|
JPH055425Y2
(enExample)
|
1986-05-20 |
1993-02-12 |
|
|
|
US5547839A
(en)
|
1989-06-07 |
1996-08-20 |
Affymax Technologies N.V. |
Sequencing of surface immobilized polymers utilizing microflourescence detection
|
|
JPH07508342A
(ja)
|
1992-04-22 |
1995-09-14 |
エコール ポリテクニーク フェデラル ドゥ ローザンヌ（エーペーエフエル） |
脂質膜センサー
|
|
GB9315847D0
(en)
|
1993-07-30 |
1993-09-15 |
Isis Innovation |
Tag reagent and assay method
|
|
US20120160687A1
(en)
|
1995-03-17 |
2012-06-28 |
President And Fellows Of Harvard College |
Characterization of individual polymer molecules based on monomer-interface interactions
|
|
US5795782A
(en)
|
1995-03-17 |
1998-08-18 |
President & Fellows Of Harvard College |
Characterization of individual polymer molecules based on monomer-interface interactions
|
|
US6362002B1
(en)
|
1995-03-17 |
2002-03-26 |
President And Fellows Of Harvard College |
Characterization of individual polymer molecules based on monomer-interface interactions
|
|
US6046005A
(en)
|
1997-01-15 |
2000-04-04 |
Incyte Pharmaceuticals, Inc. |
Nucleic acid sequencing with solid phase capturable terminators comprising a cleavable linking group
|
|
US5876936A
(en)
|
1997-01-15 |
1999-03-02 |
Incyte Pharmaceuticals, Inc. |
Nucleic acid sequencing with solid phase capturable terminators
|
|
US5804386A
(en)
|
1997-01-15 |
1998-09-08 |
Incyte Pharmaceuticals, Inc. |
Sets of labeled energy transfer fluorescent primers and their use in multi component analysis
|
|
US6485703B1
(en)
|
1998-07-31 |
2002-11-26 |
The Texas A&M University System |
Compositions and methods for analyte detection
|
|
US6267872B1
(en)
|
1998-11-06 |
2001-07-31 |
The Regents Of The University Of California |
Miniature support for thin films containing single channels or nanopores and methods for using same
|
|
JP4638043B2
(ja)
*
|
1998-12-14 |
2011-02-23 |
パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド |
ポリメラーゼ合成による、単一分子の核酸の配列決定のためのシステムおよび方法
|
|
US20030054360A1
(en)
|
1999-01-19 |
2003-03-20 |
Larry Gold |
Method and apparatus for the automated generation of nucleic acid ligands
|
|
US6399335B1
(en)
|
1999-11-16 |
2002-06-04 |
Advanced Research And Technology Institute, Inc. |
γ-phosphoester nucleoside triphosphates
|
|
US6383749B2
(en)
|
1999-12-02 |
2002-05-07 |
Clontech Laboratories, Inc. |
Methods of labeling nucleic acids for use in array based hybridization assays
|
|
EP2083015B1
(en)
|
2000-02-11 |
2016-04-06 |
The Texas A & M University System |
Biosensor compositions and methods of use
|
|
US6616895B2
(en)
|
2000-03-23 |
2003-09-09 |
Advanced Research Corporation |
Solid state membrane channel device for the measurement and characterization of atomic and molecular sized samples
|
|
US6413792B1
(en)
|
2000-04-24 |
2002-07-02 |
Eagle Research Development, Llc |
Ultra-fast nucleic acid sequencing device and a method for making and using the same
|
|
US6936702B2
(en)
|
2000-06-07 |
2005-08-30 |
Li-Cor, Inc. |
Charge-switch nucleotides
|
|
AU2001268291A1
(en)
|
2000-06-07 |
2001-12-17 |
Li-Cor, Inc. |
Charge-switch nucleotides
|
|
EP1307469B1
(en)
|
2000-08-03 |
2008-01-23 |
Boehringer Mannheim Gmbh |
Nucleic acid binding compounds containing pyrazolo¬3,4-d pyrimidine analogues of purin-2,6-diamine and their uses
|
|
US20060057565A1
(en)
|
2000-09-11 |
2006-03-16 |
Jingyue Ju |
Combinatorial fluorescence energy transfer tags and uses thereof
|
|
US6627748B1
(en)
|
2000-09-11 |
2003-09-30 |
The Trustees Of Columbia University In The City Of New York |
Combinatorial fluorescence energy transfer tags and their applications for multiplex genetic analyses
|
|
CA2421582A1
(en)
|
2000-09-11 |
2002-03-21 |
The Trustees Of Columbia University In The City Of New York |
Combinatorial fluorescence energy transfer tags and uses thereof
|
|
US9708358B2
(en)
|
2000-10-06 |
