JP2017538711A5 - - Google Patents
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- JP2017538711A5 JP2017538711A5 JP2017531306A JP2017531306A JP2017538711A5 JP 2017538711 A5 JP2017538711 A5 JP 2017538711A5 JP 2017531306 A JP2017531306 A JP 2017531306A JP 2017531306 A JP2017531306 A JP 2017531306A JP 2017538711 A5 JP2017538711 A5 JP 2017538711A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- chr
- alkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 CC**C(C)(CC*(C1)C(*CC(C=C2)=CC#C[C@]2C(*=CC(C2CCC*(**)(C3)C3CCCCCC2)=C)=*CC)=O)C1C(*)=O Chemical compound CC**C(C)(CC*(C1)C(*CC(C=C2)=CC#C[C@]2C(*=CC(C2CCC*(**)(C3)C3CCCCCC2)=C)=*CC)=O)C1C(*)=O 0.000 description 15
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090268P | 2014-12-10 | 2014-12-10 | |
| US62/090,268 | 2014-12-10 | ||
| US201562161658P | 2015-05-14 | 2015-05-14 | |
| US62/161,658 | 2015-05-14 | ||
| US201562164113P | 2015-05-20 | 2015-05-20 | |
| US62/164,113 | 2015-05-20 | ||
| PCT/US2015/065109 WO2016094729A1 (en) | 2014-12-10 | 2015-12-10 | Glp-1 receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017538711A JP2017538711A (ja) | 2017-12-28 |
| JP2017538711A5 true JP2017538711A5 (https=) | 2019-01-10 |
Family
ID=55069126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017531306A Pending JP2017538711A (ja) | 2014-12-10 | 2015-12-10 | Ｇｌｐ−１レセプターモジュレーター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9795613B2 (https=) |
| EP (1) | EP3230276B1 (https=) |
| JP (1) | JP2017538711A (https=) |
| KR (1) | KR102497644B1 (https=) |
| AU (1) | AU2015360364B2 (https=) |
| CA (1) | CA2969944A1 (https=) |
| ES (1) | ES2844573T3 (https=) |
| IL (1) | IL252565B (https=) |
| MX (1) | MX381977B (https=) |
| WO (1) | WO2016094729A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2937835T3 (es) * | 2017-04-28 | 2023-03-31 | Receptos Llc | Nuevos moduladores del receptor de GLP-1 |
| WO2018215070A1 (en) * | 2017-05-24 | 2018-11-29 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Dual modulators of farnesoid x receptor and soluble epoxide hydrolase |
| CN113244208B (zh) * | 2021-05-20 | 2022-07-12 | 云南中医药大学 | Hpa在制备治疗非酒精性脂肪性肝病药物中的应用 |
| WO2024210646A1 (ko) * | 2023-04-05 | 2024-10-10 | 주식회사 아울바이오 | Glp-1 수용체 작용제, gip/glp-1 수용체 이중작용제, 및 glp-1/gip/gcg 수용체 삼중작용제로 이루어진 군으로부터 선택되는 1종 이상을 포함하는 액상 제형 및 미립구 제형을 포함하는 약학 조성물 |
| TW202521533A (zh) | 2023-09-14 | 2025-06-01 | 香港商歌禮製藥(中國)有限公司 | Glp-1r 激動劑及其治療方法 |
| US12291530B1 (en) | 2023-11-24 | 2025-05-06 | Ascletis Pharma (China) Co., Limited | GLP-1R agonist and therapeutic method thereof |
| WO2025259063A1 (ko) * | 2024-06-13 | 2025-12-18 | 한미약품 주식회사 | Glp-1, gip, 및 글루카곤 수용체 모두에 활성을 갖는 삼중 활성체 및 이를 포함하는 당뇨 예방 또는 치료용 약학적 조성물 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1062206B (it) | 1974-02-01 | 1983-09-20 | Rotta Research Lab S P A A S | Derivati della tirosina attivi sulla muscolatura liscia |
| DE2423536A1 (de) | 1974-05-15 | 1975-11-27 | Bayer Ag | 3-amino-phenylessigsaeure-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als herbizide |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US6174905B1 (en) | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
| EP0996459B1 (en) | 1997-01-07 | 2005-09-21 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the reduction of food intake |
| HUP0003921A3 (en) | 1997-07-31 | 2001-03-28 | Wyeth Corp | Sulfonylated dipeptide compounds which inhibit leukocyte adhesion mediated by vla-4, pharmaceutical compositions comprising thereof and their use |
| US6583139B1 (en) * | 1997-07-31 | 2003-06-24 | Eugene D. Thorsett | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| BR9811730B1 (pt) | 1997-08-22 | 2014-04-08 | Hoffmann La Roche | Derivados de n-aroilfenilalanina, uso dos mesmos, medicamentos contendo os mesmos. |
| US6191171B1 (en) | 1997-11-20 | 2001-02-20 | Merck & Co., Inc. | Para-aminomethylaryl carboxamide derivatives |
| JP2002538081A (ja) | 1998-12-07 | 2002-11-12 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Ｇｌｐ−１の類似体 |
| NZ512663A (en) | 1999-01-14 | 2004-05-28 | Amylin Pharmaceuticals Inc | Novel exendin agonist formulations and methods of administration thereof |
