JP2017514854A5 - - Google Patents
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- Publication number
- JP2017514854A5 JP2017514854A5 JP2016566641A JP2016566641A JP2017514854A5 JP 2017514854 A5 JP2017514854 A5 JP 2017514854A5 JP 2016566641 A JP2016566641 A JP 2016566641A JP 2016566641 A JP2016566641 A JP 2016566641A JP 2017514854 A5 JP2017514854 A5 JP 2017514854A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- administered
- antibody
- dose
- functional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 5
- 229940124597 therapeutic agent Drugs 0.000 claims 5
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- 190000008236 carboplatin Chemical compound 0.000 claims 2
- 229960004562 carboplatin Drugs 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- XXJWYDDUDKYVKI-UHFFFAOYSA-N 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline Chemical group COC1=CC2=C(OC=3C(=C4C=C(C)NC4=CC=3)F)N=CN=C2C=C1OCCCN1CCCC1 XXJWYDDUDKYVKI-UHFFFAOYSA-N 0.000 claims 1
- 102100034608 Angiopoietin-2 Human genes 0.000 claims 1
- GAGWJHPBXLXJQN-UORFTKCHSA-N Capecitabine Chemical compound C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1[C@H]1[C@H](O)[C@H](O)[C@@H](C)O1 GAGWJHPBXLXJQN-UORFTKCHSA-N 0.000 claims 1
- GAGWJHPBXLXJQN-UHFFFAOYSA-N Capecitabine Natural products C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1C1C(O)C(O)C(C)O1 GAGWJHPBXLXJQN-UHFFFAOYSA-N 0.000 claims 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 claims 1
- 101000924533 Homo sapiens Angiopoietin-2 Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 229960000397 bevacizumab Drugs 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229960004117 capecitabine Drugs 0.000 claims 1
- 229960002412 cediranib Drugs 0.000 claims 1
- 229960005277 gemcitabine Drugs 0.000 claims 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461989884P | 2014-05-07 | 2014-05-07 | |
| US61/989,884 | 2014-05-07 | ||
| US201462005525P | 2014-05-30 | 2014-05-30 | |
| US62/005,525 | 2014-05-30 | ||
| PCT/US2015/029447 WO2015171747A1 (en) | 2014-05-07 | 2015-05-06 | Methods of using anti-ang2 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017514854A JP2017514854A (ja) | 2017-06-08 |
| JP2017514854A5 true JP2017514854A5 (enExample) | 2018-06-14 |
Family
ID=54392949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566641A Pending JP2017514854A (ja) | 2014-05-07 | 2015-05-06 | 抗ａｎｇ２抗体を用いる方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170058025A1 (enExample) |
| EP (1) | EP3139956A4 (enExample) |
| JP (1) | JP2017514854A (enExample) |
| KR (1) | KR20170003651A (enExample) |
| CN (1) | CN107206067A (enExample) |
| AU (1) | AU2015256052A1 (enExample) |
| CA (1) | CA2946906A1 (enExample) |
| HK (1) | HK1244445A1 (enExample) |
| IL (1) | IL248391A0 (enExample) |
| RU (1) | RU2016147521A (enExample) |
| SG (1) | SG11201609168PA (enExample) |
| WO (1) | WO2015171747A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9732131B2 (en) | 2006-02-27 | 2017-08-15 | Calviri, Inc. | Identification and use of novopeptides for the treatment of cancer |
| CN109863171B (zh) | 2016-08-23 | 2023-08-04 | 免疫医疗有限公司 | 抗vegf-a和抗ang2抗体及其用途 |
| WO2018223094A1 (en) | 2017-06-02 | 2018-12-06 | Arizona Board Of Regents On Behalf Of Arizona State University | A method to create personalized canine cancer vaccines |
| US12025615B2 (en) | 2017-09-15 | 2024-07-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods of classifying response to immunotherapy for cancer |
| CN113728004A (zh) * | 2019-02-25 | 2021-11-30 | 药物抗体公司 | 抗Ang2抗体及其用途 |
| CN118027319A (zh) | 2019-05-08 | 2024-05-14 | 大金工业株式会社 | 含氟聚合物 |
| EP4038222A4 (en) | 2019-10-02 | 2023-10-18 | Arizona Board of Regents on behalf of Arizona State University | Methods and compositions for identifying neoantigens for use in treating and preventing cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2712000A1 (en) * | 2008-01-28 | 2009-08-06 | Medimmune Limited | Stabilized angiopoietin-2 antibodies and uses thereof |
| US8980268B2 (en) * | 2009-07-29 | 2015-03-17 | Regeneron Pharamceuticals, Inc. | Methods for treating cancer by administering an anti-Ang-2 antibody |
| JO3182B1 (ar) * | 2009-07-29 | 2018-03-08 | Regeneron Pharma | مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2 |
| MA34059B1 (fr) * | 2010-02-23 | 2013-03-05 | Genentech Inc | Thérapie anti-angiogénique pour le traitement du cancer des ovaires |
| CN102250247B (zh) * | 2011-06-15 | 2013-06-19 | 常州亚当生物技术有限公司 | 一种抗vegf/ang2双特异性抗体及其应用 |
| EP2783510A1 (en) * | 2011-11-21 | 2014-10-01 | Motorola Mobility LLC | Implicit determination and combined implicit and explicit determination of collocated picture for temporal prediction |
| JP6464085B2 (ja) * | 2012-08-07 | 2019-02-06 | ジェネンテック， インコーポレイテッド | 神経膠芽腫の治療のための併用療法 |
-
2015
- 2015-05-06 CN CN201580035986.9A patent/CN107206067A/zh active Pending
- 2015-05-06 US US15/308,187 patent/US20170058025A1/en not_active Abandoned
- 2015-05-06 CA CA2946906A patent/CA2946906A1/en not_active Abandoned
- 2015-05-06 JP JP2016566641A patent/JP2017514854A/ja active Pending
- 2015-05-06 KR KR1020167034326A patent/KR20170003651A/ko not_active Ceased
- 2015-05-06 AU AU2015256052A patent/AU2015256052A1/en not_active Abandoned
- 2015-05-06 RU RU2016147521A patent/RU2016147521A/ru not_active Application Discontinuation
- 2015-05-06 WO PCT/US2015/029447 patent/WO2015171747A1/en not_active Ceased
- 2015-05-06 EP EP15788683.9A patent/EP3139956A4/en not_active Withdrawn
- 2015-05-06 SG SG11201609168PA patent/SG11201609168PA/en unknown
- 2015-05-06 HK HK18103973.5A patent/HK1244445A1/zh unknown
-
2016
- 2016-10-19 IL IL248391A patent/IL248391A0/en unknown
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