JP2017538692A5 - - Google Patents

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Publication number
JP2017538692A5
JP2017538692A5 JP2017528156A JP2017528156A JP2017538692A5 JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5 JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5
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JP
Japan
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group
nitrogen
alkyl
carbon
optionally substituted
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JP2017528156A
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English (en)
Japanese (ja)
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JP7349773B2 (ja
JP2017538692A (ja
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Priority claimed from GBGB1421020.7A external-priority patent/GB201421020D0/en
Priority claimed from GBGB1516059.1A external-priority patent/GB201516059D0/en
Application filed filed Critical
Priority claimed from PCT/EP2015/077821 external-priority patent/WO2016083531A1/en
Publication of JP2017538692A publication Critical patent/JP2017538692A/ja
Publication of JP2017538692A5 publication Critical patent/JP2017538692A5/ja
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Publication of JP7349773B2 publication Critical patent/JP7349773B2/ja
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JP2017528156A 2014-11-26 2015-11-26 化合物 Active JP7349773B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1421020.7A GB201421020D0 (en) 2014-11-26 2014-11-26 Compounds
GB1421020.7 2014-11-26
GBGB1516059.1A GB201516059D0 (en) 2015-09-10 2015-09-10 Compounds
GB1516059.1 2015-09-10
PCT/EP2015/077821 WO2016083531A1 (en) 2014-11-26 2015-11-26 Compounds

Publications (3)

Publication Number Publication Date
JP2017538692A JP2017538692A (ja) 2017-12-28
JP2017538692A5 true JP2017538692A5 (https=) 2019-01-17
JP7349773B2 JP7349773B2 (ja) 2023-09-25

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ID=54705181

Family Applications (1)

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JP2017528156A Active JP7349773B2 (ja) 2014-11-26 2015-11-26 化合物

Country Status (8)

Country Link
US (2) US12146004B2 (https=)
EP (1) EP3224273A1 (https=)
JP (1) JP7349773B2 (https=)
CN (1) CN107108699A (https=)
AU (1) AU2015352440B2 (https=)
CA (1) CA2968902C (https=)
TW (1) TWI757229B (https=)
WO (1) WO2016083531A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12146004B2 (en) * 2014-11-26 2024-11-19 Spero Therapeutics, Inc. Polymyxin compounds and uses thereof
WO2018006063A1 (en) * 2016-07-01 2018-01-04 Cidara Therapeutics, Inc. Compositions and methods for the treatment of bacterial infections
JP6975433B2 (ja) * 2016-12-16 2021-12-01 中国医学科学院医薬生物技術研究所 ポリミキシン誘導体及びその製造方法と応用
CN111527100A (zh) * 2017-11-02 2020-08-11 昆士兰大学 肽类抗生素
RS65128B1 (sr) * 2018-06-25 2024-02-29 Spero Therapeutics Inc Jedinjenja
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
WO2021150792A1 (en) 2020-01-21 2021-07-29 Micurx Pharmaceuticals, Inc. Novel compounds and composition for targeted therapy of kidney-associated cancers
CN111559992B (zh) * 2020-05-29 2022-04-08 华中科技大学 一种2-芳基-γ-氨基丁酸衍生物的制备方法
WO2022098950A1 (en) 2020-11-06 2022-05-12 Spero Therapeutics, Inc. Compounds
WO2022206826A1 (zh) * 2021-03-31 2022-10-06 江苏奥赛康药业有限公司 一种多粘菌素衍生物的硫酸盐及其药物组合物

Family Cites Families (27)

* Cited by examiner, † Cited by third party
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GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
AU7753787A (en) 1986-08-06 1988-02-24 Jean-Luc Fauchere Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (https=) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
CA2540742A1 (en) 2003-09-30 2005-04-14 Terry Hicks Compositions and methods for treating burns
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
BRPI0715095B8 (pt) 2006-08-11 2021-05-25 Northern Antibiotics Oy derivado de polimixina da fórmula geral (i); produto de combinação; composição farmacêutica; método para se sensibilizar bactérias gram-negativas a um agente antibacteriano; método para o desenvolvimento de antibióticos; método para a redução da toxicidade de polimixinas, octapeptinas naturais e seus derivados durante a aplicação das mesmas no tratamento de infecções em um indivíduo; método para melhorar as propriedades farmacocinéticas, de polimixinas, octapeptinas naturais e seus derivados; método para a sensibilização de bactérias gram-negativas clinicamente importantes a um complemento de mecanismo de defesa presente no soro; uso de um derivado; e processo para a preparação de um derivado de polimixina da fórmula (i).
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FI20085469A0 (fi) 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
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ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
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KR102354902B1 (ko) 2013-05-22 2022-01-24 에버레스트 메디신즈 (싱가포르) 피티이. 리미티드 폴리믹신 유도체 및 상이한 항생제와의 조합 요법에 있어서의 이들의 용도
MX359104B (es) 2014-03-11 2018-09-14 New Pharma Licence Holdings Ltd Derivados de polimixina y su uso en terapia de combinacion junto con diferentes antibioticos.
JP2017512818A (ja) * 2014-04-01 2017-05-25 モナシュ、ユニバーシティＭｏｎａｓｈ Ｕｎｉｖｅｒｓｉｔｙ 抗菌性化合物としてのポリミキシン誘導体
US12146004B2 (en) * 2014-11-26 2024-11-19 Spero Therapeutics, Inc. Polymyxin compounds and uses thereof
WO2016166103A1 (en) 2015-04-13 2016-10-20 Xellia Pharmaceuticals Aps Polymyxin derivatives
EP3356387B1 (en) 2015-09-29 2024-06-26 Monash University Antimicrobial polymyxin derivative compounds
RS65128B1 (sr) 2018-06-25 2024-02-29 Spero Therapeutics Inc Jedinjenja

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