JP2017525971A - ヘモグロビンにおける異常を検出する方法 - Google Patents

ヘモグロビンにおける異常を検出する方法 Download PDF

Info

Publication number
JP2017525971A
JP2017525971A JP2017511663A JP2017511663A JP2017525971A JP 2017525971 A JP2017525971 A JP 2017525971A JP 2017511663 A JP2017511663 A JP 2017511663A JP 2017511663 A JP2017511663 A JP 2017511663A JP 2017525971 A JP2017525971 A JP 2017525971A
Authority
JP
Japan
Prior art keywords
globin
sample
analysis
spectrum
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017511663A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017525971A5 (https=
Inventor
クルーゼ アイルズ,レイモンド
クルーゼ アイルズ,レイモンド
クルーゼ アイルズ,ジェイソン
クルーゼ アイルズ,ジェイソン
アバン,トーマス
マーガレット エリザベス ドチャーティ,スザンヌ
マーガレット エリザベス ドチャーティ,スザンヌ
ナーゼ,マフムード
Original Assignee
マップ アイピー ホールディング リミテッド
マップ アイピー ホールディング リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マップ アイピー ホールディング リミテッド, マップ アイピー ホールディング リミテッド filed Critical マップ アイピー ホールディング リミテッド
Publication of JP2017525971A publication Critical patent/JP2017525971A/ja
Publication of JP2017525971A5 publication Critical patent/JP2017525971A5/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2017511663A 2014-08-29 2015-08-27 ヘモグロビンにおける異常を検出する方法 Pending JP2017525971A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1415367.0 2014-08-29
GBGB1415367.0A GB201415367D0 (en) 2014-08-29 2014-08-29 Methods for detecting abnormalities in haemoglobin
PCT/GB2015/052491 WO2016030688A1 (en) 2014-08-29 2015-08-27 Method for detecting abnormalities in hemoglobin

Publications (2)

Publication Number Publication Date
JP2017525971A true JP2017525971A (ja) 2017-09-07
JP2017525971A5 JP2017525971A5 (https=) 2018-10-04

Family

ID=51752371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017511663A Pending JP2017525971A (ja) 2014-08-29 2015-08-27 ヘモグロビンにおける異常を検出する方法

Country Status (10)

Country Link
US (1) US10359431B2 (https=)
EP (1) EP3186640B1 (https=)
JP (1) JP2017525971A (https=)
CN (1) CN107110873B (https=)
CY (1) CY1122239T1 (https=)
DK (1) DK3186640T3 (https=)
ES (1) ES2751480T3 (https=)
GB (1) GB201415367D0 (https=)
PT (1) PT3186640T (https=)
WO (1) WO2016030688A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3047542A1 (en) * 2016-12-19 2018-06-28 The Uab Research Foundation Mass spectrometric standards for hemoglobin beta and hemoglobin beta sickle and uses thereof
WO2019022189A1 (ja) * 2017-07-27 2019-01-31 国立大学法人九州大学 グロビンタイピングペプチド
CN108062977A (zh) * 2017-12-18 2018-05-22 广东祥岳生物技术有限公司 一种新生儿地中海贫血筛查结果自动判断系统
CN110658251A (zh) * 2019-10-01 2020-01-07 长沙湘华质谱医学科技有限公司 表征地中海贫血症的特征蛋白组合物或质谱模型的用途
CN110632326A (zh) * 2019-10-01 2019-12-31 北京毅新博创生物科技有限公司 用于质谱诊断地中海贫血症的特征蛋白标记组合物及其诊断产品
CN110658252A (zh) * 2019-10-01 2020-01-07 长沙湘华质谱医学科技有限公司 用于质谱诊断地中海贫血症的特征蛋白质谱模型及其用途
CN111638261B (zh) * 2020-04-17 2023-04-07 融智生物科技(青岛)有限公司 一种计算设备、存储介质和地中海贫血筛查装置及系统
CN111948404B (zh) * 2020-08-03 2023-04-07 融智生物科技(青岛)有限公司 用于筛查地中海贫血的特征蛋白标记组合物、质谱模型及其应用
CN117825542B (zh) * 2022-05-11 2024-10-29 重庆医科大学附属儿童医院 血红蛋白病的标志物组合物及其筛查试剂与应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515159A (ja) * 2003-11-19 2007-06-14 ラボラトリーズ セローノ エス.エイ. 血管形成阻害分子、並びに癌の治療及び診断におけるその使用
JP2007263896A (ja) * 2006-03-29 2007-10-11 Univ Nagoya 肺癌患者の術後予後予測のための生物マーカー及びその方法
US20080108144A1 (en) * 2004-05-27 2008-05-08 Alam Muhammad A Method for the Rapid Analysis of Polypeptides
JP2008529027A (ja) * 2005-02-01 2008-07-31 キングス カレッジ ロンドン スクリーニング法
JP2008256713A (ja) * 2001-02-23 2008-10-23 Abx Sa 生物学的細胞の同定および計数のための方法
JP2009544941A (ja) * 2006-07-21 2009-12-17 アムジエン・インコーポレーテツド サンプル中のヘプシジンを検出および/または測定する方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492095A (en) * 1967-10-05 1970-01-27 Harold B Tillen Product for and method of testing blood for the presence of hemoglobin s
US4847209A (en) 1987-11-09 1989-07-11 Miles Inc. Latex agglutination immunoassay in the presence of hemoglobin
US20030003588A1 (en) * 2001-06-28 2003-01-02 Comper Wayne D. Method for kidney disease detection by protein profiling
US20040171026A1 (en) 2001-09-05 2004-09-02 Hochstrasser Denis Francois Diagnostic method for transmissible spongiform encephalopathies
FI20031370A0 (fi) * 2003-09-23 2003-09-23 Wallac Oy Automaattinen hemoglobiinin määritysmenetelmä vastasyntyneiden seulontaan
TW200538738A (en) 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
US8309313B2 (en) 2006-03-06 2012-11-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Glycated peptides and methods of use
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US9250248B2 (en) 2006-11-01 2016-02-02 The Johns Hopkins University Early detection of diabetes
JP2011515680A (ja) 2008-03-17 2011-05-19 ネルソン,ランドール,ダブリュ. 糖尿病のためのバイオマーカーおよびアッセイ
EP2294426A1 (en) 2008-05-27 2011-03-16 F. Hoffmann-La Roche AG Method for risk reduction in glycemic control
WO2011003182A1 (en) 2009-07-07 2011-01-13 University Of Victoria Innovation And Development Corporation Methods for early detection of blood disorders
SG195180A1 (en) * 2011-05-31 2013-12-30 Singapore Health Serv Pte Ltd Method for detecting disease biomarkers
CN103278574B (zh) * 2013-04-26 2014-12-10 首都医科大学附属北京朝阳医院 利用液相色谱串联三重四级杆质谱仪检测糖化血红蛋白的方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008256713A (ja) * 2001-02-23 2008-10-23 Abx Sa 生物学的細胞の同定および計数のための方法
JP2007515159A (ja) * 2003-11-19 2007-06-14 ラボラトリーズ セローノ エス.エイ. 血管形成阻害分子、並びに癌の治療及び診断におけるその使用
US20080108144A1 (en) * 2004-05-27 2008-05-08 Alam Muhammad A Method for the Rapid Analysis of Polypeptides
JP2008529027A (ja) * 2005-02-01 2008-07-31 キングス カレッジ ロンドン スクリーニング法
JP2007263896A (ja) * 2006-03-29 2007-10-11 Univ Nagoya 肺癌患者の術後予後予測のための生物マーカー及びその方法
JP2009544941A (ja) * 2006-07-21 2009-12-17 アムジエン・インコーポレーテツド サンプル中のヘプシジンを検出および/または測定する方法

