JP2017503798A5 - - Google Patents
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- Publication number
- JP2017503798A5 JP2017503798A5 JP2016544672A JP2016544672A JP2017503798A5 JP 2017503798 A5 JP2017503798 A5 JP 2017503798A5 JP 2016544672 A JP2016544672 A JP 2016544672A JP 2016544672 A JP2016544672 A JP 2016544672A JP 2017503798 A5 JP2017503798 A5 JP 2017503798A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutical composition
- skin
- compound according
- skin disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 8
- 208000017520 skin disease Diseases 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 201000004624 Dermatitis Diseases 0.000 claims 3
- 208000011219 Netherton syndrome Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- WYFUNPGYPSDKCF-UHFFFAOYSA-N 2-(2-chlorophenyl)-6-ethoxy-7-methoxy-3,1-benzoxazin-4-one Chemical compound C1=C(OC)C(OCC)=CC(C(O2)=O)=C1N=C2C1=CC=CC=C1Cl WYFUNPGYPSDKCF-UHFFFAOYSA-N 0.000 claims 1
- JTQBMTFVGGUDPN-UHFFFAOYSA-N 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,1-benzoxazin-4-one Chemical compound C1=C(OC)C(OCC)=CC(C(O2)=O)=C1N=C2C1=CC=CC=C1SC JTQBMTFVGGUDPN-UHFFFAOYSA-N 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- 206010020649 Hyperkeratosis Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000003251 Pruritus Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 208000010247 contact dermatitis Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 206010020718 hyperplasia Diseases 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1430003-2 | 2014-01-23 | ||
| SE1430003 | 2014-01-23 | ||
| PCT/SE2015/050062 WO2015112081A1 (en) | 2014-01-23 | 2015-01-22 | Benzoxazinone derivatives for treatment of skin diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017503798A JP2017503798A (ja) | 2017-02-02 |
| JP2017503798A5 true JP2017503798A5 (cg-RX-API-DMAC7.html) | 2018-02-15 |
| JP6448651B2 JP6448651B2 (ja) | 2019-01-09 |
Family
ID=53681747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544672A Active JP6448651B2 (ja) | 2014-01-23 | 2015-01-22 | 皮膚病の処置のためのベンゾオキサジノン誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9695194B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3097085B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6448651B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN106132941B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015209761B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2934025C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1123477T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3097085T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2820868T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20201500T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE051296T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT3097085T (cg-RX-API-DMAC7.html) |
| PL (1) | PL3097085T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3097085T (cg-RX-API-DMAC7.html) |
| RS (1) | RS60830B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI3097085T1 (cg-RX-API-DMAC7.html) |
| SM (1) | SMT202000557T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015112081A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6448651B2 (ja) * | 2014-01-23 | 2019-01-09 | シクセラ ファーマ エービー | 皮膚病の処置のためのベンゾオキサジノン誘導体 |
| KR102579996B1 (ko) * | 2015-05-13 | 2023-09-18 | 니혼노야쿠가부시키가이샤 | 안트라닐산 에스테르 화합물 또는 이의 염류 및 해당 화합물을 함유하는 농원예용 살균제 및 이의 사용 방법 |
