JP2017517506A - 癌を処置するための抗ccr4抗体および4−1bbアゴニストの併用 - Google Patents
癌を処置するための抗ccr4抗体および4−1bbアゴニストの併用 Download PDFInfo
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- JP2017517506A JP2017517506A JP2016568497A JP2016568497A JP2017517506A JP 2017517506 A JP2017517506 A JP 2017517506A JP 2016568497 A JP2016568497 A JP 2016568497A JP 2016568497 A JP2016568497 A JP 2016568497A JP 2017517506 A JP2017517506 A JP 2017517506A
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462001534P | 2014-05-21 | 2014-05-21 | |
| US62/001,534 | 2014-05-21 | ||
| PCT/US2015/031081 WO2015179236A1 (en) | 2014-05-21 | 2015-05-15 | Combination of an anti-ccr4 antibody and a 4-1bb agonist for treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017517506A true JP2017517506A (ja) | 2017-06-29 |
| JP2017517506A5 JP2017517506A5 (OSRAM) | 2018-07-12 |
Family
ID=53284562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016568497A Pending JP2017517506A (ja) | 2014-05-21 | 2015-05-15 | 癌を処置するための抗ccr4抗体および4−1bbアゴニストの併用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10023649B2 (OSRAM) |
| EP (1) | EP3145956A1 (OSRAM) |
| JP (1) | JP2017517506A (OSRAM) |
| KR (1) | KR20170004006A (OSRAM) |
| CN (1) | CN106413751A (OSRAM) |
| AU (1) | AU2015264528A1 (OSRAM) |
| BR (1) | BR112016026993A2 (OSRAM) |
| CA (1) | CA2949214A1 (OSRAM) |
| IL (1) | IL248540A0 (OSRAM) |
| MX (1) | MX2016015181A (OSRAM) |
| RU (1) | RU2016146993A (OSRAM) |
| WO (1) | WO2015179236A1 (OSRAM) |
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|---|---|---|---|---|
| CN105979961B (zh) * | 2014-02-05 | 2020-12-18 | 西达-赛奈医疗中心 | 用于治疗癌症和感染性疾病的方法和组合物 |
| KR101503341B1 (ko) | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
| EP3408294A1 (en) * | 2016-01-25 | 2018-12-05 | Pfizer Inc. | Combination of an ox40 agonist and a 4-1bb agonist monoclonal antibody for treating cancer |
| BR112018076260A2 (pt) | 2016-06-20 | 2019-03-26 | Kymab Limited | anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina |
| IL300095A (en) * | 2016-11-23 | 2023-03-01 | Translational Drug Dev Llc | Benzamide and tumor necrosis factor receptor superfamily agonist compositions and uses thereof |
| AU2018206015B2 (en) | 2017-01-06 | 2019-05-30 | Eutilex Co., Ltd. | Anti-human 4-1 BB antibodies and use thereof |
| EP3431105B1 (en) | 2017-03-29 | 2020-01-01 | Shionogi&Co., Ltd. | Medicinal composition for treating cancer |
| JP7657023B2 (ja) | 2017-06-09 | 2025-04-04 | プロビデンス ヘルス アンド サービシーズ-オレゴン | がんの処置のための腫瘍反応性ヒトt細胞の同定のためのcd39およびcd103の使用 |
| EP3652209A2 (en) | 2017-07-11 | 2020-05-20 | Compass Therapeutics LLC | Agonist antibodies that bind human cd137 and uses thereof |
| WO2019072274A1 (zh) * | 2017-10-12 | 2019-04-18 | 瑞阳(苏州)生物科技有限公司 | 一种激动型4-1bb单克隆抗体 |
| CN109651507B (zh) | 2017-10-12 | 2021-11-26 | 瑞阳(苏州)生物科技有限公司 | 一种激动型4-1bb单克隆抗体 |
| WO2019089753A2 (en) | 2017-10-31 | 2019-05-09 | Compass Therapeutics Llc | Cd137 antibodies and pd-1 antagonists and uses thereof |
| WO2019090272A1 (en) | 2017-11-06 | 2019-05-09 | Flx Bio, Inc. | Chemokine receptor modulators for treatment of epstein barr virus positive cancer |
| US11851497B2 (en) | 2017-11-20 | 2023-12-26 | Compass Therapeutics Llc | CD137 antibodies and tumor antigen-targeting antibodies and uses thereof |
| WO2019109238A1 (en) * | 2017-12-05 | 2019-06-13 | Lyvgen Biopharma Co., Ltd. | Anti-cd137 antibodies and uses thereof |
| EP3744734A1 (en) * | 2018-01-22 | 2020-12-02 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-4-1bb antibody, antigen-binding fragment thereof and medical use thereof |
| MX2020009468A (es) * | 2018-03-13 | 2020-10-22 | Hoffmann La Roche | Terapias de combinacion de agonistas de 4-1bb con anticuerpos anti-cd20. |
| US12054554B2 (en) | 2018-04-10 | 2024-08-06 | Wuxi Biologics (Shanghai) Co., Ltd. | Monoclonal antibody against human 4-1BB, method for preparing the same, and use thereof |
| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| AU2019312200B2 (en) | 2018-07-23 | 2024-11-14 | Heidelberg Pharma Research Gmbh | Use of anti-CD137 antibody drug conjugate (ADC) in allogeneic cell therapy |
