JP2017512301A - フローサイトメータにおける光学系のためのシステム、方法、及び装置 - Google Patents

フローサイトメータにおける光学系のためのシステム、方法、及び装置 Download PDF

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JP2017512301A
JP2017512301A JP2016546478A JP2016546478A JP2017512301A JP 2017512301 A JP2017512301 A JP 2017512301A JP 2016546478 A JP2016546478 A JP 2016546478A JP 2016546478 A JP2016546478 A JP 2016546478A JP 2017512301 A JP2017512301 A JP 2017512301A
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light beam
light
optical system
micrometers
light beams
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JP2017512301A5 (enExample
Inventor
グレゴリー カドゥチャック,
グレゴリー カドゥチャック,
ウェスリー スミス,
ウェスリー スミス,
マイケル ウォード,
マイケル ウォード,
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ライフ テクノロジーズ コーポレーション
ライフ テクノロジーズ コーポレーション
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Publication of JP2017512301A publication Critical patent/JP2017512301A/ja
Publication of JP2017512301A5 publication Critical patent/JP2017512301A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1438Using two lasers in succession

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  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Optical Measuring Cells (AREA)
JP2016546478A 2014-02-28 2015-01-28 フローサイトメータにおける光学系のためのシステム、方法、及び装置 Pending JP2017512301A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461946579P 2014-02-28 2014-02-28
US61/946,579 2014-02-28
US201462041806P 2014-08-26 2014-08-26
US62/041,806 2014-08-26
PCT/US2015/013279 WO2015130423A1 (en) 2014-02-28 2015-01-28 Systems, methods, and apparatuses for optical systems in flow cytometers

Publications (2)

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JP2017512301A true JP2017512301A (ja) 2017-05-18
JP2017512301A5 JP2017512301A5 (enExample) 2018-02-22

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JP2016546478A Pending JP2017512301A (ja) 2014-02-28 2015-01-28 フローサイトメータにおける光学系のためのシステム、方法、及び装置

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US (2) US10018553B2 (enExample)
EP (1) EP3111193B1 (enExample)
JP (1) JP2017512301A (enExample)
KR (1) KR102366656B1 (enExample)
CN (2) CN106461530B (enExample)
AU (1) AU2015223493A1 (enExample)
MX (1) MX2016011193A (enExample)
RU (1) RU2016131016A (enExample)
SG (1) SG11201605084PA (enExample)
WO (1) WO2015130423A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019148585A (ja) * 2018-01-31 2019-09-05 ジック エンジニアリング ゲーエムベーハーSICK Engineering GmbH 粒子状物質の測定を行うための分析装置
KR20200028748A (ko) * 2018-09-07 2020-03-17 주식회사 더웨이브톡 광학 검출 시스템

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106461530B (zh) 2014-02-28 2020-12-18 生命科技股份有限公司 用于流式细胞仪中的光学系统的系统、方法和设备
CN109381292A (zh) * 2018-10-09 2019-02-26 武汉博激世纪科技有限公司 激光光束耦合输出装置和耦合输出方法
US11169386B2 (en) * 2019-04-24 2021-11-09 Coherent, Inc. Beam forming with focus location adjustment
WO2021099081A1 (en) * 2019-11-22 2021-05-27 Ams Ag Optical based particulate matter sensing

