claims 8
- 230000001684 chronic effect Effects 0.000 claims 3
- 230000028327 secretion Effects 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 239000001736 Calcium glycerylphosphate Substances 0.000 claims 2
- 206010031009 Oral pain Diseases 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 208000005946 Xerostomia Diseases 0.000 claims 2
- UHHRFSOMMCWGSO-UHFFFAOYSA-L calcium glycerophosphate Chemical compound [Ca+2].OCC(CO)OP([O-])([O-])=O UHHRFSOMMCWGSO-UHFFFAOYSA-L 0.000 claims 2
- 229940095618 calcium glycerophosphate Drugs 0.000 claims 2
- 235000019299 calcium glycerylphosphate Nutrition 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 206010013781 dry mouth Diseases 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims 2
- 235000019799 monosodium phosphate Nutrition 0.000 claims 2
- 210000000214 mouth Anatomy 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 208000003265 stomatitis Diseases 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 229940125715 antihistaminic agent Drugs 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229960005069 calcium Drugs 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229910001424 calcium ion Inorganic materials 0.000 claims 1
- 229940041131 calcium lactate gluconate Drugs 0.000 claims 1
- PWKNEBQRTUXXLT-ZBHRUSISSA-L calcium lactate gluconate Chemical compound [Ca+2].CC(O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O PWKNEBQRTUXXLT-ZBHRUSISSA-L 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229960001334 corticosteroids Drugs 0.000 claims 1
- 238000007599 discharging Methods 0.000 claims 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims 1
- 150000004673 fluoride salts Chemical class 0.000 claims 1
- 239000006174 pH buffer Substances 0.000 claims 1
- 239000006179 pH buffering agent Substances 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 235000011008 sodium phosphates Nutrition 0.000 claims 1
- DFIWJEVKLWMZBI-UHFFFAOYSA-M sodium;dihydrogen phosphate;phosphoric acid Chemical compound [Na+].OP(O)(O)=O.OP(O)([O-])=O DFIWJEVKLWMZBI-UHFFFAOYSA-M 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
- 239000012905 visible particle Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462093026P | 2014-12-17 | 2014-12-17 | |
| US62/093,026 | 2014-12-17 | ||
| PCT/CA2015/051327 WO2016095036A1 (en) | 2014-12-17 | 2015-12-15 | Formulations of calcium and phosphate for oral inflammation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505862A JP2018505862A (ja) | 2018-03-01 |
| JP2018505862A5 true JP2018505862A5 (enExample) | 2019-01-31 |
| JP6781701B2 JP6781701B2 (ja) | 2020-11-04 |
Family
ID=56125518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533337A Active JP6781701B2 (ja) | 2014-12-17 | 2015-12-15 | 口内炎用のカルシウムおよびリン酸塩の製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11590165B2 (enExample) |
| EP (1) | EP3233092B1 (enExample) |
| JP (1) | JP6781701B2 (enExample) |
| KR (1) | KR102397070B1 (enExample) |
| CN (1) | CN107530374B (enExample) |
| AU (1) | AU2015367208B2 (enExample) |
| BR (1) | BR112017013158B1 (enExample) |
| CA (1) | CA2971224C (enExample) |
| MX (1) | MX372952B (enExample) |
| WO (1) | WO2016095036A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10765650B2 (en) * | 2016-02-03 | 2020-09-08 | Forward Science Technologies, LLC | Artificial saliva |
| US10143635B2 (en) * | 2016-02-03 | 2018-12-04 | Forward Science Technologies, LLC | Artificial saliva |
