JP2017505624A5 - - Google Patents
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- Publication number
- JP2017505624A5 JP2017505624A5 JP2016549436A JP2016549436A JP2017505624A5 JP 2017505624 A5 JP2017505624 A5 JP 2017505624A5 JP 2016549436 A JP2016549436 A JP 2016549436A JP 2016549436 A JP2016549436 A JP 2016549436A JP 2017505624 A5 JP2017505624 A5 JP 2017505624A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acid
- protease
- acid sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 27
- 102000004196 processed proteins & peptides Human genes 0.000 claims 27
- 108090000765 processed proteins & peptides Proteins 0.000 claims 27
- 150000001413 amino acids Chemical group 0.000 claims 10
- 108091005804 Peptidases Proteins 0.000 claims 6
- 239000004365 Protease Substances 0.000 claims 6
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 5
- 108090000631 Trypsin Proteins 0.000 claims 4
- 102000004142 Trypsin Human genes 0.000 claims 4
- 230000004927 fusion Effects 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 239000012588 trypsin Substances 0.000 claims 4
- 206010061598 Immunodeficiency Diseases 0.000 claims 3
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 3
- 208000031951 Primary immunodeficiency Diseases 0.000 claims 3
- 230000007813 immunodeficiency Effects 0.000 claims 3
- 230000000813 microbial effect Effects 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 108090000317 Chymotrypsin Proteins 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 229960002376 chymotrypsin Drugs 0.000 claims 2
- 208000029483 Acquired immunodeficiency Diseases 0.000 claims 1
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 101000898643 Candida albicans Vacuolar aspartic protease Proteins 0.000 claims 1
- 101000898783 Candida tropicalis Candidapepsin Proteins 0.000 claims 1
- 208000003322 Coinfection Diseases 0.000 claims 1
- 101000898784 Cryphonectria parasitica Endothiapepsin Proteins 0.000 claims 1
- 102000005927 Cysteine Proteases Human genes 0.000 claims 1
- 108010005843 Cysteine Proteases Proteins 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- 102000005741 Metalloproteases Human genes 0.000 claims 1
- 108010006035 Metalloproteases Proteins 0.000 claims 1
- 208000031888 Mycoses Diseases 0.000 claims 1
- 206010061324 Oral fungal infection Diseases 0.000 claims 1
- 208000036071 Rhinorrhea Diseases 0.000 claims 1
- 206010039101 Rhinorrhoea Diseases 0.000 claims 1
- 101000933133 Rhizopus niveus Rhizopuspepsin-1 Proteins 0.000 claims 1
- 101000910082 Rhizopus niveus Rhizopuspepsin-2 Proteins 0.000 claims 1
- 101000910079 Rhizopus niveus Rhizopuspepsin-3 Proteins 0.000 claims 1
- 101000910086 Rhizopus niveus Rhizopuspepsin-4 Proteins 0.000 claims 1
- 101000910088 Rhizopus niveus Rhizopuspepsin-5 Proteins 0.000 claims 1
- 101000898773 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Saccharopepsin Proteins 0.000 claims 1
- 206010054979 Secondary immunodeficiency Diseases 0.000 claims 1
- 108010022999 Serine Proteases Proteins 0.000 claims 1
- 102000012479 Serine Proteases Human genes 0.000 claims 1
- 102000035100 Threonine proteases Human genes 0.000 claims 1
- 108091005501 Threonine proteases Proteins 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 229940024606 amino acid Drugs 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 229940112822 chewing gum Drugs 0.000 claims 1
- 235000015218 chewing gum Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 229930195712 glutamate Natural products 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000007937 lozenge Substances 0.000 claims 1
- 210000004877 mucosa Anatomy 0.000 claims 1
- 239000007922 nasal spray Substances 0.000 claims 1
- 229940097496 nasal spray Drugs 0.000 claims 1
- 239000000668 oral spray Substances 0.000 claims 1
- 229940041678 oral spray Drugs 0.000 claims 1
- 235000010603 pastilles Nutrition 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201401480A GB201401480D0 (en) | 2014-01-29 | 2014-01-29 | Novel treatments |
| GB1401480.7 | 2014-01-29 | ||
| GBGB1405784.8A GB201405784D0 (en) | 2014-03-31 | 2014-03-31 | Novel methods, polypeptides and uses thereof |
