CN112105361A - 用于治疗非小细胞肺癌的喹啉衍生物 - Google Patents
用于治疗非小细胞肺癌的喹啉衍生物 Download PDFInfo
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- CN112105361A CN112105361A CN201980033590.9A CN201980033590A CN112105361A CN 112105361 A CN112105361 A CN 112105361A CN 201980033590 A CN201980033590 A CN 201980033590A CN 112105361 A CN112105361 A CN 112105361A
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
一种用于治疗非小细胞肺癌的喹啉衍生物。用于治疗非小细胞肺癌的方法，所述方法包括给予需要治疗的患者治疗有效量的喹唑啉化合物或其药学上可接受的盐，其中所述的非小细胞肺癌为EGFR突变的非小细胞肺癌和/或ALK阳性的非小细胞肺癌。
Description
PCT国内申请，说明书已公开。
Claims (7)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202310227490.8A CN116440134A (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018104941214 | 2018-05-22 | ||
| CN201810494121 | 2018-05-22 | ||
| PCT/CN2019/087721 WO2019223672A1 (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
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| CN202310227490.8A Division CN116440134A (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
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| CN112105361A true CN112105361A (zh) | 2020-12-18 |
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| CN202310227490.8A Pending CN116440134A (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
| CN201980033590.9A Pending CN112105361A (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
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| CN202310227490.8A Pending CN116440134A (zh) | 2018-05-22 | 2019-05-21 | 用于治疗非小细胞肺癌的喹啉衍生物 |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN116440134A (zh) |
| WO (1) | WO2019223672A1 (zh) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101809012A (zh) * | 2007-03-14 | 2010-08-18 | 南京爱德程医药科技有限公司 | 作为血管生成抑制剂的螺取代化合物 |
| CN106999484A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 治疗非小细胞肺癌的喹啉衍生物 |
| CN107001326A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 抗非小细胞肺癌的喹啉衍生物 |
-
2019
- 2019-05-21 CN CN202310227490.8A patent/CN116440134A/zh active Pending
- 2019-05-21 WO PCT/CN2019/087721 patent/WO2019223672A1/zh active Application Filing
- 2019-05-21 CN CN201980033590.9A patent/CN112105361A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101809012A (zh) * | 2007-03-14 | 2010-08-18 | 南京爱德程医药科技有限公司 | 作为血管生成抑制剂的螺取代化合物 |
| CN106999484A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 治疗非小细胞肺癌的喹啉衍生物 |
| CN107001326A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 抗非小细胞肺癌的喹啉衍生物 |
Non-Patent Citations (2)
| Title |
|---|
| ANLOTINIB: "anlotinib", 《STN结构检索》 * |
| 中国医学论坛报今日肿瘤: "安罗替尼奏响中国强音：ALTER0303研究系列后续数据分析在2017年WCLC中展示", 《网页新闻》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116440134A (zh) | 2023-07-18 |
| WO2019223672A1 (zh) | 2019-11-28 |
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Application publication date: 20201218 |