JP2017537126A5 - - Google Patents
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- JP2017537126A5 JP2017537126A5 JP2017530728A JP2017530728A JP2017537126A5 JP 2017537126 A5 JP2017537126 A5 JP 2017537126A5 JP 2017530728 A JP2017530728 A JP 2017530728A JP 2017530728 A JP2017530728 A JP 2017530728A JP 2017537126 A5 JP2017537126 A5 JP 2017537126A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- small cell
- lung cancer
- cell lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410749394 | 2014-12-09 | ||
| CN201410749394.0 | 2014-12-09 | ||
| PCT/CN2015/096777 WO2016091168A1 (zh) | 2014-12-09 | 2015-12-09 | 抗非小细胞肺癌的喹啉衍生物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537126A JP2017537126A (ja) | 2017-12-14 |
| JP2017537126A5 true JP2017537126A5 (enExample) | 2020-03-05 |
| JP6865684B2 JP6865684B2 (ja) | 2021-04-28 |
Family
ID=56106719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017530728A Active JP6865684B2 (ja) | 2014-12-09 | 2015-12-09 | 非小細胞肺癌に対するキノリン誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10307412B2 (enExample) |
| EP (1) | EP3231797B1 (enExample) |
| JP (1) | JP6865684B2 (enExample) |
| CN (1) | CN107001326B (enExample) |
| AU (1) | AU2015360095B2 (enExample) |
| ES (1) | ES2793286T3 (enExample) |
| WO (1) | WO2016091168A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311029A (zh) | 2014-06-06 | 2016-02-10 | 正大天晴药业集团股份有限公司 | 抗肿瘤活性的喹啉衍生物 |
| CN105311030B (zh) * | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
| CN107001326B (zh) | 2014-12-09 | 2020-05-05 | 正大天晴药业集团股份有限公司 | 抗非小细胞肺癌的喹啉衍生物 |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| JP6913955B2 (ja) | 2015-07-11 | 2021-08-04 | アドヴェンチェン ファーマスーティカルズ，エルエルシー | ＰＩ３Ｋ／ｍＴＯＲ阻害剤としての溶融キノリン化合物 |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
| WO2019166012A1 (zh) | 2018-03-02 | 2019-09-06 | 正大天晴药业集团股份有限公司 | 作为c-Met激酶抑制剂的化合物的结晶及其制备方法和用途 |
| CN116440134A (zh) * | 2018-05-22 | 2023-07-18 | 正大天晴药业集团股份有限公司 | 用于治疗非小细胞肺癌的喹啉衍生物 |
| CA3106055A1 (en) * | 2018-07-18 | 2020-01-23 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Therapeutic combination of quinoline derivative and antibody |
| CN112638385B (zh) * | 2018-09-18 | 2023-03-31 | 正大天晴药业集团股份有限公司 | 用于治疗脑肿瘤的喹啉衍生物 |
| US20220031689A1 (en) * | 2018-09-18 | 2022-02-03 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative used for treating small cell lung cancer |
| KR20210151806A (ko) * | 2019-03-07 | 2021-12-14 | 어드밴첸 파마수티컬스, 엘엘씨 | 암 치료를 위해 순차적으로 카테켄티닙 (안로티닙)과 표준 화학요법 또는 면역요법을 조합하여 사용 |
| CN113613674B (zh) * | 2019-03-15 | 2024-11-05 | 正大天晴药业集团股份有限公司 | 治疗小细胞肺癌的联用药物组合物 |
| CN112274511B (zh) * | 2019-07-22 | 2024-04-02 | 正大天晴药业集团股份有限公司 | 用于治疗移植物抗宿主病的喹啉衍生物 |
| JP2022550037A (ja) * | 2019-09-25 | 2022-11-30 | デバイオファーム インターナショナル エス．エー． | 局所進行性扁平上皮癌を有する患者の治療のための投与レジメン |
| CN114761010B (zh) * | 2019-11-25 | 2024-04-16 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物或其盐的联用药物组合物及其用途 |
| WO2021143928A1 (zh) * | 2020-01-19 | 2021-07-22 | 正大天晴药业集团股份有限公司 | 用于治疗类风湿性关节炎的喹啉衍生物 |
| CN120154618B (zh) * | 2025-05-15 | 2025-11-18 | 正大天晴药业集团股份有限公司 | 格索雷塞用于治疗肺癌的用途或其药物组合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| MX2009008486A (es) | 2007-02-20 | 2009-08-20 | Novartis Ag | Imidazoquinolinas como inhibidores dobles de cinasa de lipido y mtor. |
| US8148532B2 (en) | 2007-03-14 | 2012-04-03 | Guoqing Paul Chen | Spiro substituted compounds as angiogenesis inhibitors |
| US8163923B2 (en) | 2007-03-14 | 2012-04-24 | Advenchen Laboratories, Llc | Spiro substituted compounds as angiogenesis inhibitors |
| US20110212053A1 (en) | 2008-06-19 | 2011-09-01 | Dapeng Qian | Phosphatidylinositol 3 kinase inhibitors |
| IT1393351B1 (it) | 2009-03-16 | 2012-04-20 | Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa | Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi |
| CN102344438B (zh) * | 2010-08-01 | 2014-02-19 | 正大天晴药业集团股份有限公司 | 喹啉衍生物的结晶及其制备方法 |
| US9550781B2 (en) * | 2011-11-14 | 2017-01-24 | Centaurus Biopharma Co., Ltd. | Kinase modulating compounds, compositions containing the same and use thereof |
| CA2896898A1 (en) | 2013-01-18 | 2014-07-24 | Advenchen Pharmaceuticals, LLC | Process for preparing the anti-tumor agent 6-(7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-n-methyl-1-naphthamide and its crystalline |
| CN104513229A (zh) * | 2013-09-28 | 2015-04-15 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物及其制备方法 |
| CN105311030B (zh) | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
| CN105311029A (zh) | 2014-06-06 | 2016-02-10 | 正大天晴药业集团股份有限公司 | 抗肿瘤活性的喹啉衍生物 |
| AU2015290007B2 (en) | 2014-07-14 | 2019-11-21 | Advenchen Pharmaceuticals, Nanjing Ltd. | Fused quinoline compunds as pi3k, mTor inhibitors |
| CN107001326B (zh) | 2014-12-09 | 2020-05-05 | 正大天晴药业集团股份有限公司 | 抗非小细胞肺癌的喹啉衍生物 |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| JP6913955B2 (ja) | 2015-07-11 | 2021-08-04 | アドヴェンチェン ファーマスーティカルズ，エルエルシー | ＰＩ３Ｋ／ｍＴＯＲ阻害剤としての溶融キノリン化合物 |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
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2015
- 2015-12-09 CN CN201580066275.8A patent/CN107001326B/zh active Active
- 2015-12-09 WO PCT/CN2015/096777 patent/WO2016091168A1/zh not_active Ceased
- 2015-12-09 US US15/533,873 patent/US10307412B2/en active Active
- 2015-12-09 ES ES15867543T patent/ES2793286T3/es active Active
- 2015-12-09 JP JP2017530728A patent/JP6865684B2/ja active Active
- 2015-12-09 EP EP15867543.9A patent/EP3231797B1/en active Active
- 2015-12-09 AU AU2015360095A patent/AU2015360095B2/en active Active
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2019
- 2019-04-12 US US16/383,288 patent/US10888559B2/en active Active