| GB1405784.8 | 2014-03-31 | ||
| PCT/GB2015/050212 WO2015114343A1 (en) | 2014-01-29 | 2015-01-29 | Novel treatments |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017505624A JP2017505624A (ja) | 2017-02-23 |
| JP2017505624A5 true JP2017505624A5 (cg-RX-API-DMAC7.html) | 2018-03-08 |
| JP6718375B2 JP6718375B2 (ja) | 2020-07-08 |
Family
ID=52630400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549436A Active JP6718375B2 (ja) | 2014-01-29 | 2015-01-29 | 新規治療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20160339087A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3932420A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6718375B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160108560A (cg-RX-API-DMAC7.html) |
| CN (1) | CN106232810A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015212554B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016017478A2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3099317T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2890555T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX384716B (cg-RX-API-DMAC7.html) |
| PL (1) | PL3099317T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3099317T (cg-RX-API-DMAC7.html) |
| RU (1) | RU2732378C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015114343A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201405784D0 (en) * | 2014-03-31 | 2014-05-14 | Enzymatica Ab | Novel methods, polypeptides and uses thereof |
| EP3120866A1 (en) | 2015-07-24 | 2017-01-25 | Zymetech ehf. | Use of marine serine proteases for removal, prevention and inhibition of formation and growth of biofilms |
| GB201701315D0 (en) * | 2017-01-26 | 2017-03-15 | Enzymatica Ab | Novel treatments |
| JP2022502466A (ja) * | 2018-10-11 | 2022-01-11 | モメンタ ファーマシューティカルズ インコーポレイテッド | 高度にシリル化されたＩｇＧ組成物による処理 |
| BR112021016996A8 (pt) | 2019-02-28 | 2022-11-22 | Dandi Bioscience Inc | Polipeptídeo com atividade antibacteriana, composição para prevenir ou tratar sepsis compreendendo a mesma e composição antibacteriana |
| KR102368983B1 (ko) * | 2019-02-28 | 2022-03-03 | 단디바이오사이언스 주식회사 | 항균활성을 갖는 폴리펩타이드, 이를 포함하는 패혈증 예방 또는 치료용 조성물, 및 항균용 조성물 |
| CA3177724A1 (en) * | 2020-05-13 | 2021-11-18 | Mats CLARSUND | Protease formulation for treatment of microbial infections |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| SE459005B (sv) | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| JP2003502071A (ja) * | 1999-06-18 | 2003-01-21 | ブジャーナソン・ヨーン・ブラーギ | 魚類セリンプロティナーゼ及びそれらの薬品及び化粧品への利用 |
| NZ523900A (en) * | 2000-07-13 | 2004-02-27 | Jens Christian Jensenius | Isolation and characterisation of a mannan-binding lectin (MBL) associated serine protease (MASP-2) and uses thereof to treat infections |
| US9511125B2 (en) * | 2009-10-21 | 2016-12-06 | Curemark Llc | Methods and compositions for the treatment of influenza |
| WO2012104099A1 (en) * | 2011-02-04 | 2012-08-09 | Glucometrix Ag | Process for the production of recombinant trypsin |
-
2015
- 2015-01-29 AU AU2015212554A patent/AU2015212554B2/en not_active Ceased
- 2015-01-29 ES ES15708564T patent/ES2890555T3/es active Active
- 2015-01-29 PT PT157085648T patent/PT3099317T/pt unknown
- 2015-01-29 US US15/115,065 patent/US20160339087A1/en not_active Abandoned
- 2015-01-29 EP EP21180866.2A patent/EP3932420A1/en not_active Withdrawn
- 2015-01-29 CN CN201580017331.9A patent/CN106232810A/zh active Pending
- 2015-01-29 DK DK15708564.8T patent/DK3099317T3/da active
- 2015-01-29 WO PCT/GB2015/050212 patent/WO2015114343A1/en not_active Ceased
- 2015-01-29 BR BR112016017478A patent/BR112016017478A2/pt not_active IP Right Cessation
- 2015-01-29 EP EP15708564.8A patent/EP3099317B1/en not_active Not-in-force
- 2015-01-29 KR KR1020167023814A patent/KR20160108560A/ko not_active Ceased
- 2015-01-29 JP JP2016549436A patent/JP6718375B2/ja active Active
- 2015-01-29 RU RU2016135003A patent/RU2732378C2/ru active
- 2015-01-29 PL PL15708564T patent/PL3099317T3/pl unknown
- 2015-01-29 MX MX2016009850A patent/MX384716B/es unknown
-
2019
- 2019-04-26 US US16/395,962 patent/US20190343932A1/en not_active Abandoned
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