2017-07-18 |
The Trustees Of Columbia University In The City Of New York |
Massive parallel method for decoding DNA and RNA
|
|
ATE356222T1
(de)
|
2000-10-06 |
2007-03-15 |
Univ Columbia |
Massives parallelverfahren zur dekodierung von dna und rna
|
|
US20030027140A1
(en)
|
2001-03-30 |
2003-02-06 |
Jingyue Ju |
High-fidelity DNA sequencing using solid phase capturable dideoxynucleotides and mass spectrometry
|
|
US7041812B2
(en)
|
2001-08-29 |
2006-05-09 |
Amersham Biosciences Corp |
Labeled nucleoside polyphosphates
|
|
DK2431377T3
(en)
|
2001-10-26 |
2017-08-14 |
Noxxon Pharma Ag |
Modified L-nucleic acids
|
|
WO2003064621A2
(en)
|
2002-02-01 |
2003-08-07 |
Ambion, Inc. |
HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES
|
|
US7074597B2
(en)
|
2002-07-12 |
2006-07-11 |
The Trustees Of Columbia University In The City Of New York |
Multiplex genotyping using solid phase capturable dideoxynucleotides and mass spectrometry
|
|
US20090186343A1
(en)
*
|
2003-01-28 |
2009-07-23 |
Visigen Biotechnologies, Inc. |
Methods for preparing modified biomolecules, modified biomolecules and methods for using same
|
|
JP4896708B2
(ja)
*
|
2003-02-05 |
2012-03-14 |
ジーイー・ヘルスケア・バイオサイエンス・コーポレイション |
新規リンカー類を有する末端リン酸標識ヌクレオチド類
|
|
EP1597602A4
(en)
|
2003-02-05 |
2009-07-22 |
Ge Healthcare Bio Sciences |
SOLID PHASE SEQUENCING
|
|
US7365178B2
(en)
*
|
2003-04-01 |
2008-04-29 |
Activx Biosciences, Inc. |
Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
|
|
US7745116B2
(en)
|
2003-04-08 |
2010-06-29 |
Pacific Biosciences Of California, Inc. |
Composition and method for nucleic acid sequencing
|
|
US7019346B2
(en)
|
2003-12-23 |
2006-03-28 |
Intel Corporation |
Capacitor having an anodic metal oxide substrate
|
|
US20050148087A1
(en)
*
|
2004-01-05 |
2005-07-07 |
Applera Corporation |
Isobarically labeled analytes and fragment ions derived therefrom
|
|
CA2557818A1
(en)
|
2004-03-03 |
2005-09-15 |
The Trustees Of Columbia University In The City Of New York |
Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry
|
|
US7279337B2
(en)
|
2004-03-10 |
2007-10-09 |
Agilent Technologies, Inc. |
Method and apparatus for sequencing polymers through tunneling conductance variation detection
|
|
WO2006028508A2
(en)
|
2004-03-23 |
2006-03-16 |
President And Fellows Of Harvard College |
Methods and apparatus for characterizing polynucleotides
|
|
US20050239134A1
(en)
|
2004-04-21 |
2005-10-27 |
Board Of Regents, The University Of Texas System |
Combinatorial selection of phosphorothioate single-stranded DNA aptamers for TGF-beta-1 protein
|
|
GB2431013B
(en)
|
2004-07-23 |
2008-05-21 |
Electronic Bio Sciences Llc |
Method and apparatus for sensing a time varying current passing through an ion channel
|
|
CA2577079C
(en)
|
2004-08-13 |
2014-05-20 |
President And Fellows Of Harvard College |
An ultra high-throughput opti-nanopore dna readout platform
|
|
US20060105461A1
(en)
|
2004-10-22 |
2006-05-18 |
May Tom-Moy |
Nanopore analysis system
|
|
WO2007084103A2
(en)
|
2004-12-21 |
2007-07-26 |
The Texas A & M University System |
High temperature ion channels and pores
|
|
GB0505971D0
(en)
|
2005-03-23 |
2005-04-27 |
Isis Innovation |
Delivery of molecules to a lipid bilayer
|
|
WO2007002204A2
(en)
|
2005-06-21 |
2007-01-04 |
The Trustees Of Columbia University In The City Of New York |
Pyrosequencing methods and related compostions
|
|
US7405281B2
(en)
|
2005-09-29 |
2008-07-29 |
Pacific Biosciences Of California, Inc. |
Fluorescent nucleotide analogs and uses therefor
|
|
WO2007041621A2
(en)
|
2005-10-03 |
2007-04-12 |
Xingsheng Sean Ling |
Hybridization assisted nanopore sequencing
|
|
US7397232B2
(en)
|
2005-10-21 |
2008-07-08 |
The University Of Akron |
Coulter counter having a plurality of channels
|
|
US7982029B2
(en)
|
