JP2017538669A5 - - Google Patents
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- JP2017538669A5 JP2017538669A5 JP2017520986A JP2017520986A JP2017538669A5 JP 2017538669 A5 JP2017538669 A5 JP 2017538669A5 JP 2017520986 A JP2017520986 A JP 2017520986A JP 2017520986 A JP2017520986 A JP 2017520986A JP 2017538669 A5 JP2017538669 A5 JP 2017538669A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021102148A JP7253008B2 (ja) | 2014-10-24 | 2021-06-21 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
| JP2023047480A JP2023078398A (ja) | 2014-10-24 | 2023-03-24 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14190370.8A EP3012271A1 (en) | 2014-10-24 | 2014-10-24 | Method and compositions for inducing differentiation of myeloid derived suppressor cell to treat cancer and infectious diseases |
| EP14190370.8 | 2014-10-24 | ||
| PCT/IB2015/058124 WO2016063233A1 (en) | 2014-10-24 | 2015-10-21 | Method and compositions for inducing differentiation of myeloid derived suppressor cell to treat cancer and infectious diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021102148A Division JP7253008B2 (ja) | 2014-10-24 | 2021-06-21 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538669A JP2017538669A (ja) | 2017-12-28 |
| JP2017538669A5 true JP2017538669A5 (https=) | 2018-11-29 |
| JP6918279B2 JP6918279B2 (ja) | 2021-08-11 |
Family
ID=51868772
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520986A Active JP6918279B2 (ja) | 2014-10-24 | 2015-10-21 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
| JP2021102148A Active JP7253008B2 (ja) | 2014-10-24 | 2021-06-21 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
| JP2023047480A Pending JP2023078398A (ja) | 2014-10-24 | 2023-03-24 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021102148A Active JP7253008B2 (ja) | 2014-10-24 | 2021-06-21 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
| JP2023047480A Pending JP2023078398A (ja) | 2014-10-24 | 2023-03-24 | 癌および感染症の治療のために骨髄由来抑制細胞分化を誘導する方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20170247464A1 (https=) |
| EP (4) | EP3012271A1 (https=) |
| JP (3) | JP6918279B2 (https=) |
| CA (1) | CA2964203C (https=) |
| DK (2) | DK3209691T3 (https=) |
| ES (2) | ES3060595T3 (https=) |
| HU (1) | HUE050318T2 (https=) |
| PL (2) | PL3783027T3 (https=) |
| WO (1) | WO2016063233A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015109391A1 (en) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| WO2017027422A1 (en) | 2015-08-07 | 2017-02-16 | Alexo Therapeutics Inc. | Constructs having a sirp-alpha domain or variant thereof |
| EP3341015B2 (en) | 2015-08-26 | 2023-12-27 | The Board of Trustees of the Leland Stanford Junior University | Enhanced depletion of targeted cells with cd47 blockade and an immune costimulatory agonist |
| JP7078533B2 (ja) * | 2015-10-21 | 2022-05-31 | オーエスイー イムノセラピューティクス | 炎症促進性細胞へのマクロファージ分極を改変して癌を治療するための抗ＳＩＲＰａ化合物 |
| RS66062B1 (sr) | 2016-04-14 | 2024-11-29 | Ose Immunotherapeutics | Nova anti-sirpa antitela i njihove terapijske primene |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| US20190153095A1 (en) * | 2016-07-05 | 2019-05-23 | National University Corporation Kobe University | Antitumor Agent |
| JOP20190009A1 (ar) * | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| CN118027200A (zh) | 2016-12-09 | 2024-05-14 | 艾利妥 | 抗SIRPα抗体及其使用方法 |
