JP2017538483A5 - - Google Patents
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- JP2017538483A5 JP2017538483A5 JP2017527796A JP2017527796A JP2017538483A5 JP 2017538483 A5 JP2017538483 A5 JP 2017538483A5 JP 2017527796 A JP2017527796 A JP 2017527796A JP 2017527796 A JP2017527796 A JP 2017527796A JP 2017538483 A5 JP2017538483 A5 JP 2017538483A5
- Authority
- JP
- Japan
- Prior art keywords
- fibers
- copolymer
- range
- poly
- implant according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000835 fiber Substances 0.000 claims 26
- 239000007943 implant Substances 0.000 claims 25
- 229920001577 copolymer Polymers 0.000 claims 15
- 229920000642 polymer Polymers 0.000 claims 12
- 239000011173 biocomposite Substances 0.000 claims 8
- 229920001432 poly(L-lactide) Polymers 0.000 claims 8
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 7
- 239000002131 composite material Substances 0.000 claims 7
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical group CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 7
- 239000012783 reinforcing fiber Substances 0.000 claims 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 6
- RBMHUYBJIYNRLY-UHFFFAOYSA-N 2-[(1-carboxy-1-hydroxyethyl)-hydroxyphosphoryl]-2-hydroxypropanoic acid Chemical compound OC(=O)C(O)(C)P(O)(=O)C(C)(O)C(O)=O RBMHUYBJIYNRLY-UHFFFAOYSA-N 0.000 claims 5
- 239000011159 matrix material Substances 0.000 claims 5
- 229920001434 poly(D-lactide) Polymers 0.000 claims 5
- 229920000747 poly(lactic acid) Polymers 0.000 claims 5
- OZJPLYNZGCXSJM-UHFFFAOYSA-N 5-valerolactone Chemical compound O=C1CCCCO1 OZJPLYNZGCXSJM-UHFFFAOYSA-N 0.000 claims 4
- 229920000331 Polyhydroxybutyrate Polymers 0.000 claims 4
- -1 etc.) Chemical compound 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000005015 poly(hydroxybutyrate) Substances 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 3
- 229920000954 Polyglycolide Polymers 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 3
- 239000011707 mineral Substances 0.000 claims 3
- 229920001610 polycaprolactone Polymers 0.000 claims 3
- 230000002787 reinforcement Effects 0.000 claims 3
- 239000000377 silicon dioxide Substances 0.000 claims 3
- 229920001897 terpolymer Polymers 0.000 claims 3
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims 2
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 229910004298 SiO 2 Inorganic materials 0.000 claims 2
- 229920002988 biodegradable polymer Polymers 0.000 claims 2
- 239000004621 biodegradable polymer Substances 0.000 claims 2
- 239000001913 cellulose Chemical class 0.000 claims 2
- 229920002678 cellulose Chemical class 0.000 claims 2
- 235000010980 cellulose Nutrition 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229920000117 poly(dioxanone) Polymers 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 239000004814 polyurethane Substances 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims 2
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- VKSWWACDZPRJAP-UHFFFAOYSA-N 1,3-dioxepan-2-one Chemical compound O=C1OCCCCO1 VKSWWACDZPRJAP-UHFFFAOYSA-N 0.000 claims 1
- SJDLIJNQXLJBBE-UHFFFAOYSA-N 1,4-dioxepan-2-one Chemical compound O=C1COCCCO1 SJDLIJNQXLJBBE-UHFFFAOYSA-N 0.000 claims 1
- AOLNDUQWRUPYGE-UHFFFAOYSA-N 1,4-dioxepan-5-one Chemical compound O=C1CCOCCO1 AOLNDUQWRUPYGE-UHFFFAOYSA-N 0.000 claims 1
