JP2017528120A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017528120A5 JP2017528120A5 JP2017501219A JP2017501219A JP2017528120A5 JP 2017528120 A5 JP2017528120 A5 JP 2017528120A5 JP 2017501219 A JP2017501219 A JP 2017501219A JP 2017501219 A JP2017501219 A JP 2017501219A JP 2017528120 A5 JP2017528120 A5 JP 2017528120A5
- Authority
- JP
- Japan
- Prior art keywords
- chemoreceptor
- test compound
- biological sample
- level
- genes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14182350 | 2014-08-26 | ||
| EP14182350.0 | 2014-08-26 | ||
| PCT/EP2015/069454 WO2016030378A1 (en) | 2014-08-26 | 2015-08-25 | Methods for identifying a receptor for a ligand and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017528120A JP2017528120A (ja) | 2017-09-28 |
| JP2017528120A5 true JP2017528120A5 (https=) | 2018-08-16 |
Family
ID=51392198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017501219A Pending JP2017528120A (ja) | 2014-08-26 | 2015-08-25 | リガンドに対する受容体を同定するための方法およびその使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10473645B2 (https=) |
| EP (1) | EP3194978B1 (https=) |
| JP (1) | JP2017528120A (https=) |
| WO (1) | WO2016030378A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109071626A (zh) | 2016-02-24 | 2018-12-21 | 阿罗姆斯公司 | 用于检测气味、香味和味道的生物传感器 |
| WO2017173055A1 (en) | 2016-03-30 | 2017-10-05 | The Johns Hopkins University | Olfr90 specificity and methods of detection |
| CA3034419C (en) * | 2016-09-30 | 2023-01-03 | Mars, Incorporated | Screening methods using olfactory receptors and novel compounds identified using the same |
| US11029308B2 (en) | 2016-10-27 | 2021-06-08 | Duke University | Methods for vapor detection and discrimination with mammalian odorant receptors expressed in heterologous cells |
| EP3336544B1 (en) * | 2016-12-14 | 2019-11-27 | Takasago International Corporation | Method for identifying malodour counteractants |
| JP2020510417A (ja) * | 2017-02-17 | 2020-04-09 | コニク インコーポレイテッド | 検出のためのシステム |
| EP3609521A4 (en) * | 2017-04-14 | 2021-06-16 | University of Massachusetts | TARGETING OF CELL TROPISM RECEPTORS TO INHIBIT INFECTION BY THE CYTOMEGALOVIRUS |
| US10209239B1 (en) * | 2017-08-16 | 2019-02-19 | Aromyx Corporation | Method of making an aromagraph comprising ectopic olfactory receptors |
| KR102012837B1 (ko) * | 2017-09-18 | 2019-08-21 | 중앙대학교 산학협력단 | G9a 및 LSD1에 의한 후각 수용체 발현 조절을 이용한 백혈병 치료제 스크리닝 방법 |
| WO2019101812A2 (en) * | 2017-11-22 | 2019-05-31 | Firmenich Sa | Method of identifying laundry malodor, moldy malodor and/or sweat malodor modulating compounds |
| SG11202001226PA (en) * | 2017-12-21 | 2020-03-30 | Firmenich & Cie | Method for identifying positive allosteric modulators for odorant receptors |
| US12163950B2 (en) | 2018-06-26 | 2024-12-10 | Duke University | Synthetic odorant receptors |
| WO2020033753A1 (en) | 2018-08-10 | 2020-02-13 | Koniku Inc. | A stacked integrated platform architecture |
| KR20200052189A (ko) | 2018-11-06 | 2020-05-14 | 한국식품연구원 | Spr 센서를 이용한 세포막단백질-리간드 상호작용의 확인 방법 |
| US12165743B2 (en) | 2018-11-09 | 2024-12-10 | The Broad Institute, Inc. | Compressed sensing for screening and tissue imaging |
| JP7658911B2 (ja) * | 2019-11-01 | 2025-04-08 | 高砂香料工業株式会社 | 悪臭抑制素材のスクリーニング方法 |
| CN111939260B (zh) * | 2019-12-11 | 2021-12-14 | 山东大学 | 嗅觉受体or12d3作为糖尿病防治靶点的应用 |
| JP2022187352A (ja) * | 2021-06-07 | 2022-12-19 | エステー株式会社 | 嗅覚受容体の阻害剤、消臭剤、消臭方法 |
| JP7776818B2 (ja) * | 2022-02-10 | 2025-11-27 | エステー株式会社 | アルデヒド臭の抑制剤の探索方法 |
| CN121729502A (zh) * | 2023-08-31 | 2026-03-24 | 高砂香料工业株式会社 | 恶臭抑制材料的筛选方法 |
