JP2017509692A5 - - Google Patents

Download PDF

Info

Publication number
JP2017509692A5
JP2017509692A5 JP2016566866A JP2016566866A JP2017509692A5 JP 2017509692 A5 JP2017509692 A5 JP 2017509692A5 JP 2016566866 A JP2016566866 A JP 2016566866A JP 2016566866 A JP2016566866 A JP 2016566866A JP 2017509692 A5 JP2017509692 A5 JP 2017509692A5
Authority
JP
Japan
Prior art keywords
composition
patient
dpp4
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016566866A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017509692A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/012885 external-priority patent/WO2015112970A1/en
Publication of JP2017509692A publication Critical patent/JP2017509692A/ja
Publication of JP2017509692A5 publication Critical patent/JP2017509692A5/ja
Pending legal-status Critical Current

Links

JP2016566866A 2014-01-27 2015-01-26 喘息肺におけるil−13活性化の末梢バイオマーカーとしてのジペプチジルペプチターゼ4(dpp4/cd26) Pending JP2017509692A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461931878P 2014-01-27 2014-01-27
US61/931,878 2014-01-27
US201461990932P 2014-05-09 2014-05-09
US61/990,932 2014-05-09
PCT/US2015/012885 WO2015112970A1 (en) 2014-01-27 2015-01-26 Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung

Publications (2)

Publication Number Publication Date
JP2017509692A JP2017509692A (ja) 2017-04-06
JP2017509692A5 true JP2017509692A5 (https=) 2018-03-08

Family

ID=53682019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016566866A Pending JP2017509692A (ja) 2014-01-27 2015-01-26 喘息肺におけるil−13活性化の末梢バイオマーカーとしてのジペプチジルペプチターゼ4(dpp4/cd26)

Country Status (12)

Country Link
US (1) US20160363591A1 (https=)
EP (2) EP3685857A1 (https=)
JP (1) JP2017509692A (https=)
KR (1) KR20160113700A (https=)
CN (1) CN105934254A (https=)
AU (1) AU2015209124A1 (https=)
BR (1) BR112016017192A2 (https=)
CA (1) CA2937387A1 (https=)
MX (1) MX2016009491A (https=)
RU (1) RU2016134838A (https=)
SG (1) SG11201606102UA (https=)
WO (1) WO2015112970A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015120171A1 (en) 2014-02-07 2015-08-13 Medimmune, Llc Novel assay to detect human periostin
US10351630B2 (en) 2015-01-09 2019-07-16 Medimmune, Llc Assay to detect human DPP-4
JP2018538249A (ja) * 2015-11-04 2018-12-27 アストラゼネカ アクチボラグ 好酸球性疾患における好酸球標的化治療薬に対する臨床応答の予測変数としてのジペプチジルペプチダーゼ−4およびペリオスチン
KR102460040B1 (ko) 2016-04-27 2022-11-01 애브비 인코포레이티드 항-il-13 항체를 이용한 il-13 활성이 유해한 질환의 치료 방법
CN113372446A (zh) 2016-06-08 2021-09-10 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
KR102557643B1 (ko) * 2016-09-23 2023-07-20 제넨테크, 인크. 아토피성 피부염을 치료하기 위한 il-13 길항제의 용도
CA3049847A1 (en) 2017-02-24 2018-08-30 Trustees Of Boston University Isolation of human lung progenitors derived from pluripotent stem cells
CN109055522A (zh) * 2018-07-03 2018-12-21 吉林大学 C4orf38在制备用于检测或治疗神经性疼痛的产品中的应用
KR102330596B1 (ko) 2018-11-09 2021-11-26 아주대학교산학협력단 인간 il-4 수용체 알파에 대한 고친화도 인간 항체 및 이의 용도
CN113155996A (zh) * 2021-03-23 2021-07-23 广州医科大学附属第一医院(广州呼吸中心) 15(s)-羟基二十碳四烯酸在评估变应原特异性免疫治疗效果中的应用
IL317083A (en) 2022-06-17 2025-01-01 Apogee Biologics Inc Antibodies that bind interleukin 13 and methods of use
CN117517676A (zh) * 2022-09-23 2024-02-06 上海市第十人民医院 蛋白生物标志物golm1在克罗恩病临床诊断中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
EP1631680A2 (en) * 2003-05-21 2006-03-08 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase iv (dpp4)
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
WO2005080601A2 (en) * 2004-02-23 2005-09-01 Erasmus Universiteit Rotterdam Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling
WO2008073463A2 (en) * 2006-12-11 2008-06-19 Wyeth Methods and compositions for treating and monitoring treatment of il-13-associated disorders
WO2008091814A2 (en) * 2007-01-22 2008-07-31 Wyeth Assessment of asthma and allergen-dependent gene expression
WO2008097198A1 (en) * 2007-02-09 2008-08-14 Agency For Science, Technology And Research Apparatus and method for analysis of data traffic
CN110079598A (zh) * 2007-10-23 2019-08-02 临床基因组学有限公司 诊断新生物的方法–ii
EP2631302A3 (en) 2008-03-31 2014-01-08 Genentech, Inc. Compositions and methods for treating and diagnosing asthma
US20100221752A2 (en) 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
MX2013004212A (es) * 2010-10-15 2013-09-02 Medimmune Ltd Terapias para mejorar la funcion pulmonar.
TWI732259B (zh) 2010-12-16 2021-07-01 美商建南德克公司 關於th2抑制作用之診斷及治療
EP2710370A4 (en) 2011-05-18 2015-01-07 Medimmune Llc METHODS OF DIAGNOSING AND TREATING PULMONARY DISEASES OR DISORDERS