2005-10-31 |
2011-07-19 |
The Trustees Of Columbia University In The City Of New York |
Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods
|
|
WO2007053719A2
(en)
|
2005-10-31 |
2007-05-10 |
The Trustees Of Columbia University In The City Of New York |
Chemically cleavable 3'-o-allyl-dntp-allyl-fluorophore fluorescent nucleotide analogues and related methods
|
|
EP1963530B1
(en)
|
2005-12-22 |
2011-07-27 |
Pacific Biosciences of California, Inc. |
Active surface coupled polymerases
|
|
US20070298511A1
(en)
|
2006-04-27 |
2007-12-27 |
The Texas A&M University System |
Nanopore sensor system
|
|
US7777505B2
(en)
|
2006-05-05 |
2010-08-17 |
University Of Utah Research Foundation |
Nanopore platforms for ion channel recordings and single molecule detection and analysis
|
|
US8889348B2
(en)
|
2006-06-07 |
2014-11-18 |
The Trustees Of Columbia University In The City Of New York |
DNA sequencing by nanopore using modified nucleotides
|
|
EP1867638A1
(de)
*
|
2006-06-16 |
2007-12-19 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Verfahren zur kovalenten Verknüpfung zweier Moleküle mittels Diels-Alder-Reaktion mit inversem Elektronenbedarf
|
|
DE112007002932B4
(de)
|
2006-12-01 |
2015-08-06 |
The Trustees Of Columbia University In The City Of New York |
Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren
|
|
US7902345B2
(en)
|
2006-12-05 |
2011-03-08 |
Sequenom, Inc. |
Detection and quantification of biomolecules using mass spectrometry
|
|
US8003319B2
(en)
|
2007-02-02 |
2011-08-23 |
International Business Machines Corporation |
Systems and methods for controlling position of charged polymer inside nanopore
|
|
US20100196203A1
(en)
|
2007-02-20 |
2010-08-05 |
Gurdial Singh Sanghera |
Formation of Lipid Bilayers
|
|
WO2008124107A1
(en)
|
2007-04-04 |
2008-10-16 |
The Regents Of The University Of California |
Compositions, devices, systems, and methods for using a nanopore
|
|
EP3543357A1
(en)
|
2007-05-08 |
2019-09-25 |
Trustees of Boston University |
Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
|
|
US20090073293A1
(en)
|
2007-06-27 |
2009-03-19 |
Yoel Yaffe |
CMOS image sensors with increased dynamic range and methods of operating the same
|
|
WO2009046094A1
(en)
|
2007-10-01 |
2009-04-09 |
Nabsys, Inc. |
Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment
|
|
EP2205765B1
(en)
|
2007-10-02 |
2012-09-12 |
President and Fellows of Harvard College |
Capture, recapture, and trapping of molecules with a nanopore
|
|
EP4310194A3
(en)
|
2007-10-19 |
2024-10-16 |
The Trustees of Columbia University in the City of New York |
Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
|
|
US9115163B2
(en)
|
2007-10-19 |
2015-08-25 |
The Trustees Of Columbia University In The City Of New York |
DNA sequence with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
|
|
US20110166043A1
(en)
*
|
2007-11-14 |
2011-07-07 |
Jon Owen Nagy |
Biomarker detection-2
|
|
GB0724736D0
(en)
|
2007-12-19 |
2008-01-30 |
Oxford Nanolabs Ltd |
Formation of layers of amphiphilic molecules
|
|
US20110165652A1
(en)
*
|
2008-01-14 |
2011-07-07 |
Life Technologies Corporation |
Compositions, methods and systems for single molecule sequencing
|
|
DE102008006990A1
(de)
*
|
2008-01-31 |
2009-08-06 |
Osram Opto Semiconductors Gmbh |
Hintergrundbeleuchtungseinheit für eine Hintergrundbeleuchtung eines Bildschirms und Bildschirmeinheit des Bildschirms
|
|
ATE530497T1
(de)
|
2008-03-31 |
2011-11-15 |
Sony Deutschland Gmbh |
Verfahren zur herstellung einer membran mit konischer pore
|
|
EP2274446B1
(en)
|
2008-03-31 |
2015-09-09 |
Pacific Biosciences of California, Inc. |
Two slow-step polymerase enzyme systems and methods
|
|
WO2009134469A1
(en)
|
2008-04-29 |
2009-11-05 |
Life Technologies |
Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use
