JP2017537056A5 - - Google Patents
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- Publication number
- JP2017537056A5 JP2017537056A5 JP2017515897A JP2017515897A JP2017537056A5 JP 2017537056 A5 JP2017537056 A5 JP 2017537056A5 JP 2017515897 A JP2017515897 A JP 2017515897A JP 2017515897 A JP2017515897 A JP 2017515897A JP 2017537056 A5 JP2017537056 A5 JP 2017537056A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- substituted
- pyrazol
- compound according
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2014/090064 | 2014-10-31 | ||
| CN2014090064 | 2014-10-31 | ||
| PCT/EP2015/074923 WO2016066663A1 (en) | 2014-10-31 | 2015-10-28 | Pyrazolyl-3,4-dihydroquinolin-2-one aldosterone synthase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537056A JP2017537056A (ja) | 2017-12-14 |
| JP2017537056A5 true JP2017537056A5 (enExample) | 2018-12-06 |
| JP6669734B2 JP6669734B2 (ja) | 2020-03-18 |
Family
ID=54356342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515897A Active JP6669734B2 (ja) | 2014-10-31 | 2015-10-28 | ピラゾリル−３，４−ジドヒドロキノリン−２−オン・アルドステロン合成酵素阻害剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9796702B2 (enExample) |
| EP (1) | EP3212631B1 (enExample) |
| JP (1) | JP6669734B2 (enExample) |
| CN (1) | CN106660998B (enExample) |
| WO (1) | WO2016066663A1 (enExample) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5739338A (en) * | 1996-11-05 | 1998-04-14 | Allergan | N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity |
| DE102008022221A1 (de) * | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| CA2846785C (en) * | 2011-09-15 | 2020-09-22 | F. Hoffmann-La Roche Ag | New dihydroquinoline-2-one derivatives |
| US9353081B2 (en) * | 2011-09-23 | 2016-05-31 | Hoffmann-La Roche Inc. | Bicyclic dihydroquinoline-2-one derivatives |
| WO2014135561A1 (en) * | 2013-03-08 | 2014-09-12 | F. Hoffmann-La Roche Ag | New dihydroquinoline-2-one derivatives as aldosterone synthase (cyp1 1 b2 or cyp1 1 b1 ) inhibitors |
| KR20150119207A (ko) * | 2013-03-14 | 2015-10-23 | 에프. 호프만-라 로슈 아게 | 알도스테론 신타제 억제제로서 사용하기 위한 다이하이드로퀴놀린-2-온 유도체 |
-
2015
- 2015-10-28 JP JP2017515897A patent/JP6669734B2/ja active Active
- 2015-10-28 CN CN201580043590.9A patent/CN106660998B/zh active Active
- 2015-10-28 WO PCT/EP2015/074923 patent/WO2016066663A1/en not_active Ceased
- 2015-10-28 EP EP15785139.5A patent/EP3212631B1/en active Active
-
2017
- 2017-04-27 US US15/498,960 patent/US9796702B2/en active Active
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