JP2017529093A - リコンビナーゼ変異体 - Google Patents

リコンビナーゼ変異体 Download PDF

Info

Publication number
JP2017529093A
JP2017529093A JP2017516936A JP2017516936A JP2017529093A JP 2017529093 A JP2017529093 A JP 2017529093A JP 2017516936 A JP2017516936 A JP 2017516936A JP 2017516936 A JP2017516936 A JP 2017516936A JP 2017529093 A JP2017529093 A JP 2017529093A
Authority
JP
Japan
Prior art keywords
uvsx
phage
mutation
nucleic acid
recombinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017516936A
Other languages
English (en)
Japanese (ja)
Inventor
エリン ボマティ，
エリン ボマティ，
マシュー ウィリアム ケリンガー，
マシュー ウィリアム ケリンガー，
ジョナサン マーク ボーテル，
ジョナサン マーク ボーテル，
Original Assignee
イルミナ ケンブリッジ リミテッド
イルミナ ケンブリッジ リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イルミナ ケンブリッジ リミテッド, イルミナ ケンブリッジ リミテッド filed Critical イルミナ ケンブリッジ リミテッド
Publication of JP2017529093A publication Critical patent/JP2017529093A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/501—Ligase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
    • C12Y306/01008—ATP diphosphatase (3.6.1.8)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2017516936A 2014-09-29 2015-09-29 リコンビナーゼ変異体 Pending JP2017529093A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462057056P 2014-09-29 2014-09-29
US62/057,056 2014-09-29
PCT/US2015/053012 WO2016054088A1 (en) 2014-09-29 2015-09-29 Recombinase mutants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019143116A Division JP6879519B2 (ja) 2014-09-29 2019-08-02 リコンビナーゼ変異体

Publications (1)

Publication Number Publication Date
JP2017529093A true JP2017529093A (ja) 2017-10-05

Family

ID=54293382

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017516936A Pending JP2017529093A (ja) 2014-09-29 2015-09-29 リコンビナーゼ変異体
JP2019143116A Active JP6879519B2 (ja) 2014-09-29 2019-08-02 リコンビナーゼ変異体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019143116A Active JP6879519B2 (ja) 2014-09-29 2019-08-02 リコンビナーゼ変異体

Country Status (18)

Country Link
US (2) US9982244B2 (enExample)
EP (1) EP3201222B1 (enExample)
JP (2) JP2017529093A (enExample)
KR (3) KR20170065028A (enExample)
CN (1) CN107208075B (enExample)
AU (1) AU2015323936B2 (enExample)
BR (1) BR112017006542B1 (enExample)
CA (1) CA2962941C (enExample)
DK (1) DK3201222T3 (enExample)
ES (1) ES2729302T3 (enExample)
IL (1) IL251422B (enExample)
MX (1) MX385063B (enExample)
MY (1) MY182395A (enExample)
NZ (1) NZ730593A (enExample)
RU (1) RU2721920C2 (enExample)
SG (1) SG11201702493WA (enExample)
WO (1) WO2016054088A1 (enExample)
ZA (1) ZA201702248B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509716A (ja) * 2016-03-28 2019-04-11 イラミーナ インコーポレーテッド リコンビナーゼ変異体

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017529093A (ja) * 2014-09-29 2017-10-05 イルミナ ケンブリッジ リミテッド リコンビナーゼ変異体
JP7048609B2 (ja) * 2016-12-09 2022-04-05 ボリアル ジェノミクス， インコーポレイテッド 連結型ライゲーション
GB201704754D0 (en) 2017-01-05 2017-05-10 Illumina Inc Kinetic exclusion amplification of nucleic acid libraries
CN108913700B (zh) * 2018-08-16 2021-04-09 深圳市艾伟迪生物科技有限公司 gp32单链结合蛋白的制备方法、表达基因、重组表达载体及应用
CN115975956A (zh) * 2022-02-23 2023-04-18 杨挥 一种重组酶突变体及包含该突变体的核酸等温扩增反应体系

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009535053A (ja) * 2006-05-04 2009-10-01 エーエスエム サイエンティフィック， インコーポレイテッド レコンビナーゼポリメラーゼ増幅
JP2014516512A (ja) * 2011-04-07 2014-07-17 アリーア サン ディエゴ， インコーポレイテッド リコンビナーゼポリメラーゼ増幅混合物のモニタリング
JP2019213545A (ja) * 2014-09-29 2019-12-19 イルミナ ケンブリッジ リミテッド リコンビナーゼ変異体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
DK1499738T3 (da) 2002-02-21 2008-11-17 Asm Scient Inc Recombinase-polymerease-amplifikation
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
US6897069B1 (en) 2004-06-08 2005-05-24 Ambion, Inc. System and method for electroporating a sample
EP2829615B1 (en) 2005-07-25 2018-05-09 Alere San Diego, Inc. Kit for multiplexing recombinase polymerase amplification
US7742463B2 (en) 2005-08-18 2010-06-22 Hong Kong Applied Science And Technology Research Institute Co., Ltd. Security gatekeeper for a packetized voice communication network
WO2010141940A1 (en) * 2009-06-05 2010-12-09 Alere San Diego, Inc. Recombinase polymerase amplification reagents and kits
CN103153960B (zh) 2010-09-21 2015-02-25 巴斯夫欧洲公司 制备取代的n-苯基羟胺的方法
US8895249B2 (en) 2012-06-15 2014-11-25 Illumina, Inc. Kinetic exclusion amplification of nucleic acid libraries