Similar Documents

Publication Publication Date Title
JP2017509692A5 (https=)
Cao et al. Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17A
O'Byrne et al. Asthma progression and mortality: the role of inhaled corticosteroids
RU2016134838A (ru) Дипептидил пептидаза-4 (dpp4/cd26) как периферический биомаркер активации il-13 в астматическом легком
Jonstam et al. Dupilumab reduces local type 2 pro‐inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis
Buhl et al. Severe eosinophilic asthma: a roadmap to consensus
JP6457463B2 (ja) 処置方法
Chung New treatments for severe treatment-resistant asthma: targeting the right patient
de Groot et al. Management of the patient with eosinophilic asthma: a new era begins
Opina et al. Phenotype-driven therapeutics in severe asthma
EP2627673B1 (en) Therapies for improving pulmonary function
JP2018533557A5 (https=)
CN107073114B (zh) 使用瑞利珠单抗治疗中度到重度嗜酸细胞性哮喘
JP2017036296A (ja) 抗il−5抗体を投与するための方法
Sposato et al. Effects of omalizumab in severe asthmatics across ages: a real life Italian experience
Yilmaz et al. Efficacy of mepolizumab treatment in oral corticosteroid-dependent severe eosinophilicasthma patients with chronic rhinosinusitis with nasal polyps: single center, real life study
Tagaya et al. Effect of tiotropium on mucus hypersecretion and airway clearance in patients with COPD
KR20240049348A (ko) 항-인터루킨-33 항체를 사용한 만성 폐쇄성 폐질환의 치료
Pavord et al. Emerging biologics in severe asthma
Li Targeting the IL-4/IL-4R Axis in Th2 Inflammatory Diseases: A Review of Clinical Efficacy and Safety
US11224653B2 (en) Treatment strategy for non-responders to 100MG subcutaneous mepolizumab
Rupani et al. Eosinophilic asthma
Mastalerz et al. Effect of inhaled corticosteroids on small airway inflammation in patients with bronchial asthma
Moslem et al. Evaluation of Effectiveness of Dexamethasone versus Hydrocortisone in Reducing Hospital Length, Peak Expiratory Flow, Oxidative Stress Factors and Inflammatory Mediators in Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Patients: A Randomized Controlled Trial
MOELAMSYAH et al. Late-Onset Asthma: A Review