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04142530A (ja) * 1990-10-04 1992-05-15 Seiko Epson Corp 投写型液晶表示装置
JPH04270961A (ja) * 1991-02-27 1992-09-28 Toa Medical Electronics Co Ltd フローイメージサイトメータ
JPH0561129A (ja) * 1991-08-29 1993-03-12 Tamron Co Ltd 投射型表示装置
JPH0643090A (ja) * 1992-04-01 1994-02-18 Toa Medical Electronics Co Ltd 粒子分析装置
JPH08292395A (ja) * 1995-04-20 1996-11-05 Fuji Photo Optical Co Ltd 液晶プロジェクタ
JPH09508703A (ja) * 1994-08-01 1997-09-02 アボツト・ラボラトリーズ フローサイトメトリック血液細胞分析器用の擬似テレセントリック光学設計
JPH10228665A (ja) * 1997-02-12 1998-08-25 Hitachi Ltd 光ディスク装置及びそれに用いる光ヘッド
US5999250A (en) * 1997-03-17 1999-12-07 Tsi Corporation System for detecting fluorescing components in aerosols
JP2004532969A (ja) * 2000-10-12 2004-10-28 アムニス コーポレイション レポーターラベルビードを読み取るための方法および装置
JP2008039539A (ja) * 2006-08-04 2008-02-21 Shimadzu Corp 光散乱検出装置
JP2008089540A (ja) * 2006-10-05 2008-04-17 Furukawa Electric Co Ltd:The 光計測方法および光計測装置
US20110058163A1 (en) * 2007-12-17 2011-03-10 Rich Collin A Optical system for a flow cytometer with an interrogation zone
CN102175587A (zh) * 2010-12-31 2011-09-07 深圳市美思康电子有限公司 用于血液细胞分析、流式细胞分析、体液分析的激光系统

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6975400B2 (en) 1999-01-25 2005-12-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US7050380B2 (en) * 2000-04-18 2006-05-23 Ricoh Company, Ltd. Optical element, optical pickup unit, and optical disk drive unit
JP4994560B2 (ja) * 2000-08-25 2012-08-08 アムニス コーポレイション 細胞などの小さな移動物体の速度測定
US7061614B2 (en) * 2001-10-16 2006-06-13 Therma-Wave, Inc. Measurement system with separate optimized beam paths
US7057822B2 (en) * 2002-02-19 2006-06-06 Unaxis Balzers Ltd. System for projecting an image using narrow band light sources
US8520205B2 (en) 2005-02-09 2013-08-27 Flir Systems, Inc. Method and system for detecting, classifying and identifying particles
FR2884920B1 (fr) * 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
JP4756948B2 (ja) * 2005-08-08 2011-08-24 ベイバイオサイエンス株式会社 フローサイトメータおよびフローサイトメトリ方法
US7411734B2 (en) * 2005-11-10 2008-08-12 3M Innovative Properties Company Color-splitting optical element and an optical system utilizing the color-splitting optical element
EP2024893B1 (en) 2006-05-12 2015-03-04 Janssen Diagnostics, LLC A laser illumination system in fluorescent microscopy
JP5259305B2 (ja) * 2007-10-03 2013-08-07 シスメックス株式会社 細胞分析装置及び細胞分析方法
JP4365439B2 (ja) * 2008-03-04 2009-11-18 三井造船株式会社 蛍光検出方法及び蛍光検出装置
JP4600573B2 (ja) * 2008-05-29 2010-12-15 ソニー株式会社 光学的測定装置、並びに光検出器の波長校正方法及び光学的測定方法
JP5633138B2 (ja) * 2008-12-24 2014-12-03 セイコーエプソン株式会社 照明装置およびプロジェクター
US8376551B2 (en) * 2010-02-25 2013-02-19 Corning Incorporated Illumination system for laser projection
AT510765B1 (de) 2010-12-15 2012-09-15 Wolfgang Dipl Ing Vogl Vorrichtung zur photometrischen bzw. spektrometrischen untersuchung einer flüssigen probe
US9168568B2 (en) * 2012-08-01 2015-10-27 Owl biomedical, Inc. Particle manipulation system with cytometric confirmation
EP3869181A1 (en) 2013-03-14 2021-08-25 Abbott Laboratories Beam shaping optics of flow cytometer systems and methods related thereto
JP5925746B2 (ja) * 2013-10-18 2016-05-25 増田 麻言 レーザ光投射装置および投影装置
US9638988B2 (en) * 2013-12-12 2017-05-02 Corning Incorporated Light multiplexer with color combining element
US9360164B2 (en) * 2013-12-12 2016-06-07 Owl biomedical, Inc. Particle manipulation system with stay-wet algorithm
CN106461530B (zh) 2014-02-28 2020-12-18 生命科技股份有限公司 用于流式细胞仪中的光学系统的系统、方法和设备
US9726593B2 (en) 2014-02-28 2017-08-08 Life Technologies Corporation Systems, methods, and apparatuses for optical systems in flow cytometers
EP3163287B1 (en) * 2015-10-30 2022-03-23 Sysmex Corporation Cell information obtaining method and cell information obtaining apparatus
JP2017146552A (ja) * 2016-02-19 2017-08-24 セイコーエプソン株式会社 照明装置及びプロジェクター

