JP2017538711A5 - - Google Patents
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- JP2017538711A5 JP2017538711A5 JP2017531306A JP2017531306A JP2017538711A5 JP 2017538711 A5 JP2017538711 A5 JP 2017538711A5 JP 2017531306 A JP2017531306 A JP 2017531306A JP 2017531306 A JP2017531306 A JP 2017531306A JP 2017538711 A5 JP2017538711 A5 JP 2017538711A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- chr
- alkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 CC**C(C)(CC*(C1)C(*CC(C=C2)=CC#C[C@]2C(*=CC(C2CCC*(**)(C3)C3CCCCCC2)=C)=*CC)=O)C1C(*)=O Chemical compound CC**C(C)(CC*(C1)C(*CC(C=C2)=CC#C[C@]2C(*=CC(C2CCC*(**)(C3)C3CCCCCC2)=C)=*CC)=O)C1C(*)=O 0.000 description 15
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090268P | 2014-12-10 | 2014-12-10 | |
| US62/090,268 | 2014-12-10 | ||
| US201562161658P | 2015-05-14 | 2015-05-14 | |
| US62/161,658 | 2015-05-14 | ||
| US201562164113P | 2015-05-20 | 2015-05-20 | |
| US62/164,113 | 2015-05-20 | ||
| PCT/US2015/065109 WO2016094729A1 (en) | 2014-12-10 | 2015-12-10 | Glp-1 receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017538711A JP2017538711A (ja) | 2017-12-28 |
| JP2017538711A5 true JP2017538711A5 (https=) | 2019-01-10 |
Family
ID=55069126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017531306A Pending JP2017538711A (ja) | 2014-12-10 | 2015-12-10 | Ｇｌｐ−１レセプターモジュレーター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9795613B2 (https=) |
| EP (1) | EP3230276B1 (https=) |
| JP (1) | JP2017538711A (https=) |
| KR (1) | KR102497644B1 (https=) |
| AU (1) | AU2015360364B2 (https=) |
| CA (1) | CA2969944A1 (https=) |
| ES (1) | ES2844573T3 (https=) |
| IL (1) | IL252565B (https=) |
| MX (1) | MX381977B (https=) |
| WO (1) | WO2016094729A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018200833A1 (en) * | 2017-04-28 | 2018-11-01 | Celgene International Ii Sarl | Novel glp-1 receptor modulators |
| WO2018215070A1 (en) * | 2017-05-24 | 2018-11-29 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Dual modulators of farnesoid x receptor and soluble epoxide hydrolase |
| CN113244208B (zh) * | 2021-05-20 | 2022-07-12 | 云南中医药大学 | Hpa在制备治疗非酒精性脂肪性肝病药物中的应用 |
| WO2024210646A1 (ko) * | 2023-04-05 | 2024-10-10 | 주식회사 아울바이오 | Glp-1 수용체 작용제, gip/glp-1 수용체 이중작용제, 및 glp-1/gip/gcg 수용체 삼중작용제로 이루어진 군으로부터 선택되는 1종 이상을 포함하는 액상 제형 및 미립구 제형을 포함하는 약학 조성물 |
| CN120981457A (zh) | 2023-09-14 | 2025-11-18 | 歌礼制药(中国)有限公司 | Glp-1r激动剂及其治疗方法 |
| TW202521534A (zh) | 2023-11-24 | 2025-06-01 | 香港商歌禮製藥(中國)有限公司 | Glp-1r 激動劑及其治療方法 |
| KR20250177377A (ko) * | 2024-06-13 | 2025-12-23 | 한미약품 주식회사 | Glp-1, gip, 및 글루카곤 수용체 모두에 활성을 갖는 삼중 활성체 및 이를 포함하는 당뇨 예방 또는 치료용 약학적 조성물 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1062206B (it) | 1974-02-01 | 1983-09-20 | Rotta Research Lab S P A A S | Derivati della tirosina attivi sulla muscolatura liscia |
| DE2423536A1 (de) | 1974-05-15 | 1975-11-27 | Bayer Ag | 3-amino-phenylessigsaeure-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als herbizide |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US6174905B1 (en) | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
| DE122007000044I2 (de) | 1997-01-07 | 2011-05-05 | Amylin Pharmaceuticals Inc | Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme |
| US6583139B1 (en) | 1997-07-31 | 2003-06-24 | Eugene D. Thorsett | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| PL338457A1 (en) | 1997-07-31 | 2000-11-06 | Elan Pharm Inc | Sulphonylated dipeptidic compounds capable to inhibit adhesion of leucocytes through the mediation of vla-4 |
| EP1005445B1 (en) | 1997-08-22 | 2004-05-26 | F. Hoffmann-La Roche Ag | N-alkanoylphenylalanine derivatives |
| US6191171B1 (en) | 1997-11-20 | 2001-02-20 | Merck & Co., Inc. | Para-aminomethylaryl carboxamide derivatives |
| EP1992641A3 (en) | 1998-12-07 | 2009-07-29 | Ipsen Pharma | GLP-1 analogues |
| US6902744B1 (en) | 1999-01-14 | 2005-06-07 | Amylin Pharmaceuticals, Inc. | Exendin agonist formulations and methods of administration thereof |
| EP1150565A1 (en) * | 1999-02-08 | 2001-11-07 | LION bioscience AG | Thiazole derivatives and combinatorial libraries thereof |
