JP2017538692A5 - - Google Patents
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- JP2017538692A5 JP2017538692A5 JP2017528156A JP2017528156A JP2017538692A5 JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5 JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nitrogen
- alkyl
- carbon
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1421020.7A GB201421020D0 (en) | 2014-11-26 | 2014-11-26 | Compounds |
| GB1421020.7 | 2014-11-26 | ||
| GB1516059.1 | 2015-09-10 | ||
| GBGB1516059.1A GB201516059D0 (en) | 2015-09-10 | 2015-09-10 | Compounds |
| PCT/EP2015/077821 WO2016083531A1 (en) | 2014-11-26 | 2015-11-26 | Compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538692A JP2017538692A (ja) | 2017-12-28 |
| JP2017538692A5 true JP2017538692A5 (https=) | 2019-01-17 |
| JP7349773B2 JP7349773B2 (ja) | 2023-09-25 |
Family
ID=54705181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017528156A Active JP7349773B2 (ja) | 2014-11-26 | 2015-11-26 | 化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12146004B2 (https=) |
| EP (1) | EP3224273A1 (https=) |
| JP (1) | JP7349773B2 (https=) |
| CN (1) | CN107108699A (https=) |
| AU (1) | AU2015352440B2 (https=) |
| CA (1) | CA2968902C (https=) |
| TW (1) | TWI757229B (https=) |
| WO (1) | WO2016083531A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107108699A (zh) * | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| WO2018006063A1 (en) * | 2016-07-01 | 2018-01-04 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
| JP6975433B2 (ja) * | 2016-12-16 | 2021-12-01 | 中国医学科学院医薬生物技術研究所 | ポリミキシン誘導体及びその製造方法と応用 |
| AU2018359018B2 (en) * | 2017-11-02 | 2022-11-24 | The University Of Queensland | Peptide antibiotics |
| MD3810633T2 (ro) * | 2018-06-25 | 2024-05-31 | Spero Therapeutics Inc | Compuşi |
| CN111690040A (zh) * | 2019-03-12 | 2020-09-22 | 上海来益生物药物研究开发中心有限责任公司 | 多粘菌素衍生物、其制备方法和应用 |
| WO2021150792A1 (en) | 2020-01-21 | 2021-07-29 | Micurx Pharmaceuticals, Inc. | Novel compounds and composition for targeted therapy of kidney-associated cancers |
| CN111559992B (zh) * | 2020-05-29 | 2022-04-08 | 华中科技大学 | 一种2-芳基-γ-氨基丁酸衍生物的制备方法 |
| TW202233649A (zh) | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| CN117083288A (zh) * | 2021-03-31 | 2023-11-17 | 江苏奥赛康药业有限公司 | 一种多粘菌素衍生物的硫酸盐及其药物组合物 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| WO1988000950A2 (fr) | 1986-08-06 | 1988-02-11 | Fauchere Jean Luc | Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (https=) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| AU2004277977B2 (en) | 2003-09-30 | 2010-10-28 | Biomechanisms Inc. | Compositions and methods for treating burns |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US7807637B2 (en) * | 2006-08-11 | 2010-10-05 | Northern Antibiotics Oy | Polymyxin derivatives and uses thereof |
| HUE028271T2 (en) * | 2006-08-11 | 2016-12-28 | Northern Antibiotics Oy | Polymixin derivatives and their applications |
| US8329645B2 (en) | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| FI20085469A0 (fi) | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) * | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) * | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| BR112014012016A2 (pt) * | 2011-11-18 | 2017-05-16 | Cantab Anti-Infectives Ltd | compostos |
| JP6643758B2 (ja) | 2013-05-22 | 2020-02-12 | スペロ・セラピューティクス・インコーポレーテッド | 異なった抗生物質と一緒の組合せ療法におけるポリミキシン誘導体及びその使用 |
| RU2740190C2 (ru) | 2014-03-11 | 2021-01-12 | Сперо Терапьютикс, Инк. | Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками |
| US10047126B2 (en) * | 2014-04-01 | 2018-08-14 | Monash University | Polymyxin derivatives as antimicrobial compounds |
| CN107108699A (zh) * | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| WO2016166103A1 (en) | 2015-04-13 | 2016-10-20 | Xellia Pharmaceuticals Aps | Polymyxin derivatives |
| EP3356387B1 (en) | 2015-09-29 | 2024-06-26 | Monash University | Antimicrobial polymyxin derivative compounds |
| MD3810633T2 (ro) | 2018-06-25 | 2024-05-31 | Spero Therapeutics Inc | Compuşi |
-
2015
- 2015-11-26 CN CN201580072906.7A patent/CN107108699A/zh active Pending
- 2015-11-26 EP EP15801162.7A patent/EP3224273A1/en not_active Withdrawn
- 2015-11-26 CA CA2968902A patent/CA2968902C/en active Active
- 2015-11-26 WO PCT/EP2015/077821 patent/WO2016083531A1/en not_active Ceased
- 2015-11-26 US US15/529,786 patent/US12146004B2/en active Active
- 2015-11-26 JP JP2017528156A patent/JP7349773B2/ja active Active
- 2015-11-26 AU AU2015352440A patent/AU2015352440B2/en active Active
- 2015-11-26 TW TW104139459A patent/TWI757229B/zh not_active IP Right Cessation
-
2023
- 2023-04-25 US US18/139,030 patent/US20230340026A1/en not_active Abandoned
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