JP2017528158A5 - - Google Patents
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- JP2017528158A5 JP2017528158A5 JP2017524110A JP2017524110A JP2017528158A5 JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5 JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- lentiviral vector
- vector
- antigen receptor
- chimeric antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156063A JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028889P | 2014-07-25 | 2014-07-25 | |
| US62/028,889 | 2014-07-25 | ||
| US201562155811P | 2015-05-01 | 2015-05-01 | |
| US62/155,811 | 2015-05-01 | ||
| EP15306036 | 2015-06-29 | ||
| EP15306036.3 | 2015-06-29 | ||
| PCT/EP2015/067090 WO2016012623A1 (en) | 2014-07-25 | 2015-07-24 | Lentiviral vectors for regulated expression of a chimeric antigen receptor molecule |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Division JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528158A JP2017528158A (ja) | 2017-09-28 |
| JP2017528158A5 true JP2017528158A5 (Direct) | 2018-08-30 |
| JP6940406B2 JP6940406B2 (ja) | 2021-09-29 |
Family
ID=53514131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524110A Expired - Fee Related JP6940406B2 (ja) | 2014-07-25 | 2015-07-24 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10752668B2 (Direct) |
| EP (2) | EP3511413B1 (Direct) |
| JP (3) | JP6940406B2 (Direct) |
| CN (2) | CN113846062B (Direct) |
| CA (1) | CA2956385A1 (Direct) |
| WO (1) | WO2016012623A1 (Direct) |
Families Citing this family (29)
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| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| MX395154B (es) * | 2015-10-22 | 2025-03-25 | Juno Therapeutics Gmbh | Métodos, kits, agentes y aparatos para transducción. |
| WO2017180587A2 (en) * | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| CN108276493B (zh) * | 2016-12-30 | 2023-11-14 | 南京传奇生物科技有限公司 | 一种嵌合抗原受体及其应用 |
| SG11201909931PA (en) | 2017-04-27 | 2019-11-28 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| EP3618870A4 (en) | 2017-05-01 | 2021-04-21 | The Trustees of The University of Pennsylvania | MONOCLONAL ANTIBODIES AGAINST ALPHA-SYNUCLEIN FIBRILLES |
| WO2019077165A1 (en) | 2017-10-20 | 2019-04-25 | Institut Curie | DAP10 / 12-BASED CHIMERIC ANTIGENIC RECEPTORS (CAR) ADAPTED FOR RUSH |
| WO2019077164A1 (en) | 2017-10-20 | 2019-04-25 | Institut Curie | CROCHET FUSION PROTEIN FOR REGULATING THE CELLULAR TRAFFIC OF A TARGET PROTEIN |
| US11760806B2 (en) | 2017-11-03 | 2023-09-19 | Sorrento Therapeutics, Inc. | CD-38 directed chimeric antigen receptor constructs |
| EP3740199B1 (en) | 2018-01-17 | 2024-08-14 | Ixaka France | Polymer-encapsulated viral vectors for genetic therapy |
| EP3549597A1 (en) * | 2018-04-06 | 2019-10-09 | Heinrich-Heine-Universität Düsseldorf | Synthetic signalling constructs and its use |
| EP3781176A4 (en) * | 2018-04-09 | 2022-05-25 | The Trustees of the University of Pennsylvania | METHODS AND COMPOSITIONS USING A VIRAL VECTOR FOR THE EXPRESSION OF A TRANSGENE AND AN EFFECTOR |
| US12215337B2 (en) * | 2018-04-12 | 2025-02-04 | Umoja Biopharma, Inc. | Viral vectors and packaging cell lines |
| IL280659B2 (en) | 2018-08-09 | 2024-11-01 | Juno Therapeutics Inc | Processes for generating engineered cells and compositions thereof |
| EP3874024A1 (en) | 2018-10-31 | 2021-09-08 | Juno Therapeutics GmbH | Methods for selection and stimulation of cells and apparatus for same |
| CN114258401B (zh) * | 2019-07-16 | 2025-08-12 | Inserm(法国国家健康医学研究院) | 对cd38具有特异性的抗体及其用途 |
| AU2020345943B2 (en) | 2019-09-10 | 2026-02-12 | Obsidian Therapeutics, Inc. | CA2-IL15 fusion proteins for tunable regulation |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| CA3170369A1 (en) | 2020-03-05 | 2022-04-14 | Michal Shahar | Methods and compositions for treating cancer with immune cells |
| US20230323394A1 (en) * | 2020-09-01 | 2023-10-12 | The Trustees Of The University Of Pennsylvania | Improved generation of lentiviral vectors for t cell transduction using cocal envelope |
| WO2022101482A1 (en) | 2020-11-13 | 2022-05-19 | Honing Biosciences | Means and methods for regulating intracellular trafficking of secretory or cell membrane-anchored proteins of interest |
| AU2022267891A1 (en) * | 2021-04-27 | 2023-11-09 | Novartis Ag | Viral vector production system |
| IT202100011576A1 (it) * | 2021-05-06 | 2022-11-06 | Univ Degli Studi Padova | Nuova sequenza promotore per terapia genica |
| JP2024544566A (ja) | 2021-11-15 | 2024-12-03 | セラベクティス | ヒトパピローマウイルス(hpv)抗原の発現の為のレンチウイルスベクター、並びにhpv誘発癌の処置におけるその実施 |
| CA3256704A1 (en) * | 2022-05-23 | 2023-11-30 | The Broad Institute, Inc. | METHODS AND COMPOSITIONS FOR CRISPR SCREENING OF IMMUNE CELLS |