| TWI302149B (en) | 1999-09-22 | 2008-10-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
| TR200401217T4 (tr) | 2000-03-07 | 2004-06-21 | Aventis Pharma Deutschland Gmbh | İkameli 3-Fenil-5-Alkoksi-1,3,4-Oksdiazol-2-one (ve) hormona duyarlı lipazın önlenmesinde kullanılması |
| WO2002028830A1 (en) * | 2000-09-29 | 2002-04-11 | Ajinomoto Co.,Inc. | Novel phenylalanine derivatives |
| WO2003048081A2 (en) | 2001-12-04 | 2003-06-12 | Bristol-Myers Squibb Company | Glycinamides as factor xa inhibitors |
| EP1477482B1 (en) | 2002-02-20 | 2010-04-14 | Ajinomoto Co., Inc. | Novel phenylalanine derivative |
| JPWO2003089410A1 (ja) * | 2002-04-19 | 2005-08-25 | 協和醗酵工業株式会社 | フェニルアラニン誘導体 |
| US20070276034A1 (en) | 2002-05-31 | 2007-11-29 | Luke Esposito | Compounds, compositions and methods for the treatment of synucleinopathies |
| PL224879B1 (pl) | 2002-09-04 | 2017-02-28 | Pharmacopeia Drug Discovery Inc | Pirazolo [1,5-a] pirymidynowy związek, jego zastosowanie do wytwarzania leku oraz zawierająca go farmaceutyczna kompozycja |
| MXPA05002571A (es) | 2002-09-04 | 2005-09-08 | Schering Corp | Pirazolopirimidinas como inhibidores de cinasa dependientes de ciclina. |
| US20040152750A1 (en) | 2002-12-20 | 2004-08-05 | Kodra Janos Tibor | Novel glucagon antagonists |
| EP1644321B1 (en) | 2003-06-13 | 2011-02-09 | Laboratorios S.A.L.V.A.T., S.A. | New benzamides as ppaty modulators |
| US7345049B2 (en) | 2003-12-22 | 2008-03-18 | Ajinomoto Co., Inc. | Phenylalanine derivatives |
| CA2555594A1 (en) * | 2004-02-10 | 2005-08-25 | Janssen Pharmaceutica N.V. | Pyridazinones as antagonists of a4 integrins |
| WO2006117743A1 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Substituted aromatic compounds as antidiabetic agents |
| EP1899304A1 (en) | 2005-05-23 | 2008-03-19 | Arena Pharmaceuticals, Inc. | 5-amino-1h-pyrazole-3-carboxylic acid derivatives as agonists for the g-protein coupled receptor (gpcr) rup38 for the treatment of metabolic-related disorders thereof |
| US7825139B2 (en) | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| EP1878730A1 (en) | 2006-07-12 | 2008-01-16 | Bayer Schering Pharma Aktiengesellschaft | Substituted isoxazolines, pharmaceutical compositions containing the same, methods of preparing the same, and uses of the same |
| US7816324B2 (en) | 2007-03-13 | 2010-10-19 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by a peptide receptor |
| CA2688136A1 (en) | 2007-06-08 | 2008-12-11 | Advinus Therapeutics Private Limited | Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application |
| WO2011094890A1 (en) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators |
| JP2013530963A (ja) | 2010-06-09 | 2013-08-01 | レセプトス インコーポレイテッド | 新規のｇｌｐ−１受容体安定化薬および調節薬 |
| JP6007417B2 (ja) | 2011-05-31 | 2016-10-12 | レセプトス エルエルシー | 新規ｇｌｐ−１受容体安定剤および調節剤 |
| BR112014013925B1 (pt) | 2011-12-12 | 2022-02-22 | Receptos Llc | Compostos moduladores do receptor de glp-1 e composição e combinação farmacêutica compreendendo os ditos compostos |
| CN109867630A (zh) * | 2013-06-11 | 2019-06-11 | 赛尔基因第二国际有限公司 | 新型glp-1受体调节剂 |
| CA2955836C (en) | 2014-07-25 | 2023-02-14 | Celgene International Ii Sarl | Glp-1 receptor modulators |
-
2015
- 2015-12-10 ES ES15819971T patent/ES2844573T3/es active Active
- 2015-12-10 EP EP15819971.1A patent/EP3230276B1/en active Active
- 2015-12-10 JP JP2017531306A patent/JP2017538711A/ja active Pending
- 2015-12-10 MX MX2017007494A patent/MX381977B/es unknown
- 2015-12-10 AU AU2015360364A patent/AU2015360364B2/en not_active Ceased
- 2015-12-10 CA CA2969944A patent/CA2969944A1/en not_active Abandoned
- 2015-12-10 WO PCT/US2015/065109 patent/WO2016094729A1/en not_active Ceased
- 2015-12-10 KR KR1020177018991A patent/KR102497644B1/ko active Active
- 2015-12-10 US US14/965,777 patent/US9795613B2/en active Active
-
2017
- 2017-05-29 IL IL252565A patent/IL252565B/en active IP Right Grant
- 2017-09-21 US US15/711,858 patent/US10034886B2/en active Active
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