|
|
RU2487877C2
(ru)
*
|
2008-04-30 |
2013-07-20 |
Иммьюноджен, Инк. |
Высокоэффективные конъюгаты и гидрофильные сшивающие агенты (линкеры)
|
|
US8940142B2
(en)
|
2008-05-05 |
2015-01-27 |
The Regents Of The University Of California |
Functionalized nanopipette biosensor
|
|
EP2307540B1
(en)
|
2008-07-07 |
2017-04-19 |
Oxford Nanopore Technologies Limited |
Enzyme-pore constructs
|
|
JP5596684B2
(ja)
*
|
2008-08-12 |
2014-09-24 |
エフ．ホフマン−ラ ロシュ アーゲー |
プルーフリーディング・プライマー伸長
|
|
US8921046B2
(en)
|
2008-09-19 |
2014-12-30 |
Pacific Biosciences Of California, Inc. |
Nucleic acid sequence analysis
|
|
US20100148126A1
(en)
|
2008-11-26 |
2010-06-17 |
Board Of Regents, The University Of Texas System |
Genomic sequencing using modified protein pores and ionic liquids
|
|
US20100227414A1
(en)
|
2009-03-05 |
2010-09-09 |
Trex Enterprises Corp. |
Affinity capture mass spectroscopy with a porous silicon biosensor
|
|
GB0905140D0
(en)
|
2009-03-25 |
2009-05-06 |
Isis Innovation |
Method
|
|
EP2239053A1
(en)
*
|
2009-04-09 |
2010-10-13 |
baseclick GmbH |
Click chemistry on heterogeneous catalysts
|
|
US8986928B2
(en)
|
2009-04-10 |
2015-03-24 |
Pacific Biosciences Of California, Inc. |
Nanopore sequencing devices and methods
|
|
US20130053252A1
(en)
|
2009-09-25 |
2013-02-28 |
President & Fellows Of Harvard College |
Nucleic acid amplification and sequencing by synthesis with fluorogenic nucleotides
|
|
EP2516386B1
(en)
*
|
2009-12-23 |
2015-04-22 |
Life Technologies Corporation |
Protein modification from the oxidation of clickable polyunsaturated fatty acid analogs
|
|
EP2360167A1
(en)
*
|
2010-02-03 |
2011-08-24 |
Deutsches Krebsforschungszentrum |
Post-synthetic modification of nucleic acids by inverse Diels-Alder reaction
|
|
US20110287414A1
(en)
|
2010-02-08 |
2011-11-24 |
Genia Technologies, Inc. |
Systems and methods for identifying a portion of a molecule
|
|
US9605307B2
(en)
|
2010-02-08 |
2017-03-28 |
Genia Technologies, Inc. |
Systems and methods for forming a nanopore in a lipid bilayer
|
|
CA2995178C
(en)
|
2010-02-08 |
2023-09-12 |
Genia Technologies, Inc. |
Method and system for forming a nanopore in a lipid bilayer
|
|
US20110192723A1
(en)
|
2010-02-08 |
2011-08-11 |
Genia Technologies, Inc. |
Systems and methods for manipulating a molecule in a nanopore
|
|
US20120052188A1
(en)
|
2010-02-08 |
2012-03-01 |
Genia Technologies, Inc. |
Systems and methods for assembling a lipid bilayer on a substantially planar solid surface
|
|
US8324914B2
(en)
|
2010-02-08 |
2012-12-04 |
Genia Technologies, Inc. |
Systems and methods for characterizing a molecule
|
|
US9234930B2
(en)
|
2010-02-10 |
2016-01-12 |
Lattice Semiconductor Corporation |
Determination of physical connectivity status of devices based on electrical measurement
|
|
WO2011106456A2
(en)
|
2010-02-23 |
2011-09-01 |
University Of Washington |
Artificial mycolic acid membranes
|
|
US8652779B2
(en)
|
2010-04-09 |
2014-02-18 |
Pacific Biosciences Of California, Inc. |
Nanopore sequencing using charge blockade labels
|
|
EP3190193A1
(en)
|
2010-07-14 |
2017-07-12 |
The Curators Of The University Of Missouri |
Nanopore-facilitated single molecule detection of nucleic acids
|
|
WO2012012612A2
(en)
*
|
2010-07-23 |
2012-01-26 |
University Of Delaware |
Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes
|
|
EP2652153B1
(en)
*
|
2010-12-17 |
2017-07-05 |
The Trustees of Columbia University in the City of New York |
Dna sequencing by synthesis using modified nucleotides and nanopore detection
|
|
WO2012088339A2
(en)
|
2010-12-22 |
2012-06-28 |
Genia Technologies, Inc. |
Nanopore-based single dna molecule characterization using speed bumps
|
|
US8962242B2
(en)
|
2011-01-24 |
2015-02-24 |
Genia Technologies, Inc. |