| CA3263030A1 (en) | 2022-07-27 | 2024-02-01 | Institut Pasteur | Lentiviral vectors for the expression of human papillomavirus (HPV) antigens and their use in the treatment of HPV-induced cancers |
| US12484900B2 (en) | 2023-07-21 | 2025-12-02 | Cilag Gmbh International | Systems and subsystems for rolling a surgical instrument including articulation cables |
| EP4624494A1 (en) | 2024-03-29 | 2025-10-01 | Institut Curie | Her2 single domain antibody and uses thereof |
| WO2026020171A2 (en) | 2024-07-19 | 2026-01-22 | Aera Therapeutics, Inc. | Chimeric antigen receptor constructs |
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| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
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| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| EP0247091B1 (en) | 1985-11-01 | 1993-09-29 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| AU4308689A (en) | 1988-09-02 | 1990-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
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| DE69127627T2 (de) | 1990-08-29 | 1998-02-19 | Genpharm Int | Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| ES2330052T3 (es) | 1991-03-01 | 2009-12-03 | Dyax Corporation | Proteina quimerica que comprende micro-proteinas que tienen dos o mas puentes disulfuro y relaizaciones de las mismas. |
| ATE414768T1 (de) | 1991-04-10 | 2008-12-15 | Scripps Research Inst | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| DE4135543A1 (de) | 1991-10-28 | 1993-04-29 | Boehringer Mannheim Gmbh | Rekombinantes core-streptavidin |
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| EP1390057A4 (en) * | 2001-04-03 | 2005-10-12 | Curagen Corp | ANTIBODIES BINDING TO ANTIGENOUS POLYPEPTIDES, NUCLEIC ACIDS COATING ANTIGENS, AND METHODS OF USE |
| AU2002307625A1 (en) * | 2002-03-08 | 2003-09-22 | Cueros Industrializados Del Bajio | Method of incorporating heat-stable particles into leather |
| US20050032173A1 (en) * | 2003-08-05 | 2005-02-10 | Mauricio Rojas | Fusion proteins with a membrane translocating sequence and methods of using same to inhibit an immune response |
| US20130266551A1 (en) * | 2003-11-05 | 2013-10-10 | St. Jude Children's Research Hospital, Inc. | Chimeric receptors with 4-1bb stimulatory signaling domain |
| US7265205B2 (en) * | 2005-02-11 | 2007-09-04 | Uti Limited Partnership | Monomeric streptavidin muteins |
| WO2007109370A2 (en) * | 2006-03-22 | 2007-09-27 | Viral Logic Systems Technology Corp. | Methods for identifying polypeptide targets and uses thereof for treating immunological diseases |
| WO2008105968A1 (en) * | 2006-11-03 | 2008-09-04 | Smithkline Beecham Corporation | Novel seh inhibitors and their use |
| EP2147683A1 (en) | 2008-07-25 | 2010-01-27 | DKFZ Deutsches Krebsforschungszentrum | Construct and method for the internalization of cargo molecules into a cell |
| CA2765321A1 (en) * | 2009-06-11 | 2010-12-16 | Franck Perez | Methods and kits for regulating intracellular trafficking of a target protein |
| US9233125B2 (en) * | 2010-12-14 | 2016-01-12 | University Of Maryland, Baltimore | Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer |
| NZ713461A (en) * | 2011-04-15 | 2017-02-24 | Compugen Ltd | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| EA201491574A1 (ru) * | 2012-02-22 | 2014-12-30 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Применение car, основанных на icos, для усиления противоопухолевой активности и длительного сохранения car |
| SI2884999T2 (sl) * | 2012-08-20 | 2026-01-30 | Fred Hutchinson Cancer Center | Metoda in sestavki za celično imunoterapijo |
| CA2886684C (en) * | 2012-10-10 | 2023-09-19 | Sangamo Biosciences, Inc. | T cell modifying compounds and uses thereof |
| JP6942467B2 (ja) * | 2013-12-20 | 2021-10-06 | フレッド ハッチンソン キャンサー リサーチ センター | タグ化キメラエフェクター分子およびそのレセプター |
| IL295616A (en) * | 2015-07-31 | 2022-10-01 | Us Health | Adapted cells and treatment methods |
-
2015
- 2015-07-24 EP EP19159129.6A patent/EP3511413B1/en active Active
- 2015-07-24 US US15/327,517 patent/US10752668B2/en active Active
- 2015-07-24 CA CA2956385A patent/CA2956385A1/en active Pending
- 2015-07-24 WO PCT/EP2015/067090 patent/WO2016012623A1/en not_active Ceased
- 2015-07-24 CN CN202110939899.3A patent/CN113846062B/zh active Active
- 2015-07-24 CN CN201580051938.9A patent/CN107531800B/zh active Active
- 2015-07-24 EP EP15742027.4A patent/EP3172228B1/en active Active
- 2015-07-24 JP JP2017524110A patent/JP6940406B2/ja not_active Expired - Fee Related
-
2020
- 2020-07-17 US US16/931,986 patent/US20210009653A1/en not_active Abandoned
- 2020-09-17 JP JP2020156063A patent/JP7341110B2/ja active Active
-
2023
- 2023-05-10 JP JP2023078059A patent/JP2023113656A/ja not_active Withdrawn
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