| CN117487815B (zh) * | 2023-10-16 | 2025-03-18 | 中国农业科学院深圳农业基因组研究所(岭南现代农业科学与技术广东省实验室深圳分中心) | 气味受体基因OR49b识别苯并噻唑及其在橘小实蝇防控方面的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000035274A1 (en) * | 1998-12-17 | 2000-06-22 | The Johns Hopkins University School Of Medicine | Olfactory receptor expression libraries and methods of making and using them |
| CA2401406A1 (en) * | 2000-03-13 | 2001-09-20 | Senomyx, Inc. | Human olfactory receptors and genes encoding same |
| AU2002326834A1 (en) * | 2001-09-04 | 2003-03-18 | Sentigen Corp. | Anopheles gambiae odorant receptors and genes |
| EP1391508A1 (en) * | 2002-08-09 | 2004-02-25 | F. Hoffmann-La Roche Ag | Transgenic nematode expressing mammalian GPCRS used for screening assay |
-
2015
- 2015-08-25 WO PCT/EP2015/069454 patent/WO2016030378A1/en not_active Ceased
- 2015-08-25 EP EP15754209.3A patent/EP3194978B1/en active Active
- 2015-08-25 JP JP2017501219A patent/JP2017528120A/ja active Pending
- 2015-08-25 US US15/506,266 patent/US10473645B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017528120A5 (https=) | ||
| Zhang et al. | Mechanically activated piezo channels mediate touch and suppress acute mechanical pain response in mice | |
| Morris et al. | Single‐cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin‐driven circadian network | |
| Yamada et al. | Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain | |
| Acharya et al. | Efficient inducible Cre‐mediated recombination in Tcf21cell lineages in the heart and kidney | |
| Bozdagi et al. | Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice | |
| Kucherenko et al. | Steroid-induced microRNA let-7 acts as a spatio-temporal code for neuronal cell fate in the developing Drosophila brain | |
| Willett et al. | Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth | |
| HRP20190227T1 (hr) | Životinje koje nisu ljudi, koje imaju humanizirani gen za protein za reguliranje signala | |
| HRP20210662T1 (hr) | Neljudske životinje koje imaju humanizirani gen za diferencijacijski biljeg 47 | |
| FI3808775T3 (fi) | Ei-ihmiseläimiä, joilla on humanisoitu erilaistumisklusteri 274 -geeni | |
| Rubin et al. | Experience and the ever‐changing brain: what the transcriptome can reveal | |
| RU2020103811A (ru) | Гуманизированные животные по с5 и с3 | |
| HRP20211455T1 (hr) | Životinje s humaniziranim il-4 i il-4r alfa | |
| RU2016102922A (ru) | Способы идентификации, изоляции и применения рецепторов пахучих веществ и ароматов | |
| Abellán et al. | The olfactory amygdala in amniotes: An evo‐devo approach | |
| JP2017514496A5 (https=) | ||
| Bellini et al. | Neuronal glutamate transporters control dopaminergic signaling and compulsive behaviors | |
| RU2009129185A (ru) | Способы и мишени для идентификации соединений для регуляции риновирусной инфекции | |
| Mar et al. | Genetic marking and characterization of Tac2-expressing neurons in the central and peripheral nervous system | |
| Petersen et al. | A transcriptional program promotes remodeling of GABAergic synapses in Caenorhabditis elegans | |
| Tivodar et al. | Rac-GTPases regulate microtubule stability and axon growth of cortical GABAergic interneurons | |
| HRP20200899T1 (hr) | Neljudske životinje koje imaju humanizirane fc-gamma receptore | |
| Jung et al. | Neuromodulation of olfactory sensitivity in the peripheral olfactory organs of the American cockroach, Periplaneta americana | |
| Kim et al. | Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms |