JP2017518348A - Ｉｒａｋ４阻害剤としての置換インダゾール化合物 - Google Patents

Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Download PDF

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JP2017518348A
JP2017518348A JP2016574004A JP2016574004A JP2017518348A JP 2017518348 A JP2017518348 A JP 2017518348A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2017518348 A JP2017518348 A JP 2017518348A
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optionally substituted
mmol
disease
compound
methyl
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JP2017518348A5 (enExample
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ラオ ガマディ，ベンケイツワー
ラオ ガマディ，ベンケイツワー
サマジダール，スサンタ
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Aurigene Oncology Ltd
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Aurigene Discovery Technologies Ltd
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016574004A 2014-06-20 2015-06-19 Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Pending JP2017518348A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3017CH2014 2014-06-20
IN3017/CHE/2014 2014-06-20
PCT/IB2015/054620 WO2015193846A1 (en) 2014-06-20 2015-06-19 Substituted indazole compounds as irak4 inhibitors

Publications (2)

Publication Number Publication Date
JP2017518348A true JP2017518348A (ja) 2017-07-06
JP2017518348A5 JP2017518348A5 (enExample) 2018-08-02

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JP2016574004A Pending JP2017518348A (ja) 2014-06-20 2015-06-19 Ｉｒａｋ４阻害剤としての置換インダゾール化合物

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Country Link
US (1) US20170152263A1 (enExample)
EP (1) EP3157521A4 (enExample)
JP (1) JP2017518348A (enExample)
KR (1) KR20170016500A (enExample)
CN (1) CN106456609A (enExample)
AU (1) AU2015275730A1 (enExample)
BR (1) BR112016029853A2 (enExample)
CA (1) CA2952188A1 (enExample)
CU (1) CU20160188A7 (enExample)
EA (1) EA201692418A1 (enExample)
HK (1) HK1231411A1 (enExample)
IL (1) IL249345A0 (enExample)
MX (1) MX2016017147A (enExample)
PH (1) PH12016502382A1 (enExample)
SG (1) SG11201610009XA (enExample)
WO (1) WO2015193846A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503357A (ja) * 2015-12-22 2019-02-07 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ＩＲＡＫ４調節因子としてのピラゾロ［１，５ａ］ピリミジン誘導体
JP2024500247A (ja) * 2020-12-25 2024-01-05 メッドシャイン ディスカバリー インコーポレイテッド アミドオキサゾール系化合物
JP2025502802A (ja) * 2021-12-31 2025-01-28 アクロ バイオサイエンス （エイチケー） リミテッド Ｉｒａｋ４阻害剤としてのヘテロアリール化合物、その組成物および用途

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20181795T1 (hr) 2014-01-13 2019-01-25 Aurigene Discovery Technologies Limited Biciklički heterociklilni derivati kao inhibitori irak4
JO3705B1 (ar) 2014-11-26 2021-01-31 Bayer Pharma AG إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
UY36660A (es) 2015-04-30 2016-11-30 Bayer Pharma AG Combinaciones de inhibidores de irak4
EP3195865A1 (de) 2016-01-25 2017-07-26 Bayer Pharma Aktiengesellschaft Kombinationen von irak4 inhibitoren und btk inhibitoren
EA201890307A1 (ru) * 2015-07-15 2018-10-31 Ориджин Дискавери Текнолоджиз Лимитед Индазольные и азаиндазольные соединения как ингибиторы irak-4
US10435396B2 (en) 2016-03-03 2019-10-08 Bayer Pharma Aktiegesellschaft 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs
AU2017272505B9 (en) 2016-06-01 2021-10-28 Bayer Pharma Aktiengesellschaft Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals
CN109152771B (zh) * 2016-06-01 2022-07-19 拜耳医药股份有限公司 2-取代的吲唑用于治疗和预防自身免疫疾病的用途
AR109595A1 (es) 2016-09-09 2018-12-26 Incyte Corp Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
UA125650C2 (uk) 2016-09-09 2022-05-11 Інсайт Корпорейшн Регулятори нрk1 на основі похідних піразолопіридину та їх застосування для лікування раку
WO2018049214A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
EP3535273A1 (en) 2016-11-02 2019-09-11 H. Hoffnabb-La Roche Ag PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
US20180228786A1 (en) 2017-02-15 2018-08-16 Incyte Corporation Pyrazolopyridine compounds and uses thereof
JOP20180011A1 (ar) 2017-02-16 2019-01-30 Gilead Sciences Inc مشتقات بيرولو [1، 2-b]بيريدازين
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