System for detecting electrical properties of a molecular complex
|
|
US9110478B2
(en)
|
2011-01-27 |
2015-08-18 |
Genia Technologies, Inc. |
Temperature regulation of measurement arrays
|
|
WO2012109574A2
(en)
|
2011-02-11 |
2012-08-16 |
Nabsys, Inc. |
Assay methods using dna binding proteins
|
|
US9150912B2
(en)
*
|
2011-05-06 |
2015-10-06 |
Qiagen Gmbh |
Oligonucleotides comprising a label associated through a linker
|
|
US9624539B2
(en)
|
2011-05-23 |
2017-04-18 |
The Trustees Of Columbia University In The City Of New York |
DNA sequencing by synthesis using Raman and infrared spectroscopy detection
|
|
CN104011866B
(zh)
|
2011-07-27 |
2017-06-09 |
伊利诺伊大学评议会 |
用于生物分子表征的纳米孔传感器
|
|
WO2013109970A1
(en)
|
2012-01-20 |
2013-07-25 |
Genia Technologies, Inc. |
Nanopore based molecular detection and sequencing
|
|
US8541849B2
(en)
|
2012-02-14 |
2013-09-24 |
Genia Technologies, Inc. |
Noise shielding techniques for ultra low current measurements in biochemical applications
|
|
EP2814983B1
(en)
|
2012-02-16 |
2019-04-24 |
Genia Technologies, Inc. |
Methods for creating bilayers for use with nanopore sensors
|
|
US10246479B2
(en)
|
2012-04-09 |
2019-04-02 |
The Trustees Of Columbia University In The City Of New York |
Method of preparation of nanopore and uses thereof
|
|
GB2510719A
(en)
|
2012-06-15 |
2014-08-13 |
Genia Technologies Inc |
Chip set-up and high-accuracy nucleic acid sequencing
|
|
EP2864502B1
(en)
|
2012-06-20 |
2019-10-23 |
The Trustees of Columbia University in the City of New York |
Nucleic acid sequencing by nanopore detection of tag molecules
|
|
US9605309B2
(en)
|
2012-11-09 |
2017-03-28 |
Genia Technologies, Inc. |
Nucleic acid sequencing using tags
|
|
WO2014081301A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Bio-orthogonal drug activation
|
|
WO2014117001A1
(en)
|
2013-01-25 |
2014-07-31 |
Memorial Sloan-Kettering Cancer Center |
Tetrazines/trans-cyclooctenes in solid phase synthesis of labeled peptides
|
|
US10648026B2
(en)
|
2013-03-15 |
2020-05-12 |
The Trustees Of Columbia University In The City Of New York |
Raman cluster tagged molecules for biological imaging
|
|
CN105102627B
(zh)
|
2013-03-15 |
2018-10-19 |
纽约哥伦比亚大学理事会 |
用于检测样品中多种预定化合物的方法
|
|
US10718011B2
(en)
|
2014-02-12 |
2020-07-21 |
The Trustees Of Columbia University In The City Of New York |
Single molecule electronic multiplex SNP assay and PCR analysis
|
|
CA2943952A1
(en)
|
2014-03-24 |
2015-10-01 |
The Trustees Of Columbia University In The City Of New York |
Chemical methods for producing tagged nucleotides
|
|
US20170101675A1
(en)
|
2014-05-19 |
2017-04-13 |
The Trustees Of Columbia University In The City Of New York |
Ion sensor dna and rna sequencing by synthesis using nucleotide reversible terminators
|
|
WO2016144973A1
(en)
|
2015-03-09 |
2016-09-15 |
The Trustees Of Columbia University In The City Of New York |
Pore-forming protein conjugate compositions and methods
|
|
WO2016154215A1
(en)
|
2015-03-23 |
2016-09-29 |
The Trustees Of Columbia University In The City Of New York |
Polymer tagged nucleotides for single molecule electronic snp assay
|
|
US11085076B2
(en)
|
2015-09-28 |
2021-08-10 |
The Trustees Of Columbia University In The City Of New York |
Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
|
|
US20180327828A1
(en)
|
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|
|
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|
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|
|
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|
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|
|
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(en)
|
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|
|
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(zh)
|
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