JP2017518348A - Ｉｒａｋ４阻害剤としての置換インダゾール化合物 - Google Patents

Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Download PDF

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JP2017518348A
JP2017518348A JP2016574004A JP2016574004A JP2017518348A JP 2017518348 A JP2017518348 A JP 2017518348A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2017518348 A JP2017518348 A JP 2017518348A
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optionally substituted
mmol
disease
compound
methyl
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JP2017518348A5 (enExample
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ラオ ガマディ，ベンケイツワー
ラオ ガマディ，ベンケイツワー
サマジダール，スサンタ
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Aurigene Oncology Ltd
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Aurigene Discovery Technologies Ltd
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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016574004A 2014-06-20 2015-06-19 Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Pending JP2017518348A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3017CH2014 2014-06-20
IN3017/CHE/2014 2014-06-20
PCT/IB2015/054620 WO2015193846A1 (en) 2014-06-20 2015-06-19 Substituted indazole compounds as irak4 inhibitors

Publications (2)

Publication Number Publication Date
JP2017518348A true JP2017518348A (ja) 2017-07-06
JP2017518348A5 JP2017518348A5 (enExample) 2018-08-02

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JP2016574004A Pending JP2017518348A (ja) 2014-06-20 2015-06-19 Ｉｒａｋ４阻害剤としての置換インダゾール化合物

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Country Link
US (1) US20170152263A1 (enExample)
EP (1) EP3157521A4 (enExample)
JP (1) JP2017518348A (enExample)
KR (1) KR20170016500A (enExample)
CN (1) CN106456609A (enExample)
AU (1) AU2015275730A1 (enExample)
BR (1) BR112016029853A2 (enExample)
CA (1) CA2952188A1 (enExample)
CU (1) CU20160188A7 (enExample)
EA (1) EA201692418A1 (enExample)
HK (1) HK1231411A1 (enExample)
IL (1) IL249345A0 (enExample)
MX (1) MX2016017147A (enExample)
PH (1) PH12016502382A1 (enExample)
SG (1) SG11201610009XA (enExample)
WO (1) WO2015193846A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503357A (ja) * 2015-12-22 2019-02-07 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ＩＲＡＫ４調節因子としてのピラゾロ［１，５ａ］ピリミジン誘導体
JP2024500247A (ja) * 2020-12-25 2024-01-05 メッドシャイン ディスカバリー インコーポレイテッド アミドオキサゾール系化合物
JP2025502802A (ja) * 2021-12-31 2025-01-28 アクロ バイオサイエンス （エイチケー） リミテッド Ｉｒａｋ４阻害剤としてのヘテロアリール化合物、その組成物および用途

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL311677B2 (en) 2014-01-13 2025-06-01 Aurigene Oncology Ltd Bicyclic heterocyclyl derivatives as irak4 inhibitors
JO3705B1 (ar) 2014-11-26 2021-01-31 Bayer Pharma AG إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
WO2016174183A1 (en) 2015-04-30 2016-11-03 Bayer Pharma Aktiengesellschaft Combinations of inhibitors of irak4 with inhibitors of btk
EP3195865A1 (de) 2016-01-25 2017-07-26 Bayer Pharma Aktiengesellschaft Kombinationen von irak4 inhibitoren und btk inhibitoren
CA2992406A1 (en) * 2015-07-15 2017-01-19 Aurigene Discovery Technologies Limited Indazole and azaindazole compounds as irak-4 inhibitors
US10435396B2 (en) 2016-03-03 2019-10-08 Bayer Pharma Aktiegesellschaft 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs
WO2017207386A1 (de) 2016-06-01 2017-12-07 Bayer Pharma Aktiengesellschaft Verwendung von 2-substituierten indazolen zur behandlung und prophylaxe von autoimmunerkrankungen
SI3464266T1 (sl) 2016-06-01 2021-12-31 Bayer Animal Health Gmbh Substituirani indazoli, uporabni pri zdravljenju in preprečevanju alergijskih in/ali vnetnih bolezni pri živalih
US20180072718A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyridine compounds and uses thereof
US20180072741A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyrimidine compounds and uses thereof
AR109596A1 (es) 2016-09-09 2018-12-26 Incyte Corp Compuestos pirazolopiridina y sus usos
WO2018083085A1 (en) 2016-11-02 2018-05-11 F. Hoffmann-La Roche Ag PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
WO2018152220A1 (en) 2017-02-15 2018-08-23 Incyte Corporation Pyrazolopyridine compounds and uses thereof
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