| US11566060B2 (en) | 2017-01-05 | 2023-01-31 | Kahr Medical Ltd. | PD1-CD70 fusion protein and methods of use thereof |
| LT3565579T (lt) | 2017-01-05 | 2023-09-11 | Kahr Medical Ltd. | Pd1-41bbl sulietas baltymas ir jo panaudojimo būdai |
| PT3565828T (pt) | 2017-01-05 | 2022-02-08 | Kahr Medical Ltd | Proteína de fusão sirp1 alfa-41bbl e seus métodos de utilização |
| WO2018127918A1 (en) | 2017-01-05 | 2018-07-12 | Kahr Medical Ltd. | A sirp alpha-cd70 fusion protein and methods of use thereof |
| WO2018136659A1 (en) * | 2017-01-18 | 2018-07-26 | Nant Holdings Ip, Llc | Modulation of tumor cell susceptibility |
| US20200306300A1 (en) * | 2017-02-15 | 2020-10-01 | The Regents Of The University Of California | Compositions and methods for activating nk cells |
| JP7262440B2 (ja) | 2017-08-02 | 2023-04-21 | フェインズ セラピューティクス，インコーポレーテッド | 抗ｃｄ４７抗体及びその使用 |
| JP7395471B2 (ja) | 2017-10-13 | 2023-12-11 | オーセ イミュノセラピューティクス | 改変抗ＳＩＲＰａ抗体及びその使用 |
| AU2019233577A1 (en) | 2018-03-13 | 2020-09-03 | Ose Immunotherapeutics | Use of anti-human SIRPa v1 antibodies and method for producing anti-SIRPa v1 antibodies |
| MX2020009774A (es) | 2018-03-21 | 2020-10-08 | Alx Oncology Inc | Anticuerpos contra proteína alfa reguladora de señal y métodos de uso. |
| EP3802602A1 (en) | 2018-05-25 | 2021-04-14 | Alector LLC | Anti-sirpa antibodies and methods of use thereof |
| US11759485B2 (en) | 2018-06-14 | 2023-09-19 | Meiji Co., Ltd. | Composition for enhancing immune checkpoint blockade therapy |
| US12134638B2 (en) | 2018-07-11 | 2024-11-05 | Kahr Medical Ltd. | SIRPalpha-4-1BBL variant fusion protein and methods of use thereof |
| KR20210044221A (ko) | 2018-07-11 | 2021-04-22 | 카 메디컬 리미티드 | Pd1-4-1bbl 변이체 융합 단백질 및 이의 사용 방법 |
| US11591390B2 (en) | 2018-09-27 | 2023-02-28 | Celgene Corporation | SIRP-α binding proteins and methods of use thereof |
| SG11202102851XA (en) | 2018-09-27 | 2021-04-29 | Celgene Corp | SIRPa BINDING PROTEINS AND METHODS OF USE THEREOF |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| BR112021007286A2 (pt) * | 2018-10-19 | 2021-07-27 | Ohio State Innovation Foundation | células furtivas terapêuticas nanoprojetadas |
| BR112021024003A2 (pt) | 2019-05-31 | 2022-04-19 | Alx Oncology Inc | Métodos de tratamento de câncer com fusão sirp alfa-fc em combinação com um inibidor de checkpoint imunológico |
| CN114206912B (zh) | 2019-06-07 | 2025-02-11 | Alx肿瘤生物技术公司 | 用于在血清学测定中减少结合cd47的药物的干扰的方法和试剂 |
| AU2020394204A1 (en) | 2019-11-27 | 2022-06-02 | ALX Oncology Inc. | Combination therapies for treating cancer |
| US12343377B2 (en) | 2020-06-01 | 2025-07-01 | ALX Oncology Inc. | Combination therapies comprising a hypomethylation agent for treating cancer |
| CN111808800B (zh) * | 2020-07-20 | 2022-08-26 | 中南大学湘雅二医院 | 一种体外诱导免疫抑制性髓系抑制细胞及其制备和应用 |
| WO2022120286A1 (en) | 2020-12-06 | 2022-06-09 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
| WO2023020459A1 (zh) | 2021-08-17 | 2023-02-23 | 杭州九源基因工程有限公司 | 靶向SIRPα的单克隆抗体及其用途 |
| JP2025523369A (ja) | 2022-06-01 | 2025-07-23 | エーエルエックス オンコロジー インコーポレイテッド | 尿路上皮癌腫を治療するための併用療法 |
| EP4619435A1 (en) | 2022-11-16 | 2025-09-24 | Boehringer Ingelheim International GmbH | Predictive efficacy biomarkers for anti-sirpa antibodies |