Also Published As

Publication number Publication date
CY1122239T1 (el) 2020-11-25
ES2751480T3 (es) 2020-03-31
DK3186640T3 (da) 2019-10-21
US20180224462A1 (en) 2018-08-09
CN107110873B (zh) 2019-07-05
US10359431B2 (en) 2019-07-23
PT3186640T (pt) 2019-10-30
EP3186640B1 (en) 2019-07-24
EP3186640A1 (en) 2017-07-05
CN107110873A (zh) 2017-08-29
GB201415367D0 (en) 2014-10-15
WO2016030688A1 (en) 2016-03-03

Similar Documents

Publication Publication Date Title
JP2017525971A (ja) ヘモグロビンにおける異常を検出する方法
Warghade et al. Prevalence of hemoglobin variants and hemoglobinopathies using cation-exchange high-performance liquid chromatography in central reference laboratory of India: A report of 65779 cases
EP2971285B1 (en) Blood biomarkers that predict persistent cognitive dysfunction after concussion
EP3186641B1 (en) Rapid screening and evaluation of diabetes and prediabetes by glycated hemoglobin mass spectrometry
CA2596010C (en) Screening method for protein variant
HK1221768A1 (zh) 产前筛选
CN110632326A (zh) 用于质谱诊断地中海贫血症的特征蛋白标记组合物及其诊断产品
CN110658252A (zh) 用于质谱诊断地中海贫血症的特征蛋白质谱模型及其用途
AU2008332886A1 (en) Methods and compositions
CN111948404A (zh) 用于筛查地中海贫血的特征蛋白标记组合物、质谱模型及其应用
CN110658251A (zh) 表征地中海贫血症的特征蛋白组合物或质谱模型的用途
CN102401813B (zh) 变异血红素的快速分析方法
DE102018116353B4 (de) Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
CN116574795A (zh) 基于飞行时间质谱法的地中海贫血症基因分型引物组和试剂盒
Fan et al. Increase of plasma S100B level in patients with moderate and severe traumatic brain injury
Ali et al. A case of hemoglobin sickle-D Punjab
Kubba et al. Hyperprolactinemia Causes Primary and Secondary Infertility in Women of raqi Patients
Fabry et al. Laboratory methods for diagnosis and evaluation of hemoglobin disorders
EP4260070B1 (en) Diagnosis of autism spectrum disorder
Bhattarai et al. RETRACTED: Variation of HbA1c with Hemoglobin level: A comparative study betweenD10 Biorad (HpLC) and Nycocard (Immunochromatography) analyser.
BR112014003159B1 (pt) Método de diagnóstico sorológico neonatal
Ahmed et al. Hemoglobin N Seattle in a Bengali Child: Diagnostic Challenges and Insights into Genetic Diversity–A Case
El-Kashef Proteome-based diagnostics of SIDS: comparative quantitative analysis
Sivaraman Importance of awareness of elevated fetal hemoglobin (HbF) in HbA1c testing
Agostini et al. Multivariate analysis approach to the serum peptide profile of morbidly obese patients

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170602

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180821

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180821

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190423

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190426

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20191112