JP2017526627A5 - - Google Patents

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Publication number
JP2017526627A5
JP2017526627A5 JP2016574989A JP2016574989A JP2017526627A5 JP 2017526627 A5 JP2017526627 A5 JP 2017526627A5 JP 2016574989 A JP2016574989 A JP 2016574989A JP 2016574989 A JP2016574989 A JP 2016574989A JP 2017526627 A5 JP2017526627 A5 JP 2017526627A5
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JP
Japan
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sequence number
polypeptide
seq
fragment
sequence
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JP2016574989A
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Japanese (ja)
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JP2017526627A (ja
JP6818349B2 (ja
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Priority claimed from PCT/US2015/037962 external-priority patent/WO2015200783A2/en
Publication of JP2017526627A publication Critical patent/JP2017526627A/ja
Publication of JP2017526627A5 publication Critical patent/JP2017526627A5/ja
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Publication of JP6818349B2 publication Critical patent/JP6818349B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016574989A 2014-06-26 2015-06-26 アシネトバクター溶解素 Expired - Fee Related JP6818349B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462017618P 2014-06-26 2014-06-26
US62/017,618 2014-06-26
PCT/US2015/037962 WO2015200783A2 (en) 2014-06-26 2015-06-26 Acinetobacter lysins

Publications (3)

Publication Number Publication Date
JP2017526627A JP2017526627A (ja) 2017-09-14
JP2017526627A5 true JP2017526627A5 (https=) 2018-08-09
JP6818349B2 JP6818349B2 (ja) 2021-01-20

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ID=54938953

Family Applications (1)

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JP2016574989A Expired - Fee Related JP6818349B2 (ja) 2014-06-26 2015-06-26 アシネトバクター溶解素

Country Status (14)

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US (2) US10590403B2 (https=)
EP (1) EP3164146B1 (https=)
JP (1) JP6818349B2 (https=)
KR (1) KR102441211B1 (https=)
CN (1) CN106659748B (https=)
AU (1) AU2015279705B2 (https=)
BR (1) BR112016030580B1 (https=)
CA (1) CA2953446A1 (https=)
ES (1) ES2767294T3 (https=)
GB (1) GB2543453A (https=)
IL (1) IL249636A0 (https=)
NZ (1) NZ728429A (https=)
RU (1) RU2725809C2 (https=)
WO (1) WO2015200783A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015279705B2 (en) * 2014-06-26 2021-04-01 The Rockefeller University Acinetobacter lysins
BR112020011433A2 (pt) 2017-12-12 2020-12-01 Contrafect Corporation identificação de lisinas e seus derivados com atividade bacteriana contra pseudomonas aeruginosa
CN112368376A (zh) 2018-03-29 2021-02-12 康特拉费克特公司 溶素-抗微生物肽(amp)多肽构建体、溶素、其分离的编码多核苷酸及其用途
US10988520B2 (en) 2018-03-29 2021-04-27 Contrafect Corporation Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
WO2020046747A1 (en) * 2018-08-23 2020-03-05 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
EP3946609A4 (en) * 2019-04-05 2023-05-03 Contrafect Corporation LYSINE AND ITS DERIVATIVES WITH BACTERICIDAL ACTIVITY AGAINST PSEUDOMONAS AERUGINOSA IN THE PRESENCE OF HUMAN SERUM
CN111909917B (zh) * 2019-05-10 2022-10-14 中国科学院微生物研究所 一种内溶素Lysmeta1及其编码基因与应用
MX2022011291A (es) 2020-03-11 2022-12-08 Telum Therapeutics S L Nueva lisina recombinante y su uso en el tratamiento de infecciones por bacterias gramnegativas.
KR102604590B1 (ko) * 2020-09-28 2023-11-23 경북대학교 산학협력단 아시네토박터 바우마니에 대한 사멸능을 가지는 박테리오파지 및 이를 포함하는 조성물
KR102419028B1 (ko) * 2021-01-06 2022-07-08 주식회사 리신바이오 박테리오파지 유래 신규 재조합 엔도라이신 및 이의 용도
WO2022236088A1 (en) * 2021-05-06 2022-11-10 Bioharmony Therapeutics Inc. Lysin polypeptide compositions and methods of use
KR102776341B1 (ko) * 2023-11-24 2025-03-10 경북대학교 산학협력단 아시네토박터 바우마니에 대한 특이적 결합능을 갖는 재조합 단백질 및 이의 용도