| US10821094B2 (en) * | 2016-01-13 | 2020-11-03 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
| KR20250070121A (ko) * | 2017-06-16 | 2025-05-20 | 아지트라 인코포레이티드 | Lekti 발현 재조합 미생물을 사용하는 네테르톤 증후군의 치료를 위한 조성물 및 방법 |
| US20200040103A1 (en) | 2018-03-14 | 2020-02-06 | Genentech, Inc. | Anti-klk5 antibodies and methods of use |
| EP3781588B1 (en) | 2018-04-20 | 2024-10-30 | Children's Hospital Medical Center | Blood biomarker for eosinophilic gastrointestinal disorders |
| GB201809378D0 (en) | 2018-06-07 | 2018-07-25 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US12297501B2 (en) | 2019-02-25 | 2025-05-13 | Children's Hospital Medical Center | Methods for diagnosing and treating eosinophilic gastritis |
| JP2022549087A (ja) | 2019-09-18 | 2022-11-24 | ジェネンテック， インコーポレイテッド | 抗ｋｌｋ７抗体、抗ｋｌｋ５抗体、多重特異性抗ｋｌｋ５／ｋｌｋ７抗体および使用方法 |
| CN114615984B (zh) * | 2019-10-01 | 2025-02-07 | 分子皮肤治疗公司 | 作为klk5/7双重抑制剂的苯并噁嗪酮化合物 |
| GB202001447D0 (en) * | 2020-02-03 | 2020-03-18 | Ucb Biopharma Sprl | Antibodies |
| BR102020009679A2 (pt) | 2020-05-14 | 2021-11-23 | Fundação Universidade Federal Do Abc - Ufabc | Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele |
| TW202304890A (zh) * | 2021-04-14 | 2023-02-01 | 美商百歐克斯製藥公司 | Klk5雙環雜芳香族抑制劑 |
| JP2024520154A (ja) | 2021-06-01 | 2024-05-21 | シクセラ・ファーマ・アーベー | ６－エトキシ－７－メトキシ－２－（２－メチルスルファニルフェニル）－３，１－ベンゾオキサジン－４－オンの水中油型乳剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB115399A (en) * | 1917-03-28 | 1918-04-29 | Reginald Guley Lewis | Improved Delivery mechanism for Coin-freed Apparatus and the like. |
| GB1153994A (en) * | 1965-07-21 | 1969-06-04 | Aspro Nicholas Ltd | Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them |
| WO1999048878A1 (en) * | 1998-03-24 | 1999-09-30 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| PL1631295T3 (pl) * | 2003-06-06 | 2010-09-30 | Arexis Ab | Zastosowanie skondensowanych związków heterocyklicznych jako inhibitorów SCCE do leczenia chorób skóry |
| TWI419884B (zh) | 2010-06-24 | 2013-12-21 | Univ Chang Gung | 苯并雜氧嗪酮衍生物，其製備方法以及包含有此等衍生物的藥學組成物 |
| JP6448651B2 (ja) * | 2014-01-23 | 2019-01-09 | シクセラ ファーマ エービー | 皮膚病の処置のためのベンゾオキサジノン誘導体 |
-
2015
- 2015-01-22 JP JP2016544672A patent/JP6448651B2/ja active Active
- 2015-01-22 ES ES15740572T patent/ES2820868T3/es active Active
- 2015-01-22 AU AU2015209761A patent/AU2015209761B2/en active Active
- 2015-01-22 HR HRP20201500TT patent/HRP20201500T1/hr unknown
- 2015-01-22 SI SI201531393T patent/SI3097085T1/sl unknown
- 2015-01-22 EP EP15740572.1A patent/EP3097085B1/en active Active
- 2015-01-22 WO PCT/SE2015/050062 patent/WO2015112081A1/en not_active Ceased
- 2015-01-22 PL PL15740572T patent/PL3097085T3/pl unknown
- 2015-01-22 CA CA2934025A patent/CA2934025C/en active Active
- 2015-01-22 CN CN201580005383.4A patent/CN106132941B/zh active Active
- 2015-01-22 LT LTEP15740572.1T patent/LT3097085T/lt unknown
- 2015-01-22 US US15/113,750 patent/US9695194B2/en active Active
- 2015-01-22 SM SM20200557T patent/SMT202000557T1/it unknown
- 2015-01-22 PT PT157405721T patent/PT3097085T/pt unknown
- 2015-01-22 HU HUE15740572A patent/HUE051296T2/hu unknown
- 2015-01-22 RS RS20201128A patent/RS60830B1/sr unknown
- 2015-01-22 DK DK15740572.1T patent/DK3097085T3/da active
-
2017
- 2017-06-05 US US15/614,462 patent/US10072024B2/en active Active
-
2020
- 2020-10-20 CY CY20201100988T patent/CY1123477T1/el unknown
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