JP2018500351A5 - - Google Patents
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- Publication number
- JP2018500351A5 JP2018500351A5 JP2017533901A JP2017533901A JP2018500351A5 JP 2018500351 A5 JP2018500351 A5 JP 2018500351A5 JP 2017533901 A JP2017533901 A JP 2017533901A JP 2017533901 A JP2017533901 A JP 2017533901A JP 2018500351 A5 JP2018500351 A5 JP 2018500351A5
- Authority
- JP
- Japan
- Prior art keywords
- trans
- phenyl
- amino
- cyclohexyl
- phenylpyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- TZDFCQQFICPDHL-UHFFFAOYSA-N CCC(C(C)C1CCC(CC(Nc2nnc(-c3ccc(C(C4)(CC4=[F])N)cc3)c(-c3ccccc3)c2)=O)CC1)=O Chemical compound CCC(C(C)C1CCC(CC(Nc2nnc(-c3ccc(C(C4)(CC4=[F])N)cc3)c(-c3ccccc3)c2)=O)CC1)=O TZDFCQQFICPDHL-UHFFFAOYSA-N 0.000 description 1
- FDFNITYLYNNGMR-VCCPSZSWSA-N CCC(CC(CC)=O)[C@H]1CC[C@H](CC(Nc2ncc(-c3ccc([C@](C4)(C[C@@]4(C)O)N)cc3)c(-c3ccccc3)c2)=O)CC1 Chemical compound CCC(CC(CC)=O)[C@H]1CC[C@H](CC(Nc2ncc(-c3ccc([C@](C4)(C[C@@]4(C)O)N)cc3)c(-c3ccccc3)c2)=O)CC1 FDFNITYLYNNGMR-VCCPSZSWSA-N 0.000 description 1
- 0 C[C@](C1)(C[C@@]1(c(c(F)c1)ccc1-c1cnc(CCNC(C[C@](CC2)CC[C@@]2N(C)C(C)=*)=O)cc1-c1ccccc1)N)O Chemical compound C[C@](C1)(C[C@@]1(c(c(F)c1)ccc1-c1cnc(CCNC(C[C@](CC2)CC[C@@]2N(C)C(C)=*)=O)cc1-c1ccccc1)N)O 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201423087 | 2014-12-23 | ||
| GB1423087.4 | 2014-12-23 | ||
| GBGB1508787.7A GB201508787D0 (en) | 2014-12-23 | 2015-05-22 | Pharmaceutically active compounds |
| GB1508787.7 | 2015-05-22 | ||
| GBGB1519919.3A GB201519919D0 (en) | 2015-11-11 | 2015-11-11 | Pharmaceutically active compounds |
| GB1519919.3 | 2015-11-11 | ||
| PCT/EP2015/081168 WO2016102672A2 (en) | 2014-12-23 | 2015-12-23 | Pharmaceutically active compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020139060A Division JP2020189880A (ja) | 2014-12-23 | 2020-08-20 | 医薬的活性化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500351A JP2018500351A (ja) | 2018-01-11 |
| JP2018500351A5 true JP2018500351A5 (https=) | 2019-01-10 |
| JP6787899B2 JP6787899B2 (ja) | 2020-11-18 |
Family
ID=56151566
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533901A Expired - Fee Related JP6787899B2 (ja) | 2014-12-23 | 2015-12-23 | 医薬的活性化合物 |
| JP2020139060A Pending JP2020189880A (ja) | 2014-12-23 | 2020-08-20 | 医薬的活性化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020139060A Pending JP2020189880A (ja) | 2014-12-23 | 2020-08-20 | 医薬的活性化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10336702B2 (https=) |
| EP (1) | EP3240784A2 (https=) |
| JP (2) | JP6787899B2 (https=) |
| KR (1) | KR20170115042A (https=) |
| CN (1) | CN107207472B (https=) |
| AU (1) | AU2015370911B2 (https=) |
| CA (1) | CA2971763A1 (https=) |
