CN106461530B - 用于流式细胞仪中的光学系统的系统、方法和设备 - Google Patents

用于流式细胞仪中的光学系统的系统、方法和设备 Download PDF

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CN106461530B
CN106461530B CN201580010805.7A CN201580010805A CN106461530B CN 106461530 B CN106461530 B CN 106461530B CN 201580010805 A CN201580010805 A CN 201580010805A CN 106461530 B CN106461530 B CN 106461530B
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converging
beams
microns
optical system
light
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CN106461530A (zh
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G·科达查克
W·史密斯
M·沃德
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Life Technologies Corp
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Life Technologies Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession

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  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Optical Measuring Cells (AREA)
CN201580010805.7A 2014-02-28 2015-01-28 用于流式细胞仪中的光学系统的系统、方法和设备 Active CN106461530B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461946579P 2014-02-28 2014-02-28
US61/946,579 2014-02-28
US201462041806P 2014-08-26 2014-08-26
US62/041,806 2014-08-26
PCT/US2015/013279 WO2015130423A1 (en) 2014-02-28 2015-01-28 Systems, methods, and apparatuses for optical systems in flow cytometers

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CN106461530A CN106461530A (zh) 2017-02-22
CN106461530B true CN106461530B (zh) 2020-12-18

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CN201520117517.9U Expired - Lifetime CN204649590U (zh) 2014-02-28 2015-02-27 流式细胞仪中的光学系统

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US (2) US10018553B2 (enExample)
EP (1) EP3111193B1 (enExample)
JP (1) JP2017512301A (enExample)
KR (1) KR102366656B1 (enExample)
CN (2) CN106461530B (enExample)
AU (1) AU2015223493A1 (enExample)
MX (1) MX2016011193A (enExample)
RU (1) RU2016131016A (enExample)
SG (1) SG11201605084PA (enExample)
WO (1) WO2015130423A1 (enExample)

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CN106461530B (zh) 2014-02-28 2020-12-18 生命科技股份有限公司 用于流式细胞仪中的光学系统的系统、方法和设备
EP3521810B1 (de) * 2018-01-31 2019-11-27 SICK Engineering GmbH Analysegerät zur bestimmung von feinstaub
KR102130100B1 (ko) * 2018-09-07 2020-07-03 주식회사 더웨이브톡 광학 검출 시스템
CN109381292A (zh) * 2018-10-09 2019-02-26 武汉博激世纪科技有限公司 激光光束耦合输出装置和耦合输出方法
US11169386B2 (en) * 2019-04-24 2021-11-09 Coherent, Inc. Beam forming with focus location adjustment
WO2021099081A1 (en) * 2019-11-22 2021-05-27 Ams Ag Optical based particulate matter sensing

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CN204649590U (zh) 2015-09-16
SG11201605084PA (en) 2016-09-29
RU2016131016A3 (enExample) 2018-03-29
AU2015223493A1 (en) 2016-10-27
EP3111193A1 (en) 2017-01-04
RU2016131016A (ru) 2018-03-29
WO2015130423A1 (en) 2015-09-03
KR102366656B1 (ko) 2022-02-23
MX2016011193A (es) 2016-12-16
US20180067037A1 (en) 2018-03-08
KR20160126062A (ko) 2016-11-01
US20190033199A1 (en) 2019-01-31
CN106461530A (zh) 2017-02-22
US10018553B2 (en) 2018-07-10
US10473578B2 (en) 2019-11-12
JP2017512301A (ja) 2017-05-18
EP3111193B1 (en) 2020-02-26

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