CN111065651A - Il-5抗体、其抗原结合片段及医药用途 - Google Patents
Il-5抗体、其抗原结合片段及医药用途 Download PDFInfo
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Abstract
IL‑5抗体、其抗原结合片段及医药用途。包含IL‑5抗体CDR区的鼠源抗体、嵌合抗体、人源化抗体，以及包含IL‑5抗体及其抗原结合片段的药物组合物，以及其作为药物的用途。
Description
PCT国内申请，说明书已公开。
Claims (21)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710906068 | 2017-09-29 | ||
| CN201710906068X | 2017-09-29 | ||
| PCT/CN2018/108240 WO2019062831A1 (zh) | 2017-09-29 | 2018-09-28 | Il-5抗体、其抗原结合片段及医药用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111065651A true CN111065651A (zh) | 2020-04-24 |
| CN111065651B CN111065651B (zh) | 2023-07-14 |
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|---|---|---|---|
| CN201880058448.5A Active CN111065651B (zh) | 2017-09-29 | 2018-09-28 | Il-5抗体、其抗原结合片段及医药用途 |
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| Country | Link |
|---|---|
| US (2) | US11365247B2 (zh) |
| EP (1) | EP3689906A4 (zh) |
| JP (1) | JP7307720B2 (zh) |
| KR (1) | KR20200059239A (zh) |
| CN (1) | CN111065651B (zh) |
| AU (1) | AU2018340557A1 (zh) |
| BR (1) | BR112020005766A2 (zh) |
| CA (1) | CA3076941A1 (zh) |
| MX (1) | MX2020003034A (zh) |
| TW (1) | TWI801425B (zh) |
| WO (1) | WO2019062831A1 (zh) |
| ZA (1) | ZA202001807B (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020200099A1 (zh) * | 2019-03-29 | 2020-10-08 | 江苏恒瑞医药股份有限公司 | 包含抗il-5抗体的药物组合物及其用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175263A (zh) * | 1994-12-23 | 1998-03-04 | 史密丝克莱恩比彻姆公司 | 用于治疗il－5介导的疾病的重组il－5拮抗剂 |
| CN101883862A (zh) * | 2007-12-03 | 2010-11-10 | 爱德芳世株式会社 | 抗体制备方法 |
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| AU683836B2 (en) | 1992-02-06 | 1997-11-27 | Schering Corporation | Design, cloning and expression of humanized monoclonal antibodies against human interleukin-5 |
| GB9412230D0 (en) | 1994-06-17 | 1994-08-10 | Celltech Ltd | Interleukin-5 specific recombiant antibodies |
| US7399837B2 (en) | 1995-12-22 | 2008-07-15 | Smithkline Beecham Corporation | Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders |
| US5683892A (en) * | 1994-12-23 | 1997-11-04 | Smithkline Beecham Corporation | DNA encoding recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders |
| MXPA04009418A (es) | 2002-03-29 | 2005-06-08 | Schering Corp | Anticuerpos monoclonales humanos par interleucina-5, y metodos y composiciones que comprenden los mismos. |
| ATE541585T1 (de) | 2004-10-28 | 2012-02-15 | Kyowa Hakko Kirin Co Ltd | Antikörper gegen il-5-rezeptor zur verwendung in der behandlung von endometriose. |
| EP2222709B1 (en) * | 2007-11-30 | 2016-11-23 | Glaxo Group Limited | Antigen-binding constructs |
| US9505826B2 (en) | 2010-12-22 | 2016-11-29 | Teva Pharmaceuticals Australia Pty Ltd | Modified antibody with improved half-life |
| EP2710370A4 (en) | 2011-05-18 | 2015-01-07 | Medimmune Llc | METHODS OF DIAGNOSING AND TREATING PULMONARY DISEASES OR DISORDERS |
| CN114702594A (zh) | 2013-12-20 | 2022-07-05 | 豪夫迈·罗氏有限公司 | 双重特异性抗体 |
| ES2811124T3 (es) | 2014-09-08 | 2021-03-10 | Cephalon Inc | Uso de reslizumab para tratar el asma eosinofílica moderada a grave |
| CN116327921A (zh) | 2015-08-24 | 2023-06-27 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 生物医药组合物 |
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2018
- 2018-09-28 EP EP18860941.6A patent/EP3689906A4/en active Pending
- 2018-09-28 US US16/651,639 patent/US11365247B2/en active Active
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- 2018-09-28 WO PCT/CN2018/108240 patent/WO2019062831A1/zh unknown
- 2018-09-28 BR BR112020005766-5A patent/BR112020005766A2/pt unknown
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175263A (zh) * | 1994-12-23 | 1998-03-04 | 史密丝克莱恩比彻姆公司 | 用于治疗il－5介导的疾病的重组il－5拮抗剂 |
| CN101883862A (zh) * | 2007-12-03 | 2010-11-10 | 爱德芳世株式会社 | 抗体制备方法 |
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| US20200262909A1 (en) | 2020-08-20 |
| JP2021502801A (ja) | 2021-02-04 |
| US20220356239A1 (en) | 2022-11-10 |
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| MX2020003034A (es) | 2020-07-22 |
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| CN111065651B (zh) | 2023-07-14 |
| AU2018340557A1 (en) | 2020-04-09 |
| TWI801425B (zh) | 2023-05-11 |
| EP3689906A1 (en) | 2020-08-05 |
| ZA202001807B (en) | 2022-09-28 |
| WO2019062831A1 (zh) | 2019-04-04 |
| RU2020112984A (ru) | 2021-10-29 |
| CA3076941A1 (en) | 2019-04-04 |
| RU2020112984A3 (zh) | 2021-11-25 |
| BR112020005766A2 (pt) | 2020-10-13 |
| KR20200059239A (ko) | 2020-05-28 |
| US11365247B2 (en) | 2022-06-21 |
| JP7307720B2 (ja) | 2023-07-12 |
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