- IJVRPNIWWODHHA-UHFFFAOYSA-N 2-cyanoprop-2-enoic acid Chemical compound OC(=O)C(=C)C#N IJVRPNIWWODHHA-UHFFFAOYSA-N 0.000 claims 1
- ALRHLSYJTWAHJZ-UHFFFAOYSA-M 3-hydroxypropionate Chemical compound OCCC([O-])=O ALRHLSYJTWAHJZ-UHFFFAOYSA-M 0.000 claims 1
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 claims 1
- FMHKPLXYWVCLME-UHFFFAOYSA-N 4-hydroxy-valeric acid Chemical compound CC(O)CCC(O)=O FMHKPLXYWVCLME-UHFFFAOYSA-N 0.000 claims 1
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 1
- 229930185605 Bisphenol Natural products 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229920002732 Polyanhydride Polymers 0.000 claims 1
- 239000004642 Polyimide Substances 0.000 claims 1
- 229920001710 Polyorthoester Polymers 0.000 claims 1
- 229920000388 Polyphosphate Polymers 0.000 claims 1
- 229920002472 Starch Chemical class 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims 1
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 229960005188 collagen Drugs 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229920000578 graft copolymer Polymers 0.000 claims 1
- 229920001519 homopolymer Polymers 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 239000001630 malic acid Substances 0.000 claims 1
- 150000002905 orthoesters Chemical class 0.000 claims 1
- 235000006408 oxalic acid Nutrition 0.000 claims 1
- 229920001308 poly(aminoacid) Polymers 0.000 claims 1
- 239000005014 poly(hydroxyalkanoate) Chemical class 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 239000002745 poly(ortho ester) Substances 0.000 claims 1
- 229920000515 polycarbonate Polymers 0.000 claims 1
- 239000004417 polycarbonate Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920006149 polyester-amide block copolymer Polymers 0.000 claims 1
- 229920002643 polyglutamic acid Polymers 0.000 claims 1
- 229920000903 polyhydroxyalkanoate Chemical class 0.000 claims 1
- 229920001721 polyimide Polymers 0.000 claims 1
- 239000001205 polyphosphate Substances 0.000 claims 1
- 235000011176 polyphosphates Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 229920005604 random copolymer Polymers 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462096932P | 2014-12-26 | 2014-12-26 | |
| US62/096,932 | 2014-12-26 | ||
| PCT/IB2015/002602 WO2016103049A1 (en) | 2014-12-26 | 2015-12-28 | Continuous-fiber reinforced biocomposite medical implants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538483A JP2017538483A (ja) | 2017-12-28 |
| JP2017538483A5 true JP2017538483A5 (https=) | 2019-02-07 |
| JP6822954B2 JP6822954B2 (ja) | 2021-01-27 |
Family
ID=56149337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527796A Active JP6822954B2 (ja) | 2014-12-26 | 2015-12-28 | 連続繊維で補強されたバイオコンポジットの医療用インプラント |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10926004B2 (https=) |
| EP (2) | EP3236866B1 (https=) |
| JP (1) | JP6822954B2 (https=) |
| KR (1) | KR102581716B1 (https=) |
| CN (1) | CN107106210B (https=) |
| AU (1) | AU2015370600B2 (https=) |
| BR (1) | BR112017012508B1 (https=) |
| CA (1) | CA2971990C (https=) |
| ES (1) | ES2763928T3 (https=) |
| FI (1) | FI3628249T3 (https=) |
| IL (1) | IL253171B (https=) |
| MX (1) | MX2017008530A (https=) |
| SG (2) | SG11201702962QA (https=) |
| WO (1) | WO2016103049A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US20120101593A1 (en) | 2010-10-20 | 2012-04-26 | BIOS2 Medical, Inc. | Implantable polymer for bone and vascular lesions |