| AU3487500A (en) * | 1999-02-08 | 2000-08-25 | Lion Bioscience Ag | Thiazole derivatives and combinatorial libraries thereof |
| TWI302149B (en) | 1999-09-22 | 2008-10-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
| RU2281283C2 (ru) | 2000-03-07 | 2006-08-10 | Санофи-Авентис Дойчланд Гмбх | Замещенные 3-фенил-5-алкокси-1,3,4-оксадиазол-2-оны и их применение для ингибирования гормоночувствительной липазы |
| JP4895067B2 (ja) * | 2000-09-29 | 2012-03-14 | 味の素株式会社 | 新規フェニルアラニン誘導体 |
| AU2002350217A1 (en) | 2001-12-04 | 2003-06-17 | Bristol-Myers Squibb Company | Glycinamides as factor xa inhibitors |
| AU2003211560A1 (en) * | 2002-02-20 | 2003-09-09 | Ajinomoto Co., Inc. | Novel phenylalanine derivative |
| WO2003089410A1 (en) * | 2002-04-19 | 2003-10-30 | Kyowa Hakko Kogyo Co., Ltd. | Phenylalanine derivative |
| US20070276034A1 (en) | 2002-05-31 | 2007-11-29 | Luke Esposito | Compounds, compositions and methods for the treatment of synucleinopathies |
| PT1537116E (pt) | 2002-09-04 | 2010-09-03 | Schering Corp | Pirazolopirimidinas adequadas para o tratamento de doenças cancerosas |
| WO2004022561A1 (en) | 2002-09-04 | 2004-03-18 | Schering Corporation | Pyrazolopyrimidines as cyclin-dependent kinase inhibitors |
| US20040152750A1 (en) | 2002-12-20 | 2004-08-05 | Kodra Janos Tibor | Novel glucagon antagonists |
| EA008798B1 (ru) | 2003-06-13 | 2007-08-31 | Лабораториос С.А.Л.В.А.Т., С.А. | НОВЫЕ БЕНЗАМИДЫ В КАЧЕСТВЕ PPARγ МОДУЛЯТОРОВ |
| KR101194176B1 (ko) | 2003-12-22 | 2012-10-24 | 아지노모토 가부시키가이샤 | 신규한 페닐알라닌 유도체 |
| KR20070004676A (ko) * | 2004-02-10 | 2007-01-09 | 얀센 파마슈티카 엔.브이. | 알파４ 인테그린의 길항제로서의 피리다지논 |
| WO2006117743A1 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Substituted aromatic compounds as antidiabetic agents |
| WO2006127595A1 (en) | 2005-05-23 | 2006-11-30 | Arena Pharmaceuticals, Inc. | 5-aminopyrazole carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof |
| US7825139B2 (en) | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| EP1878730A1 (en) | 2006-07-12 | 2008-01-16 | Bayer Schering Pharma Aktiengesellschaft | Substituted isoxazolines, pharmaceutical compositions containing the same, methods of preparing the same, and uses of the same |
| WO2008112939A2 (en) | 2007-03-13 | 2008-09-18 | Board Of Regents, The University Of Texas System | Composition and method for making oligo-benzamide compounds |
| EP2155720B1 (en) | 2007-06-08 | 2013-07-17 | Advinus Therapeutics Private Limited | Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application |
| WO2011094890A1 (en) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators |
| US8501982B2 (en) | 2010-06-09 | 2013-08-06 | Receptos, Inc. | GLP-1 receptor stabilizers and modulators |
| JP6007417B2 (ja) | 2011-05-31 | 2016-10-12 | レセプトス エルエルシー | 新規ｇｌｐ−１受容体安定剤および調節剤 |
| AU2012352349B2 (en) | 2011-12-12 | 2017-08-17 | Receptos Llc | Carboxylic acid derivatives comprising four cycles acting as GLP-1 receptor modulators for therapy of diseases such as diabetes |
| CN109867630A (zh) | 2013-06-11 | 2019-06-11 | 赛尔基因第二国际有限公司 | 新型glp-1受体调节剂 |
| EP3172199B1 (en) * | 2014-07-25 | 2020-07-01 | Celgene International II Sarl | Pyrimidine derivatives as glp-1 receptor modulators |
-
2015
- 2015-12-10 AU AU2015360364A patent/AU2015360364B2/en not_active Ceased
- 2015-12-10 WO PCT/US2015/065109 patent/WO2016094729A1/en not_active Ceased
- 2015-12-10 EP EP15819971.1A patent/EP3230276B1/en active Active
- 2015-12-10 CA CA2969944A patent/CA2969944A1/en not_active Abandoned
- 2015-12-10 JP JP2017531306A patent/JP2017538711A/ja active Pending
- 2015-12-10 KR KR1020177018991A patent/KR102497644B1/ko active Active
- 2015-12-10 MX MX2017007494A patent/MX381977B/es unknown
- 2015-12-10 US US14/965,777 patent/US9795613B2/en active Active
- 2015-12-10 ES ES15819971T patent/ES2844573T3/es active Active
-
2017
- 2017-05-29 IL IL252565A patent/IL252565B/en active IP Right Grant
- 2017-09-21 US US15/711,858 patent/US10034886B2/en active Active
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