| CN115896015B (zh) * | 2023-02-08 | 2023-09-29 | 上海诚益生物科技有限公司 | 一种髓系来源抑制性细胞的体外培养方法 |
| CN117054649A (zh) * | 2023-08-04 | 2023-11-14 | 广州中医药大学第一附属医院 | 一种慢性萎缩性胃炎向胃癌转化标志物及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1048299A1 (en) | 1999-04-28 | 2000-11-02 | Faculteit der Geneeskunde van de Vrije Universiteit | Method for inhibiting cell functioning for use in anti-inflammatory and anti-tumour therapies |
| JP3936673B2 (ja) | 2003-06-02 | 2007-06-27 | 国立大学法人群馬大学 | Ｃｄ４７部分ペプチドと抗ｓｈｐｓ−１モノクロナール抗体 |
| EP2630966B1 (en) * | 2007-10-12 | 2017-04-19 | Massachusetts Institute of Technology | Vaccine nanotechnology |
| AU2009205665B2 (en) * | 2008-01-15 | 2013-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for manipulating phagocytosis mediated by CD47 |
| EP2111869A1 (en) | 2008-04-23 | 2009-10-28 | Stichting Sanquin Bloedvoorziening | Compositions and methods to enhance the immune system |
| PL2995315T3 (pl) | 2009-05-15 | 2024-04-22 | University Health Network | Kompozycje i sposoby leczenia nowotworów hematologicznych celujące w oddziaływanie sirp alfa-cd47 |
| GB201015765D0 (en) * | 2010-09-21 | 2010-10-27 | Immatics Biotechnologies Gmbh | Use of myeloid cell biomarkers for the diagnosis of cancer |
| EP3682896A1 (en) * | 2011-04-28 | 2020-07-22 | University of Southern California | Human myeloid derived suppressor cell cancer markers |
| WO2013056352A1 (en) * | 2011-10-19 | 2013-04-25 | University Health Network | Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers |
| SI2804617T1 (sl) | 2012-01-17 | 2020-10-30 | The Board Of Trustees Of The Leland Stanford Junior University | Visokoafinitetni SIRP-alfa reagenti |
| CN105101997B (zh) * | 2013-02-06 | 2018-11-09 | 印希彼有限合伙公司 | 不减少血小板和不减少血红细胞的cd47抗体及其使用方法 |
| AU2015229448B2 (en) | 2014-03-11 | 2020-09-03 | The Board Of Trustees Of The Leland Stanford Junior University | Anti SIRP-alpha antibodies and Bi-specific Macrophage Enhancing antibodies |
-
2014
- 2014-10-24 EP EP14190370.8A patent/EP3012271A1/en not_active Withdrawn
-
2015
- 2015-10-21 DK DK15794641.9T patent/DK3209691T3/da active
- 2015-10-21 EP EP25219878.3A patent/EP4691569A3/en active Pending
- 2015-10-21 US US15/518,803 patent/US20170247464A1/en not_active Abandoned
- 2015-10-21 PL PL20177260.5T patent/PL3783027T3/pl unknown
- 2015-10-21 PL PL15794641T patent/PL3209691T3/pl unknown
- 2015-10-21 JP JP2017520986A patent/JP6918279B2/ja active Active
- 2015-10-21 EP EP20177260.5A patent/EP3783027B1/en active Active
- 2015-10-21 DK DK20177260.5T patent/DK3783027T3/da active
- 2015-10-21 EP EP15794641.9A patent/EP3209691B1/en not_active Revoked
- 2015-10-21 CA CA2964203A patent/CA2964203C/en active Active
- 2015-10-21 ES ES20177260T patent/ES3060595T3/es active Active
- 2015-10-21 ES ES15794641T patent/ES2817074T3/es active Active
- 2015-10-21 HU HUE15794641A patent/HUE050318T2/hu unknown
- 2015-10-21 WO PCT/IB2015/058124 patent/WO2016063233A1/en not_active Ceased
-
2021
- 2021-06-21 JP JP2021102148A patent/JP7253008B2/ja active Active
-
2022
- 2022-05-20 US US17/749,856 patent/US20220281993A1/en not_active Abandoned
-
2023
- 2023-03-24 JP JP2023047480A patent/JP2023078398A/ja active Pending
-
2024
- 2024-04-25 US US18/645,607 patent/US20240294659A1/en active Pending
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