JP2017533888A5 - - Google Patents
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- JP2017533888A5 JP2017533888A5 JP2017515768A JP2017515768A JP2017533888A5 JP 2017533888 A5 JP2017533888 A5 JP 2017533888A5 JP 2017515768 A JP2017515768 A JP 2017515768A JP 2017515768 A JP2017515768 A JP 2017515768A JP 2017533888 A5 JP2017533888 A5 JP 2017533888A5
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- 125000003275 alpha amino acid group Chemical group 0.000 claims description 78
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- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical group C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 7
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- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 claims 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
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- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 claims 1
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- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
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- ANGKOCUUWGHLCE-HKUYNNGSSA-N [(3s)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2r)-2-cyclopentyl-2-hydroxy-2-phenylacetate Chemical compound C1[N+](C)(C)CC[C@@H]1OC(=O)[C@](O)(C=1C=CC=CC=1)C1CCCC1 ANGKOCUUWGHLCE-HKUYNNGSSA-N 0.000 claims 1
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- MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 claims 1
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- QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 claims 1
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020002597A JP6916319B2 (ja) | 2014-09-23 | 2020-01-10 | 抗ｉｌ−２５抗体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462054167P | 2014-09-23 | 2014-09-23 | |
| US62/054,167 | 2014-09-23 | ||
| PCT/US2015/051407 WO2016049000A2 (en) | 2014-09-23 | 2015-09-22 | Anti-il-25 antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020002597A Division JP6916319B2 (ja) | 2014-09-23 | 2020-01-10 | 抗ｉｌ−２５抗体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533888A JP2017533888A (ja) | 2017-11-16 |
| JP2017533888A5 true JP2017533888A5 (enExample) | 2018-10-25 |
| JP6694877B2 JP6694877B2 (ja) | 2020-05-20 |
Family
ID=54207847
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515768A Active JP6694877B2 (ja) | 2014-09-23 | 2015-09-22 | 抗ｉｌ−２５抗体およびその使用 |
| JP2020002597A Active JP6916319B2 (ja) | 2014-09-23 | 2020-01-10 | 抗ｉｌ−２５抗体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020002597A Active JP6916319B2 (ja) | 2014-09-23 | 2020-01-10 | 抗ｉｌ−２５抗体およびその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9840557B2 (enExample) |
| EP (1) | EP3197914B1 (enExample) |
| JP (2) | JP6694877B2 (enExample) |
| KR (1) | KR102576368B1 (enExample) |
| CN (1) | CN107207589B (enExample) |
| AU (1) | AU2015321517B2 (enExample) |
| CA (1) | CA2961517C (enExample) |
| CL (2) | CL2017000703A1 (enExample) |
| CO (1) | CO2017003072A2 (enExample) |
| EA (1) | EA036658B1 (enExample) |
| IL (1) | IL251001B (enExample) |
| MA (1) | MA40106A1 (enExample) |
| MX (1) | MX2017003841A (enExample) |
| MY (1) | MY185832A (enExample) |
| PH (1) | PH12017500403A1 (enExample) |
| SG (2) | SG11201701712WA (enExample) |
| WO (1) | WO2016049000A2 (enExample) |
| ZA (1) | ZA201701663B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6694877B2 (ja) | 2014-09-23 | 2020-05-20 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 抗ｉｌ−２５抗体およびその使用 |
| WO2017189805A1 (en) | 2016-04-27 | 2017-11-02 | Abbvie Inc. | Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies |
| US11285191B2 (en) | 2016-07-26 | 2022-03-29 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Immunostimulatory compositions and uses therefor |
| CN107213463A (zh) * | 2017-05-24 | 2017-09-29 | 清华大学 | 白介素25在银屑病的发育中的作用 |
| DE102017215154A1 (de) | 2017-08-30 | 2019-02-28 | Markus Bläss | Zusammensetzung zur topischen Behandlung von nicht-Mikroorganismus-verursachten entzündlichen Haut- und Schleimhauterkrankungen |
| EP3883965A4 (en) * | 2018-11-19 | 2022-10-12 | Suzhou Kanova Biopharmaceutical Co., Ltd. | ANTI-IL-25 ANTIBODIES AND THEIR USE |
| AU2020407124A1 (en) | 2019-12-20 | 2022-07-21 | Momenta Pharmaceuticals, Inc. | Antibodies against integrin alpha 11 beta 1 |
| KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
| US11365239B2 (en) | 2020-03-20 | 2022-06-21 | Tsb Therapeutics (Beijing) Co., Ltd. | Anti-SARS-COV-2 antibodies and uses thereof |
| WO2022150660A1 (en) * | 2021-01-08 | 2022-07-14 | 10X Genomics, Inc. | Antigen-binding polypeptides specific for coronaviruses and uses thereof |
| US20240400671A1 (en) * | 2021-10-05 | 2024-12-05 | Richard A. Shimkets | Monoconal antibodies to il-25 and uses thereof |
| KR20240161653A (ko) * | 2022-02-24 | 2024-11-12 | 시노맙 바이오사이언스 리미티드 | 알라르민에 대한 이중 특이적 결합 단백질 및 이의 용도 |
| CN119451698A (zh) * | 2023-03-31 | 2025-02-14 | 新石生物制药有限公司 | 抗il-25抗体及其使用方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308236D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Dna vectors |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| US7060802B1 (en) * | 2000-09-18 | 2006-06-13 | The Trustees Of Columbia University In The City Of New York | Tumor-associated marker |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| CA2652976C (en) | 2006-06-02 | 2015-08-11 | Regeneron Pharmaceuticals, Inc. | High affinity antibodies to human il-6 receptor |
| GB0707505D0 (en) * | 2007-04-18 | 2007-05-30 | Medical Res Council | Antibodies against il-25 |
| GB0817891D0 (en) | 2008-09-30 | 2008-11-05 | Medical Res Council | Antibodies against il-25 |
| SG184195A1 (en) * | 2010-03-30 | 2012-11-29 | Janssen Biotech Inc | Humanized il-25 antibodies |
| WO2012097126A2 (en) * | 2011-01-13 | 2012-07-19 | The University Of Maryland, Baltimore | Il-25 treatment of obesity and metabolic disorders |
| DK2858670T3 (en) * | 2012-06-12 | 2018-10-22 | Orega Biotech | Antagonists of IL-17 isoforms and their applications |
| JP6694877B2 (ja) | 2014-09-23 | 2020-05-20 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 抗ｉｌ−２５抗体およびその使用 |
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2015
- 2015-09-22 JP JP2017515768A patent/JP6694877B2/ja active Active
- 2015-09-22 SG SG11201701712WA patent/SG11201701712WA/en unknown
- 2015-09-22 US US14/861,320 patent/US9840557B2/en active Active
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- 2015-09-22 CN CN201580063385.9A patent/CN107207589B/zh active Active
- 2015-09-22 EP EP15771489.0A patent/EP3197914B1/en active Active
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