| WO2020216947A1 (en) | 2019-04-24 | 2020-10-29 | Heidelberg Pharma Research Gmbh | Amatoxin antibody-drug conjugates and uses thereof |
| MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
| JP7682102B2 (ja) | 2019-05-10 | 2025-05-23 | リビジェン バイオファーマ ホールディングス リミテッド | ヒト化抗cd137抗体およびその使用 |
| US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| KR20220127859A (ko) * | 2020-01-13 | 2022-09-20 | 사이토딘 인크. | Ccr5 양성 전이성 암 치료를 위한 ccr5 결합제 |
| CN115135344A (zh) * | 2020-02-04 | 2022-09-30 | 健玛保 | 在疗法中使用的抗体 |
| BR112022014623A2 (pt) * | 2020-02-14 | 2022-09-13 | Jounce Therapeutics Inc | Anticorpos e proteínas de fusão que se ligam a ccr8 e usos dos mesmos |
| US20230355804A1 (en) | 2020-06-29 | 2023-11-09 | Flagship Pioneering Innovations V, Inc. | Viruses engineered to promote thanotransmission and their use in treating cancer |
| EP4228627A4 (en) * | 2020-10-13 | 2024-11-06 | Board of Regents, The University of Texas System | COMBINATORIAL IMMUNOTHERAPEUTIC METHODS AND COMPOSITIONS FOR THE TREATMENT OF PANCREATIC DUCT ADENOCARCINOMA |
| CA3214085A1 (en) | 2021-03-31 | 2022-10-06 | Darby Rye Schmidt | Thanotransmission polypeptides and their use in treating cancer |
| CA3218590A1 (en) | 2021-06-07 | 2022-12-15 | Providence Health & Services - Oregon | Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use |
| KR20240026507A (ko) | 2021-06-29 | 2024-02-28 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 타노트랜스미션을 촉진시키도록 엔지니어링된 면역 세포 및 이의 용도 |
| IL309856A (en) | 2021-07-14 | 2024-02-01 | Genentech Inc | Antibodies anti-C-C motif receptor 8 (CCR8) and methods of use |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
| WO2025145207A1 (en) | 2023-12-29 | 2025-07-03 | Bristol-Myers Squibb Company | Combination therapy of kras inhibitor and treg-depleting agent |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| ATE477273T1 (de) | 1998-12-01 | 2010-08-15 | Facet Biotech Corp | Humanisierte antikoerper gegen gamma-interferon |
| CN1296960A (zh) * | 1999-11-22 | 2001-05-30 | 上海博容基因开发有限公司 | 一种新的多肽——人ccr4相关蛋白31和编码这种多肽的多核苷酸 |
| DK1449850T3 (da) | 2001-08-31 | 2011-02-14 | Kyowa Hakko Kirin Co Ltd | Humane CDR-graftede antistoffer eller antistoffragmenter deraf |
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- 2015-05-15 MX MX2016015181A patent/MX2016015181A/es unknown
- 2015-05-15 JP JP2016568497A patent/JP2017517506A/ja active Pending
- 2015-05-15 AU AU2015264528A patent/AU2015264528A1/en not_active Abandoned
- 2015-05-15 KR KR1020167035347A patent/KR20170004006A/ko not_active Withdrawn
- 2015-05-15 RU RU2016146993A patent/RU2016146993A/ru not_active Application Discontinuation
- 2015-05-15 US US15/312,515 patent/US10023649B2/en not_active Expired - Fee Related
- 2015-05-15 CA CA2949214A patent/CA2949214A1/en not_active Abandoned
- 2015-05-15 BR BR112016026993A patent/BR112016026993A2/pt not_active Application Discontinuation
- 2015-05-15 EP EP15727159.4A patent/EP3145956A1/en not_active Withdrawn
- 2015-05-15 WO PCT/US2015/031081 patent/WO2015179236A1/en not_active Ceased
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2016
- 2016-10-27 IL IL248540A patent/IL248540A0/en unknown
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| BLOOD, vol. 117, no. 8, JPN6019006379, 2011, pages 2423 - 2432, ISSN: 0004144381 * |
| CANCER IMMUNOLOGY IMMUNOTHERAPY, vol. 61, no. 10, JPN6019006376, 2012, pages 1721 - 1733, ISSN: 0004144379 * |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2015179236A1 (en) | 2015-11-26 |
| MX2016015181A (es) | 2017-05-25 |
| RU2016146993A (ru) | 2018-06-21 |
| US10023649B2 (en) | 2018-07-17 |
| IL248540A0 (en) | 2016-12-29 |
| CA2949214A1 (en) | 2015-11-26 |
| AU2015264528A1 (en) | 2016-11-03 |
| BR112016026993A2 (pt) | 2017-10-31 |
| US20170088627A1 (en) | 2017-03-30 |
| KR20170004006A (ko) | 2017-01-10 |
| CN106413751A (zh) | 2017-02-15 |
| EP3145956A1 (en) | 2017-03-29 |
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