JP2017530193A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017530193A5 JP2017530193A5 JP2017535616A JP2017535616A JP2017530193A5 JP 2017530193 A5 JP2017530193 A5 JP 2017530193A5 JP 2017535616 A JP2017535616 A JP 2017535616A JP 2017535616 A JP2017535616 A JP 2017535616A JP 2017530193 A5 JP2017530193 A5 JP 2017530193A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- heterocycloalkyl
- aryl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RXYPXQSKLGGKOL-UHFFFAOYSA-N CN1CCN(C)CC1 Chemical compound CN1CCN(C)CC1 RXYPXQSKLGGKOL-UHFFFAOYSA-N 0.000 description 2
- TZYFCEGYHDNOFE-UHFFFAOYSA-N CC(CC1N(C)CCCC1)[n]1nncc1 Chemical compound CC(CC1N(C)CCCC1)[n]1nncc1 TZYFCEGYHDNOFE-UHFFFAOYSA-N 0.000 description 1
- PAMIQIKDUOTOBW-UHFFFAOYSA-N CN1CCCCC1 Chemical compound CN1CCCCC1 PAMIQIKDUOTOBW-UHFFFAOYSA-N 0.000 description 1
- JWAWEQBUZOGIBZ-UHFFFAOYSA-N C[n]1nncc1 Chemical compound C[n]1nncc1 JWAWEQBUZOGIBZ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462053389P | 2014-09-22 | 2014-09-22 | |
| US62/053,389 | 2014-09-22 | ||
| PCT/US2015/051143 WO2016048861A2 (en) | 2014-09-22 | 2015-09-21 | Heterocyclic compounds and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530193A JP2017530193A (ja) | 2017-10-12 |
| JP2017530193A5 true JP2017530193A5 (enExample) | 2018-11-01 |
| JP6615207B2 JP6615207B2 (ja) | 2019-12-04 |
Family
ID=55525127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017535616A Active JP6615207B2 (ja) | 2014-09-22 | 2015-09-21 | 複素環式化合物及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9862703B2 (enExample) |
| EP (1) | EP3197885B1 (enExample) |
| JP (1) | JP6615207B2 (enExample) |
| KR (1) | KR102509431B1 (enExample) |
| CN (1) | CN107207465B (enExample) |
| AU (1) | AU2015321654B2 (enExample) |
| BR (1) | BR112017005713B1 (enExample) |
| CA (1) | CA2962329C (enExample) |
| ES (1) | ES2849998T3 (enExample) |
| RU (1) | RU2704008C2 (enExample) |
| TW (1) | TWI598348B (enExample) |
| WO (1) | WO2016048861A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3047146C (en) * | 2017-01-10 | 2021-08-31 | Kak-Shan Shia | Heterocyclic compounds and use thereof |
| KR20240151869A (ko) * | 2017-09-08 | 2024-10-18 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | Enpp1 저해제 및 암의 치료용의 이의 용도 |
| WO2020060268A1 (ko) | 2018-09-20 | 2020-03-26 | 한미약품 주식회사 | 상피세포 성장인자 수용체 돌연변이 저해 효과를 갖는 신규 융합 피리미딘 골격 설폰아마이드 유도체 |
| US20220289775A1 (en) * | 2019-02-01 | 2022-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | ENPP1 Inhibitors and Methods of Modulating Immune Response |
| CN111138417B (zh) * | 2019-12-18 | 2021-03-23 | 浙江工业大学 | 一种三氮唑修饰的5-氟-2,4-嘧啶二胺类化合物及其应用 |
| CA3228210A1 (en) * | 2021-08-02 | 2023-02-09 | National Health Research Institutes | Pyrimidine compounds and use thereof |
| IL320644A (en) * | 2022-11-07 | 2025-07-01 | Univ Kyoto | Quinazoline derivatives |
| TW202435887A (zh) | 2023-03-01 | 2024-09-16 | 瑞士商諾華公司 | 用於治療疾病或障礙的氫喹唑啉衍生物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4936700A (enExample) * | 1972-08-16 | 1974-04-05 | ||
| PT633886E (pt) * | 1992-04-03 | 2001-03-30 | Upjohn Co | Aminas biciclicas-heterociclicas farmaceuticamente activas |
| US6156758A (en) * | 1999-09-08 | 2000-12-05 | Isis Pharmaceuticals, Inc. | Antibacterial quinazoline compounds |
| EP2043651A2 (en) | 2006-07-05 | 2009-04-08 | Exelixis, Inc. | Methods of using igf1r and abl kinase modulators |
| BRPI0909375A2 (pt) * | 2008-03-28 | 2015-08-04 | Altiris Therapeutics | Moduladores de receptores de quimiocinas |
