JP2017525770A5 - - Google Patents
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- Publication number
- JP2017525770A5 JP2017525770A5 JP2017530367A JP2017530367A JP2017525770A5 JP 2017525770 A5 JP2017525770 A5 JP 2017525770A5 JP 2017530367 A JP2017530367 A JP 2017530367A JP 2017530367 A JP2017530367 A JP 2017530367A JP 2017525770 A5 JP2017525770 A5 JP 2017525770A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substitution
- aryl
- compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2014903342A AU2014903342A0 (en) | 2014-08-25 | Mapk inhibitors | |
| AU2014903342 | 2014-08-25 | ||
| PCT/AU2015/050490 WO2016029263A1 (en) | 2014-08-25 | 2015-08-25 | Mapk inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017525770A JP2017525770A (ja) | 2017-09-07 |
| JP2017525770A5 true JP2017525770A5 (https=) | 2018-09-27 |
| JP6773655B2 JP6773655B2 (ja) | 2020-10-21 |
Family
ID=55398500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017530367A Active JP6773655B2 (ja) | 2014-08-25 | 2015-08-25 | Ｍａｐｋ阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20170266173A1 (https=) |
| EP (1) | EP3186245B1 (https=) |
| JP (1) | JP6773655B2 (https=) |
| CN (1) | CN107074831B (https=) |
| AU (1) | AU2015309687B2 (https=) |
| WO (1) | WO2016029263A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| IL326136A (en) | 2023-08-07 | 2026-03-01 | Revolution Medicines Inc | RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4174405A (en) * | 1974-02-25 | 1979-11-13 | Uniroyal, Inc. | Thiophenes useful in control of acarids |
| US4381311A (en) | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
| JPS57134480A (en) * | 1980-12-29 | 1982-08-19 | Du Pont | Antiinflammatory 4,5-diaryl-alpha- (polyhalomethyl)-2-thiophene methanols |
| US4749712A (en) * | 1983-03-01 | 1988-06-07 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 5-alkylthiophenes |
| GB9012936D0 (en) | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
| US6428571B1 (en) | 1996-01-22 | 2002-08-06 | Scimed Life Systems, Inc. | Self-sealing PTFE vascular graft and manufacturing methods |
| RU2222534C2 (ru) * | 1997-04-24 | 2004-01-27 | Орто-Макнейл Фармасьютикал, Инк. | Замещенные имидазолы, способ их получения, фармацевтическая композиция на их основе, способы лечения цитокин-опосредованных заболеваний |
| ES2296910T3 (es) * | 2001-01-22 | 2008-05-01 | Sankyo Company, Limited | Compuestos sustituidos con grupo amino biciclicos. |
| US6589997B2 (en) * | 2001-06-29 | 2003-07-08 | North Shore-Long Island Jewish Health System | Small-molecule modulators of hepatocyte growth factor/scatter factor activities |
| US6544373B2 (en) | 2001-07-26 | 2003-04-08 | United Microelectronics Corp. | Polishing pad for a chemical mechanical polishing process |
| US6835745B2 (en) * | 2002-01-15 | 2004-12-28 | Wyeth | Phenyl substituted thiophenes as estrogenic agents |
| DE10217270A1 (de) | 2002-04-18 | 2003-11-06 | Wella Ag | In 2-Stellung substituierte 3-Aminophenol-Derivate sowie diese Verbindungen enthaltende Färbemittel |
| US20040242673A1 (en) * | 2003-05-16 | 2004-12-02 | Ambit Biosciences Corporation | Heterocyclic compounds and uses thereof |
| DE10343757A1 (de) * | 2003-09-15 | 2005-04-21 | Univ Dresden Tech | Verfahren zur Schwermetall-freien Herstellung von N,N'-persubstituierten 5,5'-Diamino-2,2'bithiophenen und 2,2'-Diamino-5,5'-bithiazolen sowie deren Verwendung |
| JP2008001596A (ja) * | 2004-09-03 | 2008-01-10 | Astellas Pharma Inc | ナトリウムチャネル阻害剤 |
| US8835476B2 (en) * | 2005-03-04 | 2014-09-16 | Fan Wu | Synthesis of novel antimicrobials |
| RU2008112691A (ru) * | 2005-10-03 | 2009-10-10 | Оно Фармасьютикал Ко., Лтд. (Jp) | Азотсодержащее гетероциклическое соединение и его фармацевтическое применение |
| WO2007118149A2 (en) * | 2006-04-07 | 2007-10-18 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical Lollege | Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers |
| JP5572968B2 (ja) * | 2009-03-06 | 2014-08-20 | 大日本印刷株式会社 | 量子ドット発光材料、及び発光デバイス |
| CA2864085C (en) * | 2012-02-08 | 2021-11-23 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
-
2015
- 2015-08-25 WO PCT/AU2015/050490 patent/WO2016029263A1/en not_active Ceased
- 2015-08-25 EP EP15835823.4A patent/EP3186245B1/en active Active
- 2015-08-25 US US15/505,942 patent/US20170266173A1/en not_active Abandoned
- 2015-08-25 CN CN201580056652.XA patent/CN107074831B/zh active Active
- 2015-08-25 AU AU2015309687A patent/AU2015309687B2/en active Active
- 2015-08-25 JP JP2017530367A patent/JP6773655B2/ja active Active
-
2018
- 2018-06-12 US US16/006,308 patent/US11273153B2/en active Active
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