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04142530A (ja) * 1990-10-04 1992-05-15 Seiko Epson Corp 投写型液晶表示装置
JPH04270961A (ja) * 1991-02-27 1992-09-28 Toa Medical Electronics Co Ltd フローイメージサイトメータ
JPH0561129A (ja) * 1991-08-29 1993-03-12 Tamron Co Ltd 投射型表示装置
JPH0643090A (ja) * 1992-04-01 1994-02-18 Toa Medical Electronics Co Ltd 粒子分析装置
JPH09508703A (ja) * 1994-08-01 1997-09-02 アボツト・ラボラトリーズ フローサイトメトリック血液細胞分析器用の擬似テレセントリック光学設計
JPH08292395A (ja) * 1995-04-20 1996-11-05 Fuji Photo Optical Co Ltd 液晶プロジェクタ
JPH10228665A (ja) * 1997-02-12 1998-08-25 Hitachi Ltd 光ディスク装置及びそれに用いる光ヘッド
US5999250A (en) * 1997-03-17 1999-12-07 Tsi Corporation System for detecting fluorescing components in aerosols
JP2004532969A (ja) * 2000-10-12 2004-10-28 アムニス コーポレイション レポーターラベルビードを読み取るための方法および装置
JP2008039539A (ja) * 2006-08-04 2008-02-21 Shimadzu Corp 光散乱検出装置
JP2008089540A (ja) * 2006-10-05 2008-04-17 Furukawa Electric Co Ltd:The 光計測方法および光計測装置
US20110058163A1 (en) * 2007-12-17 2011-03-10 Rich Collin A Optical system for a flow cytometer with an interrogation zone
CN102175587A (zh) * 2010-12-31 2011-09-07 深圳市美思康电子有限公司 用于血液细胞分析、流式细胞分析、体液分析的激光系统

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019148585A (ja) * 2018-01-31 2019-09-05 ジック エンジニアリング ゲーエムベーハーSICK Engineering GmbH 粒子状物質の測定を行うための分析装置
KR20200028748A (ko) * 2018-09-07 2020-03-17 주식회사 더웨이브톡 광학 검출 시스템
KR102130100B1 (ko) 2018-09-07 2020-07-03 주식회사 더웨이브톡 광학 검출 시스템

Also Published As

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CN204649590U (zh) 2015-09-16
SG11201605084PA (en) 2016-09-29
RU2016131016A3 (enExample) 2018-03-29
AU2015223493A1 (en) 2016-10-27
EP3111193A1 (en) 2017-01-04
RU2016131016A (ru) 2018-03-29
WO2015130423A1 (en) 2015-09-03
KR102366656B1 (ko) 2022-02-23
MX2016011193A (es) 2016-12-16
US20180067037A1 (en) 2018-03-08
KR20160126062A (ko) 2016-11-01
CN106461530B (zh) 2020-12-18
US20190033199A1 (en) 2019-01-31
CN106461530A (zh) 2017-02-22
US10018553B2 (en) 2018-07-10
US10473578B2 (en) 2019-11-12
EP3111193B1 (en) 2020-02-26

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