| EP2284160B1 (en) * | 2008-03-31 | 2013-05-15 | Zenyaku Kogyo Kabushikikaisha | Pyrimidine derivative having cell-protecting activity and use thereof |
| EP2268635B1 (en) | 2008-04-21 | 2015-06-10 | Taigen Biotechnology Co., Ltd. | Heterocyclic compounds |
| WO2010046780A2 (en) | 2008-10-22 | 2010-04-29 | Institut Pasteur Korea | Anti viral compounds |
| GB201015411D0 (en) | 2010-09-15 | 2010-10-27 | Univ Leuven Kath | Anti-cancer activity of novel bicyclic heterocycles |
| AU2012313888B2 (en) | 2011-09-27 | 2016-03-31 | Novartis Ag | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH |
| EP2836240B1 (en) | 2012-04-10 | 2019-03-13 | Georgia State University Research Foundation, Inc. | Compositions and methods for treating otitis media and other conditions with inhibitors of cyld |
| EA035327B1 (ru) | 2012-10-10 | 2020-05-28 | Янссен Сайенсиз Айрлэнд Юси | Производные пирроло[3,2-d]пиримидина для лечения вирусных инфекций и других заболеваний |
| US20150259649A1 (en) * | 2012-11-08 | 2015-09-17 | Emory University | Cellular compositions used to restore stem cell or progenitor cell function and methods related thereto |
-
2015
- 2015-09-21 BR BR112017005713-1A patent/BR112017005713B1/pt active IP Right Grant
- 2015-09-21 CN CN201580050829.5A patent/CN107207465B/zh active Active
- 2015-09-21 ES ES15844487T patent/ES2849998T3/es active Active
- 2015-09-21 JP JP2017535616A patent/JP6615207B2/ja active Active
- 2015-09-21 AU AU2015321654A patent/AU2015321654B2/en active Active
- 2015-09-21 US US14/860,033 patent/US9862703B2/en active Active
- 2015-09-21 EP EP15844487.7A patent/EP3197885B1/en active Active
- 2015-09-21 RU RU2017109355A patent/RU2704008C2/ru active
- 2015-09-21 KR KR1020177010762A patent/KR102509431B1/ko active Active
- 2015-09-21 CA CA2962329A patent/CA2962329C/en active Active
- 2015-09-21 WO PCT/US2015/051143 patent/WO2016048861A2/en not_active Ceased
- 2015-09-22 TW TW104131241A patent/TWI598348B/zh active
-
2017
- 2017-09-22 US US15/712,978 patent/US9926298B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2017109355A (ru) | Гетероциклические соединения и их применение | |
| JP2017511357A5 (enExample) | ||
| PE20141700A1 (es) | Compuestos de 2-(2,4,5-anilino sustituido) pirimidina | |
| PE20171341A1 (es) | Compuestos de pirazina para el tratamiento de enfermedades infecciosas | |
| JP2021512150A5 (enExample) | ||
| CY1118909T1 (el) | Αμιδια οξαλικου οξεος ως αναστολεις νεπριλυσινης, φαρμακευτικη συνθεση αυτων και παρασκευη αυτων | |
| JP2016518328A5 (enExample) | ||
| JP2015522650A5 (enExample) | ||
| JP2016516043A5 (enExample) | ||
| JP2016053042A5 (enExample) | ||
| PE20190395A1 (es) | Pirimidin-2-ilamino-1h-pirazoles como inhibidores de lrrk2 para el uso en el tratamiento de trastornos neurodegenerativos | |
| AR059338A1 (es) | N-fenilbenzotriazolilo como inhibidores de c-kit | |
| PE20171177A1 (es) | Compuestos aminopirimidinilo inhibidores de jak | |
| JP2014506599A5 (enExample) | ||
| JP2017509586A5 (enExample) | ||
| JP2016540803A5 (enExample) | ||
| RU2016135922A (ru) | Терапевтические соединения и композиции | |
| AR064726A1 (es) | Inhibidores de rho quinasa | |
| JP2015534574A5 (enExample) | ||
| AR081587A1 (es) | DERIVADOS DE 5,6-DIHIDRO-2H-[1,4]OXAZIN-3-IL-AMINA UTILES COMO INHIBIDORES DE LA b-SECRETASA (BACE) | |
| JP2020500869A5 (enExample) | ||
| PE20141598A1 (es) | Derivados de dihidro-benzo-oxazina y dihidro-pirido-oxazina | |
| JP2019529419A5 (enExample) | ||
| AR073551A1 (es) | Pirimidinas macrociclicas como inhibidores de proteina cinasa | |
| PE20080856A1 (es) | Inhibidores de metaloproteasas de matriz |