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030113298A1 (en) * 1997-10-31 2003-06-19 Vincent Fischetti Use of bacterial phage associated lysing proteins for the prophylactic and therapeutic treatment of various illnesses
US20060292135A1 (en) * 1997-10-31 2006-12-28 Lawrence Loomis Use of bacterial phage-associated lysing proteins for preventing and treating bacterial infections in humans, animals and fowl
US6056954A (en) * 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US5997862A (en) * 1997-10-31 1999-12-07 New Horizons Diagnostics Corporation Therapeutic treatment of group A streptococcal infections
US6562958B1 (en) * 1998-06-09 2003-05-13 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Acinetobacter baumannii for diagnostics and therapeutics
US6133010A (en) 1999-07-08 2000-10-17 Biotec Asa Chlamysin B antibacterial protein, a protein gene for and an expression system for same
US20100233146A1 (en) * 2002-09-09 2010-09-16 Reactive Surfaces, Ltd. Coatings and Surface Treatments Having Active Enzymes and Peptides
US7604975B2 (en) * 2002-10-01 2009-10-20 The Rockefeller University Glycosylated LPXTGases and uses thereof
EP1651258B1 (en) * 2003-07-30 2014-03-19 Vaccine Research Institute of San Diego Hepatitis virus core proteins as vaccine platforms and methods of use thereof
US7320795B2 (en) * 2003-07-30 2008-01-22 Vaccine Research Institute Of San Diego Rodent hepatitis B virus core proteins as vaccine platforms and methods of use thereof
US7144712B2 (en) * 2003-07-30 2006-12-05 Vaccine Research Institute Of San Diego Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof
US20070077235A1 (en) * 2004-01-16 2007-04-05 Lawrence Loomis Composition and method of treating mastitis
AU2007272272B2 (en) 2006-07-10 2012-04-12 Pba3 Biomed Gmbh Antimicrobial peptides
US9999635B2 (en) * 2007-01-16 2018-06-19 Realm Therapeutics, Inc. Methods and compositions for treating inflammatory disorders
US20110262508A1 (en) * 2007-11-07 2011-10-27 Paul Michael Watt Antimicrobial compositions, formulations and uses thereof
EP2157100A1 (en) 2008-08-19 2010-02-24 Profos AG Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins
GB0815484D0 (en) * 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
CN102223876A (zh) * 2008-09-26 2011-10-19 纳米生物公司 纳米乳剂治疗性组合物及其使用方法
EP2371840B1 (en) 2008-11-28 2014-04-16 AnGes MG, Inc. Novel polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
KR101016918B1 (ko) 2009-01-08 2011-02-25 주식회사 인트론바이오테크놀로지 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질
DK2445515T3 (en) * 2009-06-26 2016-07-04 Univ Leuven Kath antimicrobial agents
SG178440A1 (en) 2009-08-24 2012-04-27 Univ Leuven Kath New endolysin obpgplys
US9005579B2 (en) * 2010-01-05 2015-04-14 Contrafect Corporation Methods and compositions for enhanced immunological therapy and targeting of gram-positive bacteria
EA037276B1 (ru) * 2010-04-27 2021-03-03 Лисандо Аг Способы устранения или уменьшения бактериальной биопленки
SG188566A1 (en) * 2010-09-17 2013-04-30 Tecnifar Ind Tecnica Farmaceutica S A Antibacterial phage, phage peptides and methods of use thereof
EP2468856A1 (en) 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimicrobial Agents
GB201103780D0 (en) * 2011-03-04 2011-04-20 Hansa Medical Ab Treatment for ige-mediated disease
CA2833409A1 (en) * 2011-04-21 2012-10-26 The Rockefeller University Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria
HUE047099T2 (hu) * 2011-10-08 2020-04-28 Next Science IP Holdings Pty Ltd Antimikrobiális kompozíciók és eljárások alkalmazásukra
KR20210121313A (ko) * 2012-05-09 2021-10-07 콘트라펙트 코포레이션 그람 양성 박테리아에 대한 박테리오파지 리신과 항생제의 병용물
KR20200023521A (ko) * 2012-05-09 2020-03-04 콘트라펙트 코포레이션 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료
KR101391332B1 (ko) * 2012-05-18 2014-05-07 연세대학교 산학협력단 카바페넴 제제에 내성을 보이는 아시네토박터 속의 균을 용균하는 박테리오파아지
EP2882756A4 (en) * 2012-08-08 2016-11-23 Avacyn Pharmaceuticals Inc INHIBITION OF ANTIMICROBIAL OBJECTIVES WITH REDUCED POTENTIAL FOR RESISTANCE
CN102940874B (zh) 2012-12-12 2013-12-18 中国科学院昆明动物研究所 小分子多肽cw14在制备山羊抗菌药物中的应用
WO2014124047A1 (en) * 2013-02-06 2014-08-14 Academia Sinica Antimicrobial peptides derived from hepatitis b virus core protein arginine-rich domain
AU2015279705B2 (en) * 2014-06-26 2021-04-01 The Rockefeller University Acinetobacter lysins
JP6863966B2 (ja) * 2015-08-25 2021-04-21 シャアメン ユニバーシティ 標的ポリペプチドを提示するためのポリペプチド担体及びその使用
AU2016324307B2 (en) * 2015-09-17 2021-10-21 Contrafect Corporation Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby
KR20190004799A (ko) * 2016-05-12 2019-01-14 콘트라펙트 코포레이션 항균 폴리펩티드의 최소 억제 농도를 평가 및 탐지하기 위한 배지미량희석법
SG11201811442UA (en) * 2016-06-20 2019-01-30 Isa Pharmaceuticals B V Formulation of a peptide vaccine
WO2020046747A1 (en) * 2018-08-23 2020-03-05 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
CN112368376A (zh) * 2018-03-29 2021-02-12 康特拉费克特公司 溶素-抗微生物肽(amp)多肽构建体、溶素、其分离的编码多核苷酸及其用途
US10988520B2 (en) * 2018-03-29 2021-04-27 Contrafect Corporation Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
US20210198644A1 (en) * 2018-05-23 2021-07-01 The Rockefeller University Recombinant lysins

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