| GR1009399B (el) * | 2017-06-23 | 2018-11-15 | Χρηστος Γεωργιου Φυτας | Στοματικο διαλυμα κατα της ξηροστομιας και στοματοφαρυγγικης βλεννογονιτιδας |
| WO2023183556A2 (en) * | 2022-03-24 | 2023-09-28 | Amcyte Pharma, Inc. | Treatment for retinal disorders |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB572352A (en) * | 1944-02-26 | 1945-10-03 | Charles Somerville Dillon | Improved tooth powder or preparation |
| US4716035A (en) | 1985-05-24 | 1987-12-29 | The Procter & Gamble Company | Oral compositions and methods for treating gingivitis |
| US5540913A (en) | 1987-03-17 | 1996-07-30 | Turner; Robert E. | Formulations and uses thereof in the prevention and treatment of oral lesions |
| US5268267A (en) | 1987-08-21 | 1993-12-07 | The General Hospital Corporation | Method for diagnosing small cell carcinoma |
| US5427768A (en) | 1993-06-23 | 1995-06-27 | American Dental Association Health Foundation | Carbonated solutions for treating, mineralizing and fluoridating calcified tissues and methods for their use |
| AU695356B2 (en) * | 1995-02-24 | 1998-08-13 | American Dental Association Health Foundation | Carbonated solutions for treating, mineralizing and fluoridating calcified tissues and methods for their use |
| MX9801063A (es) | 1995-08-08 | 1998-05-31 | Enamelon Inc | Productos y metodos mejorados para la remineralizacion de lesiones en dientes. |
| US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
| US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| PT939613E (pt) * | 1996-09-18 | 2003-07-31 | Erling Johansen | Solucao sobressaturada para lavagem bucal contendo ioes calcio e fosfato |
| US6159448A (en) * | 1996-09-27 | 2000-12-12 | Enamelon, Inc. | Products and methods for the remineralization and prevention of demineralization of teeth |
| US7838046B2 (en) * | 2001-09-26 | 2010-11-23 | Tampa Bay Research Institute | Plant extracts and uses thereof |
| CA2517005A1 (en) * | 2003-02-20 | 2004-09-02 | Santarus, Inc. | A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
| JP4669960B2 (ja) | 2003-06-03 | 2011-04-13 | 株式会社 メドレックス | 局所麻酔薬を含有する口中用または咽頭部用製剤 |
| US20070185194A1 (en) * | 2003-07-01 | 2007-08-09 | Kamal Mehta | Stable oral compositions of azithromycin monohydrate |
| AR045068A1 (es) * | 2003-07-23 | 2005-10-12 | Univ Missouri | Formulacion de liberacion inmediata de composiciones farmaceuticas |
| EP1718303A4 (en) * | 2004-02-10 | 2010-09-01 | Santarus Inc | COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG |
| US8518383B2 (en) | 2006-02-03 | 2013-08-27 | Wm. Wrigley Jr. Company | Oral care products comprising buffer systems for improved mineralization/remineralization benefits |
| MX2008012524A (es) * | 2006-04-05 | 2008-10-10 | Cadbury Adams Usa Llc | Complejo de fosfato de calcio y sales en sistemas de liberacion oral. |
| TWI445540B (zh) * | 2007-04-20 | 2014-07-21 | Ajinomoto Kk | 抗低體溫組成物 |
| JP5166780B2 (ja) * | 2007-06-20 | 2013-03-21 | 花王株式会社 | 液体口腔用組成物 |
| US20090023771A1 (en) * | 2007-07-18 | 2009-01-22 | The Curators Of The University Of Missouri | Pharmaceutical composition comprising a proton pump inhibitor and protein component |
| US9358242B2 (en) * | 2007-08-30 | 2016-06-07 | Prelief Inc. | Calcium glycerophosphate for treating and preventing respiratory diseases or conditions |
| US20090130232A1 (en) | 2007-11-20 | 2009-05-21 | Mohammed Zahra | Composition and method for treatment of oral inflammation an ulceration |
