JP2017524017A5 - - Google Patents

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Publication number
JP2017524017A5
JP2017524017A5 JP2017507968A JP2017507968A JP2017524017A5 JP 2017524017 A5 JP2017524017 A5 JP 2017524017A5 JP 2017507968 A JP2017507968 A JP 2017507968A JP 2017507968 A JP2017507968 A JP 2017507968A JP 2017524017 A5 JP2017524017 A5 JP 2017524017A5
Authority
JP
Japan
Prior art keywords
alkyl
benzenesulfonamide
sulfonamide
fluoroquinolin
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017507968A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017524017A (ja
JP6770507B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/045174 external-priority patent/WO2016025779A1/en
Publication of JP2017524017A publication Critical patent/JP2017524017A/ja
Publication of JP2017524017A5 publication Critical patent/JP2017524017A5/ja
Application granted granted Critical
Publication of JP6770507B2 publication Critical patent/JP6770507B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017507968A 2014-08-14 2015-08-14 ユビキチン化阻害物質として有用なキノリン誘導体 Expired - Fee Related JP6770507B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462037449P 2014-08-14 2014-08-14
US62/037,449 2014-08-14
PCT/US2015/045174 WO2016025779A1 (en) 2014-08-14 2015-08-14 Quinoline derivatives useful as ubiquitination inhibitors

Publications (3)

Publication Number Publication Date
JP2017524017A JP2017524017A (ja) 2017-08-24
JP2017524017A5 true JP2017524017A5 (enExample) 2018-09-27
JP6770507B2 JP6770507B2 (ja) 2020-10-14

Family

ID=53938449

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017507968A Expired - Fee Related JP6770507B2 (ja) 2014-08-14 2015-08-14 ユビキチン化阻害物質として有用なキノリン誘導体

Country Status (5)

Country Link
US (1) US10040766B2 (enExample)
EP (1) EP3180328B1 (enExample)
JP (1) JP6770507B2 (enExample)
CA (1) CA2958142A1 (enExample)
WO (1) WO2016025779A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7198221B2 (ja) * 2017-04-20 2022-12-28 ゴーダーヴァリ バイオリファイナリーズ リミテッド 抗癌化合物
US11213701B2 (en) * 2018-12-01 2022-01-04 Russell Dahl Neuroprotective quinoline sulfonamides
EP4291555A1 (en) * 2021-02-09 2023-12-20 Celgene Corporation Sulfonamides and their use for treatment of helminthic infections and diseases
CN117865886B (zh) * 2024-03-07 2024-05-10 中国药科大学 一种n-(喹啉-8-基)喹啉-8-磺酰胺类化合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1651595A2 (en) * 2003-05-30 2006-05-03 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
US20070254894A1 (en) * 2006-01-10 2007-11-01 Kane John L Jr Novel small molecules with selective cytotoxicity against human microvascular endothelial cell proliferation
WO2008074068A1 (en) * 2006-12-20 2008-06-26 Prana Biotechnology Limited Substituted quinoline derivatives as antiamyloidogeneic agents
WO2009137597A1 (en) * 2008-05-06 2009-11-12 The Trustees Of Columbia University In The City Of New York COMPOUNDS THAT INHIBIT PRODUCTION OF sAPPβ AND Aβ AND USES THEREOF
WO2010051064A1 (en) * 2008-10-30 2010-05-06 The Trustees Of Columbia University In The City Of New York COMPOUNDS THAT INHIBIT NFκB ACTIVITY
US20120214803A1 (en) * 2011-02-18 2012-08-23 Vifor (International) Ag Novel Sulfonaminoquinoline Hepcidin Antagonists
WO2012122534A2 (en) 2011-03-10 2012-09-13 The Trustees Of Columbia University In The City Of New York N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation
US9200046B2 (en) * 2011-06-29 2015-12-01 Cornell University Reporter system for high throughput screening of compounds and uses thereof
WO2013052943A2 (en) * 2011-10-06 2013-04-11 The Regents Of The University Of Michgian Small molecule inhibitors of mcl-1 and uses thereof

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