| US20210308264A1 (en) * | 2010-10-20 | 2021-10-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2013130877A1 (en) | 2012-02-29 | 2013-09-06 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, including the use of composite implants |
| EP3795635A1 (en) | 2013-05-23 | 2021-03-24 | 206 ORTHO, Inc. | Apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| KR102504497B1 (ko) | 2014-09-07 | 2023-02-27 | 오씨오 리미티드 | 이방성 생체복합재료 물질, 이를 포함하는 의학적 이식물 및 이의 치료방법 |
| EP3236866B1 (en) | 2014-12-26 | 2019-11-13 | Ossio Ltd | Continuous-fiber reinforced biocomposite medical implants |
| WO2017155956A1 (en) * | 2016-03-07 | 2017-09-14 | Ossio Ltd | Surface treated biocomposite material, medical implants comprising same and methods of treatment thereof |
| JP2019518568A (ja) | 2016-06-27 | 2019-07-04 | オッシオ リミテッド | 高い鉱物含有量を有する繊維強化バイオ複合材料の医療用インプラント |
| US11540866B2 (en) * | 2017-03-29 | 2023-01-03 | Bone Solutions, Inc. | Implant of osteostimulative material |
| US10722280B2 (en) * | 2017-03-29 | 2020-07-28 | Bone Solutions, Inc. | Implant of osteostimulative material |
| KR102758177B1 (ko) * | 2017-09-07 | 2025-01-22 | 오씨오 리미티드 | 섬유 강화 생체복합재 나사산 형성 임플란트 |
| CN107596429B (zh) * | 2017-09-29 | 2020-09-29 | 南京轩凯生物科技有限公司 | 一种血液蛋白响应型γ-聚谷氨酸水凝胶止血材料及其制备方法和应用 |
| ES2871104T3 (es) * | 2017-10-16 | 2021-10-28 | Arctic Biomaterials Oy | Implantes bioabsorbibles ortopédicos |
| DE102017009989A1 (de) * | 2017-10-26 | 2019-05-02 | Carl Freudenberg Kg | Biokompatibles Verbundmaterial zum Einbringen in einen menschlichen Körper |
| JP7307960B2 (ja) * | 2017-12-20 | 2023-07-13 | オッシオ リミテッド | 繊維束補強生体複合医療用インプラント |
| CN108434534B (zh) * | 2018-06-11 | 2020-05-19 | 浙江大学 | 一种具有仿钢筋-混凝土结构的高强度氧化石墨烯/壳聚糖复合接骨钉材料及其制备方法 |
| ES2935496T3 (es) * | 2019-08-21 | 2023-03-07 | Bioretec Oy | Material compuesto, implante que lo comprende, uso del material compuesto y método para preparar un dispositivo médico |
| US20210146016A1 (en) | 2019-11-15 | 2021-05-20 | Evonik Operations Gmbh | Fiber reinforced compositions and methods of manufacture for medical device applications |
| GB2597063A (en) * | 2020-07-09 | 2022-01-19 | Invibio Device Component Mfg Limited | Composite materials |
| JP7446965B2 (ja) * | 2020-09-29 | 2024-03-11 | グローブライド株式会社 | 脊椎固定具用ロッド |
| US12383246B2 (en) | 2020-10-12 | 2025-08-12 | Abbott Cardiovascular Systems, Inc. | Vessel closure device with improved safety and tract hemostasis |
| CN112370634B (zh) * | 2020-11-03 | 2023-04-25 | 山东华安生物科技有限公司 | 一种复合管及其制备方法和应用 |
| CN113398325B (zh) * | 2021-06-11 | 2023-04-21 | 叶川 | 用于增强螺钉稳定性和诱导骨再生的纤维膜及其制备方法 |
| WO2023002471A1 (en) * | 2021-07-19 | 2023-01-26 | Ossio Ltd. | Fiber-reinforced biocomposite medical implants with deformable protrusions and methods of use thereof |
| IL294542B1 (en) | 2021-07-19 | 2026-02-01 | Ossio Ltd | Device with an implant insertion tube with adjustable insertion depth |
| JP7626681B2 (ja) * | 2021-08-05 | 2025-02-04 | グローブライド株式会社 | 脊椎固定具用ロッド |
| US12318124B2 (en) * | 2021-11-29 | 2025-06-03 | Warsaw Orthopedic, Inc. | Continuous fiber bone screw and method of manufacture |
| WO2023225649A1 (en) * | 2022-05-19 | 2023-11-23 | 206 Ortho, Inc. | Degradable composite and method of fabrication |
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