JP2017523955A5 - - Google Patents
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- Publication number
- JP2017523955A5 JP2017523955A5 JP2016573603A JP2016573603A JP2017523955A5 JP 2017523955 A5 JP2017523955 A5 JP 2017523955A5 JP 2016573603 A JP2016573603 A JP 2016573603A JP 2016573603 A JP2016573603 A JP 2016573603A JP 2017523955 A5 JP2017523955 A5 JP 2017523955A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- desmopressin
- gum
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims description 32
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 claims description 17
- 150000003839 salts Chemical group 0.000 claims description 16
- 229960004281 desmopressin Drugs 0.000 claims description 14
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 10
- 239000004480 active ingredient Substances 0.000 claims description 8
- 238000004925 denaturation Methods 0.000 claims description 8
- 230000036425 denaturation Effects 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 238000003505 heat denaturation Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 4
- 239000003381 stabilizer Substances 0.000 claims description 4
- FIEYHAAMDAPVCH-UHFFFAOYSA-N 2-methyl-1h-quinazolin-4-one Chemical group C1=CC=C2NC(C)=NC(=O)C2=C1 FIEYHAAMDAPVCH-UHFFFAOYSA-N 0.000 claims description 3
- 229960002845 desmopressin acetate Drugs 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 210000000214 mouth Anatomy 0.000 claims description 2
- 206010029446 nocturia Diseases 0.000 claims description 2
- 230000002265 prevention Effects 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 208000008967 Enuresis Diseases 0.000 claims 1
- 208000005346 nocturnal enuresis Diseases 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 description 3
- 230000000422 nocturnal effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020140073067 | 2014-06-16 | ||
| KR1020140073067A KR20150144209A (ko) | 2014-06-16 | 2014-06-16 | 안정화된 데스모프레신 또는 이의 약학적으로 허용가능한 염을 함유 약학 조성물 |
| PCT/EP2015/063347 WO2015193246A1 (en) | 2014-06-16 | 2015-06-15 | Stabilized desmopressin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017523955A JP2017523955A (ja) | 2017-08-24 |
| JP2017523955A5 true JP2017523955A5 (enExample) | 2018-07-19 |
| JP6615130B2 JP6615130B2 (ja) | 2019-12-04 |
Family
ID=53510836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573603A Active JP6615130B2 (ja) | 2014-06-16 | 2015-06-15 | 安定化デスモプレシン |
Country Status (33)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114432424B (zh) * | 2021-12-27 | 2023-06-27 | 南通联亚药业股份有限公司 | 一种稳定的铝塑包装去氨加压素片剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
| GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| DE60307082T4 (de) * | 2002-05-07 | 2015-04-30 | Ferring B.V. | In der mundhöhle dispergierbare phamarzeutische zusammensetzung mit desmopressin |
| WO2007083323A2 (en) * | 2006-01-23 | 2007-07-26 | Panacea Biotec Limited. | Modified release oral dosage form comprising desmopressin |
| CN100463674C (zh) * | 2006-12-22 | 2009-02-25 | 江苏奥赛康药业有限公司 | 一种氯雷他定口腔速溶膜及其制备方法 |
| US20150306170A1 (en) * | 2012-11-21 | 2015-10-29 | Ferring B.V. | Composition for immediate and extended release |
| TW201422254A (zh) * | 2012-11-21 | 2014-06-16 | Ferring Bv | 用於速釋及延釋的組成物 |
-
2014
- 2014-06-16 KR KR1020140073067A patent/KR20150144209A/ko active Pending
-
2015
- 2015-06-15 SG SG11201609374YA patent/SG11201609374YA/en unknown
- 2015-06-15 HR HRP20191746TT patent/HRP20191746T1/hr unknown
- 2015-06-15 NZ NZ727388A patent/NZ727388A/en unknown
- 2015-06-15 PL PL15734080T patent/PL3154516T3/pl unknown
- 2015-06-15 UA UAA201700344A patent/UA119776C2/uk unknown
- 2015-06-15 EA EA201692556A patent/EA032834B1/ru not_active IP Right Cessation
- 2015-06-15 JP JP2016573603A patent/JP6615130B2/ja active Active
- 2015-06-15 KR KR1020177001134A patent/KR102360656B1/ko active Active
- 2015-06-15 MX MX2016016635A patent/MX374540B/es active IP Right Grant
- 2015-06-15 ES ES15734080T patent/ES2751600T3/es active Active
- 2015-06-15 US US15/318,683 patent/US20170128521A1/en not_active Abandoned
- 2015-06-15 WO PCT/EP2015/063347 patent/WO2015193246A1/en not_active Ceased
- 2015-06-15 EP EP15734080.3A patent/EP3154516B1/en active Active
- 2015-06-15 SG SG10201811139UA patent/SG10201811139UA/en unknown
- 2015-06-15 LT LT15734080T patent/LT3154516T/lt unknown
- 2015-06-15 AU AU2015276247A patent/AU2015276247C1/en active Active
- 2015-06-15 PT PT157340803T patent/PT3154516T/pt unknown
- 2015-06-15 MY MYPI2016704613A patent/MY182781A/en unknown
- 2015-06-15 SI SI201530936T patent/SI3154516T1/sl unknown
- 2015-06-15 DK DK15734080.3T patent/DK3154516T3/da active
- 2015-06-15 HU HUE15734080A patent/HUE045395T2/hu unknown
- 2015-06-15 CN CN201580032230.9A patent/CN106456706B/zh active Active
- 2015-06-15 TN TN2016000561A patent/TN2016000561A1/en unknown
- 2015-06-15 RS RSP20191285 patent/RS59449B1/sr unknown
- 2015-06-15 CA CA2951768A patent/CA2951768C/en active Active
- 2015-06-16 AR ARP150101907A patent/AR100850A1/es not_active Application Discontinuation
- 2015-06-16 TW TW104119405A patent/TWI670070B/zh active
- 2015-06-16 JO JOP/2015/0148A patent/JO3500B1/ar active
-
2016
- 2016-11-18 ZA ZA2016/08020A patent/ZA201608020B/en unknown
- 2016-12-13 SA SA516380492A patent/SA516380492B1/ar unknown
- 2016-12-13 IL IL249538A patent/IL249538A0/en unknown
- 2016-12-15 CL CL2016003219A patent/CL2016003219A1/es unknown
- 2016-12-16 PH PH12016502527A patent/PH12016502527B1/en unknown
-
2017
- 2017-01-16 CO CONC2017/0000354A patent/CO2017000354A2/es unknown
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