| US20090239957A1 (en) * | 2007-12-21 | 2009-09-24 | Alcon Research, Ltd. | Stabilized glycerophosphate-containing surgical irrigating solution |
| CN101980700A (zh) * | 2008-02-20 | 2011-02-23 | 密苏里大学董事会 | 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法 |
| JP2009235012A (ja) | 2008-03-28 | 2009-10-15 | Gc Corp | 口腔湿潤用組成物 |
| EP2349189B1 (en) | 2008-11-14 | 2015-08-05 | Swissdent Cosmetics AG | Biomimetic oral care composition |
| CN101584889B (zh) | 2009-07-10 | 2012-12-12 | 山东大学威海分校 | 一种用于治疗牙周病的外用原位成型基质 |
| US20110086108A1 (en) | 2009-10-12 | 2011-04-14 | Bartholomew Weldon | Dissolving powders that can be mixed with water and used as an oral rinse |
| JP5485677B2 (ja) | 2009-12-16 | 2014-05-07 | 花王株式会社 | 口腔用組成物 |
| KR102120160B1 (ko) * | 2010-08-07 | 2020-06-08 | 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 | 구강용 조성물 |
| US11090259B2 (en) * | 2012-11-16 | 2021-08-17 | Eusa Pharma (Uk) Ltd | Effervescent tablet |
-
2015
- 2015-11-19 US US14/945,865 patent/US11590165B2/en active Active
- 2015-12-15 AU AU2015367208A patent/AU2015367208B2/en active Active
- 2015-12-15 JP JP2017533337A patent/JP6781701B2/ja active Active
- 2015-12-15 KR KR1020177019831A patent/KR102397070B1/ko active Active
- 2015-12-15 WO PCT/CA2015/051327 patent/WO2016095036A1/en not_active Ceased
- 2015-12-15 CA CA2971224A patent/CA2971224C/en active Active
- 2015-12-15 CN CN201580075768.8A patent/CN107530374B/zh active Active
- 2015-12-15 BR BR112017013158-7A patent/BR112017013158B1/pt active IP Right Grant
- 2015-12-15 MX MX2017007741A patent/MX372952B/es active IP Right Grant
- 2015-12-15 EP EP15868778.0A patent/EP3233092B1/en active Active
-
2023
- 2023-02-24 US US18/113,939 patent/US20230241102A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018505862A5 (enExample) | ||
| RU2013133680A (ru) | Композиции солей металла | |
| RU2015126801A (ru) | Фторид-стабильные цинкосодержащие композиции для ухода за полостью рта | |
| JP2011511795A5 (enExample) | ||
| JP2011511793A5 (enExample) | ||
| RU2016150160A (ru) | Композиции для ухода за полостью рта, содержащие ионы металлов | |
| JP2011511067A5 (enExample) | ||
| RU2015126796A (ru) | Композиции, содержащие фосфат цинка | |
| JP2014208658A5 (enExample) | ||
| RU2013130973A (ru) | Композиции средств для чистки зубов, содержащие силикат кальция и основную аминокислоту | |
| RU2015123751A (ru) | Ополаскиватель для полости рта с галогенидом цинка-аминокислоты | |
| RU2013156999A (ru) | Композиции для ухода за полостью рта, содержащие фитиновую кислоту | |
| JP2014223081A5 (enExample) | ||
| JP2017002035A5 (enExample) | ||
| Souza et al. | Effect of experimental mouthrinses containing the combination of NaF and TiF4 on enamel erosive wear in vitro | |
| RU2010137342A (ru) | Композиции и способы лечения ксеростомии | |
| RU2017101869A (ru) | Способ получения покрытых цитратом и легированных фторидом наночастиц аморфного фосфата кальция | |
| RU2016148009A (ru) | Композиция для предотвращения или лечения эрозии зубов | |
| WO2015172354A1 (en) | Dentifrice compositions having improved fluoride ion stability or fluoride uptake | |
| WO2012135426A3 (en) | Anti-bacterial and mineralizing calcium phosphate compositions | |
| JP2008533183A5 (enExample) | ||
| RU2015120334A (ru) | Отбеливатели зубов | |
| MX372952B (es) | Formulaciones de calcio y fosfato para inflamacion oral. | |
| MX365972B (es) | Composiciones para el cuidado bucal. | |
| JP6659465B2 (ja) | 口腔用組成物 |