| WO (1) | WO2016102672A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017005462A (es) * | 2014-11-05 | 2017-07-28 | Flexus Biosciences Inc | Agentes inmunorreguladores. |
| CA2971763A1 (en) * | 2014-12-23 | 2016-06-30 | Bergenbio Asa | Inhibitors of akt kinase |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| WO2018130184A1 (zh) | 2017-01-13 | 2018-07-19 | 江苏恒瑞医药股份有限公司 | 1,2,4-三嗪-3-胺类衍生物、其制备方法及其在医药上的应用 |
| WO2019158070A1 (zh) * | 2018-02-15 | 2019-08-22 | 杭州阿诺生物医药科技有限公司 | A2a和/或a2b受体拮抗剂 |
| JP2021523379A (ja) | 2018-05-14 | 2021-09-02 | ベルゲンビオ アーエスアー | 血清バイオマーカー |
| CN111171065A (zh) * | 2020-02-26 | 2020-05-19 | 上海博黑生物科技有限公司 | 一种(4-(1-((叔丁氧基羰基)氨基)环丙基)苯基)硼酸酯的合成方法 |
| KR102698413B1 (ko) | 2020-05-05 | 2024-08-26 | 뉴베일런트, 아이엔씨. | 헤테로방향족 거대환식 에터 화학치료제 |
| CN115916196A (zh) * | 2020-05-05 | 2023-04-04 | 纽威伦特公司 | 杂芳族大环醚化学治疗剂 |
| KR102853833B1 (ko) * | 2020-12-21 | 2025-09-02 | 동우 화인켐 주식회사 | 양자점, 양자점 분산체, 광변환 경화성 조성물, 컬러필터, 광변환 적층기재 및 화상표시장치 |
| WO2025066935A1 (en) * | 2023-09-28 | 2025-04-03 | Hepaitech (Beijing) Biopharma Technology Co., Ltd. | Compounds, compositions and methods thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6486199B1 (en) * | 2001-06-21 | 2002-11-26 | Medicines For Malaria Venture Mmv International Centre Cointrin | Spiro and dispiro 1,2,4-trioxolane antimalarials |
| US20070185152A1 (en) | 2004-03-02 | 2007-08-09 | Smithkline Beecham Corporation | Inhibitors of akt activity |
| AU2005233584B2 (en) * | 2004-04-09 | 2010-12-09 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
| ES2270715B1 (es) | 2005-07-29 | 2008-04-01 | Laboratorios Almirall S.A. | Nuevos derivados de pirazina. |
| GB0922589D0 (en) * | 2009-12-23 | 2010-02-10 | Almac Discovery Ltd | Pharmaceutical compounds |
| AU2013355110B2 (en) | 2012-12-07 | 2017-11-09 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| CA2971763A1 (en) * | 2014-12-23 | 2016-06-30 | Bergenbio Asa | Inhibitors of akt kinase |
-
2015
- 2015-12-23 CA CA2971763A patent/CA2971763A1/en active Pending
- 2015-12-23 KR KR1020177019939A patent/KR20170115042A/ko not_active Ceased
- 2015-12-23 WO PCT/EP2015/081168 patent/WO2016102672A2/en not_active Ceased
- 2015-12-23 AU AU2015370911A patent/AU2015370911B2/en not_active Ceased
- 2015-12-23 CN CN201580075417.7A patent/CN107207472B/zh not_active Expired - Fee Related
- 2015-12-23 US US15/533,048 patent/US10336702B2/en active Active
- 2015-12-23 JP JP2017533901A patent/JP6787899B2/ja not_active Expired - Fee Related
- 2015-12-23 EP EP15823511.9A patent/EP3240784A2/en not_active Withdrawn
-
2019
- 2019-05-15 US US16/412,590 patent/US10766861B2/en not_active Expired - Fee Related
-
2020
- 2020-07-14 US US16/928,142 patent/US20210070708A1/en not_active Abandoned
- 2020-08-20 JP JP2020139060A patent/JP2020189880A/ja active Pending