JP2017518375A5 - - Google Patents
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- Publication number
- JP2017518375A5 JP2017518375A5 JP2017516031A JP2017516031A JP2017518375A5 JP 2017518375 A5 JP2017518375 A5 JP 2017518375A5 JP 2017516031 A JP2017516031 A JP 2017516031A JP 2017516031 A JP2017516031 A JP 2017516031A JP 2017518375 A5 JP2017518375 A5 JP 2017518375A5
- Authority
- JP
- Japan
- Prior art keywords
- mhc
- molecule
- major histocompatibility
- multimeric
- histocompatibility complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108700018351 Major Histocompatibility Complex Proteins 0.000 claims 46
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 claims 46
- 238000000034 method Methods 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 7
- 239000002773 nucleotide Substances 0.000 claims 7
- 125000003729 nucleotide group Chemical group 0.000 claims 7
- 239000000427 antigen Substances 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 4
- 108010090804 Streptavidin Proteins 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 2
- 108090001008 Avidin Proteins 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 229920001503 Glucan Polymers 0.000 claims 1
- 102000008949 Histocompatibility Antigens Class I Human genes 0.000 claims 1
- 108010088652 Histocompatibility Antigens Class I Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Natural products N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000005859 cell recognition Effects 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 238000012350 deep sequencing Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000001943 fluorescence-activated cell sorting Methods 0.000 claims 1
- 238000002523 gelfiltration Methods 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 238000012165 high-throughput sequencing Methods 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 150000001455 metallic ions Chemical class 0.000 claims 1
- 239000013642 negative control Substances 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 230000004043 responsiveness Effects 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 238000001179 sorption measurement Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201470340 | 2014-06-06 | ||
| DKPA201470340 | 2014-06-06 | ||
| PCT/DK2015/050150 WO2015185067A1 (en) | 2014-06-06 | 2015-06-08 | Determining antigen recognition through barcoding of mhc multimers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020043059A Division JP7271465B2 (ja) | 2014-06-06 | 2020-03-12 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017518375A JP2017518375A (ja) | 2017-07-06 |
| JP2017518375A5 true JP2017518375A5 (enExample) | 2018-07-12 |
| JP6956632B2 JP6956632B2 (ja) | 2021-11-02 |
Family
ID=59272565
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017516031A Active JP6956632B2 (ja) | 2014-06-06 | 2015-06-08 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
| JP2020043059A Active JP7271465B2 (ja) | 2014-06-06 | 2020-03-12 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
| JP2023072013A Pending JP2023100746A (ja) | 2014-06-06 | 2023-04-26 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
| JP2025092283A Pending JP2025128229A (ja) | 2014-06-06 | 2025-06-03 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020043059A Active JP7271465B2 (ja) | 2014-06-06 | 2020-03-12 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
| JP2023072013A Pending JP2023100746A (ja) | 2014-06-06 | 2023-04-26 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
| JP2025092283A Pending JP2025128229A (ja) | 2014-06-06 | 2025-06-03 | Ｍｈｃ多量体のバーコード標識による抗原認識の判定 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20170343545A1 (enExample) |
| EP (3) | EP4484450A3 (enExample) |
| JP (4) | JP6956632B2 (enExample) |
| AU (3) | AU2015271324B2 (enExample) |
| CA (2) | CA2951325C (enExample) |
| DK (1) | DK3152232T3 (enExample) |
| ES (1) | ES2770634T3 (enExample) |
| PT (1) | PT3152232T (enExample) |
| SG (2) | SG11201610177UA (enExample) |
| WO (1) | WO2015185067A1 (enExample) |
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| CA2951325C (en) | 2014-06-06 | 2023-09-12 | Herlev Hospital | Determining antigen recognition through barcoding of mhc multimers |
| WO2015188839A2 (en) * | 2014-06-13 | 2015-12-17 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
| US9789974B2 (en) | 2015-10-19 | 2017-10-17 | Goodrich Corporation | Brake monitoring system |
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2015
- 2015-06-08 CA CA2951325A patent/CA2951325C/en active Active
- 2015-06-08 AU AU2015271324A patent/AU2015271324B2/en active Active
- 2015-06-08 US US15/316,584 patent/US20170343545A1/en active Pending
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- 2015-06-08 DK DK15739508.8T patent/DK3152232T3/da active
- 2015-06-08 EP EP15739508.8A patent/EP3152232B1/en not_active Revoked
- 2015-06-08 PT PT157395088T patent/PT3152232T/pt unknown
- 2015-06-08 WO PCT/DK2015/050150 patent/WO2015185067A1/en not_active Ceased
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