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009535053A (ja) * 2006-05-04 2009-10-01 エーエスエム サイエンティフィック， インコーポレイテッド レコンビナーゼポリメラーゼ増幅
JP2014516512A (ja) * 2011-04-07 2014-07-17 アリーア サン ディエゴ， インコーポレイテッド リコンビナーゼポリメラーゼ増幅混合物のモニタリング
JP2019213545A (ja) * 2014-09-29 2019-12-19 イルミナ ケンブリッジ リミテッド リコンビナーゼ変異体

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
CHEN, J. ET AL., NUCLEIC ACIDS RES., vol. 38, no. 14, JPN6020003528, 2010, pages 4889 - 4906, ISSN: 0004205693 *
CHI, P. ET AL., DNA REPAIR, vol. 5, JPN6018015200, 2006, pages 381 - 391, ISSN: 0003787423 *
FARB, J.N. AND MORRICAL, S.W., J. MOL. BIOL., vol. 385, JPN6018015202, 2009, pages 393 - 404, ISSN: 0004205694 *
GAJEWSKI, S. ET AL., J. MOL. BIOL., vol. 405, JPN6018015207, 2011, pages 65 - 76, ISSN: 0003787426 *
KIM, D. ET AL., PLOS ONE, vol. 8, no. 4, JPN6020003525, 2013, pages 60585 - 1, ISSN: 0004205690 *
MAHER, R.L. AND MORRICAL, S.W., PLOS ONE, vol. 8, no. 6, JPN6020003527, 2013, pages 66654 - 1, ISSN: 0004205691 *
SHAN, Q. ET AL., J. BIOL. CHEM., vol. 271, no. 10, JPN6018015197, 1996, pages 5712 - 5724, ISSN: 0003787422 *
SHARMA, D. ET AL., DNA REPAIR, vol. 12, JPN6018015186, 2013, pages 53 - 62, ISSN: 0003787421 *
ZHANG, J., J. MOL. EVOL., vol. 50, JPN6019051431, 2000, pages 56 - 68, ISSN: 0004205692 *
細胞生物学事典, vol. 初版, 第1刷, JPN6017010535, 2005, pages 417 - 418, ISSN: 0003787424 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509716A (ja) * 2016-03-28 2019-04-11 イラミーナ インコーポレーテッド リコンビナーゼ変異体

Also Published As

Publication number Publication date
AU2015323936A1 (en) 2017-04-20
SG11201702493WA (en) 2017-04-27
KR102126641B1 (ko) 2020-06-24
CA2962941C (en) 2022-06-14
KR20200026320A (ko) 2020-03-10
JP2019213545A (ja) 2019-12-19
IL251422A0 (en) 2017-05-29
BR112017006542B1 (pt) 2023-11-14
JP6879519B2 (ja) 2021-06-02
US10344269B2 (en) 2019-07-09
DK3201222T3 (da) 2019-06-24
NZ730593A (en) 2023-06-30
WO2016054088A1 (en) 2016-04-07
US20160090581A1 (en) 2016-03-31
CN107208075B (zh) 2021-08-24
US9982244B2 (en) 2018-05-29
IL251422B (en) 2020-10-29
EP3201222A1 (en) 2017-08-09
MY182395A (en) 2021-01-23
RU2017110582A3 (enExample) 2019-04-15
CN107208075A (zh) 2017-09-26
RU2721920C2 (ru) 2020-05-25
AU2015323936B2 (en) 2021-03-11
ZA201702248B (en) 2019-06-26
US20180258409A1 (en) 2018-09-13
MX2017004034A (es) 2017-11-17
KR20170065028A (ko) 2017-06-12
ES2729302T3 (es) 2019-10-31
BR112017006542A2 (pt) 2018-01-23
CA2962941A1 (en) 2016-04-07
MX385063B (es) 2025-03-14
EP3201222B1 (en) 2019-04-10
KR20190037364A (ko) 2019-04-05
RU2017110582A (ru) 2018-11-07

Similar Documents

Publication Publication Date Title
US11198854B2 (en) Modified polymerases for improved incorporation of nucleotide analogues
JP6879519B2 (ja) リコンビナーゼ変異体
US10287560B2 (en) Recombinase mutants
EP4399299A1 (en) Systems, compositions, and methods involving retrotransposons and functional fragments thereof
HK1235066B (en) Recombinase mutants
HK1235066A1 (en) Recombinase mutants
HK1261197B (en) Recombinase mutants
HK1261197A1 (en) Recombinase mutants
HK1235089A1 (en) Modified polymerases for improved incorporation of nucleotide analogues

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170526

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180508

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180803

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190205

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190507

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190705

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190802

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20190920

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20200204